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Search results 1 to 100 out of 359 for Gdf11

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:3654017
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3654466
Age: embryonic day 17.5
Image: 2
Specimen Label: GDF11
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3654017
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:3654519
Age: embryonic day 11.5
Image: 2
Specimen Label: GDF11
Detected: true
Specimen Num: 2
Publication  
First Author: Pan C
Year: 2020
Journal: JCI Insight
Title: Prostate tumor-derived GDF11 accelerates androgen deprivation therapy-induced sarcopenia.
Volume: 5
Issue: 6
Publication
First Author: Mayweather BA
Year: 2021
Journal: Mol Brain
Title: GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis.
Volume: 14
Issue: 1
Pages: 134
Publication
First Author: Hammers DW
Year: 2017
Journal: EMBO Mol Med
Title: Supraphysiological levels of GDF11 induce striated muscle atrophy.
Volume: 9
Issue: 4
Pages: 531-544
Publication  
First Author: Lian J
Year: 2023
Journal: Life Sci Alliance
Title: Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
Volume: 6
Issue: 3
Publication
First Author: Wang DX
Year: 2023
Journal: Nat Commun
Title: GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21.
Volume: 14
Issue: 1
Pages: 7476
Publication
First Author: Pons M
Year: 2018
Journal: Surgery
Title: GDF11 induces kidney fibrosis, renal cell epithelial-to-mesenchymal transition, and kidney dysfunction and failure.
Volume: 164
Issue: 2
Pages: 262-273
Publication
First Author: Kim J
Year: 2005
Journal: Science
Title: GDF11 controls the timing of progenitor cell competence in developing retina.
Volume: 308
Issue: 5730
Pages: 1927-30
Publication
First Author: Katsimpardi L
Year: 2020
Journal: Aging Cell
Title: Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice.
Volume: 19
Issue: 1
Pages: e13038
Publication
First Author: Li H
Year: 2017
Journal: Diabetes
Title: GDF11 Attenuates Development of Type 2 Diabetes via Improvement of Islet β-Cell Function and Survival.
Volume: 66
Issue: 7
Pages: 1914-1927
Publication
First Author: Shi Y
Year: 2011
Journal: J Neurosci
Title: Gdf11 facilitates temporal progression of neurogenesis in the developing spinal cord.
Volume: 31
Issue: 3
Pages: 883-93
Publication
First Author: Oh SP
Year: 2002
Journal: Genes Dev
Title: Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.
Volume: 16
Issue: 21
Pages: 2749-54
Publication
First Author: Tsuda T
Year: 2011
Journal: Eur J Pediatr Surg
Title: PCSK5 and GDF11 expression in the hindgut region of mouse embryos with anorectal malformations.
Volume: 21
Issue: 4
Pages: 238-41
Publication
First Author: Harmon EB
Year: 2004
Journal: Development
Title: GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development.
Volume: 131
Issue: 24
Pages: 6163-74
Publication
First Author: Gokoffski KK
Year: 2011
Journal: Development
Title: Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate.
Volume: 138
Issue: 19
Pages: 4131-42
Publication
First Author: Essalmani R
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate.
Volume: 105
Issue: 15
Pages: 5750-5
Publication
First Author: Goldstein JM
Year: 2019
Journal: Sci Rep
Title: Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Volume: 9
Issue: 1
Pages: 18613
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190387
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gdf11
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190387
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gdf11
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190387
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gdf11
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190387
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gdf11
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190387
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gdf11
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190387
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gdf11
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6173444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190387
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gdf11
Detected: true
Specimen Num: 7
Publication  
First Author: Santos R
Year: 2012
Journal: Adv Exp Med Biol
Title: Restoration of retinal development in Vsx2 deficient mice by reduction of Gdf11 levels.
Volume: 723
Pages: 671-7
Publication
First Author: Suh J
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone.
Volume: 117
Issue: 9
Pages: 4910-4920
Publication      
First Author: Starcher AE
Year: 2021
Journal: G3 (Bethesda)
Title: A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin.
GXD Expression
Probe: MGI:6432810
Assay Type: RNA in situ
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6434020
Age: embryonic day 10.5
Image: 2K left
Note: Enrichment of Gdf11 expression was detected in the tail tip.
Specimen Label: 2K left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6432810
Assay Type: RNA in situ
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6434020
Age: embryonic day 10.5
Image: 2K center
Note: Enrichment of Gdf11 expression was detected in the tail tip.
Specimen Label: 2K center
Detected: true
Specimen Num: 2
Publication
First Author: Garbern J
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Analysis of Cre-mediated genetic deletion of Gdf11 in cardiomyocytes of young mice.
Volume: 317
Issue: 1
Pages: H201-H212
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L left
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L left
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L center
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L center
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L center
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L center
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L right
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L right
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3594417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L left
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L left
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6432811
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6434027
Age: embryonic day 10.5
Image: 2L center
Note: The expression pattern of the Gfp probe was similar to Gdf11 in the knockin line #1B heterozygous embryos. Gfp expression recapitulates Gdf11 expression.
Specimen Label: 2L center
Detected: true
Specimen Num: 2
Publication
First Author: Guerra A
Year: 2019
Journal: Blood
Title: Lack of Gdf11 does not improve anemia or prevent the activity of RAP-536 in a mouse model of β-thalassemia.
Volume: 134
Issue: 6
Pages: 568-572
Publication
First Author: Nakashima M
Year: 1999
Journal: Mech Dev
Title: Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis.
Volume: 80
Issue: 2
Pages: 185-9
Publication
First Author: Dussiot M
Year: 2014
Journal: Nat Med
Title: An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.
Volume: 20
Issue: 4
Pages: 398-407
Publication
First Author: Suh J
Year: 2019
Journal: J Cell Physiol
Title: Growth differentiation factor 11 locally controls anterior-posterior patterning of the axial skeleton.
Volume: 234
Issue: 12
Pages: 23360-23368
Publication
First Author: Sun J
Year: 2022
Journal: Aging Cell
Title: Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy.
Volume: 21
Issue: 1
Pages: e13532
Publication    
First Author: Bajikar SS
Year: 2023
Journal: Elife
Title: MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function.
Volume: 12
Publication
First Author: Goldstein JM
Year: 2019
Journal: Blood
Title: Steady-state and regenerative hematopoiesis occurs normally in mice in the absence of GDF11.
Volume: 134
Issue: 20
Pages: 1712-1716
Publication  
First Author: McPherron AC
Year: 2009
Journal: BMC Dev Biol
Title: Redundancy of myostatin and growth/differentiation factor 11 function.
Volume: 9
Pages: 24
Publication
First Author: Suragani RN
Year: 2014
Journal: Nat Med
Title: Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis.
Volume: 20
Issue: 4
Pages: 408-14
Publication
First Author: Gaunt SJ
Year: 2013
Journal: Dev Biol
Title: Direct activation of a mouse Hoxd11 axial expression enhancer by Gdf11/Smad signalling.
Volume: 383
Issue: 1
Pages: 52-60
Publication
First Author: Poggioli T
Year: 2016
Journal: Circ Res
Title: Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
Volume: 118
Issue: 1
Pages: 29-37
Publication
First Author: Andersson O
Year: 2006
Journal: EMBO Rep
Title: Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.
Volume: 7
Issue: 8
Pages: 831-7
Publication
First Author: Wu HH
Year: 2003
Journal: Neuron
Title: Autoregulation of neurogenesis by GDF11.
Volume: 37
Issue: 2
Pages: 197-207
Publication
First Author: Li Z
Year: 2010
Journal: Mol Reprod Dev
Title: Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra.
Volume: 77
Issue: 11
Pages: 990-7
Publication
First Author: Dichmann DS
Year: 2006
Journal: Dev Dyn
Title: Analysis of pancreatic endocrine development in GDF11-deficient mice.
Volume: 235
Issue: 11
Pages: 3016-25
Publication
First Author: Esquela AF
Year: 2003
Journal: Dev Biol
Title: Regulation of metanephric kidney development by growth/differentiation factor 11.
Volume: 257
Issue: 2
Pages: 356-70
Publication
First Author: Jurberg AD
Year: 2013
Journal: Dev Cell
Title: Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos.
Volume: 25
Issue: 5
Pages: 451-62
Publication
First Author: Aires R
Year: 2019
Journal: Dev Cell
Title: Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes.
Volume: 48
Issue: 3
Pages: 383-395.e8
Publication
First Author: McPherron AC
Year: 1999
Journal: Nat Genet
Title: Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.
Volume: 22
Issue: 3
Pages: 260-4
Publication
First Author: Li Z
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation.
Volume: 416
Issue: 3-4
Pages: 289-92
Publication
First Author: Lee YJ
Year: 2010
Journal: Dev Biol
Title: Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development.
Volume: 347
Issue: 1
Pages: 195-203
Publication
First Author: Szumska D
Year: 2008
Journal: Genes Dev
Title: VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.
Volume: 22
Issue: 11
Pages: 1465-77
Publication
First Author: Liu JP
Year: 2006
Journal: Development
Title: The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord.
Volume: 133
Issue: 15
Pages: 2865-74
Publication
First Author: Kawauchi S
Year: 2009
Journal: Development
Title: Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.
Volume: 136
Issue: 9
Pages: 1453-64
Publication
First Author: Oxburgh L
Year: 2004
Journal: Development
Title: TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.
Volume: 131
Issue: 18
Pages: 4593-605
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gamer LW
Year: 1999
Journal: Dev Biol
Title: A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos.
Volume: 208
Issue: 1
Pages: 222-32
Publication
First Author: Gad JM
Year: 1999
Journal: Curr Biol
Title: Axis development: the mouse becomes a dachshund.
Volume: 9
Issue: 20
Pages: R783-6
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Stage: TS20
Assay Id: MGI:3706788
Age: embryonic day 12.0
Image: 1
Specimen Label: E12
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3706788
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Stage: TS23
Assay Id: MGI:3706788
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750324
Stage: TS24
Assay Id: MGI:3706788
Age: embryonic day 16.0
Image: 1
Specimen Label: E16
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Stage: TS25
Assay Id: MGI:3706788
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3692549
Assay Type: RT-PCR
Annotation Date: 2007-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:3706788
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 2