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Search results 1 to 100 out of 254 for Gdf15

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0.036s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:3654018
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:3654520
Age: embryonic day 11.5
Image: 2
Specimen Label: GDF15
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3654018
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3654467
Age: embryonic day 17.5
Image: 2
Specimen Label: GDF15
Detected: true
Specimen Num: 2
Publication
First Author: Wang T
Year: 2017
Journal: EMBO Mol Med
Title: GDF15 is a heart-derived hormone that regulates body growth.
Volume: 9
Issue: 8
Pages: 1150-1164
Publication
First Author: Tran T
Year: 2018
Journal: PLoS One
Title: GDF15 deficiency promotes high fat diet-induced obesity in mice.
Volume: 13
Issue: 8
Pages: e0201584
Publication
First Author: Ray N
Year: 2023
Journal: Commun Biol
Title: Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming.
Volume: 6
Issue: 1
Pages: 602
Publication
First Author: Chung HK
Year: 2017
Journal: Sci Rep
Title: GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury.
Volume: 7
Issue: 1
Pages: 17238
Publication
First Author: Lu JF
Year: 2023
Journal: Cell Metab
Title: GDF15 is a major determinant of ketogenic diet-induced weight loss.
Volume: 35
Issue: 12
Pages: 2165-2182.e7
Publication
First Author: Aguilar-Recarte D
Year: 2021
Journal: Cell Rep
Title: GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.
Volume: 36
Issue: 6
Pages: 109501
Publication
First Author: Campderrós L
Year: 2019
Journal: Obesity (Silver Spring)
Title: Brown Adipocytes Secrete GDF15 in Response to Thermogenic Activation.
Volume: 27
Issue: 10
Pages: 1606-1616
Publication
First Author: Lu JF
Year: 2022
Journal: PLoS Biol
Title: Camptothecin effectively treats obesity in mice through GDF15 induction.
Volume: 20
Issue: 2
Pages: e3001517
Publication
First Author: Wang D
Year: 2023
Journal: Nature
Title: GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Volume: 619
Issue: 7968
Pages: 143-150
Publication
First Author: Xie B
Year: 2022
Journal: iScience
Title: Hepatocyte-derived GDF15 suppresses feeding and improves insulin sensitivity in obese mice.
Volume: 25
Issue: 12
Pages: 105569
Publication
First Author: Klein AB
Year: 2021
Journal: Nat Commun
Title: Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise.
Volume: 12
Issue: 1
Pages: 1041
Publication
First Author: Ost M
Year: 2020
Journal: EMBO Rep
Title: Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress.
Volume: 21
Issue: 3
Pages: e48804
Publication
First Author: Fejzo M
Year: 2024
Journal: Nature
Title: GDF15 linked to maternal risk of nausea and vomiting during pregnancy.
Volume: 625
Issue: 7996
Pages: 760-767
Publication
First Author: Hao S
Year: 2019
Journal: Blood Adv
Title: Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche.
Volume: 3
Issue: 14
Pages: 2205-2217
Publication
First Author: Zeng YT
Year: 2023
Journal: iScience
Title: GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation.
Volume: 26
Issue: 10
Pages: 107902
Publication
First Author: Coll AP
Year: 2020
Journal: Nature
Title: GDF15 mediates the effects of metformin on body weight and energy balance.
Volume: 578
Issue: 7795
Pages: 444-448
Publication
First Author: Wang D
Year: 2024
Journal: Diabetes
Title: Fatty Acids Increase GDF15 and Reduce Food Intake Through a GFRAL Signaling Axis.
Volume: 73
Issue: 1
Pages: 51-56
Publication  
First Author: Jurado-Aguilar J
Year: 2024
Journal: Metabolism
Title: GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway.
Volume: 152
Pages: 155772
Publication
First Author: Gil CI
Year: 2019
Journal: Sci Rep
Title: Role of GDF15 in active lifestyle induced metabolic adaptations and acute exercise response in mice.
Volume: 9
Issue: 1
Pages: 20120
Publication
First Author: Kang SG
Year: 2021
Journal: iScience
Title: Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response.
Volume: 24
Issue: 3
Pages: 102181
Publication
First Author: Katsumura S
Year: 2022
Journal: Cell Metab
Title: Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.
Volume: 34
Issue: 4
Pages: 564-580.e8
Publication
First Author: Breit SN
Year: 2023
Journal: Cell Metab
Title: GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
Volume: 35
Issue: 8
Pages: 1341-1355.e3
Publication
First Author: Liu J
Year: 2020
Journal: J Am Soc Nephrol
Title: Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury.
Volume: 31
Issue: 4
Pages: 701-715
Publication
First Author: Sjøberg KA
Year: 2023
Journal: Cell Metab
Title: GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism.
Volume: 35
Issue: 8
Pages: 1327-1340.e5
Publication    
First Author: Worth AA
Year: 2020
Journal: Elife
Title: The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling.
Volume: 9
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190388
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gdf15
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190388
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gdf15
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190388
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gdf15
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190388
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gdf15
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190388
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gdf15
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190388
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gdf15
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6173445
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190388
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gdf15
Detected: false
Specimen Num: 7
Publication
First Author: Day EA
Year: 2019
Journal: Nat Metab
Title: Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.
Volume: 1
Issue: 12
Pages: 1202-1208
Publication
First Author: Mullican SE
Year: 2017
Journal: Nat Med
Title: GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
Volume: 23
Issue: 10
Pages: 1150-1157
Publication  
First Author: Frikke-Schmidt H
Year: 2019
Journal: Mol Metab
Title: GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice.
Volume: 21
Pages: 13-21
Publication
First Author: Patel AR
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: LPS induces rapid increase in GDF15 levels in mice, rats, and humans but is not required for anorexia in mice.
Volume: 322
Issue: 2
Pages: G247-G255
Publication  
First Author: Patel S
Year: 2022
Journal: Mol Metab
Title: Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice.
Volume: 65
Pages: 101589
Publication
First Author: Low JK
Year: 2017
Journal: PLoS One
Title: First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15.
Volume: 12
Issue: 1
Pages: e0168416
Publication
First Author: Tsai VW
Year: 2013
Journal: PLoS One
Title: TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator.
Volume: 8
Issue: 2
Pages: e55174
Publication
First Author: Abulizi P
Year: 2017
Journal: Sci Rep
Title: Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide.
Volume: 7
Issue: 1
Pages: 1037
Publication
First Author: Wang X
Year: 2014
Journal: Aging (Albany NY)
Title: hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling.
Volume: 6
Issue: 8
Pages: 690-704
Publication
First Author: Husaini Y
Year: 2015
Journal: PLoS One
Title: Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice.
Volume: 10
Issue: 2
Pages: e0115189
Publication
First Author: Chrysovergis K
Year: 2014
Journal: Int J Obes (Lond)
Title: NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.
Volume: 38
Issue: 12
Pages: 1555-64
Publication  
First Author: Moschovaki-Filippidou F
Year: 2020
Journal: Int J Mol Sci
Title: Growth Differentiation Factor 15 Ameliorates Anti-Glomerular Basement Membrane Glomerulonephritis in Mice.
Volume: 21
Issue: 19
Publication
First Author: Klein AB
Year: 2022
Journal: Cell Rep
Title: The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance.
Volume: 40
Issue: 8
Pages: 111258
Publication
First Author: Zimmers TA
Year: 2006
Journal: J Surg Res
Title: Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms.
Volume: 130
Issue: 1
Pages: 45-51
Publication
First Author: Hsiao EC
Year: 2000
Journal: Mol Cell Biol
Title: Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury.
Volume: 20
Issue: 10
Pages: 3742-51
Publication
First Author: Kincaid JWR
Year: 2024
Journal: Sci Rep
Title: The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15.
Volume: 14
Issue: 1
Pages: 1899
Publication  
First Author: Jeong S
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Cell non-autonomous effect of hepatic growth differentiation factor 15 on the thyroid gland.
Volume: 13
Pages: 966644
Publication
First Author: Zimmers TA
Year: 2008
Journal: J Cancer Res Clin Oncol
Title: Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis.
Volume: 134
Issue: 7
Pages: 753-9
Publication
First Author: Hofer M
Year: 2018
Journal: Physiol Res
Title: Hematological findings in non-treated and gamma-irradiated mice deficient for MIC-1/GDF15.
Volume: 67
Issue: 4
Pages: 623-636
Publication  
First Author: Patsalos A
Year: 2022
Journal: J Exp Med
Title: A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Volume: 219
Issue: 1
Publication
First Author: Hinoi E
Year: 2012
Journal: J Bone Miner Res
Title: Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia.
Volume: 27
Issue: 4
Pages: 938-49
Publication  
First Author: Zhang M
Year: 2018
Journal: Redox Biol
Title: Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.
Volume: 16
Pages: 87-96
Publication  
First Author: Asrih M
Year: 2022
Journal: Mol Cell Endocrinol
Title: Growth differentiation factor-15 prevents glucotoxicity and connexin-36 downregulation in pancreatic beta-cells.
Volume: 541
Pages: 111503
Publication
First Author: Guillaume M
Year: 2019
Journal: Hepatol Commun
Title: Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice.
Volume: 3
Issue: 7
Pages: 908-924
Publication
First Author: Lee SE
Year: 2017
Journal: Diabetes
Title: Growth Differentiation Factor 15 Mediates Systemic Glucose Regulatory Action of T-Helper Type 2 Cytokines.
Volume: 66
Issue: 11
Pages: 2774-2788
Publication
First Author: Ito T
Year: 2018
Journal: Biol Pharm Bull
Title: Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse.
Volume: 41
Issue: 3
Pages: 435-439
Publication
First Author: Arif E
Year: 2019
Journal: Kidney Int
Title: The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes.
Volume: 96
Issue: 1
Pages: 139-158
Publication
First Author: Jung SB
Year: 2018
Journal: Nat Commun
Title: Reduced oxidative capacity in macrophages results in systemic insulin resistance.
Volume: 9
Issue: 1
Pages: 1551
Publication
First Author: Chung HK
Year: 2017
Journal: J Cell Biol
Title: Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
Volume: 216
Issue: 1
Pages: 149-165
Publication  
First Author: Xiong Y
Year: 2017
Journal: Sci Transl Med
Title: Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Volume: 9
Issue: 412
Publication
First Author: Mazagova M
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Genetic deletion of growth differentiation factor 15 augments renal damage in both type 1 and type 2 models of diabetes.
Volume: 305
Issue: 9
Pages: F1249-64
Publication
First Author: Xu J
Year: 2006
Journal: Circ Res
Title: GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation.
Volume: 98
Issue: 3
Pages: 342-50
Publication  
First Author: Zhang Y
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro: Role of Hif-1α.
Volume: 332
Pages: 8-14
Publication  
First Author: Oka M
Year: 2020
Journal: Cells
Title: New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6.
Volume: 9
Issue: 6
Publication
First Author: Widera C
Year: 2012
Journal: Clin Chem
Title: Identification of follistatin-like 1 by expression cloning as an activator of the growth differentiation factor 15 gene and a prognostic biomarker in acute coronary syndrome.
Volume: 58
Issue: 8
Pages: 1233-41
Publication
First Author: Santos I
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis.
Volume: 117
Issue: 22
Pages: 12281-12287
Publication
First Author: Kim KH
Year: 2018
Journal: Sci Rep
Title: Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.
Volume: 8
Issue: 1
Pages: 6789
Publication  
First Author: Bennett LF
Year: 2019
Journal: Sci Signal
Title: Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C.
Volume: 12
Issue: 598
Publication
First Author: Patel AR
Year: 2023
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Neither GLP-1 receptors nor GFRAL neurons are required for aversive or anorectic response to DON (vomitoxin).
Volume: 324
Issue: 5
Pages: R635-44
Publication
First Author: Mazagova M
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Growth differentiation factor 15 impairs aortic contractile and relaxing function through altered caveolar signaling of the endothelium.
Volume: 304
Issue: 5
Pages: H709-18
Publication
First Author: Hsu JY
Year: 2017
Journal: Nature
Title: Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Volume: 550
Issue: 7675
Pages: 255-259
Publication
First Author: Choi MJ
Year: 2020
Journal: Diabetologia
Title: An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Volume: 63
Issue: 4
Pages: 837-852
Publication
First Author: Myojin Y
Year: 2021
Journal: Gastroenterology
Title: Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production.
Volume: 160
Issue: 5
Pages: 1741-1754.e16
Publication
First Author: Baur K
Year: 2024
Journal: Stem Cell Reports
Title: Growth/differentiation factor 15 controls ependymal and stem cell number in the V-SVZ.
Volume: 19
Issue: 3
Pages: 351-365
Publication
First Author: Kim J
Year: 2021
Journal: Nat Metab
Title: TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response.
Volume: 3
Issue: 3
Pages: 410-427
Publication
First Author: Kim HH
Year: 2023
Journal: Exp Mol Med
Title: Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease.
Volume: 55
Issue: 1
Pages: 158-170
Publication    
First Author: Moon JS
Year: 2020
Journal: Aging Cell
Title: Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice.
Pages: e13195
Publication
First Author: Noorali S
Year: 2007
Journal: Differentiation
Title: Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse.
Volume: 75
Issue: 4
Pages: 325-36
Publication
First Author: Maschalidi S
Year: 2022
Journal: Nature
Title: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Volume: 606
Issue: 7915
Pages: 776-784
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory