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Search results 1 to 100 out of 701 for Gdf5

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
key_979935 | Gdf5
Type: gene
Organism: Not Specified
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Gene
8200 | GDF5
Type: gene
Organism: human
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Gene
100189547 | gdf5
Type: gene
Organism: frog, western clawed
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Gene
485850 | GDF5
Type: gene
Organism: dog, domestic
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Gene
252835 | Gdf5
Type: gene
Organism: rat
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Gene
458202 | GDF5
Type: gene
Organism: chimpanzee
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Gene
539559 | GDF5
Type: gene
Organism: cattle
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Gene
374249 | GDF5
Type: gene
Organism: chicken
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Gene
100334210 | gdf5
Type: gene
Organism: zebrafish
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Gene
705432 | GDF5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:95688 | Gdf5
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
109461476 | LOC109461476
Type: gene
Organism: human
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Gene
554250 | GDF5-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5446474
Age: embryonic day 12.5
Image: 2 Gdf5 12.5 wt
Note: Expression in perichondrium of early digital anlage, with a striped pattern of expression in developing joints of digits.
Specimen Label: 2 Gdf5 12.5 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5446474
Age: embryonic day 12.5
Image: 2 Gdf5 12.5 spdh/spdh
Note: No expression in phalangeal anlagen.
Specimen Label: 2 Gdf5 12.5 spdh/spdh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446491
Age: embryonic day 14.5
Image: 5 Gdf5 14.5 wt
Note: Subject: sclera & lacrimal glan
Specimen Label: 5 Gdf5 14.5 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3264522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446491
Age: embryonic day 14.5
Image: 5 Gdf5 14.5 spdh/spdh
Note: Reduced expression in perichondrium. No expression in interzone.
Specimen Label: 5 Gdf5 14.5 spdh/spdh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5446491
Age: embryonic day 16.5
Image: 5 Gdf5 16.5 wt
Note: Expression in perichondrium, joint interzone, and cartilage of joint.
Specimen Label: 5 Gdf5 16.5 wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3264524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5446491
Age: embryonic day 16.5
Image: 5 Gdf5 16.5 spdh/spdh
Note: Reduced expression in perichondrium. No expression in interzone, with the exception of digit 1 and distal interphalangeal joints.
Specimen Label: 5 Gdf5 16.5 spdh/spdh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5446474
Age: embryonic day 13.5
Image: 2 Gdf5 13.5 wt
Note: Expression in developing joints of entire autopod.
Specimen Label: 2 Gdf5 13.5 wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5446474
Age: embryonic day 13.5
Image: 2 Gdf5 13.5 spdh/spdh
Note: Some expression in joints between distal and middle phalanges, and between carpal bones. No expression in the joint interzone of digits.
Specimen Label: 2 Gdf5 13.5 spdh/spdh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3633623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1+/+
Note: Expression in proximal and distal interphalangeal joints
Specimen Label: 2C Gdf5 Slit1+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3633623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1-/- Slit2-/-
Note: Expression in proximal and distal interphalangeal joints
Specimen Label: 2C Gdf5 Slit1-/- Slit2-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5446225
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1743121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5446474
Age: embryonic day 13.5
Image: 2 Gdf5 13.5 spdh/spdh
Note: Some expression in metacarpophalangeal joint of digit 1,
Specimen Label: 2 Gdf5 13.5 spdh/spdh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1+/+
Specimen Label: 2C Gdf5 Slit1+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1-/- Slit2-/-
Specimen Label: 2C Gdf5 Slit1-/- Slit2-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3804123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1+/+
Specimen Label: 2C Gdf5 Slit1+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6780194
Assay Type: RNA in situ
Annotation Date: 2021-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3804123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6780206
Age: embryonic day 15.5
Image: 2C Gdf5 Slit1-/- Slit2-/-
Specimen Label: 2C Gdf5 Slit1-/- Slit2-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3654010
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3654459
Age: embryonic day 17.5
Image: 2
Specimen Label: GDF5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3654010
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:3654512
Age: embryonic day 11.5
Image: 2
Specimen Label: GDF5
Detected: true
Specimen Num: 2
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Publication
31932746 | J:293138
First Author: Kania K
Year: 2020
Journal: Sci Rep
Title: Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis.
Volume: 10
Issue: 1
Pages: 157
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Protein
A0A384V9W7
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: true
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Publication
23356643 | J:193467
 
First Author: Kan A
Year: 2013
Journal: BMC Dev Biol
Title: SOX11 contributes to the regulation of GDF5 in joint maintenance.
Volume: 13
Pages: 4
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Publication
31596513 | J:293213
First Author: Hagiwara Y
Year: 2020
Journal: Ann N Y Acad Sci
Title: Cells from a GDF5 origin produce zonal tendon-to-bone attachments following anterior cruciate ligament reconstruction.
Volume: 1460
Issue: 1
Pages: 57-67
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Publication
10208739 | J:54643
First Author: Storm EE
Year: 1999
Journal: Dev Biol
Title: GDF5 coordinates bone and joint formation during digit development.
Volume: 209
Issue: 1
Pages: 11-27
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Publication
24098149 | J:202818
First Author: Degenkolbe E
Year: 2013
Journal: PLoS Genet
Title: A GDF5 point mutation strikes twice--causing BDA1 and SYNS2.
Volume: 9
Issue: 10
Pages: e1003846
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Publication
27030100 | J:251646
 
First Author: Liu J
Year: 2016
Journal: Sci Rep
Title: Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.
Volume: 6
Pages: 23670
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Publication
- | J:200816
     
First Author: Karst SY
Year: 2013
Journal: MGI Direct Data Submission
Title: Brachypodism 5 Jackson, a mouse model of GDF5 genetic diseases
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Publication
30388100 | J:267710
First Author: Kiapour AM
Year: 2018
Journal: PLoS One
Title: The role of Gdf5 regulatory regions in development of hip morphology.
Volume: 13
Issue: 11
Pages: e0202785
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Publication
14613311 | J:87281
First Author: Coleman CM
Year: 2003
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Correlation of GDF5 and connexin 43 mRNA expression during embryonic development.
Volume: 275
Issue: 2
Pages: 1117-21
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GXD Expression
GXD Expression
 
Probe: MGI:3687180
Assay Type: RNA in situ
Annotation Date: 2006-11-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1763522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3687181
Age: embryonic day 14.5
Note: Expression was strong in the perichondrium.
Specimen Label: 6B Gdf5 left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3687180
Assay Type: RNA in situ
Annotation Date: 2006-11-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3687181
Age: embryonic day 14.5
Note: Expression was weak in the perichondrium.
Specimen Label: 6B Gdf5 right
Detected: true
Specimen Num: 2
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Publication
- | J:358046
   
First Author: Pregizer S
Year: 2018
Journal: Orthopedic Research Society Annual Meeting
Title: A Novel Mouse Model to Elucidate the Role of Gdf5 in Postnatal Joints
Pages: Abstract 0007
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Publication
20805298 | J:208177
First Author: Daans M
Year: 2011
Journal: Ann Rheum Dis
Title: GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes.
Volume: 70
Issue: 1
Pages: 208-13
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Publication
27902701 | J:237411
First Author: Chen H
Year: 2016
Journal: PLoS Genet
Title: Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton.
Volume: 12
Issue: 11
Pages: e1006454
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Publication
31694926 | J:294564
 
First Author: Traoré M
Year: 2019
Journal: Sci Transl Med
Title: An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse.
Volume: 11
Issue: 517
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Publication
26141957 | J:225829
First Author: Dyment NA
Year: 2015
Journal: Dev Biol
Title: Gdf5 progenitors give rise to fibrocartilage cells that mineralize via hedgehog signaling to form the zonal enthesis.
Volume: 405
Issue: 1
Pages: 96-107
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Publication
26542169 | J:310008
First Author: Howard M
Year: 2016
Journal: In Vitro Cell Dev Biol Anim
Title: The function and interrelationship between GDF5 and ERG-010 during chondrogenesis in vitro.
Volume: 52
Issue: 2
Pages: 182-92
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Publication
29311146 | J:274501
First Author: Pregizer SK
Year: 2018
Journal: Ann Rheum Dis
Title: Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis.
Volume: 77
Issue: 3
Pages: 450
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Publication
17656374 | J:125122
First Author: Masuya H
Year: 2007
Journal: Hum Mol Genet
Title: A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice.
Volume: 16
Issue: 19
Pages: 2366-75
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Publication
38836497 | J:357740
First Author: Sorsby M
Year: 2024
Journal: J Bone Miner Res
Title: The role of GDF5 in regulating enthesopathy development in the Hyp mouse model of XLH.
Volume: 39
Issue: 8
Pages: 1162-1173
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Publication
29146735 | J:259618
First Author: Hatazawa Y
Year: 2018
Journal: FASEB J
Title: Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration.
Volume: 32
Issue: 3
Pages: 1452-1467
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Publication
18363966 | J:141606
First Author: Itoh S
Year: 2008
Journal: Genes Cells
Title: Trps1 plays a pivotal role downstream of Gdf5 signaling in promoting chondrogenesis and apoptosis of ATDC5 cells.
Volume: 13
Issue: 4
Pages: 355-63
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Publication
16127465 | J:100917
First Author: Seemann P
Year: 2005
Journal: J Clin Invest
Title: Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2.
Volume: 115
Issue: 9
Pages: 2373-81
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Publication
12606286 | J:83132
First Author: Settle SH Jr
Year: 2003
Journal: Dev Biol
Title: Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes.
Volume: 254
Issue: 1
Pages: 116-30
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Publication
21976273 | J:299317
First Author: Schwaerzer GK
Year: 2012
Journal: J Bone Miner Res
Title: New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.
Volume: 27
Issue: 2
Pages: 429-42
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190391
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gdf5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190391
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gdf5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190391
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gdf5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190391
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gdf5
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190391
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gdf5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190391
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gdf5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6173449
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190391
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gdf5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5806588
Assay Type: RNA in situ
Annotation Date: 2016-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5806796
Age: embryonic day 12.5
Image: 5a,c
Note: Gdf5 and Bmpr1b are expressed in nonoverlapping, but adjacent regions of the limb.
Specimen Label: 5a,c
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:5806588
Assay Type: RNA in situ
Annotation Date: 2016-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5806796
Age: embryonic day 13.5
Image: 5d,f
Note: Gdf5 and Bmpr1b are expressed in nonoverlapping, but adjacent regions of the limb.
Specimen Label: 5d,f
Detected: true
Specimen Num: 11
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Publication
27292641 | J:234264
First Author: Shwartz Y
Year: 2016
Journal: Cell Rep
Title: Joint Development Involves a Continuous Influx of Gdf5-Positive Cells.
Volume: 15
Issue: 12
Pages: 2577-87
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Publication
15492776 | J:97780
First Author: Rountree RB
Year: 2004
Journal: PLoS Biol
Title: BMP receptor signaling is required for postnatal maintenance of articular cartilage.
Volume: 2
Issue: 11
Pages: e355
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Publication
32022343 | J:289435
First Author: Zhang Y
Year: 2020
Journal: Dev Dyn
Title: Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds.
Volume: 249
Issue: 6
Pages: 711-722
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Publication
- | J:226157
     
First Author: Harris BS
Year: 2015
Journal: MGI Direct Data Submission
Title: brachypodism 6 Jackson
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Publication
17085896 | J:124813
First Author: Suto J
Year: 2006
Journal: J Vet Med Sci
Title: Identification of mutation in the growth differentiation factor 5 (Gdf5) gene in NC-brp/brp mice.
Volume: 68
Issue: 10
Pages: 1121-4
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Publication
29665134 | J:264602
First Author: Gamer LW
Year: 2018
Journal: J Bone Miner Res
Title: The Role of Bmp2 in the Maturation and Maintenance of the Murine Knee Joint.
Volume: 33
Issue: 9
Pages: 1708-1717
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Publication
20206616 | J:160493
First Author: Dy P
Year: 2010
Journal: Dev Biol
Title: Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.
Volume: 341
Issue: 2
Pages: 346-59
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Publication
15542031 | J:94510
First Author: Takahara M
Year: 2004
Journal: Bone
Title: Developmental failure of phalanges in the absence of growth/differentiation factor 5.
Volume: 35
Issue: 5
Pages: 1069-76
•
•
•
•
•
Publication
26878848 | J:229534
 
First Author: O'Keeffe GW
Year: 2016
Journal: Neural Dev
Title: Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation.
Volume: 11
Pages: 4
•
•
•
•
•
Publication
20117381 | J:309053
First Author: Zaidi SH
Year: 2010
Journal: J Am Coll Cardiol
Title: Growth differentiation factor 5 regulates cardiac repair after myocardial infarction.
Volume: 55
Issue: 2
Pages: 135-43
•
•
•
•
•
Publication
24173804 | J:205042
First Author: Osório C
Year: 2013
Journal: Development
Title: Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development.
Volume: 140
Issue: 23
Pages: 4751-62
•
•
•
•
•
Publication
9012517 | J:38423
First Author: Storm EE
Year: 1996
Journal: Development
Title: Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family.
Volume: 122
Issue: 12
Pages: 3969-79
•
•
•
•
•
Publication
24062245 | J:208918
First Author: Hinoi E
Year: 2014
Journal: Diabetes
Title: Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure.
Volume: 63
Issue: 1
Pages: 162-75
•
•
•
•
•
Publication
8145850 | J:17582
First Author: Storm EE
Year: 1994
Journal: Nature
Title: Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.
Volume: 368
Issue: 6472
Pages: 639-43
•
•
•
•
•
Publication
20034107 | J:156949
First Author: Perez WD
Year: 2010
Journal: Dev Dyn
Title: Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development.
Volume: 239
Issue: 2
Pages: 446-57
•
•
•
•
•
Publication
35608281 | J:326033
 
First Author: Kim M
Year: 2022
Journal: Biol Open
Title: Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs.
Volume: 11
Issue: 6
•
•
•
•
•
Publication
25223801 | J:220087
First Author: Hinoi E
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Nuclear factor-κB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate.
Volume: 452
Issue: 4
Pages: 974-9
•
•
•
•
•
Publication
26483211 | J:227705
First Author: Macpherson PC
Year: 2015
Journal: Development
Title: Dach2-Hdac9 signaling regulates reinnervation of muscle endplates.
Volume: 142
Issue: 23
Pages: 4038-48
•
•
•
•
•
Publication
24944017 | J:219431
First Author: Hinoi E
Year: 2014
Journal: Biochem Biophys Res Commun
Title: PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway.
Volume: 450
Issue: 1
Pages: 255-60
•
•
•
•
•
Publication
15800003 | J:98500
First Author: Meech R
Year: 2005
Journal: Development
Title: The homeobox transcription factor Barx2 regulates chondrogenesis during limb development.
Volume: 132
Issue: 9
Pages: 2135-46
•
•
•
•
•
Publication
22365545 | J:182705
First Author: Choe Y
Year: 2012
Journal: Neuron
Title: A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation.
Volume: 73
Issue: 4
Pages: 698-712
•
•
•
•
•
Publication
38472182 | J:346064
First Author: Leung AOW
Year: 2024
Journal: Nat Commun
Title: Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1.
Volume: 15
Issue: 1
Pages: 2229
•
•
•
•
•
Publication
10631182 | J:59282
First Author: Yi SE
Year: 2000
Journal: Development
Title: The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb.
Volume: 127
Issue: 3
Pages: 621-30
•
•
•
•
•
Publication
18353862 | J:134490
First Author: Raz R
Year: 2008
Journal: Development
Title: The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome.
Volume: 135
Issue: 9
Pages: 1713-23
•
•
•
•
•
Publication
16962305 | J:113431
First Author: Tavella S
Year: 2006
Journal: Matrix Biol
Title: Forced chondrocyte expression of sonic hedgehog impairs joint formation affecting proliferation and apoptosis.
Volume: 25
Issue: 7
Pages: 389-97
•
•
•
•
•
Publication
18083924 | J:133905
 
First Author: Koyama E
Year: 2007
Journal: Ann N Y Acad Sci
Title: Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling.
Volume: 1116
Pages: 100-12
•
•
•
•
•
Publication
35503090 | J:324217
   
First Author: Mead TJ
Year: 2022
Journal: Elife
Title: Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.
Volume: 11
•
•
•
•
•
Publication
28169396 | J:241783
First Author: Tang L
Year: 2017
Journal: Hum Mol Genet
Title: A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.
Volume: 26
Issue: 7
Pages: 1280-1293
•
•
•
•
•
Publication
26097038 | J:243715
First Author: Ohta Y
Year: 2015
Journal: Arthritis Rheumatol
Title: Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.
Volume: 67
Issue: 10
Pages: 2679-90
•
•
•
•
•
Publication
10631181 | J:59288
First Author: Baur ST
Year: 2000
Journal: Development
Title: Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity.
Volume: 127
Issue: 3
Pages: 605-19
•
•
•
•
•
Publication
21185280 | J:170582
First Author: Mundy C
Year: 2011
Journal: Dev Biol
Title: Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine.
Volume: 351
Issue: 1
Pages: 70-81
•
•
•
•
•
Publication
14973294 | J:88584
First Author: Tucker AS
Year: 2004
Journal: Development
Title: Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution.
Volume: 131
Issue: 6
Pages: 1235-45
•
•
•
•
•
Publication
25926361 | J:221660
First Author: Eyal S
Year: 2015
Journal: Development
Title: On the development of the patella.
Volume: 142
Issue: 10
Pages: 1831-9
•
•
•
•
•
Publication
19460349 | J:148688
First Author: Kahn J
Year: 2009
Journal: Dev Cell
Title: Muscle contraction is necessary to maintain joint progenitor cell fate.
Volume: 16
Issue: 5
Pages: 734-43
•
•
•
•
•
Publication
11476582 | J:71186
First Author: Chiang C
Year: 2001
Journal: Dev Biol
Title: Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function.
Volume: 236
Issue: 2
Pages: 421-35
•
•
•
•
•




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