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Search results 1 to 100 out of 1461 for Gdnf

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Type Details Score
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: This group represents glial cell line-derived neurotrophic factor (GDNF). This is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake [, ]. Defects in GDNF are a cause of congenital central hypoventilation syndrome (also known as Ondine's curse) and are also linked with Hirschsprung disease [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:1201618
Assay Type: RNA in situ
Annotation Date: 2020-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3544421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6386327
Age: embryonic day 13.0
Image: 5 GDNF
Note: Expression is in the mucosal epithelium.
Specimen Label: 5 GDNF
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1201618
Assay Type: RNA in situ
Annotation Date: 2020-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6386327
Age: embryonic day 13.0
Image: 5 GDNF
Specimen Label: 5 GDNF
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1201618
Assay Type: RNA in situ
Annotation Date: 2020-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3643721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6386327
Age: embryonic day 13.0
Image: 5 GDNF
Specimen Label: 5 GDNF
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1201618
Assay Type: RNA in situ
Annotation Date: 2020-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6386327
Age: postnatal newborn
Image: 7 gdnf
Specimen Label: 7 gdnf
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:2664233
Assay Type: RNA in situ
Annotation Date: 2003-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2665169
Age: embryonic day 11.5
Image: Q Gdnf
Specimen Label: Q Gdnf
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2664233
Assay Type: RNA in situ
Annotation Date: 2003-07-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737519
Stage: TS19
Assay Id: MGI:2665169
Age: embryonic day 11.5
Image: R Gdnf
Specimen Label: R Gdnf
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:1201618
Assay Type: RNA in situ
Annotation Date: 2020-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6386327
Age: embryonic day 13.0
Image: 5 GDNF
Specimen Label: 5 GDNF
Detected: true
Specimen Num: 1
Publication
First Author: Lin LF
Year: 1993
Journal: Science
Title: GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.
Volume: 260
Issue: 5111
Pages: 1130-2
Protein
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
Publication
First Author: Haniu M
Year: 1996
Journal: Biochemistry
Title: Glial cell line-derived neurotrophic factor: selective reduction of the intermolecular disulfide linkage and characterization of its disulfide structure.
Volume: 35
Issue: 51
Pages: 16799-805
Publication
First Author: Amiel J
Year: 1998
Journal: Am J Hum Genet
Title: Mutations of the RET-GDNF signaling pathway in Ondine's curse.
Volume: 62
Issue: 3
Pages: 715-7
Publication
First Author: Hofstra RM
Year: 1997
Journal: Eur J Hum Genet
Title: Mutations in Hirschsprung disease: when does a mutation contribute to the phenotype.
Volume: 5
Issue: 4
Pages: 180-5
Gene
Type: gene
Organism: human
Publication
First Author: Glerup S
Year: 2013
Journal: Cell Rep
Title: SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Volume: 3
Issue: 1
Pages: 186-99
Publication
First Author: Baloh RH
Year: 1997
Journal: Neuron
Title: TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.
Volume: 18
Issue: 5
Pages: 793-802
Publication
First Author: Pascual A
Year: 2008
Journal: Nat Neurosci
Title: Absolute requirement of GDNF for adult catecholaminergic neuron survival.
Volume: 11
Issue: 7
Pages: 755-61
Publication
First Author: Muñoz-Bravo JL
Year: 2013
Journal: Development
Title: GDNF is required for neural colonization of the pancreas.
Volume: 140
Issue: 17
Pages: 3669-79
Publication  
First Author: Sharma M
Year: 2018
Journal: Development
Title: Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis.
Volume: 145
Issue: 5
Publication
First Author: Enterría-Morales D
Year: 2016
Journal: PLoS One
Title: Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse.
Volume: 11
Issue: 10
Pages: e0164391
Publication
First Author: Gerlai R
Year: 2001
Journal: Eur J Neurosci
Title: Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation.
Volume: 14
Issue: 7
Pages: 1153-63
Publication
First Author: Shakya R
Year: 2005
Journal: Dev Biol
Title: The role of GDNF in patterning the excretory system.
Volume: 283
Issue: 1
Pages: 70-84
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
Publication
First Author: Gianino S
Year: 2003
Journal: Development
Title: GDNF availability determines enteric neuron number by controlling precursor proliferation.
Volume: 130
Issue: 10
Pages: 2187-98
Protein
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
Publication
First Author: Young HM
Year: 2001
Journal: Dev Biol
Title: GDNF is a chemoattractant for enteric neural cells.
Volume: 229
Issue: 2
Pages: 503-16
Publication
First Author: Milbrandt J
Year: 1998
Journal: Neuron
Title: Persephin, a novel neurotrophic factor related to GDNF and neurturin.
Volume: 20
Issue: 2
Pages: 245-53
Publication
First Author: Naveilhan P
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Expression and regulation of GFRalpha3, a glial cell line-derived neurotrophic factor family receptor.
Volume: 95
Issue: 3
Pages: 1295-300
Publication
First Author: Enomoto H
Year: 2000
Journal: Development
Title: Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin.
Volume: 127
Issue: 22
Pages: 4877-89
Publication
First Author: Xiao N
Year: 2014
Journal: J Clin Invest
Title: Neurotrophic factor GDNF promotes survival of salivary stem cells.
Volume: 124
Issue: 8
Pages: 3364-77
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Littrell OM
Year: 2012
Journal: Neurobiol Aging
Title: Enhanced dopamine transporter activity in middle-aged Gdnf heterozygous mice.
Volume: 33
Issue: 2
Pages: 427.e1-14
Publication
First Author: Ola R
Year: 2011
Journal: J Am Soc Nephrol
Title: The GDNF target Vsnl1 marks the ureteric tip.
Volume: 22
Issue: 2
Pages: 274-84
Publication
First Author: Haase G
Year: 2002
Journal: Neuron
Title: GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor neuron pools.
Volume: 35
Issue: 5
Pages: 893-905
Publication
First Author: Hidalgo-Figueroa M
Year: 2012
Journal: J Neurosci
Title: GDNF is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after injury of the nigrostriatal pathway.
Volume: 32
Issue: 3
Pages: 864-72
Publication
First Author: Baloh RH
Year: 2000
Journal: Curr Opin Neurobiol
Title: The GDNF family ligands and receptors - implications for neural development.
Volume: 10
Issue: 1
Pages: 103-10
Publication
First Author: Uesaka T
Year: 2013
Journal: J Neurosci
Title: GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors.
Volume: 33
Issue: 41
Pages: 16372-82
Publication
First Author: Kopra J
Year: 2015
Journal: Nat Neurosci
Title: GDNF is not required for catecholaminergic neuron survival in vivo.
Volume: 18
Issue: 3
Pages: 319-22
Publication
First Author: Airaksinen MS
Year: 2002
Journal: Nat Rev Neurosci
Title: The GDNF family: signalling, biological functions and therapeutic value.
Volume: 3
Issue: 5
Pages: 383-94
Publication
First Author: Linton JM
Year: 2007
Journal: Development
Title: The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.
Volume: 134
Issue: 13
Pages: 2501-9
Publication
First Author: Cullen-McEwen LA
Year: 2003
Journal: Hypertension
Title: Nephron number, renal function, and arterial pressure in aged GDNF heterozygous mice.
Volume: 41
Issue: 2
Pages: 335-40
Publication      
First Author: Harasztosi C
Year: 2019
Journal: J Neurosci Res
Title: Differential deletion of GDNF in the auditory system leads to altered sound responsiveness.
Publication
First Author: Bonafina A
Year: 2019
Journal: Cell Rep
Title: GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons.
Volume: 29
Issue: 13
Pages: 4308-4319.e4
Publication  
First Author: Ortega-de San Luis C
Year: 2016
Journal: Front Neuroanat
Title: Simultaneous Detection of Both GDNF and GFRα1 Expression Patterns in the Mouse Central Nervous System.
Volume: 10
Pages: 73
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190395
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gdnf
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190395
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gdnf
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190395
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gdnf
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190395
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gdnf
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190395
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gdnf
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190395
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gdnf
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6173457
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190395
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gdnf
Detected: true
Specimen Num: 7
Publication
First Author: Pozas E
Year: 2005
Journal: Neuron
Title: GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons.
Volume: 45
Issue: 5
Pages: 701-13
Publication
First Author: Charoy C
Year: 2012
Journal: Neuron
Title: gdnf activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance.
Volume: 75
Issue: 6
Pages: 1051-66
Publication
First Author: Boger HA
Year: 2009
Journal: Neurobiol Dis
Title: Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice.
Volume: 33
Issue: 3
Pages: 459-66
Publication
First Author: Pepicelli CV
Year: 1997
Journal: Dev Biol
Title: GDNF induces branching and increased cell proliferation in the ureter of the mouse.
Volume: 192
Issue: 1
Pages: 193-8
Publication
First Author: Sergaki MC
Year: 2017
Journal: Cell Rep
Title: Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning.
Volume: 19
Issue: 10
Pages: 1977-1986
Publication
First Author: Ai X
Year: 2007
Journal: Development
Title: SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.
Volume: 134
Issue: 18
Pages: 3327-38
Protein
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
Publication
First Author: Angka HE
Year: 2008
Journal: Dev Dyn
Title: Differential survival response of neurons to exogenous GDNF depends on the presence of skeletal muscle.
Volume: 237
Issue: 11
Pages: 3169-78
Publication
First Author: Michos O
Year: 2010
Journal: PLoS Genet
Title: Kidney development in the absence of Gdnf and Spry1 requires Fgf10.
Volume: 6
Issue: 1
Pages: e1000809
Publication
First Author: Chen LY
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Targeting the Gdnf Gene in peritubular myoid cells disrupts undifferentiated spermatogonial cell development.
Volume: 113
Issue: 7
Pages: 1829-34
Publication
First Author: Airavaara M
Year: 2004
Journal: Eur J Neurosci
Title: Increased extracellular dopamine concentrations and FosB/DeltaFosB expression in striatal brain areas of heterozygous GDNF knockout mice.
Volume: 20
Issue: 9
Pages: 2336-44
Publication
First Author: Farrand AQ
Year: 2015
Journal: Neurobiol Aging
Title: Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice.
Volume: 36
Issue: 3
Pages: 1569-76
Publication  
First Author: Hadaczek P
Year: 2015
Journal: Exp Neurol
Title: GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.
Volume: 263
Pages: 177-89
Publication
First Author: Mätlik K
Year: 2018
Journal: Sci Rep
Title: Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects.
Volume: 8
Issue: 1
Pages: 11861
Publication
First Author: Uchida A
Year: 2016
Journal: Biochem Biophys Res Commun
Title: In vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay.
Volume: 476
Issue: 4
Pages: 546-552
Publication
First Author: Jin L
Year: 2022
Journal: Cell Death Dis
Title: Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling.
Volume: 13
Issue: 9
Pages: 759
Publication
First Author: Brodbeck S
Year: 2004
Journal: Mech Dev
Title: The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter.
Volume: 121
Issue: 10
Pages: 1211-22
Publication
First Author: Paratcha G
Year: 2006
Journal: Mol Cell Neurosci
Title: GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream.
Volume: 31
Issue: 3
Pages: 505-14
Publication
First Author: Shen L
Year: 2002
Journal: Am J Hum Genet
Title: Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice.
Volume: 70
Issue: 2
Pages: 435-47
Publication
First Author: Flynn B
Year: 2007
Journal: Dev Dyn
Title: Effect of Gdnf haploinsufficiency on rate of migration and number of enteric neural crest-derived cells.
Volume: 236
Issue: 1
Pages: 134-41
Publication
First Author: Anitha M
Year: 2006
Journal: J Clin Invest
Title: GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway.
Volume: 116
Issue: 2
Pages: 344-56
Publication  
First Author: Shneider NA
Year: 2009
Journal: Neural Dev
Title: Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival.
Volume: 4
Pages: 42
Publication
First Author: Arce V
Year: 1998
Journal: J Neurosci
Title: Synergistic effects of schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1).
Volume: 18
Issue: 4
Pages: 1440-8
Publication
First Author: Basson MA
Year: 2006
Journal: Dev Biol
Title: Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1.
Volume: 299
Issue: 2
Pages: 466-77
Publication
First Author: Callahan T
Year: 2008
Journal: Glia
Title: Development of satellite glia in mouse sympathetic ganglia: GDNF and GFR alpha 1 are not essential.
Volume: 56
Issue: 13
Pages: 1428-37
Publication
First Author: Golden JP
Year: 1999
Journal: Exp Neurol
Title: Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse.
Volume: 158
Issue: 2
Pages: 504-28
Publication
First Author: Kumar A
Year: 2015
Journal: PLoS Genet
Title: GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function.
Volume: 11
Issue: 12
Pages: e1005710
Publication
First Author: Griffin WC 3rd
Year: 2006
Journal: Brain Res
Title: Partial deletion of glial cell line-derived neurotrophic factor (GDNF) in mice: Effects on sucrose reward and striatal GDNF concentrations.
Volume: 1068
Issue: 1
Pages: 257-60
Publication
First Author: Zhang N
Year: 2020
Journal: Glia
Title: GLAST-CreERT2 mediated deletion of GDNF increases brain damage and exacerbates long-term stroke outcomes after focal ischemic stroke in mouse model.
Volume: 68
Issue: 11
Pages: 2395-2414
Publication
First Author: Rosenthal A
Year: 1999
Journal: Neuron
Title: The GDNF protein family: gene ablation studies reveal what they really do and how.
Volume: 22
Issue: 2
Pages: 201-3
Publication
First Author: Hanbury R
Year: 2003
Journal: J Comp Neurol
Title: GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.
Volume: 461
Issue: 3
Pages: 307-16
Publication
First Author: Boger HA
Year: 2006
Journal: Exp Neurol
Title: A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra.
Volume: 202
Issue: 2
Pages: 336-47
Publication  
First Author: Chermenina M
Year: 2014
Journal: Neuroscience
Title: GDNF is important for striatal organization and maintenance of dopamine neurons grown in the presence of the striatum.
Volume: 270
Pages: 1-11
Gene
Type: gene
Organism: human
Publication
First Author: Li L
Year: 2019
Journal: Nat Metab
Title: Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice.
Volume: 1
Issue: 10
Pages: 985-995
Publication
First Author: Luukko K
Year: 1997
Journal: Dev Dyn
Title: Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis.
Volume: 210
Issue: 4
Pages: 463-71