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Search results 1 to 82 out of 82 for Gemin4

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
50628 | GEMIN4
Type: gene
Organism: human
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Gene
100379790 | gemin4
Type: gene
Organism: frog, western clawed
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Gene
497958 | Gemin4
Type: gene
Organism: rat
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Gene
611189 | GEMIN4
Type: gene
Organism: dog, domestic
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Gene
454403 | GEMIN4
Type: gene
Organism: chimpanzee
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Gene
539147 | GEMIN4
Type: gene
Organism: cattle
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Gene
427835 | GEMIN4
Type: gene
Organism: chicken
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Gene
324754 | gemin4
Type: gene
Organism: zebrafish
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Gene
699841 | GEMIN4
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033265 | GEMIN4
Type: Family
Description: Gemin4 is one of the core components of the SMN complex, which contains survival motor neuron (SMN), the seven Gemin proteins (Gemin2-8), and Unrip. The complex is closely associated with the splicing small nuclear ribonucleoproteins (U snRNPs), which are the subunits of the spliceosome and consist of a U snRNA, the Sm core proteins and several proteins unique to the various RNPs []. SMN and Gemin4 both interact specifically with the U snRNA and the Sm core proteins, suggesting they facilitate the assembly by forming a bridge between the two components [, , ].The Gemin4 protein has also been referred to an important molecule in the RNA-induced silencing complex (RISC) that participates in the mature process of miRNAs [].
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Protein Coding Gene
MGI:2449313 | Gemin4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10725331 | J:230395
First Author: Charroux B
Year: 2000
Journal: J Cell Biol
Title: Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli.
Volume: 148
Issue: 6
Pages: 1177-86
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Protein
Q6P6L6
Organism: Mus musculus/domesticus
Length: 1058  
Fragment?: false
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Protein
Q8K1K1
Organism: Mus musculus/domesticus
Length: 1058  
Fragment?: false
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Protein
Q3URX8
Organism: Mus musculus/domesticus
Length: 1058  
Fragment?: false
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Publication
12192051 | -
First Author: Massenet S
Year: 2002
Journal: Mol Cell Biol
Title: The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway.
Volume: 22
Issue: 18
Pages: 6533-41
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Publication
14970384 | -
First Author: Nelson PT
Year: 2004
Journal: RNA
Title: miRNP:mRNA association in polyribosomes in a human neuronal cell line.
Volume: 10
Issue: 3
Pages: 387-94
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Publication
11331595 | -
First Author: Meister G
Year: 2001
Journal: EMBO J
Title: SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.
Volume: 20
Issue: 9
Pages: 2304-14
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Publication
29371219 | J:256720
 
First Author: Meier ID
Year: 2018
Journal: Biol Open
Title: Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm.
Volume: 7
Issue: 2
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Publication
18984161 | -
First Author: Chari A
Year: 2008
Journal: Cell
Title: An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.
Volume: 135
Issue: 3
Pages: 497-509
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Protein Coding Gene
MGP_CAROLIEiJ_G0016756 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2449313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017893 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017599 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:3653752
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3653752
Age: postnatal day 3
Specimen Label: 3d
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 2
Specimen Label: 2w
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 3
Specimen Label: 3w
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 30
Specimen Label: 30w
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 60
Specimen Label: 60w
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3653752
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3653752
Age: postnatal day 3
Specimen Label: 3d
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 2
Specimen Label: 2w
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 3
Specimen Label: 3w
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 30
Specimen Label: 30w
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3653738
Assay Type: Western blot
Annotation Date: 2006-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3653752
Age: postnatal week 60
Specimen Label: 60w
Detected: true
Specimen Num: 12
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Publication
- | J:77700
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone IMAGE: 3483507, mRNA, partial cds
Pages: BC005604
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Publication
16236758 | J:106808
First Author: Gabanella F
Year: 2005
Journal: Hum Mol Genet
Title: The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.
Volume: 14
Issue: 23
Pages: 3629-42
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Publication
34974536 | J:319558
     
First Author: Bizen N
Year: 2022
Journal: Cell Death Differ
Title: Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression.
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0081263 | neurodevelopmental disorder with microcephaly, cataracts, and renal abnormalities
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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