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Search results 1 to 76 out of 76 for Ggn

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Hits by Category

Hits by Strain

Type Details Score
Gene
199720 | GGN
Type: gene
Organism: human
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Gene
107966430 | GGN
Type: gene
Organism: chimpanzee
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Gene
292765 | Ggn
Type: gene
Organism: rat
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Gene
612577 | GGN
Type: gene
Organism: dog, domestic
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Gene
100140305 | GGN
Type: gene
Organism: cattle
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Gene
715072 | GGN
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2181461 | Ggn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR031400 | GGN
Type: Family
Description: Gametogenetin (GGN) is a family of proteins largely found in vertebrates. GGN reacts with POG in the maturation of sperm []and is expressed virtually only in the testis. It is also expressed in lower levels in the oocyte and is required for the survival of pre-implantation embryos []. GGN plays a role in male meiotic DNA double strand break repair []. It is found to be associated with the intracellularmembrane, binds with GGNBP1 and may be involved in vesicular trafficking [].
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Publication
23451117 | J:199404
First Author: Jamsai D
Year: 2013
Journal: PLoS One
Title: Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.
Volume: 8
Issue: 2
Pages: e56955
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Publication
12574169 | J:84438
First Author: Lu B
Year: 2003
Journal: J Biol Chem
Title: Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis.
Volume: 278
Issue: 18
Pages: 16289-96
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Publication
15642376 | J:96180
First Author: Zhang J
Year: 2005
Journal: FEBS Lett
Title: Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.
Volume: 579
Issue: 2
Pages: 559-66
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Protein
Q80WJ1
Organism: Mus musculus/domesticus
Length: 673  
Fragment?: false
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Protein
A0A140LI02
Organism: Mus musculus/domesticus
Length: 686  
Fragment?: false
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Protein
A0A140LI42
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
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Protein
G5E8M4
Organism: Mus musculus/domesticus
Length: 709  
Fragment?: false
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Publication
30055035 | J:278492
First Author: Guo K
Year: 2018
Journal: J Cell Mol Med
Title: Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice.
Volume: 22
Issue: 10
Pages: 4863-4874
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Protein Coding Gene
MGP_CAROLIEiJ_G0029475 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031884 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031678 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2181461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031753 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031122 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012709 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030571 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
14982849 | J:88438
First Author: Hansson AS
Year: 2004
Journal: Am J Pathol
Title: Relapsing polychondritis, induced in mice with matrilin 1, is an antibody- and complement-dependent disease.
Volume: 164
Issue: 3
Pages: 959-66
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:5638912
Age: postnatal adult
Image: 2
Specimen Label: Oocyte
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5638912
Age: embryonic day 1.0
Image: 2
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5638913
Age: postnatal week 10
Image: 2
Specimen Label: Testis
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5638913
Age: postnatal week 10
Image: 2
Specimen Label: Ovary
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5638913
Age: postnatal week 10
Image: 2
Specimen Label: Kidney
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5638913
Age: postnatal week 10
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5638913
Age: postnatal week 10
Image: 2
Specimen Label: Eye
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5639085
Age: postnatal week 10
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5639085
Age: postnatal week 10
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5639087
Assay Type: Western blot
Annotation Date: 2015-06-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5639088
Age: postnatal
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5639087
Assay Type: Western blot
Annotation Date: 2015-06-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5639088
Age: postnatal
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5638912
Age: embryonic day 3.0
Image: 2
Specimen Label: Morula
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5638910
Assay Type: RT-PCR
Annotation Date: 2015-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5638912
Age: embryonic day 3.5
Image: 2
Specimen Label: Blastocyst
Detected: true
Specimen Num: 4
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Publication
18502891 | J:137028
First Author: Jamsai D
Year: 2008
Journal: Reproduction
Title: Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail.
Volume: 135
Issue: 6
Pages: 751-9
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
32870280 | J:296382
First Author: Maltby CJ
Year: 2020
Journal: Nucleic Acids Res
Title: A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation.
Volume: 48
Issue: 17
Pages: 9822-9839
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SO Term
SO:0001443 | glycine
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Interaction Experiment
Jamsai D (2013)
Description: Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.
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DO Term
DOID:0070568 | spermatogenic failure 69
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Publication
38741708 | J:351993
First Author: Bugide S
Year: 2024
Journal: iScience
Title: ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models.
Volume: 27
Issue: 5
Pages: 109800
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Publication
16436378 | J:110588
First Author: Knapp AM
Year: 2006
Journal: J Biol Chem
Title: Nucleoprotein interactions governing cell type-dependent repression of the mouse smooth muscle alpha-actin promoter by single-stranded DNA-binding proteins Pur alpha and Pur beta.
Volume: 281
Issue: 12
Pages: 7907-18
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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