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Search results 1 to 100 out of 354 for Ggt1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Tsuji T
Year: 2009
Journal: Mamm Genome
Title: Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.
Volume: 20
Issue: 11-12
Pages: 711-9
Allele
Name: transgene insertion 1, Petra Pennekamp
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion M3, Eric G Neilson
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: transgenic, mutant stock
Genotype
Symbol: Tg(Ggt1-cre)M3Egn/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Ggt1-cre)M3Egn/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Koraishy FM
Year: 2014
Journal: J Biol Chem
Title: Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling.
Volume: 289
Issue: 20
Pages: 14341-50
Strain
Attribute String: congenic, mutant strain, transgenic, targeted mutation
Publication
First Author: Zhang MZ
Year: 2011
Journal: J Clin Invest
Title: Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
Volume: 121
Issue: 7
Pages: 2845-54
Publication
First Author: Chen J
Year: 2012
Journal: Kidney Int
Title: Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury.
Volume: 82
Issue: 1
Pages: 45-52
Publication
First Author: Inoue T
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Cellular communication network factor 2 (CCN2) promotes the progression of acute kidney injury to chronic kidney disease.
Volume: 517
Issue: 1
Pages: 96-102
Publication
First Author: Ge Y
Year: 2011
Journal: Lab Invest
Title: Conditional ablation of glycogen synthase kinase 3β in postnatal mouse kidney.
Volume: 91
Issue: 1
Pages: 85-96
Publication
First Author: Howard C
Year: 2012
Journal: Kidney Int
Title: Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice.
Volume: 82
Issue: 9
Pages: 1000-9
Genotype
Symbol: Ddc/Ddc Tg(Ggt1-cre)M3Egn/?
Background: 129.Cg-Ddc Tg(Ggt1-cre)M3Egn
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ddc/Ddc Tg(Ggt1-cre)M3Egn/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gsk3b/Gsk3b Tg(Ggt1-cre)M3Egn/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Twist1/Twist1 Tg(Ggt1-cre)M3Egn/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sugimoto H
Year: 2012
Journal: Nat Med
Title: Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis.
Volume: 18
Issue: 3
Pages: 396-404
Publication
First Author: Tampe B
Year: 2018
Journal: J Clin Invest
Title: Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure.
Volume: 128
Issue: 7
Pages: 3053-3070
Publication  
First Author: Li Y
Year: 2018
Journal: JCI Insight
Title: Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.
Volume: 3
Issue: 10
Publication
First Author: Hasegawa K
Year: 2013
Journal: Nat Med
Title: Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes.
Volume: 19
Issue: 11
Pages: 1496-504
Publication
First Author: Sörensen-Zender I
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury.
Volume: 306
Issue: 8
Pages: F907-15
Publication
First Author: Inoue T
Year: 2012
Journal: Kidney Int
Title: Targeted expression of a pan-caspase inhibitor in tubular epithelium attenuates interstitial inflammation and fibrogenesis in nephritic but not nephrotic mice.
Volume: 82
Issue: 9
Pages: 980-9
Publication
First Author: Guo JK
Year: 2013
Journal: Kidney Int
Title: The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages.
Volume: 84
Issue: 5
Pages: 1041-6
Genotype
Symbol: Snai1/Snai1 Tg(Ggt1-cre)M3Egn/?
Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Kimura K
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
Volume: 295
Issue: 4
Pages: F1023-9
Publication
First Author: Wu H
Year: 2016
Journal: J Am Soc Nephrol
Title: Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney Growth.
Volume: 27
Issue: 4
Pages: 1145-58
Publication  
First Author: Zhou T
Year: 2018
Journal: EBioMedicine
Title: Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ.
Volume: 31
Pages: 217-225
Publication
First Author: Muraoka H
Year: 2019
Journal: Cell Rep
Title: Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy.
Volume: 27
Issue: 1
Pages: 199-212.e5
Publication
First Author: Nlandu-Khodo S
Year: 2017
Journal: J Am Soc Nephrol
Title: Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD.
Volume: 28
Issue: 12
Pages: 3490-3503
Publication
First Author: Dworniczak B
Year: 2007
Journal: Nephron Exp Nephrol
Title: Inducible Cre/loxP recombination in the mouse proximal tubule.
Volume: 106
Issue: 1
Pages: e11-20
Publication
First Author: Zhang MZ
Year: 2012
Journal: Diabetes
Title: Intrarenal dopamine inhibits progression of diabetic nephropathy.
Volume: 61
Issue: 10
Pages: 2575-84
Publication
First Author: Yang S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.
Volume: 302
Issue: 6
Pages: F742-9
Publication
First Author: Chen JK
Year: 2015
Journal: J Clin Invest
Title: Phosphatidylinositol 3-kinase signaling determines kidney size.
Volume: 125
Issue: 6
Pages: 2429-44
Publication
First Author: Elias BC
Year: 2014
Journal: J Biol Chem
Title: The integrin β1 subunit regulates paracellular permeability of kidney proximal tubule cells.
Volume: 289
Issue: 12
Pages: 8532-44
Publication
First Author: Han X
Year: 2016
Journal: PLoS One
Title: Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport.
Volume: 11
Issue: 2
Pages: e0147845
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ggt1-cre)M3Egn/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1 Tg(Ggt1-cre)M3Egn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ggt1-cre/ERT2)1Pepe/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Clark PE
Year: 2011
Journal: Am J Pathol
Title: β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.
Volume: 179
Issue: 6
Pages: 3045-55
Publication
First Author: Inoue T
Year: 2010
Journal: J Am Soc Nephrol
Title: Fibroblast expression of an IκB dominant-negative transgene attenuates renal fibrosis.
Volume: 21
Issue: 12
Pages: 2047-52
Publication
First Author: Lovisa S
Year: 2015
Journal: Nat Med
Title: Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.
Volume: 21
Issue: 9
Pages: 998-1009
Publication
First Author: Chen J
Year: 2018
Journal: J Am Soc Nephrol
Title: EGF Receptor-Dependent YAP Activation Is Important for Renal Recovery from AKI.
Volume: 29
Issue: 9
Pages: 2372-2385
Publication
First Author: Qin Y
Year: 2011
Journal: Am J Pathol
Title: Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion.
Volume: 179
Issue: 6
Pages: 2766-78
Publication
First Author: Iwano M
Year: 2002
Journal: J Clin Invest
Title: Evidence that fibroblasts derive from epithelium during tissue fibrosis.
Volume: 110
Issue: 3
Pages: 341-50
Publication
First Author: Kruger C
Year: 2019
Journal: Diabetes
Title: Proximal Tubular Cell-Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis.
Volume: 68
Issue: 4
Pages: 819-831
Publication
First Author: Kim JY
Year: 2020
Journal: Nat Commun
Title: A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury.
Volume: 11
Issue: 1
Pages: 1924
Publication
First Author: Luyten A
Year: 2010
Journal: J Am Soc Nephrol
Title: Aberrant regulation of planar cell polarity in polycystic kidney disease.
Volume: 21
Issue: 9
Pages: 1521-32
Publication
First Author: Hathaway CK
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice.
Volume: 112
Issue: 18
Pages: 5815-20
Publication
First Author: Li A
Year: 2017
Journal: J Cell Mol Med
Title: Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.
Volume: 21
Issue: 8
Pages: 1619-1635
Publication
First Author: LeBleu VS
Year: 2013
Journal: Nat Med
Title: Origin and function of myofibroblasts in kidney fibrosis.
Volume: 19
Issue: 8
Pages: 1047-53
Publication
First Author: Kim I
Year: 2009
Journal: J Am Soc Nephrol
Title: Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin.
Volume: 20
Issue: 12
Pages: 2556-69
Publication
First Author: Starremans PG
Year: 2008
Journal: Kidney Int
Title: A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5' end of Pkd1.
Volume: 73
Issue: 12
Pages: 1394-405
Publication
First Author: Yamada K
Year: 2013
Journal: Exp Anim
Title: Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.
Volume: 62
Issue: 2
Pages: 151-7
Protein
Organism: Mus musculus
Length: 568  
Fragment?: false
Publication
First Author: Heisterkamp N
Year: 2008
Journal: Hum Genet
Title: The human gamma-glutamyltransferase gene family.
Volume: 123
Issue: 4
Pages: 321-32
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Shi ZZ
Year: 1995
Journal: Gene
Title: Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.
Volume: 167
Issue: 1-2
Pages: 233-7
Publication
First Author: Lieberman MW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.
Volume: 93
Issue: 15
Pages: 7923-6
Publication
First Author: Chikhi N
Year: 1999
Journal: Comp Biochem Physiol B Biochem Mol Biol
Title: Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.
Volume: 122
Issue: 4
Pages: 367-80
Publication
First Author: Harding CO
Year: 1997
Journal: J Biol Chem
Title: Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.
Volume: 272
Issue: 19
Pages: 12560-7
Publication
First Author: Levasseur R
Year: 2003
Journal: Endocrinology
Title: Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.
Volume: 144
Issue: 7
Pages: 2761-4
Publication  
First Author: Harris B
Year: 1990
Journal: Mouse Genome
Title: Dwarf grey (dwg).
Volume: 86
Pages: 238
Publication
First Author: Ding D
Year: 2016
Journal: Aging (Albany NY)
Title: N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.
Volume: 8
Issue: 4
Pages: 730-50
Publication
First Author: Will Y
Year: 2000
Journal: Hepatology
Title: gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.
Volume: 32
Issue: 4 Pt 1
Pages: 740-9
Publication
First Author: Chévez-Barrios P
Year: 2000
Journal: Exp Eye Res
Title: Cataract development in gamma-glutamyl transpeptidase-deficient mice.
Volume: 71
Issue: 6
Pages: 575-82
Publication
First Author: Rojas E
Year: 2000
Journal: Mutat Res
Title: Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.
Volume: 447
Issue: 2
Pages: 305-16
Publication
First Author: Kumar TR
Year: 2000
Journal: Endocrinology
Title: Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.
Volume: 141
Issue: 11
Pages: 4270-7
Publication
First Author: Pardo A
Year: 2003
Journal: Am J Respir Crit Care Med
Title: Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.
Volume: 167
Issue: 6
Pages: 925-32
Publication
First Author: Ballatori N
Year: 1998
Journal: Am J Pathol
Title: Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.
Volume: 152
Issue: 4
Pages: 1049-55
Publication
First Author: Lawrence BP
Year: 2000
Journal: Eur J Immunol
Title: Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.
Volume: 30
Issue: 7
Pages: 1902-10
Publication
First Author: Jean JC
Year: 1999
Journal: Mutagenesis
Title: gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.
Volume: 14
Issue: 1
Pages: 31-6
Publication
First Author: Lowry MH
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Lung lining fluid glutathione attenuates IL-13-induced asthma.
Volume: 38
Issue: 5
Pages: 509-16
Publication
First Author: Jean JC
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.
Volume: 283
Issue: 4
Pages: L766-76
Publication
First Author: Klings ES
Year: 2009
Journal: Am J Pathol
Title: Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.
Volume: 175
Issue: 6
Pages: 2309-18
Publication
First Author: West MB
Year: 2010
Journal: J Biol Chem
Title: Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.
Volume: 285
Issue: 38
Pages: 29511-24
Publication
First Author: Will Y
Year: 2002
Journal: Arch Biochem Biophys
Title: In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.
Volume: 397
Issue: 2
Pages: 399-406
Publication
First Author: Curto KA
Year: 1988
Journal: J Histochem Cytochem
Title: Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.
Volume: 36
Issue: 2
Pages: 159-66