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Search results 1 to 100 out of 3713 for Gli2

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Type Details Score
Gene
2736 | GLI2
Type: gene
Organism: human
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Gene
459582 | GLI2
Type: gene
Organism: chimpanzee
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Gene
510255 | GLI2
Type: gene
Organism: cattle
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Gene
100682984 | GLI2
Type: gene
Organism: dog, domestic
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Gene
395956 | GLI2
Type: gene
Organism: chicken
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Gene
705877 | GLI2
Type: gene
Organism: macaque, rhesus
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Gene
100498653 | gli2
Type: gene
Organism: frog, western clawed
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Gene
304729 | Gli2
Type: gene
Organism: rat
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Protein Coding Gene
MGI:95728 | Gli2
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6191647
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191650
Age: embryonic day 18.5
Image: 9A Gli2 WT
Note: Authors report no differences in expression levels between wild-type and null animals.
Specimen Label: 9A Gli2 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6191647
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191650
Age: embryonic day 18.5
Image: 9A Gli2 NULL
Note: Authors report no differences in expression levels between wild-type and null animals.
Specimen Label: 9A Gli2 NULL
Detected: true
Specimen Num: 2
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Publication
9006072 | J:38381
First Author: Mo R
Year: 1997
Journal: Development
Title: Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
Volume: 124
Issue: 1
Pages: 113-23
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Publication
10700170 | J:60757
First Author: Grachtchouk M
Year: 2000
Journal: Nat Genet
Title: Basal cell carcinomas in mice overexpressing Gli2 in skin.
Volume: 24
Issue: 3
Pages: 216-7
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GXD Expression
GXD Expression
 
Probe: MGI:7380633
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380679
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D Gli2 WT (upper)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7380633
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380679
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D Gli2 bromi (upper)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7380633
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380679
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D Gli2 WT (lower)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7380633
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380679
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D Gli2 bromi (lower)
Detected: true
Specimen Num: 4
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Publication
29342244 | J:285602
First Author: Chen JL
Year: 2019
Journal: Cereb Cortex
Title: Gli2 Rescues Delays in Brain Development Induced by Kif3a Dysfunction.
Volume: 29
Issue: 2
Pages: 751-764
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Publication
24463817 | J:258486
First Author: Santos N
Year: 2014
Journal: J Cell Sci
Title: A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity.
Volume: 127
Issue: Pt 7
Pages: 1500-10
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Publication
29205155 | J:255012
   
First Author: Shi Y
Year: 2017
Journal: Elife
Title: Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice.
Volume: 6
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Publication
11783999 | J:72024
First Author: Lewis MT
Year: 2001
Journal: Dev Biol
Title: The Gli2 transcription factor is required for normal mouse mammary gland development.
Volume: 238
Issue: 1
Pages: 133-44
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Publication
26193634 | J:224597
First Author: Kramann R
Year: 2015
Journal: J Clin Invest
Title: Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.
Volume: 125
Issue: 8
Pages: 2935-51
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Publication
18710724 | J:141874
First Author: Cheng W
Year: 2008
Journal: J Urol
Title: Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning.
Volume: 180
Issue: 4
Pages: 1543-50
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Publication
25834022 | J:221426
First Author: Liu J
Year: 2015
Journal: Development
Title: The loss of Hh responsiveness by a non-ciliary Gli2 variant.
Volume: 142
Issue: 9
Pages: 1651-60
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Publication
19056373 | J:145182
First Author: Pan Y
Year: 2009
Journal: Dev Biol
Title: Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development.
Volume: 326
Issue: 1
Pages: 177-89
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Publication
24586787 | J:213826
First Author: Kietzman HW
Year: 2014
Journal: PLoS One
Title: The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.
Volume: 9
Issue: 2
Pages: e89448
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Publication
21559470 | J:172447
First Author: Voronova A
Year: 2011
Journal: PLoS One
Title: Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells.
Volume: 6
Issue: 4
Pages: e19174
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Publication
25695606 | J:279222
 
First Author: Pan YB
Year: 2015
Journal: Cell Death Dis
Title: Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth.
Volume: 6
Pages: e1653
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GXD Expression
GXD Expression
   
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-03-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:1332607
Age: embryonic day 9.5
Note: Gli2 expression is excluded from the anterior floor plate.
Specimen Label: not shown
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1327346
Age: embryonic day 12.5
Image: 12.5 p.c. embryo
Note: Gli2 is expressed in the mesenchyme surrounding the condensing mesenchyme.
Specimen Label: 12.5 p.c. embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1327346
Age: embryonic day 12.5
Image: 12.5 p.c. fore limb
Note: Gli2 is expressed in the mesenchyme surrounding the condensing mesenchyme.
Specimen Label: 12.5 p.c. fore limb
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1327346
Age: embryonic day 12.5
Image: 12.5 p.c. embryo
Note: Gli2 is expressed in the mesenchyme surrounding the condensing mesenchyme.
Specimen Label: 12.5 p.c. embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1327346
Age: embryonic day 11.5
Image: 11.5 p.c. embryo
Note: Gli2 is highly expressed in the developing facial mesenchyme.
Specimen Label: 11.5 p.c. embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1791821
Pattern: Uniform
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 continued to be expressed uniformly around the mandibular incisors.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
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Publication
9027508 | J:38297
First Author: Hughes DC
Year: 1997
Journal: Genomics
Title: Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.
Volume: 39
Issue: 2
Pages: 205-15
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Publication
16316410 | J:103171
First Author: Barnfield PC
Year: 2005
Journal: Differentiation
Title: Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms.
Volume: 73
Issue: 8
Pages: 397-405
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Publication
30554998 | J:272598
First Author: Yin WC
Year: 2019
Journal: Dev Cell
Title: Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Volume: 48
Issue: 2
Pages: 167-183.e5
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Publication
27585885 | J:309495
First Author: Heyne GW
Year: 2016
Journal: Dis Model Mech
Title: Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model.
Volume: 9
Issue: 11
Pages: 1307-1315
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Publication
16880529 | J:111401
First Author: Zhao M
Year: 2006
Journal: Mol Cell Biol
Title: The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.
Volume: 26
Issue: 16
Pages: 6197-208
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Publication
27543868 | J:309224
First Author: Sugiyama Y
Year: 2016
Journal: Pol J Pathol
Title: Gli2 protein expression level is a feasible marker of ligand-dependent hedgehog activation in pancreatic neoplasms.
Volume: 67
Issue: 2
Pages: 136-44
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Publication
16611981 | J:108433
First Author: Pan Y
Year: 2006
Journal: Mol Cell Biol
Title: Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
Volume: 26
Issue: 9
Pages: 3365-77
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Publication
23110168 | J:192305
First Author: Saqui-Salces M
Year: 2012
Journal: PLoS One
Title: Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
Volume: 7
Issue: 10
Pages: e48039
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Publication
19647223 | J:151315
First Author: Ho L
Year: 2009
Journal: Cancer Cell
Title: Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.
Volume: 16
Issue: 2
Pages: 126-36
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Publication
9731531 | J:49603
First Author: Motoyama J
Year: 1998
Journal: Nat Genet
Title: Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.
Volume: 20
Issue: 1
Pages: 54-7
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Publication
16396903 | J:104380
First Author: Hu MC
Year: 2006
Journal: Development
Title: GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.
Volume: 133
Issue: 3
Pages: 569-78
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Publication
9655803 | J:49252
First Author: Hardcastle Z
Year: 1998
Journal: Development
Title: The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.
Volume: 125
Issue: 15
Pages: 2803-11
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Publication
12812795 | J:84056
First Author: Motoyama J
Year: 2003
Journal: Dev Biol
Title: Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.
Volume: 259
Issue: 1
Pages: 150-61
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Publication
14602680 | J:87223
First Author: Buttitta L
Year: 2003
Journal: Development
Title: Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.
Volume: 130
Issue: 25
Pages: 6233-43
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Publication
20503377 | J:160585
First Author: Kesper DA
Year: 2010
Journal: Dev Dyn
Title: Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification.
Volume: 239
Issue: 6
Pages: 1818-26
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 2019-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6355445
Age: embryonic day 9.25
Image: S1 E9.25
Note: Compared to an adjacent section, Gli2 expression overlaps with Foxa2 at E9.25.
Specimen Label: S1 E9.25
Detected: true
Specimen Num: 10
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Publication
21337666 | J:169530
First Author: Li J
Year: 2011
Journal: Dev Dyn
Title: Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo.
Volume: 240
Issue: 4
Pages: 766-74
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Publication
15604102 | J:95326
First Author: McDermott A
Year: 2005
Journal: Development
Title: Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation.
Volume: 132
Issue: 2
Pages: 345-57
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Publication
12533516 | J:81295
First Author: Mill P
Year: 2003
Journal: Genes Dev
Title: Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.
Volume: 17
Issue: 2
Pages: 282-94
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Publication
30791390 | J:282458
 
First Author: Wang Y
Year: 2019
Journal: J Dev Biol
Title: Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia.
Volume: 7
Issue: 1
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Publication
12837627 | J:84432
First Author: Qi Y
Year: 2003
Journal: Mol Cell Neurosci
Title: Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord.
Volume: 23
Issue: 3
Pages: 440-50
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Publication
9636069 | J:49164
First Author: Ding Q
Year: 1998
Journal: Development
Title: Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.
Volume: 125
Issue: 14
Pages: 2533-43
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Publication
19574535 | J:171486
First Author: Rutter M
Year: 2010
Journal: Am J Respir Cell Mol Biol
Title: Gli2 influences proliferation in the developing lung through regulation of cyclin expression.
Volume: 42
Issue: 5
Pages: 615-25
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Publication
22841643 | J:188038
First Author: Bowers M
Year: 2012
Journal: Dev Biol
Title: Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3.
Volume: 370
Issue: 1
Pages: 110-24
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Publication
22549777 | J:186503
First Author: Han L
Year: 2012
Journal: J Biol Chem
Title: Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.
Volume: 287
Issue: 24
Pages: 20483-9
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1327346
Age: embryonic day 10.5
Image: 10.5 p.c. embryo
Note: Gli2 is broadly expressed in the undifferentiated mesenchyme. The zone of polarizing activity shows little or no expression.
Specimen Label: 10.5 p.c. embryo
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-03-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:1332607
Age: embryonic day 8.5
Image: 4D
Note: Gli2 expression overlaps with HNF-3b in the posterior floor plate, but is excluded from the anterior floor plate.
Specimen Label: 4D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 1999-03-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:1332607
Age: embryonic day 8.5
Image: 4I
Note: Gli2 expression overlaps with HNF-3b in the posterior floor plate, but is excluded from the anterior floor plate.
Specimen Label: 4I
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 transcripts in the maxillary incisors were observed to be more strongly expressed medial to the tooth germs.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
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Publication
17026983 | J:119875
First Author: Lebel M
Year: 2007
Journal: Dev Biol
Title: Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain.
Volume: 302
Issue: 1
Pages: 345-55
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Publication
21209421 | J:173724
First Author: Barsoum I
Year: 2011
Journal: Biol Reprod
Title: Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
Volume: 84
Issue: 5
Pages: 894-9
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Publication
10725236 | J:60986
First Author: Park HL
Year: 2000
Journal: Development
Title: Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.
Volume: 127
Issue: 8
Pages: 1593-605
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Publication
28280246 | J:242165
 
First Author: Zhao C
Year: 2017
Journal: Science
Title: Stromal Gli2 activity coordinates a niche signaling program for mammary epithelial stem cells.
Volume: 356
Issue: 6335
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Publication
31167144 | J:284605
First Author: Coquenlorge S
Year: 2019
Journal: Cell Rep
Title: GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.
Volume: 27
Issue: 10
Pages: 3006-3018.e4
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GXD Expression
GXD Expression
Probe: MGI:1331152
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1331156
Age: embryonic day 11.5
Image: 5H
Note: Gli2 is repressed in the facial processes, the distal limb across the A-P axis and in the area of the future femur.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1331152
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1611719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1331156
Age: embryonic day 11.5
Image: 5H
Note: Gli2 is repressed in the facial processes, the distal limb across the A-P axis and in the area of the future femur.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1331152
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1331156
Age: embryonic day 11.5
Image: 5H
Note: Gli2 is repressed in the facial processes, the distal limb across the A-P axis and in the area of the future femur.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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Publication
16254602 | J:115756
First Author: Haycraft CJ
Year: 2005
Journal: PLoS Genet
Title: Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Volume: 1
Issue: 4
Pages: e53
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Publication
28673820 | J:248981
First Author: Li J
Year: 2017
Journal: Dev Biol
Title: PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant.
Volume: 429
Issue: 1
Pages: 147-157
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Publication
10806483 | J:113893
First Author: Murone M
Year: 2000
Journal: Nat Cell Biol
Title: Gli regulation by the opposing activities of fused and suppressor of fused.
Volume: 2
Issue: 5
Pages: 310-2
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Publication
15215207 | J:92067
First Author: Lei Q
Year: 2004
Journal: Development
Title: Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord.
Volume: 131
Issue: 15
Pages: 3593-604
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•
•
•
•
Publication
36252002 | J:335097
First Author: Qin T
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation.
Volume: 119
Issue: 43
Pages: e2206571119
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 2019-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6355445
Age: embryonic day 12.5
Image: S1 E12.5
Note: Compared to adjacent sections, the ventral limit of Gli2 expression abuts the dorsal limit of Foxa2 expression at the alar/basal boundary, and there is a gap between Shh and Gli2 expression in the ventral midbrain.
Specimen Label: S1 E12.5
Detected: true
Specimen Num: 12
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1794021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1320894
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1794121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1320903
Age: embryonic day 13.5
Image: 1Q
Note: Gli2 transcripts in the molars and maxillary incisors were now more localized around the tooth germs and were still detected in both the epithelial and mesenchymal components of the developing teeth.
Specimen Label: 1Q
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
20463034 | J:161408
First Author: Wang C
Year: 2010
Journal: Development
Title: Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.
Volume: 137
Issue: 12
Pages: 2001-9
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•
•
•
•
Publication
9655799 | J:49251
First Author: Matise MP
Year: 1998
Journal: Development
Title: Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system.
Volume: 125
Issue: 15
Pages: 2759-70
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•
•
•
•
Publication
25808752 | J:221866
 
First Author: Yoshida M
Year: 2015
Journal: Nat Commun
Title: The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.
Volume: 6
Pages: 6653
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•
•
•
•
Publication
22007132 | J:181006
First Author: Tuson M
Year: 2011
Journal: Development
Title: Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.
Volume: 138
Issue: 22
Pages: 4921-30
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•
•
•
•
Publication
26795056 | J:231473
First Author: Ringuette R
Year: 2016
Journal: Dev Biol
Title: A Notch-Gli2 axis sustains Hedgehog responsiveness of neural progenitors and Müller glia.
Volume: 411
Issue: 1
Pages: 85-100
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•
•
•
•
Publication
18688029 | J:139587
First Author: Gu LH
Year: 2008
Journal: Am J Pathol
Title: Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions.
Volume: 173
Issue: 3
Pages: 752-61
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•
•
•
•
Publication
25644602 | J:218232
First Author: Chong YC
Year: 2015
Journal: Genes Dev
Title: Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
Volume: 29
Issue: 3
Pages: 262-76
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•
•
•
•
Publication
24194188 | J:229069
First Author: Ringuette R
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Combinatorial hedgehog and mitogen signaling promotes the in vitro expansion but not retinal differentiation potential of retinal progenitor cells.
Volume: 55
Issue: 1
Pages: 43-54
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6279845
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380669
Age: embryonic day 10.5
Note: Ventral neural patterning similar in bromi and Gli2 single mutants
Specimen Label: 3B HB9 Gli2
Detected: true
Specimen Num: 9
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•
•
•
•
Publication
33728992 | J:316859
First Author: Yan J
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Gli2-regulated activation of hepatic stellate cells and liver fibrosis by TGF-β signaling.
Volume: 320
Issue: 5
Pages: G720-G728
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•
•
•
•
Publication
30764875 | J:272495
First Author: Wojcinski A
Year: 2019
Journal: Neural Dev
Title: Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors.
Volume: 14
Issue: 1
Pages: 4
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•
•
•
•
Publication
29202464 | J:258389
First Author: Raleigh DR
Year: 2018
Journal: J Clin Invest
Title: Hedgehog signaling drives medulloblastoma growth via CDK6.
Volume: 128
Issue: 1
Pages: 120-124
•
•
•
•
•
Publication
11238441 | J:114033
First Author: Koyabu Y
Year: 2001
Journal: J Biol Chem
Title: Physical and functional interactions between Zic and Gli proteins.
Volume: 276
Issue: 10
Pages: 6889-92
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•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0014510 | -
Type: protein_coding_gene
Organism: Mus caroli
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•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0016393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0016376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0016341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0016336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0016162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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