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Search results 1 to 100 out of 2097 for Gli3

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: GLI3 is a member of the GLI family of transcription factors, which also includes GLI1 and GLI2. They are central effectors of the Hedgehog (Hh) pathway in vertebrates [, ]. GLI1 is an obligatory activator, whereas GLI2 and GLI3 carry activator and repressor functions []. The full-length GLI3 form, after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while its C-terminally truncated form acts as a repressor (GLI3R). GLI3 participates in the patterning and growth of many organs, including the central nervous system (CNS) and limbs [, , , , ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wang B
Year: 2000
Journal: Cell
Title: Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.
Volume: 100
Issue: 4
Pages: 423-34
Publication
First Author: Wang C
Year: 2007
Journal: Dev Biol
Title: The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning.
Volume: 305
Issue: 2
Pages: 460-9
Publication
First Author: Aoto K
Year: 2002
Journal: Dev Biol
Title: Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud.
Volume: 251
Issue: 2
Pages: 320-32
Publication
First Author: Persson M
Year: 2002
Journal: Genes Dev
Title: Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity.
Volume: 16
Issue: 22
Pages: 2865-78
Publication
First Author: Humke EW
Year: 2010
Journal: Genes Dev
Title: The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Volume: 24
Issue: 7
Pages: 670-82
Protein
Organism: Mus musculus
Length: 1583  
Fragment?: false
Protein
Organism: Mus musculus
Length: 596  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1583  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1583  
Fragment?: false
Publication
First Author: Anwar S
Year: 2015
Journal: Dev Growth Differ
Title: Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development.
Volume: 57
Issue: 8
Pages: 570-80
Publication
First Author: Thien H
Year: 1996
Journal: Biochim Biophys Acta
Title: Cloning and sequence analysis of the murine Gli3 cDNA.
Volume: 1307
Issue: 3
Pages: 267-9
Publication
First Author: Thien H
Year: 1999
Journal: Mamm Genome
Title: The mouse mutation Pdn (Polydactyly Nagoya) is caused by the integration of a retrotransposon into the Gli3 gene.
Volume: 10
Issue: 3
Pages: 205-9
Protein
Organism: Mus musculus
Length: 535  
Fragment?: false
Publication  
First Author: Hui CC
Year: 2011
Journal: Annu Rev Cell Dev Biol
Title: Gli proteins in development and disease.
Volume: 27
Pages: 513-37
Publication
First Author: Nguyen V
Year: 2005
Journal: Development
Title: Cooperative requirement of the Gli proteins in neurogenesis.
Volume: 132
Issue: 14
Pages: 3267-79
Publication
First Author: Pohl TM
Year: 1990
Journal: Development
Title: Evidence for allelism of the recessive insertional mutation add and the dominant mouse mutation extra-toes (Xt).
Volume: 110
Issue: 4
Pages: 1153-7
Publication
First Author: Renault MA
Year: 2009
Journal: Circ Res
Title: The Hedgehog transcription factor Gli3 modulates angiogenesis.
Volume: 105
Issue: 8
Pages: 818-26
Publication
First Author: Büscher D
Year: 1998
Journal: Mamm Genome
Title: The XtJ allele generates a Gli3 fusion transcript.
Volume: 9
Issue: 8
Pages: 676-8
Publication
First Author: Genestine M
Year: 2007
Journal: Genesis
Title: High-resolution mapping of the Gli3 deletion in the mouse extra-toesH mutant.
Volume: 45
Issue: 3
Pages: 107-12
Publication  
First Author: Schimmang T
Year: 1993
Journal: Prog Clin Biol Res
Title: Gli3 expression is affected in the morphogenetic mouse mutants add and Xt.
Volume: 383A
Pages: 153-61
Publication
First Author: Hager-Theodorides AL
Year: 2005
Journal: Blood
Title: The transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.
Volume: 106
Issue: 4
Pages: 1296-304
Publication
First Author: Zaki PA
Year: 2005
Journal: Eur J Neurosci
Title: Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro.
Volume: 22
Issue: 6
Pages: 1547-51
Publication
First Author: Schimmang T
Year: 1992
Journal: Development
Title: Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt).
Volume: 116
Issue: 3
Pages: 799-804
Publication  
First Author: Martin B
Year: 2007
Journal: ScientificWorldJournal
Title: Involvement of the Gli3 (extra-toes) gene region in body weight in mice.
Volume: 7
Pages: 83-6
Publication
First Author: Ulloa F
Year: 2007
Journal: Curr Biol
Title: Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling.
Volume: 17
Issue: 6
Pages: 545-50
Publication
First Author: Maynard TM
Year: 2002
Journal: Mamm Genome
Title: High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion.
Volume: 13
Issue: 1
Pages: 58-61
Publication
First Author: Kang S
Year: 1997
Journal: Nat Genet
Title: GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome.
Volume: 15
Issue: 3
Pages: 266-8
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 2
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 3
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 4
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 2
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 3
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 4
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: There is moderate, scattered staining in the ventricular zone of the dorsal thalamus and prethalamus.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: There is moderate staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is moderate staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 2
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 3
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Num: 4
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450864
Age: embryonic day 11.5
Image: Gli3 - E11.5
Note: There is very strong staining in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Num: 2
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Num: 3
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones.
Specimen Num: 4
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450864
Age: embryonic day 11.5
Image: Gli3 - E11.5
Note: Staining is strong in the VZ of premam zone & TT, moderate in dorsal thalamus & prethalamus, weak & scattered in dorsal & ventral POAs & PVH nucleus & either absent or ubiquitous in AVH, anterior & posterior IDs, VMH & ARH nuclei & mam & supramam zones.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: There is moderate, scattered staining in the VZ of the dorsal and ventral POAs and the PVH nucleus and weak staining in the AVH. Staining is either absent or ubiquitous in the VZ of the anterior and posterior IDs and the VMH and ARH nuclei.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: There is weak staining in the ventricular zone of the dorsal POA. Staining is either absent or ubiquitous in the ventricular zone of the ventral POA, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is moderate staining in the VZ of the ARH nucleus and weak staining in the dorsal and ventral POAs, the PVH nucleus and the AVH. Staining is either absent or ubiquitous in the VZ of the DAH, the SCH, DMH and VMH nuclei and the PH.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450864
Age: embryonic day 11.5
Image: Gli3 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Num: 1
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: There is strong staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: There is very strong staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is very strong staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: There is strong staining in the ventricular zone of the premam zone. Staining is either absent or ubiquitous in the ventricular zone of the mam and supramam zones and the TT.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: There is strong staining in the ventricular zone of the premam zone. Staining is either absent or ubiquitous in the ventricular zone of the mam and supramam zones and the TT.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is very strong staining in the ventricular zone of the premam zone. Staining is either absent or ubiquitous in the ventricular zone of the mam and supramam zones.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is very strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450864
Age: embryonic day 11.5
Image: Gli3 - E11.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Num: 1
GXD Expression  
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450864
Age: embryonic day 12.5
Image: Gli3 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Num: 2
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450864
Age: embryonic day 14.5
Image: Gli3 - E14.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442661
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450864
Age: embryonic day 16.5
Image: Gli3 - E16.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Detected: true
Specimen Num: 4
Publication
First Author: Vortkamp A
Year: 1992
Journal: Mamm Genome
Title: Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt).
Volume: 3
Issue: 8
Pages: 461-3
Publication
First Author: Vortkamp A
Year: 1991
Journal: Nature
Title: GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families.
Volume: 352
Issue: 6335
Pages: 539-40
GXD Expression
Probe: MGI:1320895
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1320904
Age: embryonic day 11.5
Image: 1F
Note: Expression of Gli3 was widespread.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1320895
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1320904
Age: embryonic day 11.5
Image: 1F
Note: Expression of Gli3 was widespread.
Detected: true
Specimen Num: 1
Publication
First Author: Ohba S
Year: 2008
Journal: Dev Cell
Title: Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.
Volume: 14
Issue: 5
Pages: 689-99
Publication
First Author: Hager-Theodorides AL
Year: 2009
Journal: J Immunol
Title: The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms.
Volume: 183
Issue: 5
Pages: 3023-32
Publication
First Author: Ruppert JM
Year: 1990
Journal: Mol Cell Biol
Title: GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity.
Volume: 10
Issue: 10
Pages: 5408-15
Publication
First Author: Panman L
Year: 2005
Journal: Int J Dev Biol
Title: Genetic interaction of Gli3 and Alx4 during limb development.
Volume: 49
Issue: 4
Pages: 443-8
Publication  
First Author: Hyun J
Year: 2016
Journal: Nat Commun
Title: MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.
Volume: 7
Pages: 10993
Publication
First Author: Ueta E
Year: 2002
Journal: Congenit Anom (Kyoto)
Title: Integration of a transposon into the Gli3 gene in the Pdn mouse.
Volume: 42
Issue: 4
Pages: 318-22
Publication
First Author: Ueta E
Year: 2004
Journal: Congenit Anom (Kyoto)
Title: Sonic hedgehog expression in Gli3 depressed mouse embryo, Pdn/Pdn.
Volume: 44
Issue: 1
Pages: 27-32
Publication  
First Author: Abbasi AA
Year: 2010
Journal: BMC Dev Biol
Title: Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development.
Volume: 10
Pages: 44
Publication  
First Author: Yamada Y
Year: 2020
Journal: Neuroscience
Title: Gli3 is a Key Factor in the Schwann Cells from Both Intact and Injured Peripheral Nerves.
Volume: 432
Pages: 229-239
Publication  
First Author: Solanki A
Year: 2018
Journal: Development
Title: Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.
Volume: 145
Issue: 3
Publication
First Author: Hui CC
Year: 1993
Journal: Nat Genet
Title: A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.
Volume: 3
Issue: 3
Pages: 241-6
Publication  
First Author: Veistinen L
Year: 2012
Journal: Front Physiol
Title: Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture.
Volume: 3
Pages: 121
Publication
First Author: Renault MA
Year: 2013
Journal: Circ Res
Title: Gli3 regulation of myogenesis is necessary for ischemia-induced angiogenesis.
Volume: 113
Issue: 10
Pages: 1148-58
Publication
First Author: Balmer CW
Year: 2004
Journal: J Comp Neurol
Title: Loss of Gli3 and Shh function disrupts olfactory axon trajectories.
Volume: 472
Issue: 3
Pages: 292-307
Publication
First Author: Kim JH
Year: 2005
Journal: Dev Dyn
Title: Gli3 null mice display glandular overgrowth of the developing stomach.
Volume: 234
Issue: 4
Pages: 984-91
Publication
First Author: Quinn ME
Year: 2012
Journal: Hum Mol Genet
Title: Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.
Volume: 21
Issue: 8
Pages: 1888-96
Publication
First Author: Rachel RA
Year: 2002
Journal: Genesis
Title: A new allele of Gli3 and a new mutation, circletail (Crc), resulting from a single transgenic experiment.
Volume: 33
Issue: 2
Pages: 55-61
Publication
First Author: Büscher D
Year: 1997
Journal: Mech Dev
Title: Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.
Volume: 62
Issue: 2
Pages: 175-82
Publication
First Author: Motoyama J
Year: 1998
Journal: Nat Genet
Title: Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.
Volume: 20
Issue: 1
Pages: 54-7
Publication
First Author: Wuelling M
Year: 2020
Journal: Dev Biol
Title: Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy.
Volume: 457
Issue: 1
Pages: 104-118
Publication  
First Author: Deimling SJ
Year: 2018
Journal: Mech Dev
Title: Genetic interaction between Gli3 and Ezh2 during limb pattern formation.
Volume: 151
Pages: 30-36
Publication
First Author: Wiegering A
Year: 2019
Journal: Dev Biol
Title: GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis.
Volume: 450
Issue: 2
Pages: 141-154
Publication
First Author: Buttitta L
Year: 2003
Journal: Development
Title: Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.
Volume: 130
Issue: 25
Pages: 6233-43
Publication
First Author: Hardcastle Z
Year: 1998
Journal: Development
Title: The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.
Volume: 125
Issue: 15
Pages: 2803-11
Publication
First Author: Tan M
Year: 2006
Journal: Brain Res
Title: Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants.
Volume: 1067
Issue: 1
Pages: 158-63
Publication  
First Author: Naruse I
Year: 2001
Journal: Congenit Anom (Kyoto)
Title: Phenotypic differences in the brains and limbs of mutant mice caused by differences of Gli3 gene expression levels
Volume: 41
Pages: 89-94
GXD Expression
Probe: MGI:12281
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1327347
Age: embryonic day 12.5
Image: 12.5 p.c. embryo
Note: Gli3 is expressed at a higher level in the autopods.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:12281
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1745920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1327347
Age: embryonic day 12.5
Image: 12.5 p.c. embryo
Note: Gli3 is expressed at a higher level in the autopods.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:12281
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1327347
Age: embryonic day 12.5
Image: 12.5 p.c. fore limb
Note: Gli3 is expressed at higher levels in the autopods.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:12281
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1327347
Age: embryonic day 12.5
Image: 12.5 p.c. fore limb
Note: Gli3 is expressed in the mesenchyme surrounding the condensing mesenchyme.
Detected: true
Specimen Num: 2