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Search results 1 to 100 out of 107 for Glp2r

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0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Glucagon-like peptide 2 (GLP2) acts through G protein-coupled receptor GLP2R and plays a physiological role in the control of food intake and glucose homeostasis. It promotes intestinal epithelial homeostasis and function, enhances intestinal nutrient absorption and blood flow and assists gut immune defense []. GLP2R is not only expressed in nutrient-sensing endocrine cells (such as enteroendocrine cells and pancreatic alpha-cells), but also in neurons [, , ]. GLP2R in hypothalamic POMC neurons is required for promoting hepatic insulin sensitivity and glycemic control. Through GLP2R-p85alpha interaction, GLP2 activates PI3K-Akt-FoxO1 signaling in POMC neurons [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Shi X
Year: 2013
Journal: Cell Metab
Title: Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons.
Volume: 18
Issue: 1
Pages: 86-98
Publication  
First Author: Fuchs S
Year: 2020
Journal: JCI Insight
Title: Loss of Glp2r signaling activates hepatic stellate cells and exacerbates diet-induced steatohepatitis in mice.
Volume: 5
Issue: 8
Publication
First Author: Lee SJ
Year: 2012
Journal: Endocrinology
Title: Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis.
Volume: 153
Issue: 3
Pages: 1141-51
Publication
First Author: Guan X
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis.
Volume: 307
Issue: 6
Pages: R585-96
Publication
First Author: Guan X
Year: 2006
Journal: Gastroenterology
Title: GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.
Volume: 130
Issue: 1
Pages: 150-64
Publication
First Author: Yusta B
Year: 2000
Journal: Gastroenterology
Title: Enteroendocrine localization of GLP-2 receptor expression in humans and rodents.
Volume: 119
Issue: 3
Pages: 744-55
Publication
First Author: Wang Y
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: GLP-2 potentiates L-type Ca2+ channel activity associated with stimulated glucose uptake in hippocampal neurons.
Volume: 298
Issue: 2
Pages: E156-66
Protein
Organism: Mus musculus/domesticus
Length: 48  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
Publication
First Author: Yusta B
Year: 2019
Journal: Endocrinology
Title: Localization of Glucagon-Like Peptide-2 Receptor Expression in the Mouse.
Volume: 160
Issue: 8
Pages: 1950-1963
Publication
First Author: Taher J
Year: 2018
Journal: Endocrinology
Title: GLP-2 Dysregulates Hepatic Lipoprotein Metabolism, Inducing Fatty Liver and VLDL Overproduction in Male Hamsters and Mice.
Volume: 159
Issue: 9
Pages: 3340-3350
Publication
First Author: Koehler JA
Year: 2008
Journal: Cancer Res
Title: Glucagon-like peptide-2 does not modify the growth or survival of murine or human intestinal tumor cells.
Volume: 68
Issue: 19
Pages: 7897-904
Publication
First Author: Guan X
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility.
Volume: 303
Issue: 7
Pages: E853-64
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hunt JE
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2-dependent pathway in mice.
Volume: 318
Issue: 5
Pages: G980-G987
Publication
First Author: Shin ED
Year: 2005
Journal: Gastroenterology
Title: Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice.
Volume: 128
Issue: 5
Pages: 1340-53
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_13
Specimen Label: euxassay_003193_13
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_14
Specimen Label: euxassay_003193_14
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_15
Specimen Label: euxassay_003193_15
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_16
Specimen Label: euxassay_003193_16
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_17
Specimen Label: euxassay_003193_17
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_18
Specimen Label: euxassay_003193_18
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_13
Specimen Label: euxassay_003193_13
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_14
Specimen Label: euxassay_003193_14
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_15
Specimen Label: euxassay_003193_15
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_16
Specimen Label: euxassay_003193_16
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_17
Specimen Label: euxassay_003193_17
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1671523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_18
Specimen Label: euxassay_003193_18
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1789623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_15
Specimen Label: euxassay_003193_15
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_09
Specimen Label: euxassay_003193_09
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_10
Specimen Label: euxassay_003193_10
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_11
Specimen Label: euxassay_003193_11
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_12
Specimen Label: euxassay_003193_12
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_13
Specimen Label: euxassay_003193_13
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_14
Specimen Label: euxassay_003193_14
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_15
Specimen Label: euxassay_003193_15
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_16
Specimen Label: euxassay_003193_16
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_17
Specimen Label: euxassay_003193_17
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_18
Specimen Label: euxassay_003193_18
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_19
Specimen Label: euxassay_003193_19
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_20
Specimen Label: euxassay_003193_20
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_21
Specimen Label: euxassay_003193_21
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1823960
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825078
Age: embryonic day 14.5
Image: euxassay_003193_22
Specimen Label: euxassay_003193_22
Detected: true
Specimen Num: 14
Publication
First Author: Lovshin J
Year: 2001
Journal: J Biol Chem
Title: Glucagon-like peptide (GLP)-2 action in the murine central nervous system is enhanced by elimination of GLP-1 receptor signaling.
Volume: 276
Issue: 24
Pages: 21489-99
Publication
First Author: Shi X
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon-like peptide-2-stimulated protein synthesis through the PI 3-kinase-dependent Akt-mTOR signaling pathway.
Volume: 300
Issue: 3
Pages: E554-63
Publication
First Author: El-Jamal N
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration.
Volume: 307
Issue: 3
Pages: G274-85
Publication
First Author: Bahrami J
Year: 2010
Journal: Gastroenterology
Title: Glucagon-like peptide-2 receptor modulates islet adaptation to metabolic stress in the ob/ob mouse.
Volume: 139
Issue: 3
Pages: 857-68
Publication
First Author: Dubé PE
Year: 2006
Journal: Gastroenterology
Title: The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice.
Volume: 131
Issue: 2
Pages: 589-605
Publication
First Author: Wismann P
Year: 2017
Journal: Mol Metab
Title: The endogenous preproglucagon system is not essential for gut growth homeostasis in mice.
Volume: 6
Issue: 7
Pages: 681-692
Publication
First Author: Yusta B
Year: 2012
Journal: Endocrinology
Title: Intestinotrophic glucagon-like peptide-2 (GLP-2) activates intestinal gene expression and growth factor-dependent pathways independent of the vasoactive intestinal peptide gene in mice.
Volume: 153
Issue: 6
Pages: 2623-32
Publication
First Author: Koehler JA
Year: 2015
Journal: Cell Metab
Title: GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7.
Volume: 21
Issue: 3
Pages: 379-91
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations