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Search results 1 to 100 out of 394 for Gnaq

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Li Z
Year: 2019
Journal: Nat Commun
Title: Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma.
Volume: 10
Issue: 1
Pages: 4209
Publication
First Author: Huang JL
Year: 2015
Journal: Cancer Res
Title: Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.
Volume: 75
Issue: 16
Pages: 3384-97
Publication
First Author: Wang N
Year: 2019
Journal: J Immunol
Title: GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner.
Volume: 203
Issue: 5
Pages: 1288-1297
Publication
First Author: Tepe NM
Year: 1999
Journal: FEBS Lett
Title: Transgenic replacement of type V adenylyl cyclase identifies a critical mechanism of beta-adrenergic receptor dysfunction in the G alpha q overexpressing mouse.
Volume: 458
Issue: 2
Pages: 236-40
Publication
First Author: Lancel S
Year: 2010
Journal: Circ Res
Title: Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice.
Volume: 107
Issue: 2
Pages: 228-32
Publication
First Author: Minamino T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.
Volume: 99
Issue: 6
Pages: 3866-71
Publication
First Author: Fan G
Year: 2005
Journal: J Biol Chem
Title: A transgenic mouse model of heart failure using inducible Galpha q.
Volume: 280
Issue: 48
Pages: 40337-46
Publication
First Author: D'Angelo DD
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Transgenic Galphaq overexpression induces cardiac contractile failure in mice.
Volume: 94
Issue: 15
Pages: 8121-6
Publication
First Author: Westenbrink BD
Year: 2015
Journal: Circ Res
Title: Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation.
Volume: 116
Issue: 5
Pages: e28-39
Publication
First Author: Van Raamsdonk CD
Year: 2004
Journal: Nat Genet
Title: Effects of G-protein mutations on skin color.
Volume: 36
Issue: 9
Pages: 961-8
Publication
First Author: Dong Q
Year: 1995
Journal: Genomics
Title: Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene.
Volume: 30
Issue: 3
Pages: 470-75
Publication  
First Author: Frederick AL
Year: 2012
Journal: Front Behav Neurosci
Title: Neurobehavioral phenotyping of G(αq) knockout mice reveals impairments in motor functions and spatial working memory without changes in anxiety or behavioral despair.
Volume: 6
Pages: 29
Publication
First Author: Wettschureck N
Year: 2005
Journal: Mol Cell Biol
Title: Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.
Volume: 25
Issue: 5
Pages: 1942-8
Publication
First Author: Song Q
Year: 2003
Journal: J Clin Invest
Title: Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
Volume: 111
Issue: 6
Pages: 859-67
Publication    
First Author: Urtatiz O
Year: 2021
Journal: Elife
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
Volume: 10
Publication      
First Author: Urtatiz1 O
Year: 2021
Journal: bioRxiv
Title: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma.
Publication
First Author: Lee MJ
Year: 2012
Journal: J Biol Chem
Title: Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
Volume: 287
Issue: 28
Pages: 24043-52
Publication
First Author: Chew KS
Year: 2014
Journal: PLoS One
Title: Loss of gq/11 genes does not abolish melanopsin phototransduction.
Volume: 9
Issue: 5
Pages: e98356
Publication
First Author: Hughes S
Year: 2015
Journal: Cell Mol Life Sci
Title: Using siRNA to define functional interactions between melanopsin and multiple G Protein partners.
Volume: 72
Issue: 1
Pages: 165-79
Publication
First Author: Patel BR
Year: 2016
Journal: Oncogenesis
Title: Ric-8A gene deletion or phorbol ester suppresses tumorigenesis in a mouse model of GNAQ(Q209L)-driven melanoma.
Volume: 5
Issue: 6
Pages: e236
Publication
First Author: van den Bos E
Year: 2020
Journal: J Biol Chem
Title: Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.
Volume: 295
Issue: 22
Pages: 7726-7742
Publication  
First Author: Wetzel-Strong SE
Year: 2023
Journal: Genetics
Title: Developmental expression of the Sturge-Weber syndrome-associated genetic mutation in Gnaq: a formal test of Happle's paradominant inheritance hypothesis.
Volume: 224
Issue: 4
Publication
First Author: Babwah AV
Year: 2015
Journal: J Neurosci
Title: GnRH Neuron-Specific Ablation of Gαq/11 Results in Only Partial Inactivation of the Neuroendocrine-Reproductive Axis in Both Male and Female Mice: In Vivo Evidence for Kiss1r-Coupled Gαq/11-Independent GnRH Secretion.
Volume: 35
Issue: 37
Pages: 12903-16
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Misra RS
Year: 2010
Journal: J Exp Med
Title: G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity.
Volume: 207
Issue: 8
Pages: 1775-89
Publication
First Author: Kimple AJ
Year: 2009
Journal: J Biol Chem
Title: Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2).
Volume: 284
Issue: 29
Pages: 19402-11
Publication
First Author: Lyon AM
Year: 2013
Journal: Nat Struct Mol Biol
Title: Full-length Gα(q)-phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain.
Volume: 20
Issue: 3
Pages: 355-62
Publication
First Author: Edes IF
Year: 2008
Journal: J Mol Cell Cardiol
Title: Late-stage alterations in myofibrillar contractile function in a transgenic mouse model of dilated cardiomyopathy (Tgalphaq*44).
Volume: 45
Issue: 3
Pages: 363-72
Publication
First Author: Offermanns S
Year: 1997
Journal: Nature
Title: Defective platelet activation in G alpha(q)-deficient mice.
Volume: 389
Issue: 6647
Pages: 183-6
Publication
First Author: Borchers MT
Year: 2002
Journal: J Immunol
Title: Gq signaling is required for allergen-induced pulmonary eosinophilia.
Volume: 168
Issue: 7
Pages: 3543-9
Publication
First Author: Tsubokawa H
Year: 2000
Journal: J Neurosci
Title: Calcium-dependent persistent facilitation of spike backpropagation in the CA1 pyramidal neurons.
Volume: 20
Issue: 13
Pages: 4878-84
Publication
First Author: Offermanns S
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq.
Volume: 94
Issue: 25
Pages: 14089-94
Publication
First Author: Weig HJ
Year: 2008
Journal: J Mol Cell Cardiol
Title: Impaired platelet function reduces myocardial infarct size in Galphaq knock-out mice in vivo.
Volume: 44
Issue: 1
Pages: 143-50
Publication
First Author: Borchers MT
Year: 2003
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Methacholine-induced airway hyperresponsiveness is dependent on Galphaq signaling.
Volume: 285
Issue: 1
Pages: L114-20
Publication
First Author: Garcia EE
Year: 2007
Journal: Neuropharmacology
Title: Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane.
Volume: 52
Issue: 8
Pages: 1671-7
Publication
First Author: Lyon AM
Year: 2011
Journal: Nat Struct Mol Biol
Title: An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation.
Volume: 18
Issue: 9
Pages: 999-1005
Publication
First Author: Nance MR
Year: 2013
Journal: Structure
Title: Structural and functional analysis of the regulator of G protein signaling 2-gαq complex.
Volume: 21
Issue: 3
Pages: 438-48
Publication
First Author: Galvin-Parton PA
Year: 1997
Journal: J Biol Chem
Title: Induction of Galphaq-specific antisense RNA in vivo causes increased body mass and hyperadiposity.
Volume: 272
Issue: 7
Pages: 4335-41
Publication
First Author: Akhter SA
Year: 1998
Journal: Science
Title: Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy.
Volume: 280
Issue: 5363
Pages: 574-7
Publication
First Author: Williams CJ
Year: 1998
Journal: Dev Biol
Title: Evidence that Gq family G proteins do not function in mouse egg activation at fertilization.
Volume: 198
Issue: 1
Pages: 116-27
Publication
First Author: Jacquin-Joly E
Year: 2002
Journal: Eur J Biochem
Title: Expression pattern in the antennae of a newly isolated lepidopteran Gq protein alpha subunit cDNA.
Volume: 269
Issue: 8
Pages: 2133-42
Publication
First Author: Ogata N
Year: 2007
Journal: J Biol Chem
Title: Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation.
Volume: 282
Issue: 49
Pages: 35757-64
Publication
First Author: Keys JR
Year: 2002
Journal: Hypertension
Title: Gq-coupled receptor agonists mediate cardiac hypertrophy via the vasculature.
Volume: 40
Issue: 5
Pages: 660-6
Publication
First Author: Niizeki T
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha(q) signaling cascade.
Volume: 295
Issue: 1
Pages: H245-55
Publication
First Author: Shankaranarayanan A
Year: 2008
Journal: J Biol Chem
Title: Assembly of high order G alpha q-effector complexes with RGS proteins.
Volume: 283
Issue: 50
Pages: 34923-34
Publication
First Author: Li X
Year: 2011
Journal: Circulation
Title: Controlled and cardiac-restricted overexpression of the arginine vasopressin V1A receptor causes reversible left ventricular dysfunction through Gαq-mediated cell signaling.
Volume: 124
Issue: 5
Pages: 572-81
Publication  
First Author: Dahl EF
Year: 2019
Journal: J Mol Cell Cardiol
Title: ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes.
Volume: 127
Pages: 67-73
Publication  
First Author: Wang D
Year: 2017
Journal: Mediators Inflamm
Title: Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation.
Volume: 2017
Pages: 4639081
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: brain +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: brain -/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: spleen +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: spleen -/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: testis +/+
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2661784
Assay Type: Western blot
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661828
Age: postnatal adult
Specimen Label: testis -/-
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2661790
Assay Type: RT-PCR
Annotation Date: 2003-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:2661835
Age: embryonic day 9.5
Specimen Label: G[alpha]q(+/+) G[alpha]11(+/+) G[alpha]q
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2661790
Assay Type: RT-PCR
Annotation Date: 2003-06-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:2661835
Age: embryonic day 9.5
Specimen Label: G[alpha]q(-/-) G[alpha]11(-/-) G[alpha]q
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3654054
Age: embryonic day 0.5
Image: 1
Specimen Label: 1C
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3654054
Age: embryonic day 1.0
Image: 1
Specimen Label: 2C
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3654054
Age: embryonic day 2.0
Image: 1
Specimen Label: 8C
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3654054
Age: embryonic day 3.5
Image: 1
Specimen Label: BL
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3800962
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5 +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3800962
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5 -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3800962
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5 +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3800962
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5 +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3800962
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5 -/-
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3800962
Age: embryonic day 13.5
Image: 4
Specimen Label: 13.5 +/+
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3800915
Assay Type: Western blot
Annotation Date: 2008-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3800962
Age: embryonic day 13.5
Image: 4
Specimen Label: 13.5 -/-
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:3654054
Age: postnatal day 13
Image: 1
Specimen Label: IO
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:3654054
Age: postnatal week 6-8
Image: 1
Specimen Label: CO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3653881
Assay Type: RT-PCR
Annotation Date: 2006-09-09
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3654054
Age: postnatal week 6-8
Image: 1
Specimen Label: E
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7314803
Assay Type: RT-PCR
Annotation Date: 2022-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778722
Stage: TS22
Assay Id: MGI:7314900
Age: embryonic day 14.5
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7314803
Assay Type: RT-PCR
Annotation Date: 2022-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778725
Stage: TS25
Assay Id: MGI:7314900
Age: embryonic day 17.5
Specimen Label: E17
Detected: true
Specimen Num: 2