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Search results 1 to 100 out of 617 for Gnas

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Mehta S
Year: 2015
Journal: PLoS One
Title: Transcription driven somatic DNA methylation within the imprinted Gnas cluster.
Volume: 10
Issue: 2
Pages: e0117378
Publication
First Author: Williamson CM
Year: 2006
Journal: Nat Genet
Title: Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster.
Volume: 38
Issue: 3
Pages: 350-5
Publication
First Author: Williamson CM
Year: 2011
Journal: PLoS Genet
Title: Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.
Volume: 7
Issue: 3
Pages: e1001347
Publication
First Author: Ball ST
Year: 2013
Journal: PLoS One
Title: Gene Dosage Effects at the Imprinted Gnas Cluster.
Volume: 8
Issue: 6
Pages: e65639
Publication
First Author: Holmes R
Year: 2003
Journal: Genome Res
Title: A comprehensive transcript map of the mouse Gnas imprinted complex.
Volume: 13
Issue: 6B
Pages: 1410-5
Publication
First Author: Fröhlich LF
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib.
Volume: 107
Issue: 20
Pages: 9275-80
Publication
First Author: Li T
Year: 2000
Journal: Genomics
Title: Tissue-specific expression of antisense and sense transcripts at the imprinted Gnas locus.
Volume: 69
Issue: 3
Pages: 295-304
Publication
First Author: Williamson CM
Year: 2002
Journal: Mamm Genome
Title: Alternative non-coding splice variants of Nespas, an imprinted gene antisense to Nesp in the Gnas imprinting cluster.
Volume: 13
Issue: 2
Pages: 74-9
Publication
First Author: Wroe SF
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus.
Volume: 97
Issue: 7
Pages: 3342-6
Gene
Type: gene
Organism: human
Publication
First Author: Eaton SA
Year: 2013
Journal: Mamm Genome
Title: Maternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growth.
Volume: 24
Issue: 7-8
Pages: 276-85
Publication
First Author: Schwindinger WF
Year: 1997
Journal: Endocrinology
Title: Targeted disruption of Gnas in embryonic stem cells.
Volume: 138
Issue: 10
Pages: 4058-63
Publication
First Author: Skinner JA
Year: 2002
Journal: Genomics
Title: The imprinted oedematous-small mutation on mouse chromosome 2 identifies new roles for Gnas and Gnasxl in development.
Volume: 80
Issue: 4
Pages: 373-5
Publication
First Author: Lassi G
Year: 2012
Journal: PLoS Genet
Title: Loss of Gnas imprinting differentially affects REM/NREM sleep and cognition in mice.
Volume: 8
Issue: 5
Pages: e1002706
Publication
First Author: Chen M
Year: 2004
Journal: Endocrinology
Title: Increased insulin sensitivity in paternal Gnas knockout mice is associated with increased lipid clearance.
Volume: 145
Issue: 9
Pages: 4094-102
Publication
First Author: Germain-Lee EL
Year: 2005
Journal: Endocrinology
Title: A mouse model of albright hereditary osteodystrophy generated by targeted disruption of exon 1 of the Gnas gene.
Volume: 146
Issue: 11
Pages: 4697-709
Publication
First Author: Fernández-Rebollo E
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.
Volume: 109
Issue: 17
Pages: 6638-43
Publication
First Author: Chen M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.
Volume: 102
Issue: 20
Pages: 7386-91
Publication
First Author: Eaton SA
Year: 2012
Journal: Mol Cell Biol
Title: New mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling.
Volume: 32
Issue: 5
Pages: 1017-29
Publication
First Author: Liu J
Year: 2000
Journal: Mol Cell Biol
Title: Identification of a methylation imprint mark within the mouse Gnas locus.
Volume: 20
Issue: 16
Pages: 5808-17
Publication
First Author: An J
Year: 2019
Journal: J Cell Physiol
Title: GNAS knockdown suppresses osteogenic differentiation of mesenchymal stem cells via activation of Hippo signaling pathway.
Volume: 234
Issue: 12
Pages: 22299-22310
Publication
First Author: Fröhlich LF
Year: 2007
Journal: Endocrinology
Title: Lack of Gnas epigenetic changes and pseudohypoparathyroidism type Ib in mice with targeted disruption of syntaxin-16.
Volume: 148
Issue: 6
Pages: 2925-35
Publication
First Author: Ball ST
Year: 2001
Journal: Mech Dev
Title: The spatial and temporal expression pattern of Nesp and its antisense Nespas, in mid-gestation mouse embryos.
Volume: 100
Issue: 1
Pages: 79-81
Publication
First Author: Peters J
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2.
Volume: 96
Issue: 7
Pages: 3830-5
Publication
First Author: Aydin C
Year: 2009
Journal: Endocrinology
Title: Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha).
Volume: 150
Issue: 8
Pages: 3567-75
Publication
First Author: Cheeseman MT
Year: 2012
Journal: PLoS One
Title: A mouse model for osseous heteroplasia.
Volume: 7
Issue: 12
Pages: e51835
Publication
First Author: Kelly ML
Year: 2009
Journal: Int J Obes (Lond)
Title: A missense mutation in the non-neural G-protein alpha-subunit isoforms modulates susceptibility to obesity.
Volume: 33
Issue: 5
Pages: 507-18
Publication  
First Author: Brewer N
Year: 2021
Journal: Front Genet
Title: Gnas Inactivation Alters Subcutaneous Tissues in Progression to Heterotopic Ossification.
Volume: 12
Pages: 633206
Publication
First Author: Xie T
Year: 2006
Journal: J Biol Chem
Title: The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice.
Volume: 281
Issue: 28
Pages: 18989-99
Publication
First Author: Plagge A
Year: 2004
Journal: Nat Genet
Title: The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding.
Volume: 36
Issue: 8
Pages: 818-26
Publication
First Author: Patra KC
Year: 2018
Journal: Nat Cell Biol
Title: Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
Volume: 20
Issue: 7
Pages: 811-822
Publication
First Author: Regard JB
Year: 2013
Journal: Nat Med
Title: Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.
Volume: 19
Issue: 11
Pages: 1505-12
Publication
First Author: He Q
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo.
Volume: 114
Issue: 45
Pages: E9559-E9568
Publication
First Author: Bastepe M
Year: 2002
Journal: Mol Endocrinol
Title: Receptor-mediated adenylyl cyclase activation through XLalpha(s), the extra-large variant of the stimulatory G protein alpha-subunit.
Volume: 16
Issue: 8
Pages: 1912-9
Publication
First Author: Liu Z
Year: 2011
Journal: Endocrinology
Title: Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo.
Volume: 152
Issue: 4
Pages: 1222-33
Publication
First Author: Liu JJ
Year: 2012
Journal: Stem Cells
Title: Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo.
Volume: 30
Issue: 7
Pages: 1477-85
Publication
First Author: McMullan P
Year: 2022
Journal: JBMR Plus
Title: Parental Origin of Gsα Inactivation Differentially Affects Bone Remodeling in a Mouse Model of Albright Hereditary Osteodystrophy.
Volume: 6
Issue: 1
Pages: e10570
Publication
First Author: Kweon SM
Year: 2017
Journal: Cell Rep
Title: Erasure of Tet-Oxidized 5-Methylcytosine by a SRAP Nuclease.
Volume: 21
Issue: 2
Pages: 482-494
Publication
First Author: Xie T
Year: 2008
Journal: Endocrinology
Title: Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.
Volume: 149
Issue: 5
Pages: 2443-50
Publication
First Author: Liu J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit.
Volume: 102
Issue: 15
Pages: 5513-8
Publication
First Author: Khan SK
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Induced GnasR201H expression from the endogenous Gnas locus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling.
Volume: 115
Issue: 3
Pages: E418-E427
Publication
First Author: Yu S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene.
Volume: 95
Issue: 15
Pages: 8715-20
Publication
First Author: Yu S
Year: 2000
Journal: J Clin Invest
Title: Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism.
Volume: 105
Issue: 5
Pages: 615-23
Publication
First Author: Ecelbarger CA
Year: 1999
Journal: Am J Physiol
Title: Decreased renal Na-K-2Cl cotransporter abundance in mice with heterozygous disruption of the G(s)alpha gene.
Volume: 277
Issue: 2 Pt 2
Pages: F235-44
Publication
First Author: Plagge A
Year: 2005
Journal: Mol Cell Biol
Title: Imprinted Nesp55 influences behavioral reactivity to novel environments.
Volume: 25
Issue: 8
Pages: 3019-26
Publication
First Author: Huso DL
Year: 2011
Journal: PLoS One
Title: Heterotopic ossifications in a mouse model of albright hereditary osteodystrophy.
Volume: 6
Issue: 6
Pages: e21755
Publication
First Author: Xie Y
Year: 2018
Journal: Exp Cell Res
Title: Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice.
Volume: 370
Issue: 2
Pages: 579-590
Publication
First Author: Adams GB
Year: 2009
Journal: Nature
Title: Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Volume: 459
Issue: 7243
Pages: 103-7
Publication
First Author: Dent CL
Year: 2016
Journal: Genes Brain Behav
Title: Impulsive choices in mice lacking imprinted Nesp55.
Volume: 15
Issue: 8
Pages: 693-701
Publication  
First Author: Matthias J
Year: 2020
Journal: Endocrinology
Title: Extra-Large Gα Protein (XLαs) Deficiency Causes Severe Adenine-Induced Renal Injury with Massive FGF23 Elevation.
Volume: 161
Issue: 1
Publication
First Author: Williamson CM
Year: 2004
Journal: Nat Genet
Title: A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas.
Volume: 36
Issue: 8
Pages: 894-9
Publication  
First Author: Ramaswamy G
Year: 2018
Journal: Bone
Title: Ablation of Gsα signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance.
Volume: 109
Pages: 86-90
Publication
First Author: Krechowec SO
Year: 2012
Journal: PLoS One
Title: Postnatal changes in the expression pattern of the imprinted signalling protein XLαs underlie the changing phenotype of deficient mice.
Volume: 7
Issue: 1
Pages: e29753
Publication
First Author: Sakamoto A
Year: 2004
Journal: Hum Mol Genet
Title: Tissue-specific imprinting of the G protein Gsalpha is associated with tissue-specific differences in histone methylation.
Volume: 13
Issue: 8
Pages: 819-28
Publication
First Author: He Q
Year: 2015
Journal: Sci Signal
Title: The G protein α subunit variant XLαs promotes inositol 1,4,5-trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo.
Volume: 8
Issue: 391
Pages: ra84
Publication  
First Author: Ramaswamy G
Year: 2017
Journal: Sci Rep
Title: Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways.
Volume: 7
Pages: 45140
Publication
First Author: Castrop H
Year: 2007
Journal: Cell Tissue Res
Title: Skeletal abnormalities and extra-skeletal ossification in mice with restricted Gsalpha deletion caused by a renin promoter-Cre transgene.
Volume: 330
Issue: 3
Pages: 487-501
Publication
First Author: Qin X
Year: 2017
Journal: Gastroenterology
Title: Heterotrimeric G Stimulatory Protein α Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice.
Volume: 152
Issue: 5
Pages: 1114-1125.e5
Publication
First Author: Sakamoto A
Year: 2005
Journal: J Bone Miner Res
Title: Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.
Volume: 20
Issue: 4
Pages: 663-71
Publication
First Author: Chen M
Year: 2009
Journal: Cell Metab
Title: Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.
Volume: 9
Issue: 6
Pages: 548-55
Publication
First Author: Sinha P
Year: 2016
Journal: J Biol Chem
Title: Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy.
Volume: 291
Issue: 4
Pages: 1631-42
Publication
First Author: Li X
Year: 2012
Journal: J Clin Invest
Title: Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets.
Volume: 122
Issue: 3
Pages: 963-73
Publication  
First Author: Allu PKR
Year: 2021
Journal: J Biol Chem
Title: Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold.
Volume: 296
Pages: 100632
Publication
First Author: Xie T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.
Volume: 104
Issue: 49
Pages: 19601-6
Publication
First Author: Li YQ
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Gsα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight.
Volume: 113
Issue: 2
Pages: 446-51
Publication
First Author: Wu JY
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways.
Volume: 105
Issue: 44
Pages: 16976-81
Publication  
First Author: He L
Year: 2022
Journal: Front Cardiovasc Med
Title: Endothelial G protein stimulatory α-subunit is a critical regulator of post-ischemic angiogenesis.
Volume: 9
Pages: 941946
Publication
First Author: Chen M
Year: 2010
Journal: Cell Metab
Title: G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis.
Volume: 11
Issue: 4
Pages: 320-30
Publication
First Author: Yu S
Year: 2001
Journal: J Biol Chem
Title: Increased insulin sensitivity in Gsalpha knockout mice.
Volume: 276
Issue: 23
Pages: 19994-8
Publication  
First Author: Fulzele K
Year: 2018
Journal: Bone
Title: Loss of Gsα in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity.
Volume: 117
Pages: 138-148
Publication
First Author: Chen M
Year: 2012
Journal: Endocrinology
Title: Gsα deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsα mutations.
Volume: 153
Issue: 9
Pages: 4256-65
Publication
First Author: Berger A
Year: 2016
Journal: Endocrinology
Title: Gsα Deficiency in the Ventromedial Hypothalamus Enhances Leptin Sensitivity and Improves Glucose Homeostasis in Mice on a High-Fat Diet.
Volume: 157
Issue: 2
Pages: 600-10
Publication
First Author: Wu JY
Year: 2011
Journal: J Clin Invest
Title: Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.
Volume: 121
Issue: 9
Pages: 3492-504
Publication
First Author: Guilherme A
Year: 2020
Journal: Cell Rep
Title: Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.
Volume: 31
Issue: 5
Pages: 107598
Publication  
First Author: Chinn AM
Year: 2022
Journal: Front Pharmacol
Title: PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells.
Volume: 13
Pages: 833832
Publication
First Author: Lachmann P
Year: 2017
Journal: J Am Soc Nephrol
Title: Interference with Gsα-Coupled Receptor Signaling in Renin-Producing Cells Leads to Renal Endothelial Damage.
Volume: 28
Issue: 12
Pages: 3479-3489
Publication
First Author: Wand G
Year: 2001
Journal: J Neurosci
Title: The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol.
Volume: 21
Issue: 14
Pages: 5297-303
Publication
First Author: Chen M
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
Volume: 296
Issue: 4
Pages: C930-40
Publication
First Author: Feng HZ
Year: 2008
Journal: J Biol Chem
Title: Removal of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signaling.
Volume: 283
Issue: 48
Pages: 33384-93
Publication
First Author: Sakamoto A
Year: 2005
Journal: J Biol Chem
Title: Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone.
Volume: 280
Issue: 22
Pages: 21369-75
Publication
First Author: Chen M
Year: 2005
Journal: J Clin Invest
Title: Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency.
Volume: 115
Issue: 11
Pages: 3217-27
Publication
First Author: Hayward BE
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Bidirectional imprinting of a single gene: GNAS1 encodes maternally, paternally, and biallelically derived proteins.
Volume: 95
Issue: 26
Pages: 15475-80
Publication
First Author: Fulzele K
Year: 2017
Journal: J Bone Miner Res
Title: Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots.
Volume: 32
Issue: 2
Pages: 373-384
Publication
First Author: Chen L
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells.
Volume: 292
Issue: 1
Pages: F27-37
Publication
First Author: Iglesias-Bartolome R
Year: 2015
Journal: Nat Cell Biol
Title: Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.
Volume: 17
Issue: 6
Pages: 793-803
Publication      
First Author: Wu VH
Year: 2023
Journal: Nat Immunol
Title: The GPCR-Gα(s)-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.
Publication  
First Author: Serra-Navarro B
Year: 2021
Journal: Mol Metab
Title: Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass.
Volume: 53
Pages: 101264
Publication
First Author: Lee J
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cyclic AMP concentrations in dendritic cells induce and regulate Th2 immunity and allergic asthma.
Volume: 112
Issue: 5
Pages: 1529-34
Publication  
First Author: Tafaj O
Year: 2017
Journal: Bone
Title: Mice maintain predominantly maternal Gαs expression throughout life in brown fat tissue (BAT), but not other tissues.
Volume: 103
Pages: 177-187
Publication
First Author: Saggio I
Year: 2014
Journal: J Bone Miner Res
Title: Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history.
Volume: 29
Issue: 11
Pages: 2357-68