|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 160 for Gpbar1

<< First    < Previous  |  Next >    Last >>
0.045s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Vassileva G
Year: 2006
Journal: Biochem J
Title: Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation.
Volume: 398
Issue: 3
Pages: 423-30
Publication
First Author: Vassileva G
Year: 2010
Journal: J Endocrinol
Title: Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice.
Volume: 205
Issue: 3
Pages: 225-32
Publication
First Author: Lund ML
Year: 2020
Journal: Diabetes
Title: L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling.
Volume: 69
Issue: 4
Pages: 614-623
Publication
First Author: Carino A
Year: 2017
Journal: Sci Rep
Title: Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.
Volume: 7
Issue: 1
Pages: 13689
Publication
First Author: Carino A
Year: 2021
Journal: FASEB J
Title: The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
Volume: 35
Issue: 1
Pages: e21271
Publication
First Author: Lavoie B
Year: 2010
Journal: J Physiol
Title: Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.
Volume: 588
Issue: Pt 17
Pages: 3295-305
Publication
First Author: Carino A
Year: 2019
Journal: FASEB J
Title: Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
Volume: 33
Issue: 2
Pages: 2809-2822
Publication
First Author: Biagioli M
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis.
Volume: 8
Issue: 3
Pages: 447-473
Publication
First Author: Biagioli M
Year: 2017
Journal: J Immunol
Title: The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.
Volume: 199
Issue: 2
Pages: 718-733
Publication
First Author: Biagioli M
Year: 2020
Journal: J Immunol
Title: The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
Volume: 204
Issue: 9
Pages: 2535-2551
Publication  
First Author: Li W
Year: 2023
Journal: Phytomedicine
Title: Red ginseng extracts ameliorate high-fat diet-induced obesity and insulin resistance by activating the intestinal TGR5-mediated bile acids signaling pathway.
Volume: 119
Pages: 154982
Publication
First Author: Alemi F
Year: 2013
Journal: J Clin Invest
Title: The TGR5 receptor mediates bile acid-induced itch and analgesia.
Volume: 123
Issue: 4
Pages: 1513-30
Publication
First Author: Thomas C
Year: 2009
Journal: Cell Metab
Title: TGR5-mediated bile acid sensing controls glucose homeostasis.
Volume: 10
Issue: 3
Pages: 167-77
Publication  
First Author: Klindt C
Year: 2019
Journal: Cells
Title: The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver.
Volume: 8
Issue: 11
Publication  
First Author: Biagioli M
Year: 2020
Journal: Biochem Pharmacol
Title: Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1.
Volume: 177
Pages: 113987
Publication
First Author: Maruyama T
Year: 2006
Journal: J Endocrinol
Title: Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
Volume: 191
Issue: 1
Pages: 197-205
Publication
First Author: Wu Q
Year: 2021
Journal: Cell Metab
Title: Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis.
Volume: 33
Issue: 10
Pages: 1988-2003.e7
Publication  
First Author: Castro J
Year: 2019
Journal: JCI Insight
Title: Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity.
Volume: 4
Issue: 20
Publication
First Author: Renga B
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Volume: 309
Issue: 1
Pages: H114-26
Publication
First Author: Ibrahim E
Year: 2018
Journal: Sci Rep
Title: Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5.
Volume: 8
Issue: 1
Pages: 7110
Publication
First Author: Caldwell A
Year: 2022
Journal: Sci Rep
Title: TGR5 agonists induce peripheral and central hypersensitivity to bladder distension.
Volume: 12
Issue: 1
Pages: 9920
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Maruyama T
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Identification of membrane-type receptor for bile acids (M-BAR).
Volume: 298
Issue: 5
Pages: 714-9
Publication
First Author: Kawamata Y
Year: 2003
Journal: J Biol Chem
Title: A G protein-coupled receptor responsive to bile acids.
Volume: 278
Issue: 11
Pages: 9435-40
Publication  
First Author: Holter MM
Year: 2020
Journal: Nutrients
Title: Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice.
Volume: 12
Issue: 7
Publication
First Author: Velazquez-Villegas LA
Year: 2018
Journal: Nat Commun
Title: TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue.
Volume: 9
Issue: 1
Pages: 245
Publication
First Author: Syring KE
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Systemic bile acids induce insulin resistance in a TGR5-independent manner.
Volume: 316
Issue: 5
Pages: E782-E793
Publication  
First Author: Bensalem A
Year: 2020
Journal: J Nutr Biochem
Title: Bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity.
Volume: 76
Pages: 108298
Publication
First Author: Cipriani S
Year: 2011
Journal: PLoS One
Title: The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis.
Volume: 6
Issue: 10
Pages: e25637
Publication
First Author: Péan N
Year: 2013
Journal: Hepatology
Title: The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice.
Volume: 58
Issue: 4
Pages: 1451-60
Publication
First Author: Reddy IA
Year: 2018
Journal: PLoS Biol
Title: Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
Volume: 16
Issue: 7
Pages: e2006682
Publication
First Author: Willis KA
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: TGR5 signaling mitigates parenteral nutrition-associated liver disease.
Volume: 318
Issue: 2
Pages: G322-G335
Publication
First Author: Donepudi AC
Year: 2017
Journal: Hepatology
Title: G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice.
Volume: 65
Issue: 3
Pages: 813-827
Publication  
First Author: Abrigo J
Year: 2020
Journal: Int J Mol Sci
Title: Sarcopenia Induced by Chronic Liver Disease in Mice Requires the Expression of the Bile Acids Membrane Receptor TGR5.
Volume: 21
Issue: 21
Publication
First Author: Baptissart M
Year: 2014
Journal: Hepatology
Title: Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice.
Volume: 60
Issue: 3
Pages: 1054-65
Publication
First Author: Abrigo J
Year: 2021
Journal: J Cell Physiol
Title: Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor.
Volume: 236
Issue: 1
Pages: 260-272
Publication
First Author: Cortés V
Year: 2015
Journal: PLoS One
Title: Metabolic effects of cholecystectomy: gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice.
Volume: 10
Issue: 3
Pages: e0118478
Publication
First Author: Rao J
Year: 2020
Journal: Int Immunol
Title: Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex.
Volume: 32
Issue: 5
Pages: 321-334
Publication
First Author: Lajczak NK
Year: 2017
Journal: FASEB J
Title: Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic epithelial cells.
Volume: 31
Issue: 9
Pages: 3848-3857
Publication
First Author: McMillin M
Year: 2015
Journal: J Neurochem
Title: TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.
Volume: 135
Issue: 3
Pages: 565-76
Publication
First Author: Li ZY
Year: 2019
Journal: Mol Med Rep
Title: Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II‑induced arthritis.
Volume: 20
Issue: 5
Pages: 4540-4550
Publication
First Author: Li S
Year: 2018
Journal: J Am Soc Nephrol
Title: Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis.
Volume: 29
Issue: 11
Pages: 2658-2670
Publication  
First Author: Wang J
Year: 2020
Journal: J Mol Cell Cardiol
Title: DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction.
Volume: 151
Pages: 3-14
Publication
First Author: Han M
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Activation of TGR5 restores AQP2 expression via the HIF pathway in renal ischemia-reperfusion injury.
Volume: 320
Issue: 3
Pages: F308-F321
Publication
First Author: Wang H
Year: 2021
Journal: Biol Psychiatry
Title: Takeda G Protein-Coupled Receptor 5 Modulates Depression-like Behaviors via Hippocampal CA3 Pyramidal Neurons Afferent to Dorsolateral Septum.
Volume: 89
Issue: 11
Pages: 1084-1095
Publication  
First Author: Sasaki T
Year: 2021
Journal: J Biol Chem
Title: Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice.
Volume: 296
Pages: 100131
Publication  
First Author: Xiong Q
Year: 2018
Journal: Front Immunol
Title: Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses.
Volume: 9
Pages: 2289
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870063
Note: vas deferens
Specimen Label: UC Davis_1870063
Detected: true
Specimen Num: 16
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870064
Note: vas deferens
Specimen Label: UC Davis_1870064
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870067
Specimen Label: UC Davis_1870067
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870068
Specimen Label: UC Davis_1870068
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870058
Specimen Label: UC Davis_1870058
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870069
Specimen Label: UC Davis_1870069
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1866628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870056
Specimen Label: UC Davis_1870056
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870061
Specimen Label: UC Davis_1870061
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870062
Specimen Label: UC Davis_1870062
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1885228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870055
Specimen Label: UC Davis_1870055
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870053
Specimen Label: UC Davis_1870053
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870054
Specimen Label: UC Davis_1870054
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870059
Specimen Label: UC Davis_1870059
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870060
Specimen Label: UC Davis_1870060
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870065
Specimen Label: UC Davis_1870065
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870066
Specimen Label: UC Davis_1870066
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692754
Age: postnatal adult
Image: UC Davis_1870057
Specimen Label: UC Davis_1870057
Detected: true
Specimen Num: 10
Publication  
First Author: Islam J
Year: 2022
Journal: Front Immunol
Title: GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 766919
Publication
First Author: Sorrentino G
Year: 2020
Journal: Gastroenterology
Title: Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration.
Volume: 159
Issue: 3
Pages: 956-968.e8
Publication
First Author: Perino A
Year: 2021
Journal: Nat Metab
Title: Central anorexigenic actions of bile acids are mediated by TGR5.
Volume: 3
Issue: 5
Pages: 595-603
Publication  
First Author: Somm E
Year: 2017
Journal: JCI Insight
Title: β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.
Volume: 2
Issue: 8
Publication
First Author: Merlen G
Year: 2020
Journal: Gut
Title: TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.
Volume: 69
Issue: 1
Pages: 146-157
Publication
First Author: Rajagopal S
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway.
Volume: 304
Issue: 5
Pages: G527-35
Publication  
First Author: Harach T
Year: 2012
Journal: Sci Rep
Title: TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.
Volume: 2
Pages: 430
Publication
First Author: Sasaki T
Year: 2018
Journal: J Biol Chem
Title: The exercise-inducible bile acid receptor Tgr5 improves skeletal muscle function in mice.
Volume: 293
Issue: 26
Pages: 10322-10332
Publication    
First Author: Donkers JM
Year: 2019
Journal: JCI Insight
Title: NTCP deficiency in mice protects against obesity and hepatosteatosis.
Volume: 5