| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
G-protein coupled receptor 143 (also known as ocular albinism type 1, OA1) is a receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, it stimulates Ca2+ influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalises beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells []. Ocular albinism type 1 is an X-linked disorder characterisedby severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes. A novel transcript from the OA1 critical region is expressed in high levels in RNA samples from retina and from melanoma and encodes a potential integral membrane protein []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masukawa D |
| Year: |
2023 |
| Journal: |
J Neurochem |
| Title: |
Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum. |
| Volume: |
165 |
| Issue: |
2 |
| Pages: |
177-195 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
405
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
405
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
183
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bassi MT |
| Year: |
1995 |
| Journal: |
Nat Genet |
| Title: |
Cloning of the gene for ocular albinism type 1 from the distal short arm of the X chromosome. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
13-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Poulain P |
| Year: |
1991 |
| Journal: |
J Gynecol Obstet Biol Reprod (Paris) |
| Title: |
[Autoimmune thrombocytopenic purpura and pregnancy: significance of fetal blood punction]. |
| Volume: |
20 |
| Issue: |
3 |
| Pages: |
343-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arai M |
| Year: |
2024 |
| Journal: |
J Neurosci |
| Title: |
Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in Striatal Cholinergic Interneurons. |
| Volume: |
44 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bassi MT |
| Year: |
1996 |
| Journal: |
Genome Res |
| Title: |
Cloning of the murine homolog of the ocular albinism type 1 (OA1) gene: sequence, genomic structure, and expression analysis in pigment cells. |
| Volume: |
6 |
| Issue: |
9 |
| Pages: |
880-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palmisano I |
| Year: |
2008 |
| Journal: |
Hum Mol Genet |
| Title: |
The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells. |
| Volume: |
17 |
| Issue: |
22 |
| Pages: |
3487-501 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Incerti B |
| Year: |
2000 |
| Journal: |
Hum Mol Genet |
| Title: |
Oa1 knock-out: new insights on the pathogenesis of ocular albinism type 1. |
| Volume: |
9 |
| Issue: |
19 |
| Pages: |
2781-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Surace EM |
| Year: |
2005 |
| Journal: |
Mol Ther |
| Title: |
Amelioration of both functional and morphological abnormalities in the retina of a mouse model of ocular albinism following AAV-mediated gene transfer. |
| Volume: |
12 |
| Issue: |
4 |
| Pages: |
652-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fukuda N |
| Year: |
2015 |
| Journal: |
Brain Res |
| Title: |
Expression of ocular albinism 1 (OA1), 3, 4- dihydroxy- L-phenylalanine (DOPA) receptor, in both neuronal and non-neuronal organs. |
| Volume: |
1602 |
|
| Pages: |
62-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Samaraweera P |
| Year: |
2001 |
| Journal: |
Exp Eye Res |
| Title: |
The mouse ocular albinism 1 gene product is an endolysosomal protein. |
| Volume: |
72 |
| Issue: |
3 |
| Pages: |
319-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schnur RE |
| Year: |
1998 |
| Journal: |
Am J Hum Genet |
| Title: |
OA1 mutations and deletions in X-linked ocular albinism. |
| Volume: |
62 |
| Issue: |
4 |
| Pages: |
800-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Staleva L |
| Year: |
2006 |
| Journal: |
Exp Eye Res |
| Title: |
Ocular albinism 1 protein: trafficking and function when expressed in Saccharomyces cerevisiae. |
| Volume: |
82 |
| Issue: |
2 |
| Pages: |
311-8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:3815041 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
E10.5 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:3815041 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815041 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
skin |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815041 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
eye |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815041 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
brain |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815041 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
adrenal |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815041 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
heart |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752527 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 1.5 |
|
|
| Specimen Label: |
P1.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752527 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 3.5 |
|
|
| Specimen Label: |
P3.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 5.5 |
|
|
| Specimen Label: |
P5.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 7.5 |
|
|
| Specimen Label: |
P7.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 5.5 |
|
|
| Specimen Label: |
P5.5 dorsal |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815042 |
| Age: |
postnatal day 5.5 |
|
|
| Specimen Label: |
P5.5 ventral |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:3815044 |
| Age: |
postnatal day 0.5 |
|
|
| Specimen Label: |
P.05 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:3815044 |
| Age: |
postnatal day 1.5 |
|
|
| Specimen Label: |
P1.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:3815044 |
| Age: |
postnatal day 2.5 |
|
|
| Specimen Label: |
P2.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815044 |
| Age: |
postnatal day 5.5 |
|
|
| Specimen Label: |
P5.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815044 |
| Age: |
postnatal day 9.5 |
|
|
| Specimen Label: |
P9.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815045 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2008-11-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3815046 |
| Age: |
postnatal |
|
|
| Specimen Label: |
eye |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2009-05-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3845483 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Not shown |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2009-05-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3845483 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Not shown |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3815038 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2009-05-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3845483 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Not shown |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185815 |
|
| Stage: |
TS15 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
E9.5 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185817 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185820 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
E12.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619822 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
E14.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619824 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
E16.5 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6489589 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
E18.5 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:6489589 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
P0 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6489589 |
| Age: |
postnatal day 6 |
|
|
| Specimen Label: |
P6 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489584 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6489589 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Ad |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619824 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression in neural crest-derived melanocytes of harderian gland. |
| Specimen Label: |
E16.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6489591 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6489591 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
adult not shown |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906526 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Expression extended to ciliary body. |
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3573819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Expression in all cells of extenal layer of optic cup. Expression expanded from dorsal to ventral side. |
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619424 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Beginning at E16.5, expression in neural crest-derived melanocytes of eyelids, hair follicles and inner ear. |
| Specimen Label: |
E16.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1667417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Expression localized in dorsal side of optic cup. Expression appeared symmetric without any bias to nasal or temporal side. |
| Specimen Label: |
2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1667417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Expression restricted to dorsal part of optic cup. Expression only in external layer fated to become retinal pigment epithelium. |
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1782924 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Beginning at E16.5, expression in neural crest-derived melanocytes of eyelids, hair follicles and inner ear. |
| Specimen Label: |
E16.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1877124 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Beginning at E16.5, expression in neural crest-derived melanocytes of eyelids, hair follicles and inner ear. |
| Specimen Label: |
E16.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6489585 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-01-04 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1654015 |
|
| Stage: |
TS15 |
| Assay Id: |
MGI:6489591 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
E9.5 not shown |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giordano F |
| Year: |
2009 |
| Journal: |
Hum Mol Genet |
| Title: |
The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition. |
| Volume: |
18 |
| Issue: |
23 |
| Pages: |
4530-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vetrini F |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis. |
| Volume: |
24 |
| Issue: |
15 |
| Pages: |
6550-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Young A |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
A constitutively active Gαi3 protein corrects the abnormal retinal pigment epithelium phenotype of Oa1-/- mice. |
| Volume: |
8 |
| Issue: |
9 |
| Pages: |
e76240 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cortese K |
| Year: |
2005 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
The ocular albinism type 1 (OA1) gene controls melanosome maturation and size. |
| Volume: |
46 |
| Issue: |
12 |
| Pages: |
4358-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Newton JM |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene. |
| Volume: |
37 |
| Issue: |
2 |
| Pages: |
219-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Young A |
| Year: |
2008 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation. |
| Volume: |
49 |
| Issue: |
7 |
| Pages: |
3245-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Young A |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Specific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium. |
| Volume: |
6 |
| Issue: |
9 |
| Pages: |
e24376 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Surace EM |
| Year: |
2000 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Expression pattern of the ocular albinism type 1 (Oa1) gene in the murine retinal pigment epithelium. |
| Volume: |
41 |
| Issue: |
13 |
| Pages: |
4333-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dinulos MB |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
A new region of conservation is defined between human and mouse X chromosomes. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
244-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blair HJ |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
An integrated genetic and man-mouse comparative map of the DXHXS674-Pdha1 region of the mouse X chromosome. |
| Volume: |
48 |
| Issue: |
1 |
| Pages: |
128-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Montini E |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region. |
| Volume: |
51 |
| Issue: |
3 |
| Pages: |
427-33 |
|
•
•
•
•
•
|