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Search results 1 to 100 out of 100 for Gps2

0.044s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
2874 | GPS2
Type: gene
Organism: human
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Gene
100135707 | gps2
Type: gene
Organism: frog, western clawed
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Gene
121108913 | GPS2
Type: gene
Organism: chicken
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Gene
497941 | Gps2
Type: gene
Organism: rat
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Gene
455229 | GPS2
Type: gene
Organism: chimpanzee
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Gene
518494 | GPS2
Type: gene
Organism: cattle
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Gene
100855803 | GPS2
Type: gene
Organism: dog, domestic
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Gene
393948 | gps2
Type: gene
Organism: zebrafish
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Gene
721816 | GPS2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1891751 | Gps2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR026094 | GPS2
Type: Family
Description: G protein pathway suppressor 2 is involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this protein could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this protein may be signal repression []. This protein is a component of the N-CoR-HDAC3 []and also the SMRT corepressor complexes [].
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Publication
32937117 | J:300599
First Author: Drareni K
Year: 2020
Journal: Cell Rep
Title: Adipocyte Reprogramming by the Transcriptional Coregulator GPS2 Impacts Beta Cell Insulin Secretion.
Volume: 32
Issue: 11
Pages: 108141
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Publication
32384137 | J:301392
First Author: Ma WB
Year: 2020
Journal: Blood
Title: GPS2 promotes erythroid differentiation by control of the stability of EKLF protein.
Volume: 135
Issue: 25
Pages: 2302-2315
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Publication
29499132 | J:259114
First Author: Cardamone MD
Year: 2018
Journal: Mol Cell
Title: Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation.
Volume: 69
Issue: 5
Pages: 757-772.e7
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Publication
30208320 | J:270900
First Author: Drareni K
Year: 2018
Journal: Cell Rep
Title: GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation.
Volume: 24
Issue: 11
Pages: 2957-2971.e6
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Publication
28123943 | J:260026
First Author: Cederquist CT
Year: 2017
Journal: Mol Metab
Title: Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue.
Volume: 6
Issue: 1
Pages: 125-137
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Publication
30975991 | J:275570
First Author: Liang N
Year: 2019
Journal: Nat Commun
Title: Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Volume: 10
Issue: 1
Pages: 1684
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Publication
28039360 | J:240887
First Author: Lentucci C
Year: 2017
Journal: J Biol Chem
Title: Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development.
Volume: 292
Issue: 7
Pages: 2754-2772
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Publication
33503407 | J:305187
First Author: Huang Z
Year: 2021
Journal: Mol Cell
Title: The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.
Volume: 81
Issue: 5
Pages: 953-968.e9
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Publication
27270589 | J:239857
First Author: Fan R
Year: 2016
Journal: Nat Med
Title: Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.
Volume: 22
Issue: 7
Pages: 780-91
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Publication
11931768 | -
First Author: Zhang J
Year: 2002
Journal: Mol Cell
Title: The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.
Volume: 9
Issue: 3
Pages: 611-23
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Protein
Q921N8
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
Q9WV81
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
J3QNR4
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Publication
8943324 | -
First Author: Spain BH
Year: 1996
Journal: Mol Cell Biol
Title: Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.
Volume: 16
Issue: 12
Pages: 6698-706
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Publication
19858209 | -
First Author: Cheng X
Year: 2009
Journal: J Biol Chem
Title: G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.
Volume: 284
Issue: 52
Pages: 36395-404
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Publication
24953653 | J:259113
First Author: Cardamone MD
Year: 2014
Journal: Cell Rep
Title: GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ.
Volume: 8
Issue: 1
Pages: 163-76
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Publication
25519902 | J:219351
First Author: Guo C
Year: 2015
Journal: J Biol Chem
Title: The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor γ requires G protein pathway suppressor 2.
Volume: 290
Issue: 6
Pages: 3666-79
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Publication
22424771 | J:259118
First Author: Cardamone MD
Year: 2012
Journal: Mol Cell
Title: A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.
Volume: 46
Issue: 1
Pages: 91-104
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Publication
36731652 | J:361174
 
First Author: English J
Year: 2023
Journal: Mol Metab
Title: GPS2-mediated regulation of the adipocyte secretome modulates adipose tissue remodeling at the onset of diet-induced obesity.
Volume: 69
Pages: 101682
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Publication
22666460 | J:243390
First Author: Liu XF
Year: 2012
Journal: PLoS One
Title: ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.
Volume: 7
Issue: 5
Pages: e38130
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Publication
30153049 | J:285601
First Author: Huang Z
Year: 2019
Journal: FASEB J
Title: G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.
Volume: 33
Issue: 2
Pages: 1631-1643
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Publication
26070566 | J:224604
First Author: Huang J
Year: 2015
Journal: J Biol Chem
Title: Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.
Volume: 290
Issue: 31
Pages: 19044-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0016604 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018505 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1891751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029386 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018403 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019001 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017930 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017735 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017440 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:65077
   
First Author: Gao Y
Year: 1999
Journal: GenBank Submission
Title: Mus musculus G protein pathway suppressor 2 mRNA, complete cds
Pages: AF153696
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Publication
20159957 | J:156993
First Author: Venteclef N
Year: 2010
Journal: Genes Dev
Title: GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.
Volume: 24
Issue: 4
Pages: 381-95
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Publication
18218630 | J:135288
First Author: Zhang D
Year: 2008
Journal: J Biol Chem
Title: G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.
Volume: 283
Issue: 13
Pages: 8580-90
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Publication
15695367 | J:98538
First Author: Ishizuka T
Year: 2005
Journal: Mol Endocrinol
Title: The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.
Volume: 19
Issue: 6
Pages: 1443-51
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
17895379 | -
First Author: Sanyal S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.
Volume: 104
Issue: 40
Pages: 15665-70
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Allele
Gps2<em1Smoc> | MGI:7290627
Name: G protein pathway suppressor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein
Q8BK32
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
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Protein Domain
IPR031557 | N-CoR_GPS2_interact
Type: Domain
Description: The G-protein pathway suppressor 2 (GPS2)-interacting domain is found in NCoR (nuclear receptor corepressor) proteins. NCoR1 and NCoR2 (also known as SMRT) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways [].
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Publication
27052179 | J:235080
First Author: Thiagarajan D
Year: 2016
Journal: Cell Rep
Title: Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.
Volume: 15
Issue: 1
Pages: 181-96
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Protein
Q60974
Organism: Mus musculus/domesticus
Length: 2453  
Fragment?: false
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Protein
Q9WU42
Organism: Mus musculus/domesticus
Length: 2472  
Fragment?: false
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Protein
E9Q701
Organism: Mus musculus/domesticus
Length: 2473  
Fragment?: false
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Protein
E9Q2B2
Organism: Mus musculus/domesticus
Length: 2386  
Fragment?: false
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Protein
Q05C35
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: true
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Protein
E9Q8K6
Organism: Mus musculus/domesticus
Length: 791  
Fragment?: true
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Protein
Q5RIN0
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: true
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Protein
E9Q9V3
Organism: Mus musculus/domesticus
Length: 2332  
Fragment?: false
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Protein
E9PY55
Organism: Mus musculus/domesticus
Length: 2468  
Fragment?: false
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Protein
Q05CF0
Organism: Mus musculus/domesticus
Length: 518  
Fragment?: true
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Protein
F8VQL9
Organism: Mus musculus/domesticus
Length: 2507  
Fragment?: false
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Protein
Q5PRE9
Organism: Mus musculus/domesticus
Length: 2387  
Fragment?: false
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Protein
Q5RIM6
Organism: Mus musculus/domesticus
Length: 2454  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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