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Search results 1 to 96 out of 96 for Gps2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: G protein pathway suppressor 2 is involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this protein could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this protein may be signal repression []. This protein is a component of the N-CoR-HDAC3 []and also the SMRT corepressor complexes [].
Publication
First Author: Drareni K
Year: 2020
Journal: Cell Rep
Title: Adipocyte Reprogramming by the Transcriptional Coregulator GPS2 Impacts Beta Cell Insulin Secretion.
Volume: 32
Issue: 11
Pages: 108141
Publication
First Author: Ma WB
Year: 2020
Journal: Blood
Title: GPS2 promotes erythroid differentiation by control of the stability of EKLF protein.
Volume: 135
Issue: 25
Pages: 2302-2315
Publication
First Author: Cardamone MD
Year: 2018
Journal: Mol Cell
Title: Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation.
Volume: 69
Issue: 5
Pages: 757-772.e7
Publication
First Author: Drareni K
Year: 2018
Journal: Cell Rep
Title: GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation.
Volume: 24
Issue: 11
Pages: 2957-2971.e6
Publication
First Author: Cederquist CT
Year: 2017
Journal: Mol Metab
Title: Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue.
Volume: 6
Issue: 1
Pages: 125-137
Publication
First Author: Liang N
Year: 2019
Journal: Nat Commun
Title: Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Volume: 10
Issue: 1
Pages: 1684
Publication
First Author: Lentucci C
Year: 2017
Journal: J Biol Chem
Title: Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development.
Volume: 292
Issue: 7
Pages: 2754-2772
Publication
First Author: Huang Z
Year: 2021
Journal: Mol Cell
Title: The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.
Volume: 81
Issue: 5
Pages: 953-968.e9
Publication
First Author: Fan R
Year: 2016
Journal: Nat Med
Title: Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.
Volume: 22
Issue: 7
Pages: 780-91
Publication
First Author: Zhang J
Year: 2002
Journal: Mol Cell
Title: The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.
Volume: 9
Issue: 3
Pages: 611-23
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
Publication
First Author: Spain BH
Year: 1996
Journal: Mol Cell Biol
Title: Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.
Volume: 16
Issue: 12
Pages: 6698-706
Publication
First Author: Cheng X
Year: 2009
Journal: J Biol Chem
Title: G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.
Volume: 284
Issue: 52
Pages: 36395-404
Publication
First Author: Cardamone MD
Year: 2014
Journal: Cell Rep
Title: GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ.
Volume: 8
Issue: 1
Pages: 163-76
Publication
First Author: Guo C
Year: 2015
Journal: J Biol Chem
Title: The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor γ requires G protein pathway suppressor 2.
Volume: 290
Issue: 6
Pages: 3666-79
Publication
First Author: Cardamone MD
Year: 2012
Journal: Mol Cell
Title: A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.
Volume: 46
Issue: 1
Pages: 91-104
Publication
First Author: Liu XF
Year: 2012
Journal: PLoS One
Title: ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.
Volume: 7
Issue: 5
Pages: e38130
Publication
First Author: Huang Z
Year: 2019
Journal: FASEB J
Title: G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.
Volume: 33
Issue: 2
Pages: 1631-1643
Publication
First Author: Huang J
Year: 2015
Journal: J Biol Chem
Title: Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.
Volume: 290
Issue: 31
Pages: 19044-54
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication    
First Author: Gao Y
Year: 1999
Journal: GenBank Submission
Title: Mus musculus G protein pathway suppressor 2 mRNA, complete cds
Pages: AF153696
Publication
First Author: Venteclef N
Year: 2010
Journal: Genes Dev
Title: GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.
Volume: 24
Issue: 4
Pages: 381-95
Publication
First Author: Zhang D
Year: 2008
Journal: J Biol Chem
Title: G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.
Volume: 283
Issue: 13
Pages: 8580-90
Publication
First Author: Ishizuka T
Year: 2005
Journal: Mol Endocrinol
Title: The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.
Volume: 19
Issue: 6
Pages: 1443-51
Publication
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Sanyal S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.
Volume: 104
Issue: 40
Pages: 15665-70
Allele
Name: G protein pathway suppressor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
Protein Domain
Type: Domain
Description: The G-protein pathway suppressor 2 (GPS2)-interacting domain is found in NCoR (nuclear receptor corepressor) proteins. NCoR1 and NCoR2 (also known as SMRT) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways [].
Publication
First Author: Thiagarajan D
Year: 2016
Journal: Cell Rep
Title: Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.
Volume: 15
Issue: 1
Pages: 181-96
Protein
Organism: Mus musculus/domesticus
Length: 2453  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2472  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2473  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2386  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 791  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2332  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2468  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 518  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2507  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2387  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2454  
Fragment?: false