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Search results 1 to 100 out of 355 for Grk2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Hughes RJ
Year: 1996
Journal: Am J Physiol
Title: Cloning of GRK2 cDNA from S49 murine lymphoma cells.
Volume: 270
Issue: 3 Pt 1
Pages: C885-91
Publication    
First Author: Woodall BP
Year: 2019
Journal: JCI Insight
Title: Alteration of myocardial GRK2 produces a global metabolic phenotype.
Volume: 5
Publication
First Author: Daigle TL
Year: 2014
Journal: Neuropsychopharmacology
Title: Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission.
Volume: 39
Issue: 10
Pages: 2450-62
Publication
First Author: Shahid G
Year: 2007
Journal: J Biol Chem
Title: GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells.
Volume: 282
Issue: 28
Pages: 20612-20
Publication  
First Author: Thapaliya M
Year: 2023
Journal: Front Immunol
Title: GRK2 differentially regulates FcεRI and MRGPRB2-mediated responses in mast cells.
Volume: 14
Pages: 1155777
Publication
First Author: Sanchez-Perez A
Year: 2007
Journal: Biochem Biophys Res Commun
Title: GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2.
Volume: 359
Issue: 3
Pages: 611-5
Publication
First Author: Adler AJ
Year: 2020
Journal: Oncogene
Title: GRK2 enforces androgen receptor dependence in the prostate and prostate tumors.
Volume: 39
Issue: 11
Pages: 2424-2436
Publication  
First Author: Nijboer CH
Year: 2013
Journal: Neurobiol Dis
Title: Astrocyte GRK2 as a novel regulator of glutamate transport and brain damage.
Volume: 54
Pages: 206-15
Publication
First Author: Woodall MC
Year: 2016
Journal: Circ Res
Title: Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion Injury.
Volume: 119
Issue: 10
Pages: 1116-1127
Publication
First Author: Vila-Bedmar R
Year: 2012
Journal: FASEB J
Title: GRK2 contribution to the regulation of energy expenditure and brown fat function.
Volume: 26
Issue: 8
Pages: 3503-14
Publication  
First Author: Tao J
Year: 2023
Journal: Biomed Pharmacother
Title: A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation.
Volume: 157
Pages: 113997
Publication
First Author: Taguchi K
Year: 2017
Journal: Sci Rep
Title: Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis.
Volume: 7
Issue: 1
Pages: 8436
Publication
First Author: Sato PY
Year: 2015
Journal: J Mol Cell Cardiol
Title: GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels.
Volume: 89
Issue: Pt B
Pages: 360-4
Publication
First Author: Vila-Bedmar R
Year: 2020
Journal: Cell Mol Life Sci
Title: GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity.
Volume: 77
Issue: 23
Pages: 4957-4976
Publication
First Author: Snyder J
Year: 2021
Journal: Sci Rep
Title: GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells.
Volume: 11
Issue: 1
Pages: 11129
Publication
First Author: Tutunea-Fatan E
Year: 2018
Journal: Sci Rep
Title: GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation.
Volume: 8
Issue: 1
Pages: 11415
Publication
First Author: Tutunea-Fatan E
Year: 2015
Journal: J Biol Chem
Title: GRK2 targeted knock-down results in spontaneous hypertension, and altered vascular GPCR signaling.
Volume: 290
Issue: 8
Pages: 5141-5155
Publication
First Author: Mehta N
Year: 2015
Journal: Cell Rep
Title: GRK2 Fine-Tunes Circadian Clock Speed and Entrainment via Transcriptional and Post-translational Control of PERIOD Proteins.
Volume: 12
Issue: 8
Pages: 1272-88
Publication
First Author: Daigle TL
Year: 2012
Journal: J Neurosci
Title: Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation.
Volume: 32
Issue: 33
Pages: 11461-6
Publication
First Author: Nijboer CH
Year: 2010
Journal: Brain Behav Immun
Title: Cell-specific roles of GRK2 in onset and severity of hypoxic-ischemic brain damage in neonatal mice.
Volume: 24
Issue: 3
Pages: 420-6
Publication
First Author: Vroon A
Year: 2004
Journal: J Leukoc Biol
Title: Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4.
Volume: 75
Issue: 5
Pages: 901-9
Publication
First Author: Wang Y
Year: 2008
Journal: J Biol Chem
Title: Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.
Volume: 283
Issue: 4
Pages: 1799-807
Publication  
First Author: Yang X
Year: 2019
Journal: Cells
Title: GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
Volume: 8
Issue: 12
Publication
First Author: Schumacher SM
Year: 2016
Journal: Sci Signal
Title: A peptide of the RGS domain of GRK2 binds and inhibits Gα(q) to suppress pathological cardiac hypertrophy and dysfunction.
Volume: 9
Issue: 420
Pages: ra30
Publication
First Author: Willemen HL
Year: 2010
Journal: Pain
Title: Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.
Volume: 150
Issue: 3
Pages: 550-60
Publication
First Author: Eijkelkamp N
Year: 2010
Journal: J Neurosci
Title: Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.
Volume: 30
Issue: 38
Pages: 12806-15
Publication
First Author: Lymperopoulos A
Year: 2010
Journal: J Biol Chem
Title: Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction.
Volume: 285
Issue: 21
Pages: 16378-86
Publication
First Author: Keys JR
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1.
Volume: 285
Issue: 5
Pages: H2201-11
Publication
First Author: Ciccarelli M
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species.
Volume: 33
Issue: 10
Pages: 2415-24
Publication
First Author: Penela P
Year: 2008
Journal: EMBO J
Title: G protein-coupled receptor kinase 2 positively regulates epithelial cell migration.
Volume: 27
Issue: 8
Pages: 1206-18
Publication
First Author: Sefton M
Year: 2000
Journal: Mech Dev
Title: Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis.
Volume: 98
Issue: 1-2
Pages: 127-31
Publication
First Author: Penela P
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression.
Volume: 107
Issue: 3
Pages: 1118-23
Publication
First Author: Fu X
Year: 2013
Journal: J Biol Chem
Title: Inhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway.
Volume: 288
Issue: 11
Pages: 7738-7755
Publication
First Author: Sexton TJ
Year: 2015
Journal: PLoS One
Title: G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells.
Volume: 10
Issue: 6
Pages: e0128690
Publication
First Author: Schlegel P
Year: 2017
Journal: PLoS One
Title: G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.
Volume: 12
Issue: 7
Pages: e0182110
Publication
First Author: Vila-Bedmar R
Year: 2015
Journal: Sci Signal
Title: Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2.
Volume: 8
Issue: 386
Pages: ra73
Publication
First Author: Kleibeuker W
Year: 2007
Journal: Eur J Neurosci
Title: A role for G protein-coupled receptor kinase 2 in mechanical allodynia.
Volume: 25
Issue: 6
Pages: 1696-704
Publication
First Author: Vroon A
Year: 2005
Journal: J Immunol
Title: G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis.
Volume: 174
Issue: 7
Pages: 4400-6
Publication
First Author: Garcia-Guerra L
Year: 2014
Journal: J Mol Cell Biol
Title: Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2.
Volume: 6
Issue: 4
Pages: 299-311
Publication
First Author: Nijboer CH
Year: 2008
Journal: J Neurosci
Title: Low endogenous G-protein-coupled receptor kinase 2 sensitizes the immature brain to hypoxia-ischemia-induced gray and white matter damage.
Volume: 28
Issue: 13
Pages: 3324-32
Publication
First Author: Steury MD
Year: 2017
Journal: Biochem J
Title: G-protein-coupled receptor kinase-2 is a critical regulator of TNFα signaling in colon epithelial cells.
Volume: 474
Issue: 14
Pages: 2301-2313
Publication
First Author: Subramanian H
Year: 2014
Journal: J Biol Chem
Title: Regulation of Fc∈RI signaling in mast cells by G protein-coupled receptor kinase 2 and its RH domain.
Volume: 289
Issue: 30
Pages: 20917-27
Publication
First Author: Wang L
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss.
Volume: 288
Issue: 4
Pages: E826-34
Publication
First Author: Jiménez-Sainz MC
Year: 2006
Journal: Mol Biol Cell
Title: G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits.
Volume: 17
Issue: 1
Pages: 25-31
Publication
First Author: Ciccarelli M
Year: 2011
Journal: Circulation
Title: G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.
Volume: 123
Issue: 18
Pages: 1953-62
Publication
First Author: Lafarga V
Year: 2012
Journal: EMBO J
Title: A novel GRK2/HDAC6 interaction modulates cell spreading and motility.
Volume: 31
Issue: 4
Pages: 856-69
Publication
First Author: Raake PW
Year: 2012
Journal: Circulation
Title: Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Volume: 125
Issue: 17
Pages: 2108-18
Publication  
First Author: Perdices-Lopez C
Year: 2022
Journal: Metabolism
Title: Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons.
Volume: 129
Pages: 155141
Publication
First Author: Chen M
Year: 2013
Journal: Circ Res
Title: Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.
Volume: 112
Issue: 8
Pages: 1121-34
Publication  
First Author: Pfleger J
Year: 2018
Journal: J Mol Cell Cardiol
Title: G protein-coupled receptor kinase 2 contributes to impaired fatty acid metabolism in the failing heart.
Volume: 123
Pages: 108-117
Publication
First Author: Lieu M
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging.
Volume: 318
Issue: 5
Pages: H1162-H1175
Publication
First Author: Neill JD
Year: 1996
Journal: Endocrinology
Title: Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic alpha T3-1 cell line.
Volume: 137
Issue: 9
Pages: 3942-7
Publication
First Author: Mundell SJ
Year: 1997
Journal: Mol Pharmacol
Title: A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.
Volume: 51
Issue: 6
Pages: 991-8
Publication
First Author: Singhmar P
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.
Volume: 113
Issue: 11
Pages: 3036-41
Publication
First Author: Walker JK
Year: 1999
Journal: Am J Physiol
Title: Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.
Volume: 276
Issue: 4 Pt 2
Pages: R1214-21
Publication
First Author: Woodall BP
Year: 2016
Journal: J Biol Chem
Title: Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy.
Volume: 291
Issue: 42
Pages: 21913-21924
Publication
First Author: Cohn HI
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction.
Volume: 295
Issue: 4
Pages: H1695-704
Publication
First Author: DeFord-Watts LM
Year: 2007
Journal: J Biol Chem
Title: The membrane-proximal portion of CD3 epsilon associates with the serine/threonine kinase GRK2.
Volume: 282
Issue: 22
Pages: 16126-34
Publication
First Author: Arnon TI
Year: 2011
Journal: Science
Title: GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood.
Volume: 333
Issue: 6051
Pages: 1898-903
Publication
First Author: Rivas V
Year: 2013
Journal: J Clin Invest
Title: Developmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2.
Volume: 123
Issue: 11
Pages: 4714-30
Publication
First Author: Matkovich SJ
Year: 2006
Journal: Circ Res
Title: Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling.
Volume: 99
Issue: 9
Pages: 996-1003
Publication
First Author: Taguchi K
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Dysfunction of endothelium-dependent relaxation to insulin via PKC-mediated GRK2/Akt activation in aortas of ob/ob mice.
Volume: 301
Issue: 2
Pages: H571-83
Publication
First Author: Lucas E
Year: 2014
Journal: Biochim Biophys Acta
Title: Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns.
Volume: 1842
Issue: 12 Pt A
Pages: 2448-56
Publication
First Author: Hwang IY
Year: 2019
Journal: J Immunol
Title: Biased S1PR1 Signaling in B Cells Subverts Responses to Homeostatic Chemokines, Severely Disorganizing Lymphoid Organ Architecture.
Volume: 203
Issue: 9
Pages: 2401-2414
Publication
First Author: Cruces-Sande M
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans.
Volume: 1864
Issue: 12
Pages: 3655-3667
Publication
First Author: Liu Z
Year: 2013
Journal: J Immunol
Title: TLR4 Signaling augments monocyte chemotaxis by regulating G protein-coupled receptor kinase 2 translocation.
Volume: 191
Issue: 2
Pages: 857-64
Publication
First Author: Wang Y
Year: 2015
Journal: Circulation
Title: G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart.
Volume: 131
Issue: 16
Pages: 1392-404
Publication
First Author: Wu AD
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: Opsin 3-Gαs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2.
Volume: 64
Issue: 1
Pages: 59-68
Publication
First Author: Evron T
Year: 2011
Journal: J Biol Chem
Title: Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling.
Volume: 286
Issue: 31
Pages: 27676-86
Publication
First Author: Raake PW
Year: 2008
Journal: Circ Res
Title: G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.
Volume: 103
Issue: 4
Pages: 413-22
Publication
First Author: Taguchi K
Year: 2012
Journal: Diabetes
Title: G protein-coupled receptor kinase 2, with β-arrestin 2, impairs insulin-induced Akt/endothelial nitric oxide synthase signaling in ob/ob mouse aorta.
Volume: 61
Issue: 8
Pages: 1978-85
Publication
First Author: Eijkelkamp N
Year: 2010
Journal: J Neurosci
Title: GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain.
Volume: 30
Issue: 6
Pages: 2138-49
Publication
First Author: Huang ZM
Year: 2013
Journal: Sci Signal
Title: Convergence of G protein-coupled receptor and S-nitrosylation signaling determines the outcome to cardiac ischemic injury.
Volume: 6
Issue: 299
Pages: ra95
Publication
First Author: Fan Q
Year: 2013
Journal: PLoS One
Title: Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.
Volume: 8
Issue: 6
Pages: e66234
Publication
First Author: Garcia-Guerra L
Year: 2010
Journal: Diabetes
Title: G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity.
Volume: 59
Issue: 10
Pages: 2407-17
Publication
First Author: Dal-Secco D
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase.
Volume: 313
Issue: 1
Pages: H149-H163
Publication
First Author: Xu G
Year: 2022
Journal: Sci Rep
Title: Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis.
Volume: 12
Issue: 1
Pages: 19772
Publication
First Author: Raghuwanshi SK
Year: 2012
Journal: J Immunol
Title: The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.
Volume: 189
Issue: 6
Pages: 2824-32
Publication
First Author: Dang VC
Year: 2009
Journal: J Neurosci
Title: Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.
Volume: 29
Issue: 10
Pages: 3322-7
Publication
First Author: Vasudevan NT
Year: 2013
Journal: Circulation
Title: Gβγ-independent recruitment of G-protein coupled receptor kinase 2 drives tumor necrosis factor α-induced cardiac β-adrenergic receptor dysfunction.
Volume: 128
Issue: 4
Pages: 377-87
Publication
First Author: Rajagopal K
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.
Volume: 103
Issue: 44
Pages: 16284-9
Publication
First Author: Patial S
Year: 2009
Journal: Biochem J
Title: G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα.
Volume: 425
Issue: 1
Pages: 169-78
Publication  
First Author: Franco A
Year: 2018
Journal: J Mol Cell Cardiol
Title: G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.
Volume: 121
Pages: 60-68
Publication
First Author: Qi X
Year: 2018
Journal: Diabetologia
Title: Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Volume: 61
Issue: 5
Pages: 1180-1192
Publication
First Author: Taguchi K
Year: 2012
Journal: Endocrinology
Title: Inhibitor of G protein-coupled receptor kinase 2 normalizes vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.
Volume: 153
Issue: 7
Pages: 2985-96
Publication  
First Author: Glaser KM
Year: 2022
Journal: Front Immunol
Title: Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.
Volume: 13
Pages: 1039803
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory