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Search results 1 to 97 out of 97 for Grxcr1

0.022s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Glutaredoxin domain-containing cysteine-rich protein 1 (GRXCR1) contains a region of similarity to glutaredoxin proteins and a cysteine-rich region at its C terminus. It may be involved in regulation of actin filament architecture in hair cell stereocilia []. Mutations of the GRXCR1 gene cause deafness, autosomal recessive, 25 (DFNB25) [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Odeh H
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse.
Volume: 86
Issue: 2
Pages: 148-60
Publication
First Author: Schraders M
Year: 2010
Journal: Am J Hum Genet
Title: Homozygosity mapping reveals mutations of GRXCR1 as a cause of autosomal-recessive nonsyndromic hearing impairment.
Volume: 86
Issue: 2
Pages: 138-47
Publication
First Author: Lorente-Cánovas B
Year: 2022
Journal: PLoS One
Title: Grxcr1 regulates hair bundle morphogenesis and is required for normal mechanoelectrical transduction in mouse cochlear hair cells.
Volume: 17
Issue: 3
Pages: e0261530
Protein
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 296  
Fragment?: false
Publication
First Author: Woolley GW
Year: 1945
Journal: J Hered
Title: Pirouetting mice.
Volume: 36
Issue: 9
Pages: 281-284
Publication  
First Author: Kohrman DC
Year: 1998
Journal: Hered Deaf News
Title: Genetic, functional, and morphological analysis of pirouette, a mouse neuroepithelial deafness mutant.
Volume: 15
Pages: 19
Publication
First Author: Beyer LA
Year: 2000
Journal: J Neurocytol
Title: Hair cells in the inner ear of the pirouette and shaker 2 mutant mice.
Volume: 29
Issue: 4
Pages: 227-40
Publication
First Author: Odeh H
Year: 2004
Journal: Audiol Neurootol
Title: Characterization of two transgene insertional mutations at pirouette, a mouse deafness locus.
Volume: 9
Issue: 5
Pages: 303-14
Publication
First Author: DEOL MS
Year: 1956
Journal: Proc R Soc Lond B Biol Sci
Title: The anatomy and development of the mutants pirouette, shaker-1 and waltzer in the mouse.
Volume: 145
Issue: 919
Pages: 206-13
Publication
First Author: Sidman M
Year: 1966
Journal: Exp Neurol
Title: Hearing and vision in neurological mutant mice: a method for their evaluation.
Volume: 16
Issue: 4
Pages: 377-402
Publication
First Author: Karolyi IJ
Year: 2003
Journal: Hum Mol Genet
Title: Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia.
Volume: 12
Issue: 21
Pages: 2797-805
Publication  
First Author: KOCHER W
Year: 1960
Journal: Z Vererbungsl
Title: [Studies on the genetics and pathology of the development of 8 labyrinth mutants (deaf-waltzer-shaker mutants) in the mouse (Mus musculus)].
Volume: 91
Pages: 114-40
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Gagnon LH
Year: 2010
Journal: MGI Direct Data Submission
Title: Spontaneous Mutations to Pirouette
Publication      
First Author: Gagnon LH
Year: 2010
Journal: MGI Direct Data Submission
Title: Molecular Analysis of the pi-4J Allele
Publication
First Author: Erven A
Year: 2002
Journal: Eur J Neurosci
Title: A novel stereocilia defect in sensory hair cells of the deaf mouse mutant Tasmanian devil.
Volume: 16
Issue: 8
Pages: 1433-41
GXD Expression    
Probe: MGI:7435040
Assay Type: RT-PCR
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728628
Stage: TS28
Assay Id: MGI:7435053
Age: postnatal day 90
Image: 9
Specimen Label: P90 +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7435040
Assay Type: RT-PCR
Annotation Date: 2023-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728628
Stage: TS28
Assay Id: MGI:7435053
Age: postnatal day 90
Image: 9
Specimen Label: P90 -/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1729323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_04
Specimen Label: euxassay_013101_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1858023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_05
Specimen Label: euxassay_013101_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1729323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_06
Specimen Label: euxassay_013101_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1858023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_06
Specimen Label: euxassay_013101_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1858023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_21
Specimen Label: euxassay_013101_21
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1858023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_22
Specimen Label: euxassay_013101_22
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4425469
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1858023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825248
Age: embryonic day 14.5
Image: euxassay_013101_23
Specimen Label: euxassay_013101_23
Detected: true
Specimen Num: 6
Publication
First Author: Liu C
Year: 2018
Journal: Cell Rep
Title: GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing.
Volume: 25
Issue: 5
Pages: 1268-1280.e4
Publication
First Author: DICKIE MM
Year: 1946
Journal: J Hered
Title: Linkage studies with the pirouette gene in the mouse.
Volume: 37
Issue: 11
Pages: 335-7
Publication
First Author: Hagiwara N
Year: 2003
Journal: Dev Biol
Title: Nonneuronal expression of the GABA(A) beta3 subunit gene is required for normal palate development in mice.
Volume: 254
Issue: 1
Pages: 93-101
Publication
First Author: Lane PW
Year: 1967
Journal: J Hered
Title: Linkage groups 3 and XVII in the mouse and the position of the light-ear locus.
Volume: 58
Issue: 1
Pages: 21-4
Publication
First Author: British Society of Audiology short papers meeting on experimental studies of hearing and deafness. Cambridge, UK, 22-23 September 1996. Hughes DC
Year: 1997
Journal: Br J Audiol
Title: British Society of Audiology short pMapping of the mouse alpha 9 acetylcholine receptor subunit.
Volume: 31
Issue: 2
Pages: 73-132 (84 Abstr.)
Publication
First Author: Rodríguez-de la Rosa L
Year: 2015
Journal: Hear Res
Title: Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays.
Volume: 330
Issue: Pt A
Pages: 62-77
Publication  
First Author: Bailey DW
Year: 1972
Journal: Mouse News Lett
Title: Located histocompatibility genes.
Volume: 47
Pages: 18
Publication  
First Author: Potter PK
Year: 2016
Journal: Nat Commun
Title: Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Volume: 7
Pages: 12444
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Avenarius MR
Year: 2012
Journal: PhD Thesis - University of Michigan
Title: The Glutaredoxin-like Cysteine-rich Family of Genes, Grxcr1 and Grxcr2, in Stereocilia Development and Function
DO Term
Allele  
Name: glutaredoxin, cysteine rich 1; pirouette
Allele Type: Spontaneous
Strain
Attribute String: mutant strain, spontaneous mutation, congenic
Strain
Attribute String: mutant stock, spontaneous mutation
Strain
Attribute String: congenic, mutant strain, spontaneous mutation
Genotype
Symbol: Grxcr1/Grxcr1
Background: involves: C3H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Grxcr1/Grxcr1
Background: B6.C3-Grxcr1/J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Avenarius MR
Year: 2018
Journal: PLoS One
Title: Grxcr2 is required for stereocilia morphogenesis in the cochlea.
Volume: 13
Issue: 8
Pages: e0201713