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Search results 1 to 95 out of 95 for Gsap

0.128s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Xu P
Year: 2021
Journal: J Exp Med
Title: GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
Volume: 218
Issue: 8
Publication
First Author: He G
Year: 2010
Journal: Nature
Title: Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
Volume: 467
Issue: 7311
Pages: 95-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_07
Specimen Label: euxassay_009382_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_08
Specimen Label: euxassay_009382_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_09
Specimen Label: euxassay_009382_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_17
Specimen Label: euxassay_009382_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_18
Specimen Label: euxassay_009382_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_19
Specimen Label: euxassay_009382_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_02
Specimen Label: euxassay_009382_02
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_03
Specimen Label: euxassay_009382_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_04
Specimen Label: euxassay_009382_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_05
Specimen Label: euxassay_009382_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_19
Specimen Label: euxassay_009382_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_20
Specimen Label: euxassay_009382_20
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_21
Specimen Label: euxassay_009382_21
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_22
Specimen Label: euxassay_009382_22
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_11
Specimen Label: euxassay_009382_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_14
Specimen Label: euxassay_009382_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_11
Specimen Label: euxassay_009382_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_12
Specimen Label: euxassay_009382_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_13
Specimen Label: euxassay_009382_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_06
Specimen Label: euxassay_009382_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_19
Specimen Label: euxassay_009382_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_08
Specimen Label: euxassay_009382_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_09
Specimen Label: euxassay_009382_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_10
Specimen Label: euxassay_009382_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_11
Specimen Label: euxassay_009382_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_12
Specimen Label: euxassay_009382_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_15
Specimen Label: euxassay_009382_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_16
Specimen Label: euxassay_009382_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_17
Specimen Label: euxassay_009382_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4422958
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827213
Age: embryonic day 14.5
Image: euxassay_009382_18
Specimen Label: euxassay_009382_18
Detected: true
Specimen Num: 17
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
Protein Domain
Type: Domain
Description: The gamma-secretase-activating protein (GSAP) family includes the mammalian GSAPs and the insect pigeon proteins (also known as linotte proteins). GSAP is a gamma-secretase regulator. It specifically activates the production of beta-amyloid protein through interactions with both gamma-secretase and its substrate, the amyloid precursor protein carboxy-terminal fragment (APP-CTF) []. This has led to interest in the protein as potential therapeutic target for the treatment of Alzheimer's disease []. Pigeon/linotte was initially identified as a gene that functions in adult Drosophila during associative learning [].This entry represents a domain found in the C-terminal of GSAP family members.
Protein
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: true
Publication
First Author: Bolwig GM
Year: 1995
Journal: Neuron
Title: Molecular cloning of linotte in Drosophila: a novel gene that functions in adults during associative learning.
Volume: 15
Issue: 4
Pages: 829-42
Protein
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
Protein Domain
Type: Family
Description: This entry represents the gamma-secretase-activating protein (GSAP) family, whose members include the mammalian GSAPs and the insect pigeon proteins (also known as linotte proteins). GSAP is a gamma-secretase regulator. It specifically activates the production of beta-amyloid protein through interactions with both gamma-secretase and its substrate, the amyloid precursor protein carboxy-terminal fragment (APP-CTF) []. This has led to interest in the protein as potential therapeutic target for the treatment of Alzheimer's disease []. Pigeon/linotte was initially identified as a gene that functions in adult Drosophila during associative learning [].
Publication
First Author: Teranishi Y
Year: 2015
Journal: FEBS J
Title: Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage.
Volume: 282
Issue: 17
Pages: 3438-51