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Search results 1 to 100 out of 330 for Gsdmd

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Type Details Score
Gene
79792 | GSDMD
Type: gene
Organism: human
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Gene
739712 | GSDMD
Type: gene
Organism: chimpanzee
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Gene
513939 | GSDMD
Type: gene
Organism: cattle
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Gene
697137 | GSDMD
Type: gene
Organism: macaque, rhesus
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Gene
315084 | Gsdmd
Type: gene
Organism: rat
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Gene
609395 | GSDMD
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1916396 | Gsdmd
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36217543 | J:330048
 
First Author: Ye X
Year: 2022
Journal: Front Immunol
Title: GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis.
Volume: 13
Pages: 893914
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Publication
32109412 | J:296118
First Author: Wang K
Year: 2020
Journal: Cell
Title: Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Volume: 180
Issue: 5
Pages: 941-955.e20
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Publication
26375003 | J:226781
First Author: Shi J
Year: 2015
Journal: Nature
Title: Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Volume: 526
Issue: 7575
Pages: 660-5
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Publication
37679766 | J:340546
First Author: Challa NVD
Year: 2023
Journal: J Neuroinflammation
Title: GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice.
Volume: 20
Issue: 1
Pages: 205
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Publication
27339137 | J:234332
First Author: Aglietti RA
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Volume: 113
Issue: 28
Pages: 7858-63
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Publication
31682173 | J:294327
First Author: Li Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Activation of GSDMD contributes to acute kidney injury induced by cisplatin.
Volume: 318
Issue: 1
Pages: F96-F106
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Publication
37865673 | J:342082
First Author: Harvest CK
Year: 2023
Journal: Nat Commun
Title: An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2.
Volume: 14
Issue: 1
Pages: 6686
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Publication
32303674 | J:329515
First Author: Li J
Year: 2020
Journal: Cell Death Dis
Title: Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia-reperfusion injury.
Volume: 11
Issue: 4
Pages: 244
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Publication
31670032 | J:310718
 
First Author: Luan J
Year: 2020
Journal: Biomaterials
Title: GSDMD membrane pore is critical for IL-1β release and antagonizing IL-1β by hepatocyte-specific nanobiologics is a promising therapeutics for murine alcoholic steatohepatitis.
Volume: 227
Pages: 119570
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Publication
31113851 | J:284443
 
First Author: Kayagaki N
Year: 2019
Journal: Sci Signal
Title: IRF2 transcriptionally induces GSDMD expression for pyroptosis.
Volume: 12
Issue: 582
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Publication
36166295 | J:331796
 
First Author: Ma N
Year: 2022
Journal: JCI Insight
Title: Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis.
Volume: 7
Issue: 21
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Publication
- | J:267555
     
First Author: Shi H
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gasder.
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Publication
18693275 | J:140319
First Author: Fujii T
Year: 2008
Journal: Genesis
Title: Gasdermin D (Gsdmd) is dispensable for mouse intestinal epithelium development.
Volume: 46
Issue: 8
Pages: 418-23
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Publication
29195811 | J:259899
First Author: Evavold CL
Year: 2018
Journal: Immunity
Title: The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Volume: 48
Issue: 1
Pages: 35-44.e6
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Publication
29576317 | J:296114
First Author: Liu Z
Year: 2018
Journal: Structure
Title: Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Volume: 26
Issue: 5
Pages: 778-784.e3
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Publication
32553275 | J:296122
First Author: Liu Z
Year: 2020
Journal: Immunity
Title: Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Volume: 53
Issue: 1
Pages: 106-114.e5
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Publication
36844454 | J:334452
First Author: Traughber CA
Year: 2023
Journal: iScience
Title: Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.
Volume: 26
Issue: 2
Pages: 106076
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Publication
36288704 | J:330610
First Author: Jiang Y
Year: 2022
Journal: Cell Rep
Title: Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade.
Volume: 41
Issue: 4
Pages: 111553
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Publication
36753047 | J:337009
First Author: Tanaka S
Year: 2023
Journal: Carcinogenesis
Title: Gasdermin D represses inflammation-induced colon cancer development by regulating apoptosis.
Volume: 44
Issue: 4
Pages: 341-349
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Publication
34289345 | J:316837
First Author: Evavold CL
Year: 2021
Journal: Cell
Title: Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.
Volume: 184
Issue: 17
Pages: 4495-4511.e19
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Publication
34492225 | J:321939
First Author: Luchetti G
Year: 2021
Journal: Cell Host Microbe
Title: Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.
Volume: 29
Issue: 10
Pages: 1521-1530.e10
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Publication
35794369 | J:341429
First Author: Chen W
Year: 2022
Journal: Nat Immunol
Title: Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion.
Volume: 23
Issue: 7
Pages: 1021-1030
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Publication
36322773 | J:333061
First Author: Hu Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11.
Volume: 119
Issue: 45
Pages: e2210809119
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Publication
31492850 | J:279354
First Author: Lu Y
Year: 2019
Journal: Nat Commun
Title: Caspase-11 signaling enhances graft-versus-host disease.
Volume: 10
Issue: 1
Pages: 4044
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Publication
37945599 | J:342413
First Author: Rosli S
Year: 2023
Journal: Cell Death Dis
Title: Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection.
Volume: 14
Issue: 11
Pages: 727
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Publication
36065376 | J:334997
 
First Author: Ma EB
Year: 2022
Journal: Mediators Inflamm
Title: Gasdermin D Deficiency Does Not Protect Mice from High-Fat Diet-Induced Glucose Intolerance and Adipose Tissue Inflammation.
Volume: 2022
Pages: 7853482
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Publication
35941120 | J:330783
First Author: Wang Y
Year: 2022
Journal: Cell Death Dis
Title: GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy.
Volume: 13
Issue: 8
Pages: 693
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Publication
32592165 | J:297562
First Author: Saeki A
Year: 2020
Journal: Immunology
Title: Gasdermin D-independent release of interleukin-1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides.
Volume: 161
Issue: 2
Pages: 114-122
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Publication
34721422 | J:312708
 
First Author: Gao H
Year: 2021
Journal: Front Immunol
Title: Dysregulated Microbiota-Driven Gasdermin D Activation Promotes Colitis Development by Mediating IL-18 Release.
Volume: 12
Pages: 750841
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Publication
36311722 | J:331559
 
First Author: Xu G
Year: 2022
Journal: Front Immunol
Title: Gasdermin D protects against Streptococcus equi subsp. zooepidemicus infection through macrophage pyroptosis.
Volume: 13
Pages: 1005925
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Publication
32820063 | J:296127
First Author: Humphries F
Year: 2020
Journal: Science
Title: Succination inactivates gasdermin D and blocks pyroptosis.
Volume: 369
Issue: 6511
Pages: 1633-1637
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Publication
30089254 | J:271305
First Author: Monteleone M
Year: 2018
Journal: Cell Rep
Title: Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Volume: 24
Issue: 6
Pages: 1425-1433
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Publication
35907404 | J:327629
First Author: Weindel CG
Year: 2022
Journal: Cell
Title: Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.
Volume: 185
Issue: 17
Pages: 3214-3231.e23
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Publication
34395445 | J:334451
 
First Author: Opoku E
Year: 2021
Journal: Front Cell Dev Biol
Title: Gasdermin D Mediates Inflammation-Induced Defects in Reverse Cholesterol Transport and Promotes Atherosclerosis.
Volume: 9
Pages: 715211
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Publication
31802832 | J:290121
First Author: Li H
Year: 2019
Journal: World J Gastroenterol
Title: Gasdermin D-mediated hepatocyte pyroptosis expands inflammatory responses that aggravate acute liver failure by upregulating monocyte chemotactic protein 1/CC chemokine receptor-2 to recruit macrophages.
Volume: 25
Issue: 44
Pages: 6527-6540
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Publication
33208362 | J:310296
 
First Author: Demarco B
Year: 2020
Journal: Sci Adv
Title: Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality.
Volume: 6
Issue: 47
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Publication
31216481 | J:282707
First Author: Burgener SS
Year: 2019
Journal: Cell Rep
Title: Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation.
Volume: 27
Issue: 12
Pages: 3646-3656.e5
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Publication
31467036 | J:282786
First Author: Li S
Year: 2019
Journal: J Exp Med
Title: Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.
Volume: 216
Issue: 11
Pages: 2562-2581
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Publication
33110056 | J:298974
First Author: Wiernicki B
Year: 2020
Journal: Cell Death Dis
Title: Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis.
Volume: 11
Issue: 10
Pages: 922
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Publication
32111733 | J:287627
First Author: Wang Z
Year: 2020
Journal: J Immunol
Title: Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo.
Volume: 204
Issue: 7
Pages: 1929-1942
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Publication
36373462 | J:332582
First Author: Liao Y
Year: 2023
Journal: EMBO J
Title: The Ras GTPase-activating-like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL-1β release via exosomes.
Volume: 42
Issue: 1
Pages: e110780
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Publication
36250416 | J:347436
First Author: Xie J
Year: 2023
Journal: Eur J Immunol
Title: GSDMD-mediated NETosis promotes the development of acute respiratory distress syndrome.
Volume: 53
Issue: 1
Pages: e2250011
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Publication
33441602 | J:300439
First Author: Estfanous S
Year: 2021
Journal: Sci Rep
Title: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.
Volume: 11
Issue: 1
Pages: 855
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Publication
- | J:311911
     
First Author: Eltobgy M
Year: 2021
Journal: bioRxiv
Title: Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis.
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Publication
36589684 | J:336793
 
First Author: Zhang Y
Year: 2022
Journal: Oxid Med Cell Longev
Title: Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD.
Volume: 2022
Pages: 8704016
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Publication
29539421 | J:270873
First Author: Kambara H
Year: 2018
Journal: Cell Rep
Title: Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Volume: 22
Issue: 11
Pages: 2924-2936
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Publication
31064994 | J:275572
First Author: Tsuchiya K
Year: 2019
Journal: Nat Commun
Title: Caspase-1 initiates apoptosis in the absence of gasdermin D.
Volume: 10
Issue: 1
Pages: 2091
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Publication
37327784 | J:338142
First Author: He K
Year: 2023
Journal: Cell
Title: Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
Volume: 186
Issue: 14
Pages: 3033-3048.e20
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Publication
32371889 | J:292082
First Author: Karmakar M
Year: 2020
Journal: Nat Commun
Title: N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.
Volume: 11
Issue: 1
Pages: 2212
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Publication
34678072 | J:312930
First Author: Zhang P
Year: 2021
Journal: Sci Adv
Title: NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice.
Volume: 7
Issue: 43
Pages: eabi9471
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Publication
33761363 | J:324672
First Author: Tsuchiya K
Year: 2021
Journal: Cell Rep
Title: Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes.
Volume: 34
Issue: 12
Pages: 108887
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Publication
33883744 | J:319941
First Author: Xia S
Year: 2021
Journal: Nature
Title: Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Volume: 593
Issue: 7860
Pages: 607-611
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Publication
32597834 | J:293960
First Author: Bulek K
Year: 2020
Journal: J Clin Invest
Title: Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis.
Volume: 130
Issue: 8
Pages: 4218-4234
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Publication
37056920 | J:347435
First Author: Zhu CL
Year: 2023
Journal: Int J Biol Sci
Title: PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy.
Volume: 19
Issue: 5
Pages: 1413-1429
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Publication
33064557 | J:311144
First Author: Liu H
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Volume: 319
Issue: 6
Pages: H1482-H1495
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Publication
26375259 | J:226780
First Author: Kayagaki N
Year: 2015
Journal: Nature
Title: Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Volume: 526
Issue: 7575
Pages: 666-71
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Publication
30361383 | J:268622
First Author: Orning P
Year: 2018
Journal: Science
Title: Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Volume: 362
Issue: 6418
Pages: 1064-1069
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Publication
31836429 | J:289063
First Author: Yang X
Year: 2019
Journal: Immunity
Title: Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure.
Volume: 51
Issue: 6
Pages: 983-996.e6
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Publication
31251782 | J:324736
First Author: Gonçalves AV
Year: 2019
Journal: PLoS Pathog
Title: Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Volume: 15
Issue: 6
Pages: e1007886
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Publication
29937272 | J:277094
First Author: Kang R
Year: 2018
Journal: Cell Host Microbe
Title: Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.
Volume: 24
Issue: 1
Pages: 97-108.e4
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Publication
30902848 | J:272519
     
First Author: Chen KW
Year: 2019
Journal: EMBO J
Title: Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
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Publication
30388107 | J:269307
First Author: Xiao J
Year: 2018
Journal: PLoS Biol
Title: Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.
Volume: 16
Issue: 11
Pages: e3000047
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Publication
35244027 | J:321888
   
First Author: Sun K
Year: 2022
Journal: Elife
Title: Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling.
Volume: 11
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Publication
31036765 | J:276859
First Author: Wang J
Year: 2019
Journal: J Immunol
Title: Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.
Volume: 202
Issue: 12
Pages: 3468-3473
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Publication
29108122 | J:337170
First Author: Khanova E
Year: 2018
Journal: Hepatology
Title: Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.
Volume: 67
Issue: 5
Pages: 1737-1753
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Publication
31405732 | J:297425
First Author: Miao N
Year: 2019
Journal: Kidney Int
Title: The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury.
Volume: 96
Issue: 5
Pages: 1105-1120
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Publication
32726624 | J:323547
First Author: de Vasconcelos NM
Year: 2020
Journal: Cell Rep
Title: An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
Volume: 32
Issue: 4
Pages: 107959
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Publication
32760056 | J:294734
First Author: Xiao J
Year: 2020
Journal: PLoS Biol
Title: Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
Volume: 18
Issue: 8
Pages: e3000807
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Publication
33721834 | J:339056
 
First Author: Wu M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: cGAS promotes sepsis in radiotherapy of cancer by up-regulating caspase-11 signaling.
Volume: 551
Pages: 86-92
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Publication
35749514 | J:338168
First Author: Yamagishi R
Year: 2022
Journal: Sci Immunol
Title: Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma.
Volume: 7
Issue: 72
Pages: eabl7209
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Publication
30404813 | J:268263
First Author: Zhu Q
Year: 2018
Journal: J Immunol
Title: Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida.
Volume: 201
Issue: 12
Pages: 3662-3668
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Publication
26611636 | J:229325
First Author: He WT
Year: 2015
Journal: Cell Res
Title: Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Volume: 25
Issue: 12
Pages: 1285-98
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Publication
32763970 | J:298138
First Author: Zheng M
Year: 2020
Journal: J Biol Chem
Title: Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Volume: 295
Issue: 41
Pages: 14040-14052
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Publication
31723262 | J:285940
First Author: Newton K
Year: 2019
Journal: Nature
Title: Activity of caspase-8 determines plasticity between cell death pathways.
Volume: 575
Issue: 7784
Pages: 679-682
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Publication
34648590 | J:313687
First Author: Bjanes E
Year: 2021
Journal: PLoS Pathog
Title: Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Volume: 17
Issue: 10
Pages: e1009967
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Protein Coding Gene
MGP_CAROLIEiJ_G0019898 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916396 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0021862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0021796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0022387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0020959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0021270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0019906 | -
Type: protein_coding_gene
Organism: Mus pahari
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•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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