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Search results 1 to 100 out of 1312 for Gsk3b

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: GSK3B is a serine/threonine kinase that regulates many biological processes such as muscle differentiation [], tau-microtubule interactions [], Wnt signalling []and epithelial-mesenchymal transition during embryonic development []. It has been implicated in various diseases such as diabetes, inflammation, cancer, Alzheimer's and bipolar disorder [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Protein
Organism: Mus musculus
Length: 420  
Fragment?: false
Publication
First Author: Litwiniuk A
Year: 2016
Journal: PLoS One
Title: FOXO1 and GSK-3β Are Main Targets of Insulin-Mediated Myogenesis in C2C12 Muscle Cells.
Volume: 11
Issue: 1
Pages: e0146726
Publication
First Author: Cho JH
Year: 2004
Journal: J Neurochem
Title: Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules.
Volume: 88
Issue: 2
Pages: 349-58
Publication
First Author: Yook JI
Year: 2005
Journal: J Biol Chem
Title: Wnt-dependent regulation of the E-cadherin repressor snail.
Volume: 280
Issue: 12
Pages: 11740-8
Publication
First Author: Zhou BP
Year: 2004
Journal: Nat Cell Biol
Title: Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition.
Volume: 6
Issue: 10
Pages: 931-40
Publication
First Author: Rayasam GV
Year: 2009
Journal: Br J Pharmacol
Title: Glycogen synthase kinase 3: more than a namesake.
Volume: 156
Issue: 6
Pages: 885-98
GXD Expression
Probe: MGI:6502586
Assay Type: RNA in situ
Annotation Date: 2021-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1859021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6502634
Age: embryonic day 13.5
Image: 4A Gsk3b WT
Note: Strongest expression in retinal ganglion cell layer.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6502586
Assay Type: RNA in situ
Annotation Date: 2021-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6502634
Age: embryonic day 13.5
Image: 4A Gsk3b Vax2-/-
Note: Expression lost specifically in the ventral retina.
Detected: true
Specimen Num: 2
Publication
First Author: Xing B
Year: 2018
Journal: Glia
Title: Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model.
Volume: 66
Issue: 9
Pages: 1999-2012
Protein
Organism: Mus musculus
Length: 92  
Fragment?: true
Protein
Organism: Mus musculus
Length: 433  
Fragment?: false
Protein
Organism: Mus musculus
Length: 420  
Fragment?: false
Publication
First Author: Jorge-Torres OC
Year: 2018
Journal: Cell Rep
Title: Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice.
Volume: 23
Issue: 6
Pages: 1665-1677
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Deák VA
Year: 2016
Journal: J Biol Chem
Title: The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice.
Volume: 291
Issue: 2
Pages: 681-90
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: Urbanska M
Year: 2019
Journal: EBioMedicine
Title: GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation.
Volume: 39
Pages: 377-387
Publication  
First Author: Shen W
Year: 2015
Journal: Nat Commun
Title: Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Volume: 6
Pages: 8372
Publication
First Author: Credle JJ
Year: 2015
Journal: Cell Death Differ
Title: GSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein.
Volume: 22
Issue: 5
Pages: 838-51
Publication  
First Author: Kondratiuk I
Year: 2013
Journal: Behav Brain Res
Title: Glycogen synthase kinase-3beta affects size of dentate gyrus and species-typical behavioral tasks in transgenic and knockout mice.
Volume: 248
Pages: 46-50
Publication
First Author: Spittaels K
Year: 2000
Journal: J Biol Chem
Title: Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.
Volume: 275
Issue: 52
Pages: 41340-9
Publication
First Author: Wakatsuki S
Year: 2011
Journal: Nat Cell Biol
Title: ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation.
Volume: 13
Issue: 12
Pages: 1415-23
Publication
First Author: Terwel D
Year: 2008
Journal: Am J Pathol
Title: Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.
Volume: 172
Issue: 3
Pages: 786-98
Publication
First Author: Latapy C
Year: 2012
Journal: Philos Trans R Soc Lond B Biol Sci
Title: Selective deletion of forebrain glycogen synthase kinase 3β reveals a central role in serotonin-sensitive anxiety and social behaviour.
Volume: 367
Issue: 1601
Pages: 2460-74
Publication
First Author: Gillespie JR
Year: 2013
Journal: Endocrinology
Title: GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span.
Volume: 154
Issue: 10
Pages: 3702-18
Publication
First Author: Kapoor M
Year: 2008
Journal: J Clin Invest
Title: GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Volume: 118
Issue: 10
Pages: 3279-90
Publication
First Author: Itoh S
Year: 2012
Journal: J Biol Chem
Title: GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation.
Volume: 287
Issue: 35
Pages: 29227-36
Publication
First Author: Monteiro da Rocha A
Year: 2015
Journal: Biol Reprod
Title: Loss of glycogen synthase kinase 3 isoforms during murine oocyte growth induces offspring cardiac dysfunction.
Volume: 92
Issue: 5
Pages: 127
Publication
First Author: Gillespie JR
Year: 2011
Journal: Endocrinology
Title: Deletion of glycogen synthase kinase-3β in cartilage results in up-regulation of glycogen synthase kinase-3α protein expression.
Volume: 152
Issue: 5
Pages: 1755-66
Publication
First Author: O'Brien WT
Year: 2011
Journal: J Clin Invest
Title: Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice.
Volume: 121
Issue: 9
Pages: 3756-62
Publication
First Author: Steuber-Buchberger P
Year: 2008
Journal: Genesis
Title: Simultaneous Cre-mediated conditional knockdown of two genes in mice.
Volume: 46
Issue: 3
Pages: 144-51
Publication  
First Author: Yang YL
Year: 2020
Journal: Int J Mol Sci
Title: miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
Volume: 21
Issue: 18
Publication  
First Author: Li J
Year: 2020
Journal: Front Mol Neurosci
Title: GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib.
Volume: 13
Pages: 81
Publication  
First Author: Ocasio JK
Year: 2019
Journal: Development
Title: GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma.
Volume: 146
Issue: 20
Publication  
First Author: Georgy SR
Year: 2015
Journal: J Natl Cancer Inst
Title: Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.
Volume: 107
Issue: 9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hoeflich KP
Year: 2000
Journal: Nature
Title: Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation.
Volume: 406
Issue: 6791
Pages: 86-90
Publication
First Author: Fullár A
Year: 2014
Journal: PLoS One
Title: Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3β pathways in vivo.
Volume: 9
Issue: 4
Pages: e93469
Publication
First Author: Ishizawa T
Year: 2003
Journal: Am J Pathol
Title: Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice.
Volume: 163
Issue: 3
Pages: 1057-67
Publication
First Author: Liu Y
Year: 2010
Journal: Diabetologia
Title: Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice.
Volume: 53
Issue: 12
Pages: 2600-10
Publication
First Author: Patel S
Year: 2008
Journal: Mol Cell Biol
Title: Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action.
Volume: 28
Issue: 20
Pages: 6314-28
Publication
First Author: Rockenstein E
Year: 2007
Journal: J Neurosci
Title: Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.
Volume: 27
Issue: 8
Pages: 1981-91
Publication
First Author: Li YC
Year: 2020
Journal: Biol Psychiatry
Title: Deletion of Glycogen Synthase Kinase-3β in D2 Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity.
Volume: 87
Issue: 8
Pages: 745-755
Publication
First Author: Lucas JJ
Year: 2001
Journal: EMBO J
Title: Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice.
Volume: 20
Issue: 1-2
Pages: 27-39
Publication
First Author: Fuster-Matanzo A
Year: 2013
Journal: Hum Mol Genet
Title: Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis.
Volume: 22
Issue: 7
Pages: 1300-15
Publication
First Author: Noble W
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.
Volume: 102
Issue: 19
Pages: 6990-5
Publication
First Author: Hirotani S
Year: 2007
Journal: Circ Res
Title: Inhibition of glycogen synthase kinase 3beta during heart failure is protective.
Volume: 101
Issue: 11
Pages: 1164-74
Publication
First Author: O'Brien WT
Year: 2004
Journal: J Neurosci
Title: Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium.
Volume: 24
Issue: 30
Pages: 6791-8
Publication  
First Author: Liz MA
Year: 2014
Journal: BMC Biol
Title: Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.
Volume: 12
Pages: 47
Publication
First Author: Hu X
Year: 2006
Journal: Immunity
Title: IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.
Volume: 24
Issue: 5
Pages: 563-74
Publication  
First Author: Lavoie J
Year: 2013
Journal: Behav Brain Res
Title: Glycogen synthase kinase-3β haploinsufficiency lengthens the circadian locomotor activity period in mice.
Volume: 253
Pages: 262-5
Publication
First Author: Yao XQ
Year: 2012
Journal: FEBS Lett
Title: Glycogen synthase kinase-3β regulates leucine-309 demethylation of protein phosphatase-2A via PPMT1 and PME-1.
Volume: 586
Issue: 16
Pages: 2522-8
Publication
First Author: Liu KJ
Year: 2007
Journal: Nature
Title: Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.
Volume: 446
Issue: 7131
Pages: 79-82
Publication
First Author: Kimura T
Year: 2008
Journal: PLoS One
Title: GSK-3beta is required for memory reconsolidation in adult brain.
Volume: 3
Issue: 10
Pages: e3540
Publication
First Author: Arioka M
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Acceleration of bone development and regeneration through the Wnt/β-catenin signaling pathway in mice heterozygously deficient for GSK-3β.
Volume: 440
Issue: 4
Pages: 677-82
Publication
First Author: Jurado-Arjona J
Year: 2016
Journal: J Biol Chem
Title: GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.
Volume: 291
Issue: 15
Pages: 8199-213
Publication
First Author: Ge Y
Year: 2011
Journal: Lab Invest
Title: Conditional ablation of glycogen synthase kinase 3β in postnatal mouse kidney.
Volume: 91
Issue: 1
Pages: 85-96
Publication
First Author: Howard C
Year: 2012
Journal: Kidney Int
Title: Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice.
Volume: 82
Issue: 9
Pages: 1000-9
Publication
First Author: Zhou W
Year: 2012
Journal: PLoS One
Title: The effects of glycogen synthase kinase-3beta in serotonin neurons.
Volume: 7
Issue: 8
Pages: e43262
Publication
First Author: Theeuwes WF
Year: 2017
Journal: Biochim Biophys Acta
Title: Inactivation of glycogen synthase kinase-3β (GSK-3β) enhances skeletal muscle oxidative metabolism.
Volume: 1863
Issue: 12
Pages: 3075-3086
Publication
First Author: Liu E
Year: 2017
Journal: Sci Rep
Title: GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory.
Volume: 7
Issue: 1
Pages: 5781
Publication
First Author: Pansters NA
Year: 2015
Journal: Biochim Biophys Acta
Title: Muscle-specific GSK-3β ablation accelerates regeneration of disuse-atrophied skeletal muscle.
Volume: 1852
Issue: 3
Pages: 490-506
Publication
First Author: Ding L
Year: 2017
Journal: J Pathol
Title: Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia.
Volume: 243
Issue: 1
Pages: 65-77
Publication
First Author: Zhou S
Year: 2016
Journal: J Am Soc Nephrol
Title: Genetic and Pharmacologic Targeting of Glycogen Synthase Kinase 3β Reinforces the Nrf2 Antioxidant Defense against Podocytopathy.
Volume: 27
Issue: 8
Pages: 2289-308
Publication
First Author: Li C
Year: 2016
Journal: J Pathol
Title: The β isoform of GSK3 mediates podocyte autonomous injury in proteinuric glomerulopathy.
Volume: 239
Issue: 1
Pages: 23-35
Publication  
First Author: Barr JL
Year: 2020
Journal: Neuroscience
Title: Glycogen Synthase Kinase 3β in the Ventral Hippocampus is Important for Cocaine Reward and Object Location Memory.
Volume: 425
Pages: 101-111
Publication
First Author: Shi X
Year: 2019
Journal: J Pharmacol Exp Ther
Title: Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory.
Volume: 371
Issue: 2
Pages: 339-347
Publication
First Author: Coba MP
Year: 2012
Journal: J Neurosci
Title: TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.
Volume: 32
Issue: 40
Pages: 13987-99
Publication
First Author: Jones K
Year: 2012
Journal: J Clin Invest
Title: GSK3β mediates muscle pathology in myotonic dystrophy.
Volume: 122
Issue: 12
Pages: 4461-72
Publication
First Author: Lim NK
Year: 2014
Journal: Hum Mol Genet
Title: Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.
Volume: 23
Issue: 15
Pages: 4051-63
Publication
First Author: Xu Z
Year: 2013
Journal: PLoS One
Title: Roles of GSK3β in odor habituation and spontaneous neural activity of the mouse olfactory bulb.
Volume: 8
Issue: 5
Pages: e63598
Publication
First Author: Wang Y
Year: 2009
Journal: Diabetes
Title: Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling.
Volume: 58
Issue: 6
Pages: 1391-402
Publication
First Author: Chen L
Year: 2012
Journal: PLoS One
Title: Inhibition of glycogen synthase kinase 3β ameliorates D-GalN/LPS-induced liver injury by reducing endoplasmic reticulum stress-triggered apoptosis.
Volume: 7
Issue: 9
Pages: e45202
Publication
First Author: Perez-Costas E
Year: 2010
Journal: PLoS One
Title: Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain.
Volume: 5
Issue: 1
Pages: e8911
Publication
First Author: Lappalainen S
Year: 2009
Journal: Clin Endocrinol (Oxf)
Title: LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children.
Volume: 70
Issue: 5
Pages: 725-31