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Search results 1 to 100 out of 223 for Gtse1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
51512 | GTSE1
Type: gene
Organism: human
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Gene
507901 | GTSE1
Type: gene
Organism: cattle
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Gene
425204 | GTSE1
Type: gene
Organism: chicken
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Gene
553652 | gtse1
Type: gene
Organism: zebrafish
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Gene
714207 | GTSE1
Type: gene
Organism: macaque, rhesus
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Gene
448634 | gtse1
Type: gene
Organism: frog, western clawed
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Gene
300126 | Gtse1
Type: gene
Organism: rat
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Gene
608855 | GTSE1
Type: gene
Organism: dog, domestic
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Gene
458984 | GTSE1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1352755 | Gtse1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR026659 | GTSE1
Type: Family
Description: G2 and S phase-expressed protein 1 (GTSE1) may be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis []. When overexpressed, GTSE1 delays G2/M phase progression [].
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Publication
9724637 | J:49836
First Author: Utrera R
Year: 1998
Journal: EMBO J
Title: A novel p53-inducible gene coding for a microtubule-localized protein with G2-phase-specific expression.
Volume: 17
Issue: 17
Pages: 5015-25
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Gene
150384 | GTSE1-DT
Type: gene
Organism: human
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Protein
Q8R080
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q542Q3
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Publication
20577264 | -
First Author: Liu XS
Year: 2010
Journal: EMBO Rep
Title: Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery.
Volume: 11
Issue: 8
Pages: 626-32
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Protein Coding Gene
MGP_CAROLIEiJ_G0020133 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1352755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021900 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020138 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021030 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10974554 | J:64241
First Author: Monte M
Year: 2000
Journal: Gene
Title: Cloning, chromosome mapping and functional characterization of a human homologue of murine gtse-1 (B99) gene.
Volume: 254
Issue: 1-2
Pages: 229-36
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GXD Expression
GXD Expression
   
Probe: MGI:7425122
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425172
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7425122
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425172
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre; Magoh lox/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7425122
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425172
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425122
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425172
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre; Eif4a3 lox/+
Detected: true
Specimen Num: 4
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Publication
27618312 | J:235650
First Author: Mao H
Year: 2016
Journal: PLoS Genet
Title: Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.
Volume: 12
Issue: 9
Pages: e1006282
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Publication
11423996 | J:70201
First Author: Kannan K
Year: 2001
Journal: Oncogene
Title: DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.
Volume: 20
Issue: 26
Pages: 3449-55
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Pathway
R-MMU-8852276 | The role of GTSE1 in G2/M progression after G2 checkpoint
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Protein Coding Gene
MGI:1932127 | Fkbpl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O35450
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein Domain
IPR026657 | DDA3/GTSE-1
Type: Family
Description: This is a family of phosphoproteins which includes proline/serine-rich coiled-coil protein 1 (PSRC1, also known as DDA3) and G2 and S phase-expressed protein 1 (GTSE1).DDA3 is a microtubule-destabilising protein that controls spindle dynamics and mitotic progression by regulating microtubule depolymerases, such as Kif2a and MCAK [, ]. Deletion of DDA3 causes spindle hyper-stabilisation, inter-kinectochore tension loss, chromosome congression defects. This leads to unaligned chromosomes at metaphase and the accumulation of CENP-E (a plus end-motor protein) at kinectochore in these chromosomes []. It has also been suggested that DDA3 may participate in p53/TP53-regulated growth suppression []. GTSE1 may be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis []. When overexpressed, GTSE1 delays G2/M phase progression [].
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Publication
12750368 | -
First Author: Monte M
Year: 2003
Journal: J Biol Chem
Title: The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function.
Volume: 278
Issue: 32
Pages: 30356-64
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Protein Domain
IPR032768 | GTSE1_N
Type: Domain
Description: This entry represents the N terminus of GTSE1 proteins. GTSE-1 (G2 and S phase-expressed-1) protein is specifically expressed during S and G2 phases of the cell cycle. It is mainly localised to the microtubules and when overexpressed delays the G2 to M transition. the full protein negatively regulates p53 transactivation function, protein levels, and p53-dependent apoptosis [, ]. This domain is found in eukaryotes, and is approximately 140 amino acids in length. There is a conserved FDFD sequence motif.
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Protein
Q9D0P7
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
A2AEF3
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Publication
10618717 | J:64940
First Author: Lo PK
Year: 1999
Journal: Oncogene
Title: Identification of a novel mouse p53 target gene DDA3.
Volume: 18
Issue: 54
Pages: 7765-74
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Protein
Q922A4
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Publication
18411309 | -
First Author: Jang CY
Year: 2008
Journal: J Cell Biol
Title: DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement.
Volume: 181
Issue: 2
Pages: 255-67
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Publication
21426902 | -
First Author: Jang CY
Year: 2011
Journal: Biochem Biophys Res Commun
Title: DDA3 associates with MCAK and controls chromosome congression.
Volume: 407
Issue: 3
Pages: 610-4
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Protein Coding Gene
MGI:88311 | Ccnb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P30276
Organism: Mus musculus/domesticus
Length: 398  
Fragment?: false
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Protein Coding Gene
MGI:104556 | Cdkn1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96247 | Hsp90ab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:891995 | Mapre1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P39689
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: false
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Protein
P11499
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
Q61166
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein Coding Gene
MGI:98834 | Trp53
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96250 | Hsp90aa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3588215 | Tubal3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107861 | Tubb2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88302 | Ccnb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915201 | Tubb6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107814 | Tubb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1095409 | Tuba1c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1858225 | Tuba8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97621 | Plk1
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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