| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
horse |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cat, domestic |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6190478 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table S2 - E13.5 - Gusb |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6190478 |
| Age: |
postnatal day 4 |
|
|
| Specimen Label: |
Table S2 - P4 - Gusb |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689419 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6190478 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S2 - E11.5 - Gusb |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689424 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:6190478 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Table S2 - E15.5 - Gusb |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689426 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6190478 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Table S2 - E18.5 - Gusb |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6190478 |
| Age: |
postnatal day 14 |
|
|
| Specimen Label: |
Table S2 - P14 - Gusb |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6174579 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6190478 |
| Age: |
postnatal day 28 |
|
|
| Specimen Label: |
Table S2 - P28 - Gusb |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ray J |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells. |
| Volume: |
48 |
| Issue: |
2 |
| Pages: |
248-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Daly TM |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease. |
| Volume: |
96 |
| Issue: |
5 |
| Pages: |
2296-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kyle JW |
| Year: |
1990 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene. |
| Volume: |
87 |
| Issue: |
10 |
| Pages: |
3914-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bramwell KK |
| Year: |
2014 |
| Journal: |
J Clin Invest |
| Title: |
Lysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity. |
| Volume: |
124 |
| Issue: |
1 |
| Pages: |
311-20 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
250
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
193
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Donsante A |
| Year: |
2001 |
| Journal: |
Gene Ther |
| Title: |
Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors. |
| Volume: |
8 |
| Issue: |
17 |
| Pages: |
1343-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frisella WA |
| Year: |
2001 |
| Journal: |
Mol Ther |
| Title: |
Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII. |
| Volume: |
3 |
| Issue: |
3 |
| Pages: |
351-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hofling AA |
| Year: |
2003 |
| Journal: |
Blood |
| Title: |
Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease. |
| Volume: |
101 |
| Issue: |
5 |
| Pages: |
2054-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yasue M |
| Year: |
1991 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids. |
| Volume: |
57 |
| Issue: |
2-3 |
| Pages: |
142-8 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gallagher PM |
| Year: |
1987 |
| Journal: |
Genomics |
| Title: |
DNA sequence variation within the beta-glucuronidase gene complex among inbred strains of mice. |
| Volume: |
1 |
| Issue: |
2 |
| Pages: |
145-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gallagher PM |
| Year: |
1988 |
| Journal: |
Genomics |
| Title: |
The complete nucleotide sequence of murine beta-glucuronidase mRNA and its deduced polypeptide. |
| Volume: |
2 |
| Issue: |
3 |
| Pages: |
215-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
D'Amore MA |
| Year: |
1988 |
| Journal: |
Biochemistry |
| Title: |
Complete sequence and organization of the murine beta-glucuronidase gene. |
| Volume: |
27 |
| Issue: |
18 |
| Pages: |
7131-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wawrzyniak CJ |
| Year: |
1989 |
| Journal: |
Mol Cell Biol |
| Title: |
DNA determinants of structural and regulatory variation within the murine beta-glucuronidase gene complex. |
| Volume: |
9 |
| Issue: |
9 |
| Pages: |
4074-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Funkenstein B |
| Year: |
1988 |
| Journal: |
Mol Cell Biol |
| Title: |
Genomic organization and sequence of the Gus-s alpha allele of the murine beta-glucuronidase gene. |
| Volume: |
8 |
| Issue: |
3 |
| Pages: |
1160-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sands MS |
| Year: |
1994 |
| Journal: |
J Clin Invest |
| Title: |
Enzyme replacement therapy for murine mucopolysaccharidosis type VII. |
| Volume: |
93 |
| Issue: |
6 |
| Pages: |
2324-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Woloszynek JC |
| Year: |
2004 |
| Journal: |
Biochem J |
| Title: |
Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII. |
| Volume: |
379 |
| Issue: |
Pt 2 |
| Pages: |
461-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Poorthuis BJ |
| Year: |
1994 |
| Journal: |
Pediatr Res |
| Title: |
Bone marrow transplantation has a significant effect on enzyme levels and storage of glycosaminoglycans in tissues and in isolated hepatocytes of mucopolysaccharidosis type VII mice. |
| Volume: |
36 |
| Issue: |
2 |
| Pages: |
187-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moullier P |
| Year: |
1993 |
| Journal: |
Nat Genet |
| Title: |
Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts. |
| Volume: |
4 |
| Issue: |
2 |
| Pages: |
154-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohashi T |
| Year: |
1997 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice. |
| Volume: |
94 |
| Issue: |
4 |
| Pages: |
1287-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freeman BJ |
| Year: |
1999 |
| Journal: |
Blood |
| Title: |
Behavior and therapeutic efficacy of beta-glucuronidase-positive mononuclear phagocytes in a murine model of mucopolysaccharidosis type VII. |
| Volume: |
94 |
| Issue: |
6 |
| Pages: |
2142-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang PL |
| Year: |
1993 |
| Journal: |
Neuroreport |
| Title: |
Behavioural abnormalities in a murine model of a human lysosomal storage disease. |
| Volume: |
4 |
| Issue: |
5 |
| Pages: |
507-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Snyder EY |
| Year: |
1995 |
| Journal: |
Nature |
| Title: |
Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain. |
| Volume: |
374 |
| Issue: |
6520 |
| Pages: |
367-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berry CL |
| Year: |
1994 |
| Journal: |
Lab Invest |
| Title: |
Pathology of the ear in murine mucopolysaccharidosis type VII. Morphologic correlates of hearing loss. |
| Volume: |
71 |
| Issue: |
3 |
| Pages: |
438-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skorupa AF |
| Year: |
1999 |
| Journal: |
Exp Neurol |
| Title: |
Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice. |
| Volume: |
160 |
| Issue: |
1 |
| Pages: |
17-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ghodsi A |
| Year: |
1999 |
| Journal: |
Exp Neurol |
| Title: |
Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer. |
| Volume: |
160 |
| Issue: |
1 |
| Pages: |
109-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Parente MK |
| Year: |
2016 |
| Journal: |
Mol Genet Metab |
| Title: |
Integrated analysis of proteome and transcriptome changes in the mucopolysaccharidosis type VII mouse hippocampus. |
| Volume: |
118 |
| Issue: |
1 |
| Pages: |
41-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohlemiller KK |
| Year: |
2002 |
| Journal: |
Hear Res |
| Title: |
Inner ear pathology in the mucopolysaccharidosis VII mouse. |
| Volume: |
169 |
| Issue: |
1-2 |
| Pages: |
69-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sferra TJ |
| Year: |
2000 |
| Journal: |
Hum Gene Ther |
| Title: |
Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
507-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stein CS |
| Year: |
1999 |
| Journal: |
J Virol |
| Title: |
Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII mice. |
| Volume: |
73 |
| Issue: |
4 |
| Pages: |
3424-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Monroy MA |
| Year: |
2002 |
| Journal: |
Bone |
| Title: |
Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease. |
| Volume: |
30 |
| Issue: |
2 |
| Pages: |
352-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sands MS |
| Year: |
1993 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII. |
| Volume: |
90 |
| Issue: |
14 |
| Pages: |
6567-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bastedo L |
| Year: |
1994 |
| Journal: |
J Clin Invest |
| Title: |
Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII. |
| Volume: |
94 |
| Issue: |
3 |
| Pages: |
1180-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wolfe JH |
| Year: |
1992 |
| Journal: |
Nat Genet |
| Title: |
Herpesvirus vector gene transfer and expression of beta-glucuronidase in the central nervous system of MPS VII mice. |
| Volume: |
1 |
| Issue: |
5 |
| Pages: |
379-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Casal ML |
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