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Search results 1 to 100 out of 177 for Gzma

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Metkar SS
Year: 2008
Journal: Immunity
Title: Human and mouse granzyme A induce a proinflammatory cytokine response.
Volume: 29
Issue: 5
Pages: 720-33
Publication
First Author: Santiago L
Year: 2020
Journal: Cell Rep
Title: Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.
Volume: 32
Issue: 1
Pages: 107847
Publication
First Author: van den Boogaard FE
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia.
Volume: 311
Issue: 2
Pages: L507-16
Publication
First Author: Velaga S
Year: 2015
Journal: PLoS One
Title: Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease.
Volume: 10
Issue: 4
Pages: e0124927
Publication
First Author: Eisert V
Year: 2002
Journal: Immunobiology
Title: The course of Leishmania major infection in mice lacking granzyme-mediated mechanisms.
Volume: 205
Issue: 3
Pages: 314-20
Publication
First Author: Zhu P
Year: 2009
Journal: Blood
Title: The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.
Volume: 114
Issue: 6
Pages: 1205-16
Publication
First Author: Hartmann W
Year: 2011
Journal: J Immunol
Title: A novel and divergent role of granzyme A and B in resistance to helminth infection.
Volume: 186
Issue: 4
Pages: 2472-81
Publication
First Author: Shresta S
Year: 1999
Journal: Immunity
Title: Granzyme A initiates an alternative pathway for granule-mediated apoptosis.
Volume: 10
Issue: 5
Pages: 595-605
Publication
First Author: Müllbacher A
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes.
Volume: 96
Issue: 24
Pages: 13950-5
Publication
First Author: Regner M
Year: 2009
Journal: J Immunol
Title: Cutting edge: rapid and efficient in vivo cytotoxicity by cytotoxic T cells is independent of granzymes A and B.
Volume: 183
Issue: 1
Pages: 37-40
Publication
First Author: Pardo J
Year: 2007
Journal: Cell Death Differ
Title: Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.
Volume: 14
Issue: 10
Pages: 1768-79
Publication  
First Author: Schanoski AS
Year: 2019
Journal: Front Immunol
Title: Granzyme A in Chikungunya and Other Arboviral Infections.
Volume: 10
Pages: 3083
Publication
First Author: Pardo J
Year: 2002
Journal: Eur J Immunol
Title: The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells.
Volume: 32
Issue: 7
Pages: 1980-5
Publication
First Author: Kaiserman D
Year: 2014
Journal: J Biol Chem
Title: Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.
Volume: 289
Issue: 13
Pages: 9408-17
Publication
First Author: Regner M
Year: 2011
Journal: PLoS One
Title: In vivo elimination of MHC-I-deficient lymphocytes by activated natural killer cells is independent of granzymes A and B.
Volume: 6
Issue: 8
Pages: e23252
Publication
First Author: Martin P
Year: 2005
Journal: Blood
Title: Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?
Volume: 106
Issue: 8
Pages: 2871-8
Publication
First Author: Simon MM
Year: 1997
Journal: J Exp Med
Title: In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells.
Volume: 186
Issue: 10
Pages: 1781-6
Publication
First Author: Pardo J
Year: 2004
Journal: J Cell Biol
Title: Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.
Volume: 167
Issue: 3
Pages: 457-68
Publication  
First Author: Shimizu K
Year: 2019
Journal: Front Immunol
Title: Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.
Volume: 10
Pages: 1450
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Ebnet K
Year: 1992
Journal: Genomics
Title: Organization of the gene encoding the mouse T-cell-specific serine proteinase "granzyme A".
Volume: 13
Issue: 3
Pages: 502-8
Publication
First Author: Hershberger RJ
Year: 1992
Journal: J Biol Chem
Title: Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides.
Volume: 267
Issue: 35
Pages: 25488-93
Publication
First Author: Gershenfeld HK
Year: 1986
Journal: Science
Title: Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
Volume: 232
Issue: 4752
Pages: 854-8
Publication
First Author: Ebnet K
Year: 1995
Journal: EMBO J
Title: Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.
Volume: 14
Issue: 17
Pages: 4230-9
Publication
First Author: Uranga S
Year: 2016
Journal: PLoS One
Title: Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo.
Volume: 11
Issue: 4
Pages: e0153028
Publication
First Author: Gershenfeld HK
Year: 1988
Journal: Proc Natl Acad Sci U S A
Title: Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease.
Volume: 85
Issue: 4
Pages: 1184-8
Publication
First Author: Seril DN
Year: 2002
Journal: Dig Dis Sci
Title: Dietary iron supplementation enhances DSS-induced colitis and associated colorectal carcinoma development in mice.
Volume: 47
Issue: 6
Pages: 1266-78
GXD Expression      
Probe: MGI:3655713
Assay Type: RT-PCR
Annotation Date: 2006-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752320
Stage: TS20
Assay Id: MGI:3655717
Age: embryonic day 12.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3655713
Assay Type: RT-PCR
Annotation Date: 2006-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752320
Stage: TS20
Assay Id: MGI:3655717
Age: embryonic day 12.5
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3655728
Assay Type: RNA in situ
Annotation Date: 2006-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185720
Pattern: Single cells
Stage: TS20
Assay Id: MGI:3655732
Age: embryonic day 12.5
Note: Expression is in scattered cells outside the thymic anlage.
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3655728
Assay Type: RNA in situ
Annotation Date: 2006-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752320
Pattern: Single cells
Stage: TS20
Assay Id: MGI:3655732
Age: embryonic day 12.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3655728
Assay Type: RNA in situ
Annotation Date: 2006-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752320
Stage: TS20
Assay Id: MGI:3655732
Age: embryonic day 12.5
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:361696
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825294
Age: embryonic day 14.5
Image: euxassay_002448_09
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:361696
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825294
Age: embryonic day 14.5
Image: euxassay_002448_10
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:361696
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825294
Age: embryonic day 14.5
Image: euxassay_002448_12
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:361696
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825294
Age: embryonic day 14.5
Image: euxassay_002448_13
Detected: true
Specimen Num: 4
Publication
First Author: Pasternack MS
Year: 1991
Journal: J Biol Chem
Title: Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro.
Volume: 266
Issue: 22
Pages: 14703-8
Publication
First Author: Shresta S
Year: 1997
Journal: J Biol Chem
Title: Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes.
Volume: 272
Issue: 32
Pages: 20236-44
Publication
First Author: Brunet JF
Year: 1986
Journal: Nature
Title: The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14.
Volume: 322
Issue: 6076
Pages: 268-71
Publication
First Author: Müllbacher A
Year: 1999
Journal: J Virol
Title: Perforin is essential for control of ectromelia virus but not related poxviruses in mice.
Volume: 73
Issue: 2
Pages: 1665-7
Publication
First Author: Bem RA
Year: 2010
Journal: J Immunol
Title: Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice.
Volume: 184
Issue: 2
Pages: 931-8
Publication
First Author: Waterhouse NJ
Year: 2006
Journal: J Cell Biol
Title: Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.
Volume: 173
Issue: 1
Pages: 133-44
Publication
First Author: Bian G
Year: 2013
Journal: J Immunol
Title: Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect.
Volume: 190
Issue: 3
Pages: 1341-50
Publication
First Author: Mollah ZUA
Year: 2017
Journal: Diabetes
Title: Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
Volume: 66
Issue: 12
Pages: 3041-3050
Publication
First Author: Smyth MJ
Year: 1995
Journal: Immunol Today
Title: Granzymes: exogenous proteinases that induce target cell apoptosis.
Volume: 16
Issue: 4
Pages: 202-6
Publication
First Author: Kaiserman D
Year: 2006
Journal: J Cell Biol
Title: The major human and mouse granzymes are structurally and functionally divergent.
Volume: 175
Issue: 4
Pages: 619-30
Publication
First Author: Carrero JA
Year: 2008
Journal: J Immunol
Title: Granzymes drive a rapid listeriolysin O-induced T cell apoptosis.
Volume: 181
Issue: 2
Pages: 1365-74
Publication
First Author: Hoves S
Year: 2011
Journal: J Immunol
Title: A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.
Volume: 187
Issue: 3
Pages: 1166-75
Publication
First Author: Cao X
Year: 2007
Journal: Immunity
Title: Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
Volume: 27
Issue: 4
Pages: 635-46
Publication
First Author: Goping IS
Year: 2008
Journal: Blood
Title: Cytotoxic T lymphocytes overcome Bcl-2 inhibition: target cells contribute to their own demise.
Volume: 111
Issue: 4
Pages: 2142-51
Publication
First Author: Halloran PF
Year: 2004
Journal: Am J Transplant
Title: Lesions of T-cell-mediated kidney allograft rejection in mice do not require perforin or granzymes A and B.
Volume: 4
Issue: 5
Pages: 705-12
Publication
First Author: Wilson JA
Year: 2017
Journal: PLoS Pathog
Title: RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation.
Volume: 13
Issue: 2
Pages: e1006155
Publication
First Author: Jaime-Sánchez P
Year: 2018
Journal: Cell Death Differ
Title: Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.
Volume: 25
Issue: 9
Pages: 1536-1548
Publication
First Author: Wang Y
Year: 2004
Journal: Immunol Cell Biol
Title: Exocytosis and Fas mediated cytolytic mechanisms exert protection from West Nile virus induced encephalitis in mice.
Volume: 82
Issue: 2
Pages: 170-3
Publication
First Author: van Dommelen SL
Year: 2006
Journal: Immunity
Title: Perforin and granzymes have distinct roles in defensive immunity and immunopathology.
Volume: 25
Issue: 5
Pages: 835-48
Publication
First Author: Smyth MJ
Year: 2003
Journal: J Immunol
Title: Cutting edge: granzymes A and B are not essential for perforin-mediated tumor rejection.
Volume: 171
Issue: 2
Pages: 515-8
Publication
First Author: Susanto O
Year: 2013
Journal: Cell Death Differ
Title: Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis.
Volume: 20
Issue: 9
Pages: 1183-93
Publication
First Author: Chaudhri G
Year: 2015
Journal: J Virol
Title: Vaccine-induced protection against orthopoxvirus infection is mediated through the combined functions of CD4 T cell-dependent antibody and CD8 T cell responses.
Volume: 89
Issue: 3
Pages: 1889-99
Publication
First Author: Fehniger TA
Year: 2007
Journal: Immunity
Title: Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.
Volume: 26
Issue: 6
Pages: 798-811
Publication
First Author: Sutton VR
Year: 2007
Journal: J Cell Biol
Title: Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.
Volume: 176
Issue: 4
Pages: 425-33
Publication
First Author: Catalán E
Year: 2015
Journal: J Biol Chem
Title: Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.
Volume: 290
Issue: 11
Pages: 6868-77
Publication
First Author: Zhang M
Year: 2006
Journal: Immunity
Title: Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules.
Volume: 24
Issue: 4
Pages: 451-61
Publication
First Author: Lee WY
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia.
Volume: 111
Issue: 38
Pages: 13936-41
Publication  
First Author: Bunker LE Jr
Year: 1959
Journal: J Hered
Title: Hepatic fusion, a new gene in linkage group I of the mouse.
Volume: 50
Pages: 40-44
Publication
First Author: Held W
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.
Volume: 87
Issue: 6
Pages: 2239-43
Publication
First Author: Mueller C
Year: 1995
Journal: Diabetes
Title: Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates.
Volume: 44
Issue: 1
Pages: 112-7
Publication
First Author: Miura Y
Year: 1996
Journal: Genomics
Title: Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64).
Volume: 38
Issue: 3
Pages: 299-304
Publication  
First Author: Mattei MG
Year: 1987
Journal: Cytogenet Cell Genet
Title: In situ mapping of four cytotoxic T-lymphocyte associated proteins (CTLA) to the mouse genome.
Volume: 46
Pages: 657-658
Publication
First Author: Jenne D
Year: 1988
Journal: J Immunol
Title: cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes.
Volume: 140
Issue: 1
Pages: 318-23
Publication
First Author: Sutton VR
Year: 2016
Journal: FEBS J
Title: Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.
Volume: 283
Issue: 5
Pages: 947-61
Publication
First Author: Einecke G
Year: 2006
Journal: Am J Transplant
Title: Tubulitis and epithelial cell alterations in mouse kidney transplant rejection are independent of CD103, perforin or granzymes A/B.
Volume: 6
Issue: 9
Pages: 2109-20
Publication
First Author: Andoniou CE
Year: 2014
Journal: PLoS Pathog
Title: A natural genetic variant of granzyme B confers lethality to a common viral infection.
Volume: 10
Issue: 12
Pages: e1004526
Publication
First Author: Pao LI
Year: 2005
Journal: J Immunol
Title: Functional analysis of granzyme M and its role in immunity to infection.
Volume: 175
Issue: 5
Pages: 3235-43
Publication
First Author: Wang H
Year: 2018
Journal: Nat Commun
Title: MAIT cells protect against pulmonary Legionella longbeachae infection.
Volume: 9
Issue: 1
Pages: 3350
Publication
First Author: Sipione S
Year: 2005
Journal: J Immunol
Title: Impaired cytolytic activity in calreticulin-deficient CTLs.
Volume: 174
Issue: 6
Pages: 3212-9
Publication
First Author: Herda S
Year: 2012
Journal: Immunity
Title: The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
Volume: 37
Issue: 5
Pages: 854-66
Publication
First Author: Douville P
Year: 1992
Journal: Genomics
Title: Genetic mapping of the integrin alpha 1 gene (Vla1) to mouse chromosome 13.
Volume: 14
Issue: 2
Pages: 503-5
Publication
First Author: Louahed J
Year: 1995
Journal: J Immunol
Title: IL-9 induces expression of granzymes and high-affinity IgE receptor in murine T helper clones.
Volume: 154
Issue: 10
Pages: 5061-70
Publication
First Author: Pardo J
Year: 2009
Journal: PLoS One
Title: Caspase-dependent inhibition of mousepox replication by gzmB.
Volume: 4
Issue: 10
Pages: e7512
Publication
First Author: Masson D
Year: 1987
Journal: Cell
Title: A family of serine esterases in lytic granules of cytolytic T lymphocytes.
Volume: 49
Issue: 5
Pages: 679-85