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Search results 1 to 72 out of 72 for Gzmm

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3004 | GZMM
Type: gene
Organism: human
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Gene
512272 | GZMM
Type: gene
Organism: cattle
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Gene
101058016 | GZMM
Type: gene
Organism: chimpanzee
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Gene
100859124 | GZMM
Type: gene
Organism: chicken
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Gene
715031 | GZMM
Type: gene
Organism: macaque, rhesus
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Gene
29252 | Gzmm
Type: gene
Organism: rat
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Protein Coding Gene
MGI:99549 | Gzmm
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033040 | GZMM
Type: Family
Description: Granzyme M is a chymotrypsin-like serine protease that preferentially cuts its substrates after Met or Leu []. It has been shown to be involved in inflammation, tumour immunity and cell death [].
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Protein
B7ZP17
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
O08643
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q9R1W7
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Publication
20406824 | -
First Author: Hu D
Year: 2010
Journal: J Biol Chem
Title: Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells.
Volume: 285
Issue: 24
Pages: 18326-35
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Publication
25998963 | -
First Author: Voskoboinik I
Year: 2015
Journal: Nat Rev Immunol
Title: Perforin and granzymes: function, dysfunction and human pathology.
Volume: 15
Issue: 6
Pages: 388-400
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Publication
24625974 | J:302261
 
First Author: Baschuk N
Year: 2014
Journal: Cell Death Dis
Title: NK cell intrinsic regulation of MIP-1α by granzyme M.
Volume: 5
Pages: e1115
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Publication
16116214 | J:113213
First Author: Pao LI
Year: 2005
Journal: J Immunol
Title: Functional analysis of granzyme M and its role in immunity to infection.
Volume: 175
Issue: 5
Pages: 3235-43
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Protein Coding Gene
MGP_CAROLIEiJ_G0015535 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017431 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017188 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017288 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016564 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030948 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016353 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8781119 | J:35546
First Author: Kelly JM
Year: 1996
Journal: Immunogenetics
Title: Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.
Volume: 44
Issue: 5
Pages: 340-50
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Publication
21564021 | J:175094
First Author: de Poot SA
Year: 2011
Journal: Biochem J
Title: Human and mouse granzyme M display divergent and species-specific substrate specificities.
Volume: 437
Issue: 3
Pages: 431-42
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GXD Expression
GXD Expression
     
Probe: MGI:6444311
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444866
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444311
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444866
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7435629
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435665
Age: postnatal month 2
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7435629
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435665
Age: postnatal month 2
Specimen Label: Nrl<-/->
Detected: true
Specimen Num: 2
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Publication
25526309 | J:302262
First Author: Prakash MD
Year: 2014
Journal: Immunity
Title: Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.
Volume: 41
Issue: 6
Pages: 960-72
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Publication
20585036 | J:162467
First Author: Anthony DA
Year: 2010
Journal: J Immunol
Title: A role for granzyme M in TLR4-driven inflammation and endotoxicosis.
Volume: 185
Issue: 3
Pages: 1794-803
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Publication
24487434 | J:208773
First Author: Afshar-Sterle S
Year: 2014
Journal: Nat Med
Title: Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas.
Volume: 20
Issue: 3
Pages: 283-90
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Publication
7713495 | J:22325
First Author: Pilat D
Year: 1994
Journal: Genomics
Title: The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3.
Volume: 24
Issue: 3
Pages: 445-50
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Publication
15454490 | J:96611
First Author: Bots M
Year: 2005
Journal: Blood
Title: SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity.
Volume: 105
Issue: 3
Pages: 1153-61
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Publication
7806275 | J:22311
First Author: Thia KY
Year: 1995
Journal: Immunogenetics
Title: The natural killer cell serine protease gene Lmet1 maps to mouse chromosome 10.
Volume: 41
Issue: 1
Pages: 47-9
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Publication
10087299 | J:54120
First Author: Fletcher CF
Year: 1999
Journal: Mamm Genome
Title: Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals.
Volume: 10
Issue: 4
Pages: 390-6
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Publication
24906954 | J:320190
First Author: Liu T
Year: 2015
Journal: Mol Neurobiol
Title: A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome.
Volume: 51
Issue: 3
Pages: 1053-63
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Publication
10984455 | J:64475
First Author: Puttagunta R
Year: 2000
Journal: Genome Res
Title: Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.
Volume: 10
Issue: 9
Pages: 1369-80
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Publication
15163632 | J:225638
First Author: Yoshida S
Year: 2004
Journal: Hum Mol Genet
Title: Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
Volume: 13
Issue: 14
Pages: 1487-503
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Gzmm<tm1(cre)Mjs> | MGI:3665444
Name: granzyme M (lymphocyte met-ase 1); targeted mutation 1, Mark J Smyth
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:3687290 | C57BL/6-Gzmm<tm1(cre)Mjs>
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Gzmm/Gzmm
Background: C57BL/6-Gzmm
Zygosity: hm
Has Mutant Allele: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom