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Search results 1 to 100 out of 233 for H2-Aa

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0.016s
Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:1430461
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3825886
Age: embryonic day 14.5
Image: Additional file 4 H2-Aa
Specimen Label: Additional file 4 H2-Aa
Detected: false
Specimen Num: 1
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Chen YT
Year: 2018
Journal: J Immunol
Title: B Cell Development sans B Cell Receptor Responsiveness Due to Unfolded Protein Response-Triggered Mef2c Protein Degradation.
Volume: 201
Issue: 10
Pages: 2885-2898
Gene
Type: gene
Organism: frog, African clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Benoist CO
Year: 1983
Journal: Cell
Title: Regions of allelic hypervariability in the murine A alpha immune response gene.
Volume: 34
Issue: 1
Pages: 169-77
Publication
First Author: Acha-Orbea H
Year: 1991
Journal: Immunogenetics
Title: Nonobese diabetic and nonobese nondiabetic mice have unique MHC class II haplotypes.
Volume: 34
Issue: 1
Pages: 57-9
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Benoist CO
Year: 1983
Journal: Proc Natl Acad Sci U S A
Title: The murine Ia alpha chains, E alpha and A alpha, show a surprising degree of sequence homology.
Volume: 80
Issue: 2
Pages: 534-8
Publication
First Author: Robinson RR
Year: 1983
Journal: J Immunol
Title: Extensive polymorphism surrounding the murine Ia A beta chain gene.
Volume: 131
Issue: 4
Pages: 2025-31
Publication
First Author: Zhu Y
Year: 2003
Journal: J Mol Biol
Title: Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.
Volume: 326
Issue: 4
Pages: 1157-74
Publication
First Author: Bishop GA
Year: 1988
Journal: Immunogenetics
Title: Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes.
Volume: 28
Issue: 3
Pages: 184-92
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Acha-Orbea H
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.
Volume: 84
Issue: 8
Pages: 2435-9
Publication
First Author: Graser RT
Year: 1999
Journal: Immunogenetics
Title: MHC characterization of ALR and ALS mice: respective similarities to the NOD and NON strains.
Volume: 49
Issue: 7-8
Pages: 722-6
Protein
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: false
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Prochazka M
Year: 1989
Journal: Diabetes
Title: Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.
Volume: 38
Issue: 11
Pages: 1446-55
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Clausen BE
Year: 1999
Journal: Transgenic Res
Title: Conditional gene targeting in macrophages and granulocytes using LysMcre mice.
Volume: 8
Issue: 4
Pages: 265-77
Publication
First Author: Zelenay S
Year: 2012
Journal: J Clin Invest
Title: The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice.
Volume: 122
Issue: 5
Pages: 1615-27
Publication
First Author: Schriek P
Year: 2022
Journal: Science
Title: Marginal zone B cells acquire dendritic cell functions by trogocytosis.
Volume: 375
Issue: 6581
Pages: eabf7470
Publication
First Author: Irla M
Year: 2010
Journal: J Exp Med
Title: MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.
Volume: 207
Issue: 9
Pages: 1891-905
Publication
First Author: Pellefigues C
Year: 2021
Journal: J Allergy Clin Immunol
Title: Basophils promote barrier dysfunction and resolution in the atopic skin.
Volume: 148
Issue: 3
Pages: 799-812.e10
Publication
First Author: Kenty G
Year: 1998
Journal: J Immunol
Title: MHC class II expression in double mutant mice lacking invariant chain and DM functions.
Volume: 160
Issue: 2
Pages: 606-14
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Brentville VA
Year: 2019
Journal: Oncoimmunology
Title: T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy.
Volume: 8
Issue: 5
Pages: e1576490
Publication  
First Author: Brentville VA
Year: 2022
Journal: Front Immunol
Title: Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy.
Volume: 13
Pages: 1066185
Publication  
First Author: Choudhury RH
Year: 2022
Journal: J Immunother Cancer
Title: PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy.
Volume: 10
Issue: 2
Publication  
First Author: Cook K
Year: 2022
Journal: Front Immunol
Title: Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity.
Volume: 13
Pages: 873947
Publication      
First Author: Brentville VA
Year: 2021
Journal: bioRxiv
Title: A novel bivalent DNA vaccine encoding both spike protein receptor-binding domain and nucleocapsid protein of SARS-CoV-2 to elicit T cell and neutralising antibody responses that cross react with variants.
Publication
First Author: Choudhury RH
Year: 2023
Journal: Immunology
Title: Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool.
Volume: 169
Issue: 4
Pages: 467-486
Publication  
First Author: Symonds P
Year: 2021
Journal: Front Immunol
Title: Citrullinated Epitopes Identified on Tumour MHC Class II by Peptide Elution Stimulate Both Regulatory and Th1 Responses and Require Careful Selection for Optimal Anti-Tumour Responses.
Volume: 12
Pages: 764462
Publication
First Author: Ru Z
Year: 2012
Journal: PLoS One
Title: Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein.
Volume: 7
Issue: 3
Pages: e32247
Publication  
First Author: Cook KW
Year: 2021
Journal: J Immunother Cancer
Title: Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy.
Volume: 9
Issue: 7
Publication
First Author: Wiethe C
Year: 2007
Journal: J Immunol
Title: Interdependency of MHC class II/self-peptide and CD1d/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity.
Volume: 178
Issue: 8
Pages: 4908-16
Publication
First Author: Dubrot J
Year: 2014
Journal: J Exp Med
Title: Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance.
Volume: 211
Issue: 6
Pages: 1153-66
Publication
First Author: Panchanathan V
Year: 2006
Journal: J Virol
Title: Protective immunity against secondary poxvirus infection is dependent on antibody but not on CD4 or CD8 T-cell function.
Volume: 80
Issue: 13
Pages: 6333-8
Publication
First Author: Chen YT
Year: 2017
Journal: J Immunol
Title: Low-Level MHC Class II Expression Leads to Suboptimal Th Cell Response, Increased Autoaggression, and Heightened Cytokine Inducibility.
Volume: 198
Issue: 5
Pages: 1928-1943
Publication
First Author: Clausen BE
Year: 1998
Journal: Immunity
Title: Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice.
Volume: 8
Issue: 2
Pages: 143-55
Publication
First Author: Alsharifi M
Year: 2013
Journal: PLoS One
Title: MHC class II-alpha chain knockout mice support increased viral replication that is independent of their lack of MHC class II cell surface expression and associated immune function deficiencies.
Volume: 8
Issue: 6
Pages: e68458
Publication  
First Author: Daley SR
Year: 2013
Journal: Elife
Title: Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.
Volume: 2
Pages: e01020
Publication
First Author: Irla M
Year: 2012
Journal: PLoS One
Title: Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla.
Volume: 7
Issue: 12
Pages: e52591
Publication
First Author: Dominguez AL
Year: 2008
Journal: Cancer Res
Title: Implications of aging and self-tolerance on the generation of immune and antitumor immune responses.
Volume: 68
Issue: 13
Pages: 5423-31
Publication
First Author: McCoy KD
Year: 2006
Journal: Immunity
Title: Natural IgE production in the absence of MHC Class II cognate help.
Volume: 24
Issue: 3
Pages: 329-39
Publication
First Author: Bochtler P
Year: 2008
Journal: J Immunol
Title: Type I IFN-induced, NKT cell-mediated negative control of CD8 T cell priming by dendritic cells.
Volume: 181
Issue: 3
Pages: 1633-43
Publication
First Author: Hansen DS
Year: 2003
Journal: Eur J Immunol
Title: CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses.
Volume: 33
Issue: 9
Pages: 2588-98
Allele
Name: histocompatibility 2, class II antigen A, beta 1; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Koonce CH
Year: 2004
Journal: J Immunol
Title: Dissecting MHC class II export, B cell maturation, and DM stability defects in invariant chain mutant mice.
Volume: 173
Issue: 5
Pages: 3271-80
Publication
First Author: Kovats S
Year: 1998
Journal: J Exp Med
Title: Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo.
Volume: 187
Issue: 2
Pages: 245-51
Publication
First Author: Szeto C
Year: 2022
Journal: Nat Commun
Title: Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Volume: 13
Issue: 1
Pages: 4951
Publication
First Author: Wiesel M
Year: 2010
Journal: J Immunol
Title: Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses.
Volume: 185
Issue: 9
Pages: 5188-97
Publication
First Author: Hermans IF
Year: 1999
Journal: J Immunol
Title: Impaired ability of MHC class II-/- dendritic cells to provide tumor protection is rescued by CD40 ligation.
Volume: 163
Issue: 1
Pages: 77-81
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Publication
First Author: Marguerat S
Year: 1999
Journal: J Immunol
Title: Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin.
Volume: 163
Issue: 7
Pages: 4033-40
Publication
First Author: Schmedt C
Year: 2001
Journal: J Exp Med
Title: Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk).
Volume: 193
Issue: 7
Pages: 815-26
Publication
First Author: Flatz L
Year: 2010
Journal: PLoS Pathog
Title: T cell-dependence of Lassa fever pathogenesis.
Volume: 6
Issue: 3
Pages: e1000836
Publication  
First Author: Wirasinha RC
Year: 2021
Journal: J Exp Med
Title: Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
Volume: 218
Issue: 2
Publication
First Author: Wirasinha RC
Year: 2019
Journal: Cell Death Differ
Title: Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells.
Volume: 26
Issue: 12
Pages: 2727-2739
Publication
First Author: Kohli K
Year: 2016
Journal: Eur J Immunol
Title: Plasmacytoid dendritic cells induce tolerance predominantly by cargoing antigen to lymph nodes.
Volume: 46
Issue: 11
Pages: 2659-2668
Publication
First Author: Matthews KE
Year: 2007
Journal: J Immunol
Title: Increasing the survival of dendritic cells in vivo does not replace the requirement for CD4+ T cell help during primary CD8+ T cell responses.
Volume: 179
Issue: 9
Pages: 5738-47
Publication
First Author: Miyazaki T
Year: 1996
Journal: Cell
Title: Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway.
Volume: 84
Issue: 4
Pages: 531-41
Publication
First Author: Wilson KR
Year: 2018
Journal: PLoS One
Title: MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway.
Volume: 13
Issue: 7
Pages: e0200540
Publication
First Author: Lundberg K
Year: 1995
Journal: J Exp Med
Title: Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes.
Volume: 181
Issue: 5
Pages: 1643-51
Publication
First Author: Irla M
Year: 2008
Journal: Immunity
Title: Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.
Volume: 29
Issue: 3
Pages: 451-63
Publication
First Author: Fung-Leung WP
Year: 1996
Journal: Science
Title: Antigen presentation and T cell development in H2-M-deficient mice.
Volume: 271
Issue: 5253
Pages: 1278-81
Publication
First Author: Alfonso C
Year: 2001
Journal: J Immunol
Title: The impact of H2-DM on humoral immune responses.
Volume: 167
Issue: 11
Pages: 6348-55
Publication
First Author: Martin WD
Year: 1996
Journal: Cell
Title: H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection.
Volume: 84
Issue: 4
Pages: 543-50
Publication
First Author: Genton C
Year: 2006
Journal: J Immunol
Title: The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity.
Volume: 177
Issue: 4
Pages: 2285-93
Publication
First Author: Schuster C
Year: 2013
Journal: PLoS One
Title: A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
Volume: 8
Issue: 8
Pages: e71746
Allele
Name: histocompatibility 2, class II antigen A, alpha; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Inostroza-Nieves Y
Year: 2023
Journal: Front Immunol
Title: Blockade of endothelin-1 receptor B regulates molecules of the major histocompatibility complex in sickle cell disease.
Volume: 14
Pages: 1124269
Publication
First Author: MacKay PA
Year: 2006
Journal: Eur J Immunol
Title: Circulating, soluble forms of major histocompatibility complex antigens are not exosome-associated.
Volume: 36
Issue: 11
Pages: 2875-84
Publication
First Author: Carrasco-Marin E
Year: 1996
Journal: J Immunol
Title: The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders.
Volume: 156
Issue: 2
Pages: 450-8