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Search results 1 to 100 out of 1209 for Hand1

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3506465
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Male
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513123
Age: embryonic day 15.5
Image: 4 - Hand1
Specimen Label: 4 - Hand1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506465
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Male
Emaps: EMAPS:2869723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6513123
Age: embryonic day 15.5
Image: 4 - Hand1
Note: Expression is seen in discrete domains within medial urethral structures of the ejaculatory duct.
Specimen Label: 4 - Hand1
Detected: true
Specimen Num: 1
Publication
First Author: Risebro CA
Year: 2006
Journal: Development
Title: Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.
Volume: 133
Issue: 22
Pages: 4595-606
Publication
First Author: Firulli BA
Year: 2017
Journal: Development
Title: Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis.
Volume: 144
Issue: 13
Pages: 2480-2489
Publication
First Author: Martindill DM
Year: 2007
Journal: Nat Cell Biol
Title: Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.
Volume: 9
Issue: 10
Pages: 1131-41
Publication
First Author: Laurie LE
Year: 2016
Journal: PLoS One
Title: The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.
Volume: 11
Issue: 2
Pages: e0150263
Publication
First Author: Firulli BA
Year: 2014
Journal: Development
Title: Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis.
Volume: 141
Issue: 15
Pages: 3050-61
Publication
First Author: Firulli BA
Year: 2010
Journal: Dev Dyn
Title: Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability.
Volume: 239
Issue: 10
Pages: 2748-60
Publication
First Author: Yamada K
Year: 2006
Journal: Differentiation
Title: Sox15 enhances trophoblast giant cell differentiation induced by Hand1 in mouse placenta.
Volume: 74
Issue: 5
Pages: 212-21
Publication
First Author: Hu D
Year: 2013
Journal: Dev Biol
Title: The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer.
Volume: 382
Issue: 2
Pages: 470-81
Publication
First Author: Maska EL
Year: 2010
Journal: Genesis
Title: A Tlx2-Cre mouse line uncovers essential roles for hand1 in extraembryonic and lateral mesoderm.
Volume: 48
Issue: 8
Pages: 479-84
Publication  
First Author: Smart N
Year: 2002
Journal: Mech Dev
Title: A differential screen for putative targets of the bHLH transcription factor Hand1 in cardiac morphogenesis.
Volume: 119 Suppl 1
Pages: S65-71
Publication
First Author: Breckenridge RA
Year: 2009
Journal: J Mol Cell Cardiol
Title: Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice.
Volume: 47
Issue: 1
Pages: 133-41
Publication
First Author: Riley P
Year: 1998
Journal: Nat Genet
Title: The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis.
Volume: 18
Issue: 3
Pages: 271-5
Publication
First Author: Breckenridge RA
Year: 2013
Journal: PLoS Biol
Title: Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism.
Volume: 11
Issue: 9
Pages: e1001666
Publication
First Author: Lu S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture.
Volume: 478
Issue: 4
Pages: 1726-31
Publication  
First Author: Zheng M
Year: 2021
Journal: Int J Mol Sci
Title: Bmp Signaling Regulates Hand1 in a Dose-Dependent Manner during Heart Development.
Volume: 22
Issue: 18
Publication  
First Author: Funato N
Year: 2020
Journal: Int J Mol Sci
Title: The Transcription Factor HAND1 Is Involved in Cortical Bone Mass through the Regulation of Collagen Expression.
Volume: 21
Issue: 22
Publication
First Author: Hill AA
Year: 2004
Journal: Mol Cell Biol
Title: Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2.
Volume: 24
Issue: 22
Pages: 9835-47
Publication
First Author: Scott IC
Year: 2000
Journal: Mol Cell Biol
Title: The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms.
Volume: 20
Issue: 2
Pages: 530-41
Publication
First Author: Firulli BA
Year: 2017
Journal: Cardiovasc Res
Title: The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice.
Volume: 113
Issue: 14
Pages: 1732-1742
Publication
First Author: Firulli BA
Year: 2020
Journal: Cardiovasc Res
Title: HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.
Volume: 116
Issue: 3
Pages: 605-618
Publication
First Author: Barnes RM
Year: 2010
Journal: Dev Dyn
Title: Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives.
Volume: 239
Issue: 11
Pages: 3086-97
Publication
First Author: Vincentz JW
Year: 2012
Journal: J Neurosci
Title: A Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis.
Volume: 32
Issue: 6
Pages: 2110-20
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190479
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hand1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190479
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hand1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190479
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hand1
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190479
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hand1
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190479
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hand1
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190479
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hand1
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6174662
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190479
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hand1
Detected: false
Specimen Num: 7
Publication
First Author: McFadden DG
Year: 2005
Journal: Development
Title: The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner.
Volume: 132
Issue: 1
Pages: 189-201
Publication
First Author: Vincentz JW
Year: 2019
Journal: Circ Res
Title: Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function.
Volume: 125
Issue: 6
Pages: 575-589
Publication  
First Author: Courtney JA
Year: 2021
Journal: Int J Mol Sci
Title: Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy.
Volume: 22
Issue: 17
Publication
First Author: Huang F
Year: 2004
Journal: Mech Dev
Title: Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death.
Volume: 121
Issue: 6
Pages: 559-72
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Togi K
Year: 2004
Journal: Mol Cell Biol
Title: Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.
Volume: 24
Issue: 11
Pages: 4627-35
Publication
First Author: Vincentz JW
Year: 2017
Journal: PLoS Genet
Title: Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function.
Volume: 13
Issue: 7
Pages: e1006922
Publication
First Author: Firulli BA
Year: 2003
Journal: Mol Cell
Title: PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation.
Volume: 12
Issue: 5
Pages: 1225-37
Publication
First Author: Riley PR
Year: 2000
Journal: Dev Biol
Title: Early exclusion of hand1-deficient cells from distinct regions of the left ventricular myocardium in chimeric mouse embryos.
Volume: 227
Issue: 1
Pages: 156-68
Publication  
First Author: Firulli AB
Year: 2003
Journal: Gene
Title: A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors.
Volume: 312
Pages: 27-40
Publication
First Author: Firulli AB
Year: 1998
Journal: Nat Genet
Title: Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1.
Volume: 18
Issue: 3
Pages: 266-70
Publication
First Author: Lu S
Year: 2011
Journal: PLoS One
Title: Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling.
Volume: 6
Issue: 4
Pages: e19251
Publication  
First Author: Smart N
Year: 2010
Journal: Nat Commun
Title: Identification of Thymosin β4 as an effector of Hand1-mediated vascular development.
Volume: 1
Pages: 46
Publication
First Author: Vincentz JW
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap.
Volume: 113
Issue: 27
Pages: 7563-8
Publication
First Author: D'Autréaux F
Year: 2007
Journal: Development
Title: Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia.
Volume: 134
Issue: 12
Pages: 2237-49
Publication
First Author: Niu Z
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart.
Volume: 105
Issue: 46
Pages: 17824-9
Publication
First Author: Barnes RM
Year: 2011
Journal: Circ Res
Title: Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development.
Volume: 108
Issue: 8
Pages: 940-9
Publication
First Author: McFadden DG
Year: 2002
Journal: Development
Title: Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding.
Volume: 129
Issue: 13
Pages: 3077-88
Publication  
First Author: Vincentz JW
Year: 2021
Journal: Dev Biol
Title: HAND transcription factors cooperatively specify the aorta and pulmonary trunk.
Volume: 476
Pages: 1-10
Publication
First Author: Funato N
Year: 2009
Journal: Development
Title: Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2.
Volume: 136
Issue: 4
Pages: 615-25
Publication
First Author: Simmons DG
Year: 2008
Journal: Development
Title: Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth.
Volume: 135
Issue: 12
Pages: 2083-91
Publication
First Author: Christoffels VM
Year: 2000
Journal: Dev Biol
Title: Chamber formation and morphogenesis in the developing mammalian heart.
Volume: 223
Issue: 2
Pages: 266-78
Publication
First Author: Togi K
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development.
Volume: 343
Issue: 1
Pages: 144-51
Publication
First Author: Vincentz JW
Year: 2008
Journal: Dev Biol
Title: An absence of Twist1 results in aberrant cardiac neural crest morphogenesis.
Volume: 320
Issue: 1
Pages: 131-9
Publication  
First Author: Sarkar AA
Year: 2016
Journal: Placenta
Title: Abnormal labyrinthine zone in the Hectd1-null placenta.
Volume: 38
Pages: 16-23
Publication
First Author: Chen YH
Year: 2007
Journal: Dev Biol
Title: Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract.
Volume: 308
Issue: 2
Pages: 421-37
Publication
First Author: Morikawa Y
Year: 2007
Journal: Dev Biol
Title: Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system.
Volume: 307
Issue: 1
Pages: 114-26
Publication
First Author: Barbosa AC
Year: 2007
Journal: Dev Biol
Title: Hand transcription factors cooperatively regulate development of the distal midline mesenchyme.
Volume: 310
Issue: 1
Pages: 154-68
Publication  
First Author: Chen YH
Year: 2008
Journal: BMC Dev Biol
Title: Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium.
Volume: 8
Pages: 75
Publication
First Author: Lai D
Year: 2010
Journal: Circ Res
Title: Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.
Volume: 107
Issue: 6
Pages: 715-27
Publication
First Author: Cai X
Year: 2011
Journal: Dev Biol
Title: Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2.
Volume: 360
Issue: 2
Pages: 381-90
Publication
First Author: Morikawa Y
Year: 2004
Journal: Development
Title: Extra-embryonic vasculature development is regulated by the transcription factor HAND1.
Volume: 131
Issue: 9
Pages: 2195-204
Publication
First Author: Tanaka M
Year: 1999
Journal: Development
Title: The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development.
Volume: 126
Issue: 6
Pages: 1269-80
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cserjesi P
Year: 1995
Journal: Dev Biol
Title: Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development.
Volume: 170
Issue: 2
Pages: 664-78
GXD Expression      
Probe: MGI:1327297
Assay Type: RT-PCR
Annotation Date: 1999-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1327303
Age: embryonic day 8.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1327297
Assay Type: RT-PCR
Annotation Date: 1999-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1327303
Age: embryonic day 8.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1330067
Assay Type: RT-PCR
Annotation Date: 1999-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:1330193
Age: embryonic day 9.5
Image: 7
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1330067
Assay Type: RT-PCR
Annotation Date: 1999-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:1330193
Age: embryonic day 9.5
Image: 7
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1330067
Assay Type: RT-PCR
Annotation Date: 1999-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:1330193
Age: embryonic day 9.5
Image: 7
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1330067
Assay Type: RT-PCR
Annotation Date: 1999-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:1330193
Age: embryonic day 9.5
Image: 7
Specimen Label: 5
Detected: true
Specimen Num: 5