Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the hyaluronan synthase 2 (HAS2), which plays a role in hyaluronan/hyaluronic acid (HA) synthesis []. There are three different, but related hyaluronan synthases - HAS1, HAS2 and HAS3. They are multipass transmembrane enzymes, the active sites of which protrude from the inner face of the plasma membrane. HA is an unbranched disaccharide glucuronic acid/N-acetylglucosamine polymer and is one of the main components of the extracellular matrix []. High level of HA in humans is associated with cancer progression [, ]. In vertebrates, different HA polymer length can trigger different biological responses. High-molecular-mass HA represses mitogenic signalling and has anti-inflammatory properties, while low-molecular-mass HA promotes proliferation and inflammation [, ]. A study of the naked mole rat showed that HAS2 is overexpressed in naked mole rat fibroblasts, while the expression levels of HAS1 and HAS3 are similar between mouse, human and naked mole-rat cells []. HAS2 is responsible for the synthesis of the high-molecular-mass HA (HMM-HA), which triggers ECI (early contact inhibition) via the CD44 receptor and plays a key role in mediating the cancer resistance of the naked mole rat []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian X |
Year: |
2013 |
Journal: |
Nature |
Title: |
High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. |
Volume: |
499 |
Issue: |
7458 |
Pages: |
346-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toole BP |
Year: |
2004 |
Journal: |
Nat Rev Cancer |
Title: |
Hyaluronan: from extracellular glue to pericellular cue. |
Volume: |
4 |
Issue: |
7 |
Pages: |
528-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lipponen P |
Year: |
2001 |
Journal: |
Eur J Cancer |
Title: |
High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer. |
Volume: |
37 |
Issue: |
7 |
Pages: |
849-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kothapalli D |
Year: |
2007 |
Journal: |
J Cell Biol |
Title: |
Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells. |
Volume: |
176 |
Issue: |
4 |
Pages: |
535-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tseng V |
Year: |
2022 |
Journal: |
Matrix Biol |
Title: |
3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension. |
Volume: |
111 |
|
Pages: |
53-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klewer SE |
Year: |
2006 |
Journal: |
Gene Expr Patterns |
Title: |
Has2 expression in heart forming regions is independent of BMP signaling. |
Volume: |
6 |
Issue: |
5 |
Pages: |
462-70 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
552
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugiura K |
Year: |
2009 |
Journal: |
Mol Reprod Dev |
Title: |
Targeted suppression of Has2 mRNA in mouse cumulus cell-oocyte complexes by adenovirus-mediated short-hairpin RNA expression. |
Volume: |
76 |
Issue: |
6 |
Pages: |
537-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walker JKL |
Year: |
2017 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Targeted HAS2 Expression Lessens Airway Responsiveness in Chronic Murine Allergic Airway Disease. |
Volume: |
57 |
Issue: |
6 |
Pages: |
702-710 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2022 |
Journal: |
Biomolecules |
Title: |
FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway. |
Volume: |
12 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Moffatt P |
Year: |
2011 |
Journal: |
Dev Dyn |
Title: |
Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development. |
Volume: |
240 |
Issue: |
2 |
Pages: |
404-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsumoto K |
Year: |
2009 |
Journal: |
Development |
Title: |
Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. |
Volume: |
136 |
Issue: |
16 |
Pages: |
2825-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sherpa MT |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Has2 Regulates the Development of Ovalbumin-Induced Airway Remodeling and Steroid Insensitivity in Mice. |
Volume: |
12 |
|
Pages: |
770305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi N |
Year: |
2010 |
Journal: |
Cancer Res |
Title: |
Hyaluronan deficiency in tumor stroma impairs macrophage trafficking and tumor neovascularization. |
Volume: |
70 |
Issue: |
18 |
Pages: |
7073-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spicer AP |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning and characterization of a putative mouse hyaluronan synthase. |
Volume: |
271 |
Issue: |
38 |
Pages: |
23400-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2016 |
Journal: |
Matrix Biol |
Title: |
Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. |
Volume: |
55 |
|
Pages: |
35-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
van den Berg BM |
Year: |
2019 |
Journal: |
J Am Soc Nephrol |
Title: |
Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium. |
Volume: |
30 |
Issue: |
10 |
Pages: |
1886-1897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SM |
Year: |
2022 |
Journal: |
Exp Mol Med |
Title: |
Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4. |
Volume: |
54 |
Issue: |
6 |
Pages: |
739-752 |
|
•
•
•
•
•
|
Publication |
First Author: |
Röck K |
Year: |
2015 |
Journal: |
J Invest Dermatol |
Title: |
miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging. |
Volume: |
135 |
Issue: |
2 |
Pages: |
369-377 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stock AE |
Year: |
2002 |
Journal: |
Endocrinology |
Title: |
Induction of hyaluronan synthase 2 by human chorionic gonadotropin in mural granulosa cells of equine preovulatory follicles. |
Volume: |
143 |
Issue: |
11 |
Pages: |
4375-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeo S |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila. |
Volume: |
279 |
Issue: |
18 |
Pages: |
18920-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Camenisch TD |
Year: |
2000 |
Journal: |
J Clin Invest |
Title: |
Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. |
Volume: |
106 |
Issue: |
3 |
Pages: |
349-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang YM |
Year: |
2019 |
Journal: |
Sci Transl Med |
Title: |
Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. |
Volume: |
11 |
Issue: |
496 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Itano N |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. |
Volume: |
274 |
Issue: |
35 |
Pages: |
25085-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44. |
Volume: |
208 |
Issue: |
7 |
Pages: |
1459-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goncharova V |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis. |
Volume: |
287 |
Issue: |
30 |
Pages: |
25419-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin X |
Year: |
2022 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Hyaluronan Modulates the Biomechanical Properties of the Cornea. |
Volume: |
63 |
Issue: |
13 |
Pages: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Törrönen K |
Year: |
2014 |
Journal: |
Histochem Cell Biol |
Title: |
Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes. |
Volume: |
141 |
Issue: |
1 |
Pages: |
17-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spicer AP |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family. |
Volume: |
273 |
Issue: |
4 |
Pages: |
1923-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morita T |
Year: |
2016 |
Journal: |
Gene Expr Patterns |
Title: |
An in situ hybridization study of Hyaluronan synthase (Has) mRNA in developing mouse molar and incisor tooth germs. |
Volume: |
21 |
Issue: |
1 |
Pages: |
28-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shirai M |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. |
Volume: |
106 |
Issue: |
44 |
Pages: |
18604-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sapudom J |
Year: |
2020 |
Journal: |
Biomater Sci |
Title: |
Biomimetic tissue models reveal the role of hyaluronan in melanoma proliferation and invasion. |
Volume: |
8 |
Issue: |
5 |
Pages: |
1405-1417 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim M |
Year: |
2022 |
Journal: |
Biol Open |
Title: |
Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. |
Volume: |
11 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sugiyama Y |
Year: |
1998 |
Journal: |
J Invest Dermatol |
Title: |
Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells. |
Volume: |
110 |
Issue: |
2 |
Pages: |
116-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Usui T |
Year: |
2000 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Expression regulation of hyaluronan synthase in corneal endothelial cells. |
Volume: |
41 |
Issue: |
11 |
Pages: |
3261-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yonemitsu MA |
Year: |
2020 |
Journal: |
Dev Biol |
Title: |
Hyaluronic acid is required for palatal shelf movement and its interaction with the tongue during palatal shelf elevation. |
Volume: |
457 |
Issue: |
1 |
Pages: |
57-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tammi R |
Year: |
2005 |
Journal: |
J Invest Dermatol |
Title: |
Hyaluronan synthase induction and hyaluronan accumulation in mouse epidermis following skin injury. |
Volume: |
124 |
Issue: |
5 |
Pages: |
898-905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takechi M |
Year: |
2020 |
Journal: |
Biochim Biophys Acta Gen Subj |
Title: |
A pericellular hyaluronan matrix is required for the morphological maturation of cortical neurons. |
Volume: |
1864 |
Issue: |
10 |
Pages: |
129679 |
|
•
•
•
•
•
|
Publication |
First Author: |
Galloway JL |
Year: |
2013 |
Journal: |
Front Physiol |
Title: |
The control and importance of hyaluronan synthase expression in palatogenesis. |
Volume: |
4 |
|
Pages: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spicer AP |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Chromosomal localization of the human and mouse hyaluronan synthase genes. |
Volume: |
41 |
Issue: |
3 |
Pages: |
493-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kakoi H |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism. |
Volume: |
289 |
Issue: |
12 |
Pages: |
8135-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu J |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning. |
Volume: |
375 |
Issue: |
2 |
Pages: |
160-71 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Semino CE |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embryogenesis. |
Volume: |
93 |
Issue: |
10 |
Pages: |
4548-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Puri S |
Year: |
2020 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Epithelial Cell Migration and Proliferation Patterns During Initial Wound Closure in Normal Mice and an Experimental Model of Limbal Stem Cell Deficiency. |
Volume: |
61 |
Issue: |
10 |
Pages: |
27 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654814 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-16 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:2654827 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
E10.5 1/3 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654814 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-16 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:2654827 |
Age: |
embryonic day 14.5 |
Image: |
1 |
|
Specimen Label: |
E14.5 1/3 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654815 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-16 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:2654828 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
E10.5 1/5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654815 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-16 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:2654828 |
Age: |
embryonic day 14.5 |
Image: |
1 |
|
Specimen Label: |
E14.5 1/5 |
|
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Heart |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Spleen |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Lung |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Liver |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Skeletal muscle |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2654830 |
Age: |
postnatal adult |
Image: |
5 |
|
Specimen Label: |
Kidney |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:2654833 |
Age: |
embryonic day 7.5 |
Image: |
5 |
|
Specimen Label: |
7.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603919 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2654833 |
Age: |
embryonic day 11.5 |
Image: |
5 |
|
Specimen Label: |
11.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
|
Stage: |
TS23 |
Assay Id: |
MGI:2654833 |
Age: |
embryonic day 15.5 |
Image: |
5 |
|
Specimen Label: |
15.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2654812 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
|
Stage: |
TS25 |
Assay Id: |
MGI:2654833 |
Age: |
embryonic day 17.5 |
Image: |
5 |
|
Specimen Label: |
17.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3720575 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-09-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736221 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3720753 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3720575 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-09-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736221 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3720753 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3720575 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-09-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736221 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3720753 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5804773 |
Assay Type: |
RT-PCR |
Annotation Date: |
2016-10-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3289722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5804779 |
Age: |
embryonic day 14.0 |
Image: |
1 |
|
Specimen Label: |
E14.0 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5804773 |
Assay Type: |
RT-PCR |
Annotation Date: |
2016-10-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3289724 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5804779 |
Age: |
embryonic day 16.0 |
Image: |
1 |
|
Specimen Label: |
E16.0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5804773 |
Assay Type: |
RT-PCR |
Annotation Date: |
2016-10-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3289726 |
|
Stage: |
TS26 |
Assay Id: |
MGI:5804779 |
Age: |
embryonic day 18.0 |
Image: |
1 |
|
Specimen Label: |
E18.0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6726339 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-07-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6726429 |
Age: |
embryonic day 13.5 |
Image: |
9 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6726339 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-07-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6726429 |
Age: |
embryonic day 13.5 |
Image: |
9 |
|
Specimen Label: |
cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466095 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610520 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7466096 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466095 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610520 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7466096 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|