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Search results 1 to 100 out of 319 for Hbp1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: HMG box-containing protein 1 (HBP1) is a high mobility group (HMG) box transcription factor that negatively regulates the Wnt-beta-catenin pathway []and is involved in histone H1(0) gene expression []. It binds the transcription factor TCF4 and prevents it from binding to its target genes, including c-MYC and CYCLIN D []. It acts as a tumour suppressor and an important effector in oncogene-induced premature senescence [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Spiller CM
Year: 2017
Journal: PLoS One
Title: Mice Lacking Hbp1 Function Are Viable and Fertile.
Volume: 12
Issue: 1
Pages: e0170576
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464913
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464916
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
Publication
First Author: Swanson KA
Year: 2004
Journal: Nat Struct Mol Biol
Title: HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.
Volume: 11
Issue: 8
Pages: 738-46
Publication
First Author: Lemercier C
Year: 2000
Journal: Mol Cell Biol
Title: Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression.
Volume: 20
Issue: 18
Pages: 6627-37
Publication
First Author: Escamilla-Powers JR
Year: 2010
Journal: J Biol Chem
Title: The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.
Volume: 285
Issue: 7
Pages: 4847-58
Publication
First Author: Lavender P
Year: 1997
Journal: Oncogene
Title: The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A.
Volume: 14
Issue: 22
Pages: 2721-8
Publication
First Author: Borrelli S
Year: 2010
Journal: Cell Death Differ
Title: The p63 target HBP1 is required for skin differentiation and stratification.
Volume: 17
Issue: 12
Pages: 1896-907
Publication
First Author: Tian FJ
Year: 2014
Journal: Cardiovasc Res
Title: Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis.
Volume: 103
Issue: 1
Pages: 100-10
Publication
First Author: Shih HH
Year: 2001
Journal: Mol Cell Biol
Title: HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue.
Volume: 21
Issue: 17
Pages: 5723-32
Publication
First Author: Coomans de Brachène A
Year: 2014
Journal: Biochem J
Title: The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway.
Volume: 460
Issue: 1
Pages: 25-34
Publication
First Author: Watanabe N
Year: 2015
Journal: Development
Title: Hbp1 regulates the timing of neuronal differentiation during cortical development by controlling cell cycle progression.
Volume: 142
Issue: 13
Pages: 2278-90
Publication
First Author: Dong Z
Year: 2016
Journal: Cell Death Differ
Title: Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve.
Volume: 23
Issue: 10
Pages: 1602-14
Publication
First Author: Smith JM
Year: 2004
Journal: Dev Dyn
Title: HMG box transcription factor gene Hbp1 is expressed in germ cells of the developing mouse testis.
Volume: 230
Issue: 2
Pages: 366-70
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190483
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hbp1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190483
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hbp1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190483
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hbp1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190483
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hbp1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190483
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hbp1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190483
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hbp1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6174704
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190483
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hbp1
Detected: true
Specimen Num: 7
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
Publication
First Author: Sampson EM
Year: 2001
Journal: EMBO J
Title: Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1.
Volume: 20
Issue: 16
Pages: 4500-11
Publication
First Author: de Chiara C
Year: 2003
Journal: FEBS Lett
Title: The AXH module: an independently folded domain common to ataxin-1 and HBP1.
Volume: 551
Issue: 1-3
Pages: 107-12
Publication
First Author: Zhuma T
Year: 1999
Journal: EMBO J
Title: Human HMG box transcription factor HBP1: a role in hCD2 LCR function.
Volume: 18
Issue: 22
Pages: 6396-406
Publication
First Author: Tevosian SG
Year: 1997
Journal: Genes Dev
Title: HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family.
Volume: 11
Issue: 3
Pages: 383-96
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3047287
Assay Type: RT-PCR
Annotation Date: 2004-08-12
Strength: Present
Sex: Male
Emaps: EMAPS:1796821
Stage: TS21
Assay Id: MGI:3047310
Age: embryonic day 13.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3047287
Assay Type: RT-PCR
Annotation Date: 2004-08-12
Strength: Present
Sex: Male
Emaps: EMAPS:1796821
Stage: TS21
Assay Id: MGI:3047310
Age: embryonic day 13.5
Image: 2
Specimen Label: W/W
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3047287
Assay Type: RT-PCR
Annotation Date: 2004-08-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:3047395
Age: postnatal newborn
Specimen Label: newborn
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3047287
Assay Type: RT-PCR
Annotation Date: 2004-08-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3047395
Age: postnatal week 1
Specimen Label: week-old
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3784537
Assay Type: RT-PCR
Annotation Date: 2008-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654814
Stage: TS14
Assay Id: MGI:3784536
Age: embryonic day 9.0
Specimen Label: 16-20s
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3784537
Assay Type: RT-PCR
Annotation Date: 2008-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654815
Stage: TS15
Assay Id: MGI:3784536
Age: embryonic day 9.5
Specimen Label: 26-30s
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816584
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816584
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816584
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816584
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816584
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816584
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816584
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815780
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816584
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464893
Age: embryonic day 13.5
Image: 2
Specimen Label: Wildtype XY
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:7464893
Age: embryonic day 13.5
Image: 2
Specimen Label: Wildtype XX
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464893
Age: embryonic day 13.5
Image: 2
Specimen Label: W/W XY
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:7464893
Age: embryonic day 13.5
Image: 2
Specimen Label: W/W XX
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464894
Age: embryonic day 13.5
Image: 2
Specimen Label: Wildtype XY
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:7464894
Age: embryonic day 13.5
Image: 2
Specimen Label: Wildtype XX
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464894
Age: embryonic day 13.5
Image: 2
Specimen Label: W/W XY
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:7464894
Age: embryonic day 13.5
Image: 2
Specimen Label: W/W XX
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464895
Age: embryonic day 13.5
Image: 2
Specimen Label: E13.5 XY
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:7464895
Age: embryonic day 13.5
Image: 2
Specimen Label: E13.5 XX
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:7464895
Age: embryonic day 12.5
Image: 2
Specimen Label: E12.5 XY
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:7464895
Age: embryonic day 12.5
Image: 2
Specimen Label: E12.5 XX
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:7464895
Age: embryonic day 14.5
Image: 2
Specimen Label: E14.5 XY
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:7464895
Age: embryonic day 14.5
Image: 2
Specimen Label: E14.5 XX
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:7464895
Age: embryonic day 15.5
Image: 2
Specimen Label: E15.5 XY
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:7464895
Age: embryonic day 15.5
Image: 2
Specimen Label: E15.5 XX
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464895
Age: embryonic day 16.5
Image: 2
Specimen Label: E16.5 XY
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7464866
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:7464895
Age: embryonic day 16.5
Image: 2
Specimen Label: E16.5 XX
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:7464896
Age: embryonic day 12.5
Image: 2
Specimen Label: E12.5 XY
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:7464896
Age: embryonic day 12.5
Image: 2
Specimen Label: E12.5 XX
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7464867
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:7464896
Age: embryonic day 13.5
Image: 2
Specimen Label: E13.5 XY
Detected: true
Specimen Num: 3