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Search results 1 to 100 out of 260 for Hcn2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
100487897 | hcn2
Type: gene
Organism: frog, western clawed
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Gene
610 | HCN2
Type: gene
Organism: human
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Gene
114244 | Hcn2
Type: gene
Organism: rat
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Gene
448791 | HCN2
Type: gene
Organism: dog, domestic
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Gene
749873 | HCN2
Type: gene
Organism: chimpanzee
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Gene
100297361 | HCN2
Type: gene
Organism: cattle
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Gene
770384 | HCN2
Type: gene
Organism: chicken
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Gene
100425114 | HCN2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1298210 | Hcn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24085296 | J:207243
First Author: Carlson AE
Year: 2013
Journal: J Biol Chem
Title: Flavonoid regulation of HCN2 channels.
Volume: 288
Issue: 46
Pages: 33136-45
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GXD Expression
GXD Expression
   
Probe: MGI:4425298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4825335
Age: embryonic day 14.5
Specimen Label: Table S5 - Hcn2
Detected: true
Specimen Num: 1
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Publication
34341156 | J:310656
First Author: Swire M
Year: 2021
Journal: J Neurosci
Title: Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length.
Volume: 41
Issue: 38
Pages: 7954-7964
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Publication
31045576 | J:298057
 
First Author: Hammelmann V
Year: 2019
Journal: JCI Insight
Title: Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures.
Volume: 4
Issue: 9
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Publication
31087220 | J:289195
First Author: Oshita K
Year: 2019
Journal: J Physiol Sci
Title: Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia.
Volume: 69
Issue: 4
Pages: 653-660
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Publication
21903816 | J:176663
First Author: Emery EC
Year: 2011
Journal: Science
Title: HCN2 ion channels play a central role in inflammatory and neuropathic pain.
Volume: 333
Issue: 6048
Pages: 1462-6
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Publication
29256865 | J:256759
   
First Author: Zhong P
Year: 2018
Journal: Elife
Title: HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress.
Volume: 7
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Publication
16542642 | J:108105
First Author: Shin M
Year: 2006
Journal: Brain Res
Title: Evaluation of HCN2 abnormalities as a cause of juvenile audiogenic seizures in Black Swiss mice.
Volume: 1083
Issue: 1
Pages: 14-20
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Publication
29466436 | J:257405
First Author: Fisher DW
Year: 2018
Journal: PLoS One
Title: Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice.
Volume: 13
Issue: 2
Pages: e0193012
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Publication
28767511 | J:351946
First Author: Herrmann S
Year: 2017
Journal: Pain
Title: Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons.
Volume: 158
Issue: 10
Pages: 2012-2024
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Publication
19574228 | J:155514
First Author: Ye B
Year: 2009
Journal: J Biol Chem
Title: Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.
Volume: 284
Issue: 38
Pages: 25553-9
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Protein
C9K0Z8
Organism: Mus musculus/domesticus
Length: 863  
Fragment?: false
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Publication
26559974 | J:228572
First Author: DeBerg HA
Year: 2016
Journal: J Biol Chem
Title: Structure and Energetics of Allosteric Regulation of HCN2 Ion Channels by Cyclic Nucleotides.
Volume: 291
Issue: 1
Pages: 371-81
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Publication
22948144 | J:192134
First Author: Ramakrishnan NA
Year: 2012
Journal: J Biol Chem
Title: HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.
Volume: 287
Issue: 45
Pages: 37628-46
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GXD Expression
GXD Expression
Probe: MGI:7716809
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7716872
Age: postnatal day 0
Image: 2E-1
Note: Expression in cells migrating from ventricular zone, more prominent for Hcn1 and Hcn2 than for Hcn4.
Specimen Label: 2E-1
Detected: true
Specimen Num: 2
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Publication
- | J:187506
     
First Author: Karst SY
Year: 2012
Journal: MGI Direct Data Submission
Title: Tremor and reduced lifespan (trls): a spontaneous missense mutation in Hcn2
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Publication
12514127 | J:81398
First Author: Ludwig A
Year: 2003
Journal: EMBO J
Title: Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.
Volume: 22
Issue: 2
Pages: 216-24
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Publication
- | J:267669
     
First Author: Mukherjee S
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for curveball2.
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Publication
- | J:272834
     
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for asombrarse.
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Publication
22279546 | J:184238
First Author: Della Santina L
Year: 2012
Journal: PLoS One
Title: Processing of retinal signals in normal and HCN deficient mice.
Volume: 7
Issue: 1
Pages: e29812
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Publication
24638995 | J:303019
First Author: Horwitz GC
Year: 2014
Journal: J Gen Physiol
Title: Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons.
Volume: 143
Issue: 4
Pages: 481-97
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Publication
19150498 | J:146530
First Author: Chung WK
Year: 2009
Journal: Neurobiol Dis
Title: Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2.
Volume: 33
Issue: 3
Pages: 499-508
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Publication
31496517 | J:279117
   
First Author: Byczkowicz N
Year: 2019
Journal: Elife
Title: HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons.
Volume: 8
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Publication
25800552 | J:245301
First Author: DeBerg HA
Year: 2015
Journal: Structure
Title: Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b.
Volume: 23
Issue: 4
Pages: 734-44
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Publication
12968185 | J:314074
First Author: Zagotta WN
Year: 2003
Journal: Nature
Title: Structural basis for modulation and agonist specificity of HCN pacemaker channels.
Volume: 425
Issue: 6954
Pages: 200-5
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Publication
14726518 | J:89171
First Author: Decher N
Year: 2004
Journal: J Biol Chem
Title: Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.
Volume: 279
Issue: 14
Pages: 13859-65
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Publication
25423599 | J:218796
First Author: Li M
Year: 2015
Journal: Biochem J
Title: Effects of N-glycosylation on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Volume: 466
Issue: 1
Pages: 77-84
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Publication
25562801 | J:225766
 
First Author: Oshita K
Year: 2015
Journal: J Mol Cell Cardiol
Title: Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2.
Volume: 80
Pages: 81-9
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Publication
16923750 | J:125246
First Author: Bucchi A
Year: 2006
Journal: Circulation
Title: Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker.
Volume: 114
Issue: 10
Pages: 992-9
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Publication
21076425 | J:170270
First Author: Chan CS
Year: 2011
Journal: Nat Neurosci
Title: HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.
Volume: 14
Issue: 1
Pages: 85-92
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Publication
30877792 | J:274719
     
First Author: Zobeiri M
Year: 2019
Journal: Cereb Cortex
Title: The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.
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Publication
18033814 | J:176409
First Author: Qu Y
Year: 2008
Journal: J Physiol
Title: Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.
Volume: 586
Issue: 3
Pages: 701-16
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Publication
22550182 | J:184786
First Author: Bankston JR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Volume: 109
Issue: 20
Pages: 7899-904
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Publication
38124021 | J:354124
 
First Author: Han X
Year: 2024
Journal: J Neurosci
Title: Opioid-Induced Hyperalgesia and Tolerance Are Driven by HCN Ion Channels.
Volume: 44
Issue: 6
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Publication
19524546 | J:153459
First Author: Rozario AO
Year: 2009
Journal: Biochim Biophys Acta
Title: Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring.
Volume: 1788
Issue: 9
Pages: 1939-49
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Publication
19570998 | J:301120
First Author: Alig J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Control of heart rate by cAMP sensitivity of HCN channels.
Volume: 106
Issue: 29
Pages: 12189-94
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Publication
31290157 | J:302875
First Author: Lainez S
Year: 2019
Journal: J Physiol
Title: HCN3 ion channels: roles in sensory neuronal excitability and pain.
Volume: 597
Issue: 17
Pages: 4661-4675
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Publication
22090507 | J:177907
First Author: Horwitz GC
Year: 2011
Journal: J Neurosci
Title: HCN channels expressed in the inner ear are necessary for normal balance function.
Volume: 31
Issue: 46
Pages: 16814-25
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Publication
16079136 | J:200307
First Author: Zong X
Year: 2005
Journal: J Biol Chem
Title: A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.
Volume: 280
Issue: 40
Pages: 34224-32
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Publication
16806719 | J:113160
First Author: Abbas SY
Year: 2006
Journal: Neuroscience
Title: Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.
Volume: 141
Issue: 4
Pages: 1811-25
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Publication
15292205 | J:93990
First Author: Gravante B
Year: 2004
Journal: J Biol Chem
Title: Interaction of the pacemaker channel HCN1 with filamin A.
Volume: 279
Issue: 42
Pages: 43847-53
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Publication
22652004 | J:330478
First Author: Hofmann F
Year: 2012
Journal: Cardiovasc Res
Title: Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.
Volume: 95
Issue: 3
Pages: 317-26
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Publication
22880098 | J:189820
First Author: Ying SW
Year: 2012
Journal: PLoS One
Title: Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.
Volume: 7
Issue: 8
Pages: e42756
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Protein Coding Gene
MGP_CAROLIEiJ_G0015537 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017433 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1298210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017316 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016566 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016845 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030950 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016355 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:103185
     
First Author: Samples R
Year: 2005
Journal: MGI Direct Data Submission
Title: Tremor and reduced lifespan (trls): a new neurological mutation on Chromosome 10
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Publication
- | J:140623
     
First Author: Karst SY
Year: 2008
Journal: MGI Direct Data Submission
Title: Tremor and reduced lifespan 2 Jackson: a new remutation on Chromosome 10
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Publication
- | J:255187
     
First Author: Russell J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for curveball
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Publication
- | J:274859
     
First Author: Zhao Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for mire.
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Publication
34818058 | J:325470
First Author: Lyman KA
Year: 2021
Journal: Sci Transl Med
Title: Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior.
Volume: 13
Issue: 621
Pages: eabl4580
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Publication
24958877 | J:212171
First Author: Puljung MC
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Double electron-electron resonance reveals cAMP-induced conformational change in HCN channels.
Volume: 111
Issue: 27
Pages: 9816-21
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610523
Stage: TS23
Assay Id: MGI:3054214
Age: embryonic day 15.5
Image: 2
Specimen Label: E15.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610523
Stage: TS23
Assay Id: MGI:3054214
Age: embryonic day 15.5
Image: 2
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3054214
Age: postnatal day 18
Image: 2
Specimen Label: P18
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3054214
Age: postnatal day 18
Image: 2
Specimen Label: P18
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3054214
Age: postnatal adult
Image: 2
Specimen Label: A11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3054213
Assay Type: RT-PCR
Annotation Date: 2004-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3054214
Age: postnatal adult
Image: 2
Specimen Label: A11
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3608933
Assay Type: RT-PCR
Annotation Date: 2006-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3608936
Age: postnatal week 8
Specimen Label: NTg
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3608939
Assay Type: Western blot
Annotation Date: 2006-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3608945
Age: postnatal week 8
Specimen Label: NTg
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3608939
Assay Type: Western blot
Annotation Date: 2006-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3608945
Age: postnatal week 8
Specimen Label: NTg
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733125
Stage: TS25
Assay Id: MGI:3708504
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733127
Stage: TS27
Assay Id: MGI:3708504
Age: postnatal day 1
Specimen Label: Neonate
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Male
Emaps: EMAPS:1733128
Stage: TS28
Assay Id: MGI:3708504
Age: postnatal week 5-8
Specimen Label: Adult
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3709285
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3709285
Age: postnatal day 1
Specimen Label: Neonate
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3707878
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3709285
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Stage: TS21
Assay Id: MGI:7281448
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691023
Stage: TS23
Assay Id: MGI:7281448
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691026
Stage: TS26
Assay Id: MGI:7281448
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7281448
Age: postnatal day 7
Image: 1
Specimen Label: P7
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7281448
Age: postnatal day 35
Image: 1
Specimen Label: P35
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:7281457
Age: embryonic day 13.0
Image: S1
Specimen Label: E13
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7281457
Age: embryonic day 15.0
Image: S1
Specimen Label: E15
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7281404
Assay Type: RT-PCR
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7281457
Age: embryonic day 18.0
Image: S1
Specimen Label: E18
Detected: true
Specimen Num: 3
•
•
•
•
•




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