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Search results 1 to 100 out of 416 for Hcrt

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
3060 | HCRT
Type: gene
Organism: human
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Gene
281222 | HCRT
Type: gene
Organism: cattle
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Gene
374005 | HCRT
Type: gene
Organism: chicken
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Gene
613239 | hcrt
Type: gene
Organism: zebrafish
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Gene
709564 | HCRT
Type: gene
Organism: macaque, rhesus
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Gene
101731540 | hcrt
Type: gene
Organism: frog, western clawed
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Gene
key_65124 | HCRT
Type: gene
Organism: pig, domestic
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Gene
25723 | Hcrt
Type: gene
Organism: rat
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Gene
607641 | HCRT
Type: gene
Organism: dog, domestic
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Gene
742546 | HCRT
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1202306 | Hcrt
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3618774
Assay Type: RNA in situ
Annotation Date: 2006-04-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3618779
Age: embryonic day 18.5
Note: Expression is in the lateral anterior hypothalamus.
Specimen Label: Hcrt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190485
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hcrt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190485
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hcrt
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190485
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hcrt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190485
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hcrt
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190485
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hcrt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190485
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hcrt
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6174723
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190485
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hcrt
Detected: true
Specimen Num: 7
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Publication
23516292 | J:196592
First Author: Yang L
Year: 2013
Journal: J Neurosci
Title: Hypocretin/orexin neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice.
Volume: 33
Issue: 12
Pages: 5275-84
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Publication
22357806 | J:226143
First Author: Silvani A
Year: 2012
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Control of cardiovascular variability during undisturbed wake-sleep behavior in hypocretin-deficient mice.
Volume: 302
Issue: 8
Pages: R958-64
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Publication
18551194 | J:137688
First Author: Xie X
Year: 2008
Journal: J Clin Invest
Title: Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia.
Volume: 118
Issue: 7
Pages: 2471-81
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Publication
35201886 | J:323820
First Author: Li SB
Year: 2022
Journal: Science
Title: Hyperexcitable arousal circuits drive sleep instability during aging.
Volume: 375
Issue: 6583
Pages: eabh3021
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Publication
28608460 | J:256361
First Author: Ogawa Y
Year: 2017
Journal: J Comp Neurol
Title: Anatomical and electrophysiological development of the hypothalamic orexin neurons from embryos to neonates.
Volume: 525
Issue: 18
Pages: 3809-3820
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Publication
30726119 | J:274908
First Author: Stanojlovic M
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Chemogenetic activation of orexin/hypocretin neurons ameliorates aging-induced changes in behavior and energy expenditure.
Volume: 316
Issue: 5
Pages: R571-R583
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Publication
33466831 | J:342005
 
First Author: Stanojlovic M
Year: 2021
Journal: Int J Mol Sci
Title: Inhibition of Orexin/Hypocretin Neurons Ameliorates Elevated Physical Activity and Energy Expenditure in the A53T Mouse Model of Parkinson's Disease.
Volume: 22
Issue: 2
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Publication
11394998 | J:69620
First Author: Hara J
Year: 2001
Journal: Neuron
Title: Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.
Volume: 30
Issue: 2
Pages: 345-54
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Publication
16410401 | J:201120
First Author: Zhang W
Year: 2006
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice.
Volume: 290
Issue: 6
Pages: R1654-63
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Publication
23700511 | J:262345
First Author: Sellayah D
Year: 2012
Journal: Adipocyte
Title: Orexin receptor-1 mediates brown fat developmental differentiation.
Volume: 1
Issue: 1
Pages: 58-63
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Publication
15579160 | J:101276
First Author: Akiyama M
Year: 2004
Journal: Eur J Neurosci
Title: Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice.
Volume: 20
Issue: 11
Pages: 3054-62
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Publication
15862893 | J:104865
First Author: Hara J
Year: 2005
Journal: Neurosci Lett
Title: Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions.
Volume: 380
Issue: 3
Pages: 239-42
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Publication
19750917 | J:324849
First Author: Kantor S
Year: 2009
Journal: Sleep
Title: Orexin neurons are necessary for the circadian control of REM sleep.
Volume: 32
Issue: 9
Pages: 1127-34
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Publication
19703479 | J:179565
First Author: Mori T
Year: 2010
Journal: Neuropharmacology
Title: Monoaminergic neuronal changes in orexin deficient mice.
Volume: 58
Issue: 4-5
Pages: 826-32
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Publication
24772478 | J:312042
First Author: Bastianini S
Year: 2014
Journal: J Sleep Res
Title: A critical role of hypocretin deficiency in pregnancy.
Volume: 23
Issue: 2
Pages: 186-8
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Publication
20807795 | J:179546
First Author: Zhang W
Year: 2010
Journal: J Physiol
Title: Orexin neurons are indispensable for stress-induced thermogenesis in mice.
Volume: 588
Issue: Pt 21
Pages: 4117-29
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Publication
16626839 | J:128233
First Author: Fujiki N
Year: 2006
Journal: Peptides
Title: Sex difference in body weight gain and leptin signaling in hypocretin/orexin deficient mouse models.
Volume: 27
Issue: 9
Pages: 2326-31
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Publication
31375626 | J:279058
First Author: Seifinejad A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons.
Volume: 116
Issue: 34
Pages: 17061-17070
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Publication
36275002 | J:331068
 
First Author: Nick H
Year: 2022
Journal: Front Aging Neurosci
Title: Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus.
Volume: 14
Pages: 1025402
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Publication
29454841 | J:273676
 
First Author: Steiner N
Year: 2018
Journal: Neuropharmacology
Title: Hypocretin/orexin deficiency decreases cocaine abuse liability.
Volume: 133
Pages: 395-403
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Publication
22031892 | J:177267
First Author: McGregor R
Year: 2011
Journal: J Neurosci
Title: Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level.
Volume: 31
Issue: 43
Pages: 15455-67
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Publication
27480648 | J:270361
First Author: Shaw JK
Year: 2017
Journal: Addict Biol
Title: Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine.
Volume: 22
Issue: 6
Pages: 1695-1705
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Publication
25066943 | J:217103
First Author: Ramanathan L
Year: 2014
Journal: J Neurochem
Title: Gender differences between hypocretin/orexin knockout and wild type mice: age, body weight, body composition, metabolic markers, leptin and insulin resistance.
Volume: 131
Issue: 5
Pages: 615-24
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Publication
11282968 | J:68677
First Author: Hungs M
Year: 2001
Journal: Genome Res
Title: Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines.
Volume: 11
Issue: 4
Pages: 531-9
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Publication
32516139 | J:300150
First Author: Tan Y
Year: 2020
Journal: J Clin Invest
Title: Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice.
Volume: 130
Issue: 9
Pages: 4985-4998
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Publication
9419374 | J:45976
First Author: de Lecea L
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
Volume: 95
Issue: 1
Pages: 322-7
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Publication
23620827 | J:200101
First Author: Furutani N
Year: 2013
Journal: PLoS One
Title: Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states.
Volume: 8
Issue: 4
Pages: e62391
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Publication
19623260 | J:151539
First Author: Kaur S
Year: 2009
Journal: PLoS One
Title: Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice.
Volume: 4
Issue: 7
Pages: e6346
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Publication
28630298 | J:244284
First Author: Vassalli A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need.
Volume: 114
Issue: 27
Pages: E5464-E5473
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Publication
28507129 | J:242285
First Author: Irukayama-Tomobe Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.
Volume: 114
Issue: 22
Pages: 5731-5736
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Publication
26474479 | J:244790
First Author: Bastianini S
Year: 2015
Journal: PLoS One
Title: Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin Neuron Deficiency.
Volume: 10
Issue: 10
Pages: e0140520
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Publication
19158946 | J:144841
First Author: Honda M
Year: 2009
Journal: PLoS One
Title: IGFBP3 colocalizes with and regulates hypocretin (orexin).
Volume: 4
Issue: 1
Pages: e4254
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Publication
19246384 | J:146778
First Author: Matsuki T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture.
Volume: 106
Issue: 11
Pages: 4459-64
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Publication
24382351 | J:208001
First Author: Hasegawa E
Year: 2014
Journal: J Clin Invest
Title: Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
Volume: 124
Issue: 2
Pages: 604-16
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Publication
32553161 | J:301227
First Author: Li P
Year: 2020
Journal: Cell Rep
Title: Brain Circuit of Claustrophobia-like Behavior in Mice Identified by Upstream Tracing of Sighing.
Volume: 31
Issue: 11
Pages: 107779
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Publication
25695914 | J:221792
 
First Author: Bonnavion P
Year: 2015
Journal: Nat Commun
Title: Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses.
Volume: 6
Pages: 6266
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Publication
16923149 | J:123643
First Author: Hunsley MS
Year: 2006
Journal: Genes Brain Behav
Title: Behavioral and sleep/wake characteristics of mice lacking norepinephrine and hypocretin.
Volume: 5
Issue: 6
Pages: 451-7
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Publication
22955882 | J:190145
First Author: Carter ME
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mechanism for Hypocretin-mediated sleep-to-wake transitions.
Volume: 109
Issue: 39
Pages: E2635-44
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Publication
29462275 | J:272252
First Author: Williams RH
Year: 2019
Journal: Cereb Cortex
Title: Excitation of Cortical nNOS/NK1R Neurons by Hypocretin 1 is Independent of Sleep Homeostasis.
Volume: 29
Issue: 3
Pages: 1090-1108
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Publication
28396432 | J:242128
First Author: Hasegawa E
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity.
Volume: 114
Issue: 17
Pages: E3526-E3535
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Protein Coding Gene
MGP_CAROLIEiJ_G0017186 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1202306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019560 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019001 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018316 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018029 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10481909 | J:57124
First Author: Chemelli RM
Year: 1999
Journal: Cell
Title: Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
Volume: 98
Issue: 4
Pages: 437-51
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Publication
23707248 | J:198995
 
First Author: Tsunematsu T
Year: 2013
Journal: Behav Brain Res
Title: Long-lasting silencing of orexin/hypocretin neurons using archaerhodopsin induces slow-wave sleep in mice.
Volume: 255
Pages: 64-74
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Publication
15525658 | J:136441
First Author: Petersén A
Year: 2005
Journal: Hum Mol Genet
Title: Orexin loss in Huntington's disease.
Volume: 14
Issue: 1
Pages: 39-47
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Publication
32694504 | J:292000
First Author: Feng H
Year: 2020
Journal: Nat Commun
Title: Orexin signaling modulates synchronized excitation in the sublaterodorsal tegmental nucleus to stabilize REM sleep.
Volume: 11
Issue: 1
Pages: 3661
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Publication
12646175 | J:201037
First Author: Yamanaka A
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Regulation of orexin neurons by the monoaminergic and cholinergic systems.
Volume: 303
Issue: 1
Pages: 120-9
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Publication
34193206 | J:346869
First Author: Yamashita A
Year: 2021
Journal: Mol Brain
Title: Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice.
Volume: 14
Issue: 1
Pages: 104
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Publication
29325715 | J:259275
 
First Author: Dang R
Year: 2018
Journal: Neurosci Lett
Title: Orexin knockout mice exhibit impaired spatial working memory.
Volume: 668
Pages: 92-97
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Publication
32303567 | J:289474
 
First Author: Sun Y
Year: 2020
Journal: eNeuro
Title: Hypothalamic MCH Neuron Activity Dynamics during Cataplexy of Narcolepsy.
Volume: 7
Issue: 2
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Publication
12716916 | J:83334
First Author: Georgescu D
Year: 2003
Journal: J Neurosci
Title: Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal.
Volume: 23
Issue: 8
Pages: 3106-11
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Publication
23739971 | J:198644
First Author: Oishi Y
Year: 2013
Journal: J Neurosci
Title: Role of the medial prefrontal cortex in cataplexy.
Volume: 33
Issue: 23
Pages: 9743-51
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Publication
37044089 | J:335759
First Author: Pintwala SK
Year: 2023
Journal: Curr Biol
Title: Immortal orexin cell transplants restore motor-arousal synchrony during cataplexy.
Volume: 33
Issue: 8
Pages: 1550-1564.e5
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Publication
12750151 | J:85405
First Author: Kayaba Y
Year: 2003
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Attenuated defense response and low basal blood pressure in orexin knockout mice.
Volume: 285
Issue: 3
Pages: R581-93
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Publication
33160959 | J:300875
 
First Author: Faesel N
Year: 2021
Journal: Brain Res
Title: Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear.
Volume: 1751
Pages: 147199
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Publication
37664637 | J:341109
First Author: Toth BA
Year: 2023
Journal: iScience
Title: Dopamine release in the nucleus accumbens promotes REM sleep and cataplexy.
Volume: 26
Issue: 9
Pages: 107613
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Publication
20039943 | J:171793
First Author: España RA
Year: 2010
Journal: Eur J Neurosci
Title: The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system.
Volume: 31
Issue: 2
Pages: 336-48
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Publication
17284193 | J:118628
First Author: Blumberg MS
Year: 2007
Journal: Eur J Neurosci
Title: Developmental divergence of sleep-wake patterns in orexin knockout and wild-type mice.
Volume: 25
Issue: 2
Pages: 512-8
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Publication
19193905 | J:144940
First Author: Thankachan S
Year: 2009
Journal: J Neurosci
Title: Activity of pontine neurons during sleep and cataplexy in hypocretin knock-out mice.
Volume: 29
Issue: 5
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