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Search results 1 to 100 out of 397 for Hdac4

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:3587989
Assay Type: RNA in situ
Annotation Date: 2005-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3587994
Age: embryonic day 17.5
Note: Expression was detected in the bone, muscle and connective tissue of the hand.
Specimen Label: 4A HDAC4
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3587989
Assay Type: RNA in situ
Annotation Date: 2005-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3587994
Age: embryonic day 17.5
Note: Expression was detected in the bone, muscle and connective tissue of the hand.
Specimen Label: 4A HDAC4
Detected: true
Specimen Num: 1
Publication
First Author: Penrod RD
Year: 2018
Journal: Addict Biol
Title: Novel role and regulation of HDAC4 in cocaine-related behaviors.
Volume: 23
Issue: 2
Pages: 653-664
Publication  
First Author: Renzini A
Year: 2018
Journal: Front Physiol
Title: HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors.
Volume: 9
Pages: 1387
Publication
First Author: Crow M
Year: 2015
Journal: FASEB J
Title: HDAC4 is required for inflammation-associated thermal hypersensitivity.
Volume: 29
Issue: 8
Pages: 3370-8
Publication
First Author: Hohl M
Year: 2013
Journal: J Clin Invest
Title: HDAC4 controls histone methylation in response to elevated cardiac load.
Volume: 123
Issue: 3
Pages: 1359-70
Publication
First Author: Choi MC
Year: 2014
Journal: EMBO Rep
Title: HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration.
Volume: 15
Issue: 11
Pages: 1175-83
Publication
First Author: Pigna E
Year: 2018
Journal: Skelet Muscle
Title: HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses.
Volume: 8
Issue: 1
Pages: 6
Publication      
First Author: Funato, H
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission of Hdac4 allele.
Publication
First Author: Obri A
Year: 2014
Journal: J Cell Biol
Title: HDAC4 integrates PTH and sympathetic signaling in osteoblasts.
Volume: 205
Issue: 6
Pages: 771-80
Publication
First Author: Yang D
Year: 2018
Journal: Cardiovasc Res
Title: HDAC4 regulates vascular inflammation via activation of autophagy.
Volume: 114
Issue: 7
Pages: 1016-1028
Publication
First Author: Chen B
Year: 2009
Journal: Science
Title: HDAC4 regulates neuronal survival in normal and diseased retinas.
Volume: 323
Issue: 5911
Pages: 256-9
Publication
First Author: Nakatani T
Year: 2018
Journal: J Bone Miner Res
Title: The Deletion of Hdac4 in Mouse Osteoblasts Influences Both Catabolic and Anabolic Effects in Bone.
Volume: 33
Issue: 7
Pages: 1362-1375
Publication  
First Author: Nishimori S
Year: 2019
Journal: JCI Insight
Title: PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy.
Volume: 4
Issue: 5
Publication
First Author: Liu Q
Year: 2017
Journal: Oncotarget
Title: HDAC4 is expressed on multiple T cell lineages but dispensable for their development and function.
Volume: 8
Issue: 11
Pages: 17562-17572
Publication
First Author: Zhou J
Year: 2015
Journal: Biochim Biophys Acta
Title: Mitogen-activated protein kinase p38 induces HDAC4 degradation in hypertrophic chondrocytes.
Volume: 1853
Issue: 2
Pages: 370-376
Publication
First Author: Cui H
Year: 2013
Journal: J Clin Invest
Title: Eating disorder predisposition is associated with ESRRA and HDAC4 mutations.
Volume: 123
Issue: 11
Pages: 4706-13
Publication
First Author: Lu W
Year: 2015
Journal: Nat Immunol
Title: The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema.
Volume: 16
Issue: 11
Pages: 1185-94
Publication
First Author: Marroncelli N
Year: 2018
Journal: Sci Rep
Title: HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes.
Volume: 8
Issue: 1
Pages: 3448
Publication
First Author: Sando R 3rd
Year: 2012
Journal: Cell
Title: HDAC4 governs a transcriptional program essential for synaptic plasticity and memory.
Volume: 151
Issue: 4
Pages: 821-34
Publication
First Author: Wang H
Year: 2019
Journal: J Cell Physiol
Title: Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression.
Volume: 234
Issue: 3
Pages: 2730-2740
Publication
First Author: Luo L
Year: 2019
Journal: Cell Rep
Title: HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70.
Volume: 29
Issue: 3
Pages: 749-763.e12
Publication
First Author: Cohen TJ
Year: 2007
Journal: J Biol Chem
Title: The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming.
Volume: 282
Issue: 46
Pages: 33752-9
Publication
First Author: Cohen TJ
Year: 2009
Journal: FASEB J
Title: The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity.
Volume: 23
Issue: 1
Pages: 99-106
Publication
First Author: Li J
Year: 2012
Journal: Nat Med
Title: Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia.
Volume: 18
Issue: 5
Pages: 783-90
Publication
First Author: Mielcarek M
Year: 2013
Journal: PLoS Biol
Title: HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.
Volume: 11
Issue: 11
Pages: e1001717
Publication
First Author: Mielcarek M
Year: 2013
Journal: PLoS One
Title: HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.
Volume: 8
Issue: 11
Pages: e80849
Publication
First Author: Zhang LX
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: Specific inhibition of HDAC4 in cardiac progenitor cells enhances myocardial repairs.
Volume: 307
Issue: 4
Pages: C358-72
Publication
First Author: Matsushima S
Year: 2013
Journal: Circ Res
Title: Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy.
Volume: 112
Issue: 4
Pages: 651-63
Publication
First Author: Gupta MP
Year: 2008
Journal: J Biol Chem
Title: HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.
Volume: 283
Issue: 15
Pages: 10135-46
Publication
First Author: Ozcan L
Year: 2016
Journal: Cell Rep
Title: Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.
Volume: 15
Issue: 10
Pages: 2214-2225
Publication
First Author: Shimizu E
Year: 2010
Journal: J Biol Chem
Title: HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression.
Volume: 285
Issue: 13
Pages: 9616-26
Publication  
First Author: Nakatani T
Year: 2016
Journal: Bone
Title: MMP-13 is one of the critical mediators of the effect of HDAC4 deletion on the skeleton.
Volume: 90
Pages: 142-51
Publication
First Author: Rajan I
Year: 2009
Journal: PLoS One
Title: Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development.
Volume: 4
Issue: 8
Pages: e6612
Publication
First Author: Zhang LX
Year: 2018
Journal: J Appl Physiol (1985)
Title: Transgenic overexpression of active HDAC4 in the heart attenuates cardiac function and exacerbates remodeling in infarcted myocardium.
Volume: 125
Issue: 6
Pages: 1968-1978
Publication
First Author: Liu Y
Year: 2013
Journal: J Physiol
Title: Opposing HDAC4 nuclear fluxes due to phosphorylation by β-adrenergic activated protein kinase A or by activity or Epac activated CaMKII in skeletal muscle fibres.
Volume: 591
Issue: 14
Pages: 3605-23
Publication
First Author: Liu Y
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: NOX2-dependent ROS is required for HDAC5 nuclear efflux and contributes to HDAC4 nuclear efflux during intense repetitive activity of fast skeletal muscle fibers.
Volume: 303
Issue: 3
Pages: C334-47
Publication  
First Author: Ha N
Year: 2022
Journal: Front Physiol
Title: Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development.
Volume: 13
Pages: 819619
Publication  
First Author: Davis KC
Year: 2020
Journal: Front Neurosci
Title: Behavioral Alterations in Mice Carrying Homozygous HDAC4 A778T Missense Mutation Associated With Eating Disorder.
Volume: 14
Pages: 139
Publication
First Author: Backs J
Year: 2006
Journal: Circ Res
Title: Control of cardiac growth by histone acetylation/deacetylation.
Volume: 98
Issue: 1
Pages: 15-24
Publication
First Author: Kim MS
Year: 2012
Journal: J Neurosci
Title: An essential role for histone deacetylase 4 in synaptic plasticity and memory formation.
Volume: 32
Issue: 32
Pages: 10879-86
GXD Expression
Probe: MGI:6473148
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6473215
Age: embryonic day 18.5
Image: 6A Smad2;Smad3<-/->
Note: Expression was greatly diminished in the growth plate of the double mutant compared with control. The percentage of cells expressing nuclear Hdac4 was significantly decreased at the border of the prehypertrophic and lower columnar zones of the double mutant compared to either Smad2 or Smad3<-/->.
Specimen Label: 6A Smad2;Smad3<-/->
Detected: true
Specimen Num: 4
Publication  
First Author: Finke D
Year: 2021
Journal: J Mol Cell Cardiol
Title: Histone deacetylase 4 deletion broadly affects cardiac epigenetic repression and regulates transcriptional susceptibility via H3K9 methylation.
Volume: 162
Pages: 119-129
Publication  
First Author: Pigna E
Year: 2019
Journal: EBioMedicine
Title: Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis.
Volume: 40
Pages: 717-732
Publication
First Author: Gomis-Coloma C
Year: 2018
Journal: J Cell Biol
Title: Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells.
Volume: 217
Issue: 4
Pages: 1249-1268
Publication
First Author: Vega RB
Year: 2004
Journal: Cell
Title: Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.
Volume: 119
Issue: 4
Pages: 555-66
Publication
First Author: Price V
Year: 2013
Journal: J Neurosci Res
Title: Conditional deletion of histone deacetylase-4 in the central nervous system has no major effect on brain architecture or neuronal viability.
Volume: 91
Issue: 3
Pages: 407-15
Publication  
First Author: Wein MN
Year: 2016
Journal: Nat Commun
Title: SIKs control osteocyte responses to parathyroid hormone.
Volume: 7
Pages: 13176
Publication  
First Author: Meyers CMG
Year: 2022
Journal: Bone
Title: Histone deacetylase 5 is a phosphorylation substrate of protein kinase D in osteoclasts.
Volume: 159
Pages: 116393
Publication
First Author: Lehmann LH
Year: 2018
Journal: Nat Med
Title: A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.
Volume: 24
Issue: 1
Pages: 62-72
Publication    
First Author: Velasco-Aviles S
Year: 2022
Journal: Elife
Title: A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.
Volume: 11
Publication
First Author: Williams AH
Year: 2009
Journal: Science
Title: MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.
Volume: 326
Issue: 5959
Pages: 1549-54
Publication
First Author: Sato T
Year: 2020
Journal: Nat Commun
Title: A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction.
Volume: 11
Issue: 1
Pages: 3282
Publication
First Author: Choi MC
Year: 2012
Journal: Mol Cell
Title: A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program.
Volume: 47
Issue: 1
Pages: 122-32
Publication
First Author: Lutter M
Year: 2017
Journal: Biol Psychiatry
Title: The Eating-Disorder Associated HDAC4A778T Mutation Alters Feeding Behaviors in Female Mice.
Volume: 81
Issue: 9
Pages: 770-777
Publication
First Author: Cernotta N
Year: 2011
Journal: Mol Biol Cell
Title: Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility.
Volume: 22
Issue: 2
Pages: 278-89
Publication
First Author: Huang YH
Year: 2015
Journal: PLoS One
Title: Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4.
Volume: 10
Issue: 8
Pages: e0136453
Publication
First Author: Saha P
Year: 2019
Journal: J Neurotrauma
Title: Histone Deacetylase 4 Downregulation Elicits Post-Traumatic Psychiatric Disorders through Impairment of Neurogenesis.
Volume: 36
Issue: 23
Pages: 3284-3296
Publication
First Author: Wu Q
Year: 2017
Journal: Mol Neurobiol
Title: Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease.
Volume: 54
Issue: 9
Pages: 6970-6983
Publication
First Author: Di Giorgio E
Year: 2013
Journal: Mol Cell Biol
Title: MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.
Volume: 33
Issue: 22
Pages: 4473-91
Publication
First Author: Kim SJ
Year: 2022
Journal: Nature
Title: Kinase signalling in excitatory neurons regulates sleep quantity and depth.
Volume: 612
Issue: 7940
Pages: 512-518
Publication
First Author: Ago T
Year: 2008
Journal: Cell
Title: A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy.
Volume: 133
Issue: 6
Pages: 978-93
Publication
First Author: Asano F
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice.
Volume: 120
Issue: 11
Pages: e2218209120
Publication  
First Author: Yuan H
Year: 2016
Journal: Neurobiol Dis
Title: Nuclear translocation of histone deacetylase 4 induces neuronal death in stroke.
Volume: 91
Pages: 182-93
Publication
First Author: Ling S
Year: 2012
Journal: Circulation
Title: CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A.
Volume: 126
Issue: 25
Pages: 3028-40
Publication
First Author: Lemercier C
Year: 2000
Journal: J Biol Chem
Title: mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.
Volume: 275
Issue: 20
Pages: 15594-9
Publication
First Author: Sailaja BS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4.
Volume: 109
Issue: 52
Pages: E3687-95
Publication
First Author: Chen Y
Year: 2014
Journal: J Neurosci
Title: Regulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for histone deacetylase 4.
Volume: 34
Issue: 46
Pages: 15327-39
Publication
First Author: Litke C
Year: 2018
Journal: J Biol Chem
Title: Histone deacetylase 4 shapes neuronal morphology via a mechanism involving regulation of expression of vascular endothelial growth factor D.
Volume: 293
Issue: 21
Pages: 8196-8207
Publication  
First Author: Chen W
Year: 2016
Journal: Int J Mol Sci
Title: MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression.
Volume: 17
Issue: 9
Publication
First Author: Luan B
Year: 2014
Journal: Cell Metab
Title: Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4.
Volume: 19
Issue: 6
Pages: 1058-65
Publication
First Author: Zhang T
Year: 2007
Journal: J Biol Chem
Title: CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses.
Volume: 282
Issue: 48
Pages: 35078-87
Publication
First Author: Tang H
Year: 2009
Journal: Mol Biol Cell
Title: A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression.
Volume: 20
Issue: 4
Pages: 1120-31
Publication
First Author: Trazzi S
Year: 2016
Journal: Hum Mol Genet
Title: HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.
Volume: 25
Issue: 18
Pages: 3887-3907
Publication
First Author: Jeong BC
Year: 2004
Journal: Mol Endocrinol
Title: Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase.
Volume: 18
Issue: 1
Pages: 13-25
Publication
First Author: Backs J
Year: 2008
Journal: Mol Cell Biol
Title: Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.
Volume: 28
Issue: 10
Pages: 3437-45
Publication
First Author: Abend A
Year: 2017
Journal: EMBO Rep
Title: Salt-inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification.
Volume: 18
Issue: 7
Pages: 1166-1185
Publication
First Author: Bongers KS
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.
Volume: 305
Issue: 7
Pages: E907-15
Publication
First Author: Yang Q
Year: 2015
Journal: Mol Cell Biol
Title: Cross talk between histone deacetylase 4 and STAT6 in the transcriptional regulation of arginase 1 during mouse dendritic cell differentiation.
Volume: 35
Issue: 1
Pages: 63-75
HT Experiment
Series Id: GSE62405
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Kang H
Year: 2021
Journal: J Pathol
Title: The loss of histone deacetylase 4 in macrophages exacerbates hepatic and adipose tissue inflammation in male but not in female mice with diet-induced non-alcoholic steatohepatitis.
Volume: 255
Issue: 3
Pages: 319-329
Publication
First Author: Kang JS
Year: 2005
Journal: EMBO J
Title: Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.
Volume: 24
Issue: 14
Pages: 2543-55
Publication
First Author: Moresi V
Year: 2010
Journal: Cell
Title: Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.
Volume: 143
Issue: 1
Pages: 35-45
Publication
First Author: Niu Y
Year: 2017
Journal: Biochim Biophys Acta
Title: Exercise-induced GLUT4 transcription via inactivation of HDAC4/5 in mouse skeletal muscle in an AMPKα2-dependent manner.
Volume: 1863
Issue: 9
Pages: 2372-2381
Publication
First Author: Micheli L
Year: 2005
Journal: Mol Cell Biol
Title: PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.
Volume: 25
Issue: 6
Pages: 2242-59
Publication
First Author: McKinsey TA
Year: 2006
Journal: Mol Biol Cell
Title: Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK.
Volume: 17
Issue: 1
Pages: 438-47
Publication
First Author: Kozhemyakina E
Year: 2009
Journal: Mol Cell Biol
Title: Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.
Volume: 29
Issue: 21
Pages: 5751-62
Publication
First Author: Pan Z
Year: 2008
Journal: Dev Dyn
Title: Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.
Volume: 237
Issue: 2
Pages: 316-27
Publication
First Author: Arnold MA
Year: 2007
Journal: Dev Cell
Title: MEF2C transcription factor controls chondrocyte hypertrophy and bone development.
Volume: 12
Issue: 3
Pages: 377-89