Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao J |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson's Disease Pathology in Mice. |
Volume: |
24 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Gracia-Hernandez M |
Year: |
2024 |
Journal: |
J Exp Clin Cancer Res |
Title: |
Targeting HDAC6 improves anti-CD47 immunotherapy. |
Volume: |
43 |
Issue: |
1 |
Pages: |
60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beurel E |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
HDAC6 regulates LPS-tolerance in astrocytes. |
Volume: |
6 |
Issue: |
10 |
Pages: |
e25804 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sánchez de Diego A |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
Dido3-dependent HDAC6 targeting controls cilium size. |
Volume: |
5 |
|
Pages: |
3500 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perez M |
Year: |
2009 |
Journal: |
J Neurochem |
Title: |
Tau--an inhibitor of deacetylase HDAC6 function. |
Volume: |
109 |
Issue: |
6 |
Pages: |
1756-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen PB |
Year: |
2013 |
Journal: |
Elife |
Title: |
Hdac6 regulates Tip60-p400 function in stem cells. |
Volume: |
2 |
|
Pages: |
e01557 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tseng JH |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. |
Volume: |
20 |
Issue: |
9 |
Pages: |
2169-2183 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi SJ |
Year: |
2016 |
Journal: |
EMBO J |
Title: |
HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I. |
Volume: |
35 |
Issue: |
4 |
Pages: |
429-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan B |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
HDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophages. |
Volume: |
9 |
Issue: |
10 |
Pages: |
e110718 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lieber AD |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Loss of HDAC6 alters gut microbiota and worsens obesity. |
Volume: |
33 |
Issue: |
1 |
Pages: |
1098-1109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin YH |
Year: |
2022 |
Journal: |
J Clin Invest |
Title: |
HDAC6 modulates myofibril stiffness and diastolic function of the heart. |
Volume: |
132 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Phorl S |
Year: |
2022 |
Journal: |
Cancer Sci |
Title: |
Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis. |
Volume: |
113 |
Issue: |
7 |
Pages: |
2311-2322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee YS |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. |
Volume: |
68 |
Issue: |
18 |
Pages: |
7561-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages. |
Volume: |
11 |
|
Pages: |
1776 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tran AD |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. |
Volume: |
120 |
Issue: |
Pt 8 |
Pages: |
1469-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JY |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. |
Volume: |
29 |
Issue: |
5 |
Pages: |
969-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu T |
Year: |
2016 |
Journal: |
Neurobiol Aging |
Title: |
HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway. |
Volume: |
37 |
|
Pages: |
91-102 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Benoy V |
Year: |
2018 |
Journal: |
Brain |
Title: |
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease. |
Volume: |
141 |
Issue: |
3 |
Pages: |
673-687 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2017 |
Journal: |
Protein Cell |
Title: |
Overexpression of Hdac6 extends reproductive lifespan in mice. |
Volume: |
8 |
Issue: |
5 |
Pages: |
360-364 |
|
•
•
•
•
•
|
Publication |
First Author: |
Núñez-Andrade N |
Year: |
2016 |
Journal: |
J Cell Sci |
Title: |
HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes. |
Volume: |
129 |
Issue: |
7 |
Pages: |
1305-1311 |
|
•
•
•
•
•
|
Publication |
First Author: |
Osseni A |
Year: |
2020 |
Journal: |
J Cell Biol |
Title: |
HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions. |
Volume: |
219 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ranjbarvaziri S |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice. |
Volume: |
15 |
Issue: |
1 |
Pages: |
1352 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie S |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
HDAC6 regulates antibody-dependent intracellular neutralization of viruses via deacetylation of TRIM21. |
Volume: |
295 |
Issue: |
42 |
Pages: |
14343-14351 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukada M |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Loss of deacetylation activity of Hdac6 affects emotional behavior in mice. |
Volume: |
7 |
Issue: |
2 |
Pages: |
e30924 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picci C |
Year: |
2020 |
Journal: |
Exp Neurol |
Title: |
HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice. |
Volume: |
328 |
|
Pages: |
113281 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mobley RJ |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition. |
Volume: |
18 |
Issue: |
10 |
Pages: |
2387-2400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang M |
Year: |
2014 |
Journal: |
Mol Cell |
Title: |
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. |
Volume: |
55 |
Issue: |
1 |
Pages: |
31-46 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190490 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Hdac6 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190490 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Hdac6 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190490 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Hdac6 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190490 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Hdac6 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190490 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Hdac6 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190490 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Hdac6 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6174738 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190490 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Hdac6 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magupalli VG |
Year: |
2020 |
Journal: |
Science |
Title: |
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. |
Volume: |
369 |
Issue: |
6510 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Govindarajan N |
Year: |
2013 |
Journal: |
EMBO Mol Med |
Title: |
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease. |
Volume: |
5 |
Issue: |
1 |
Pages: |
52-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
d'Ydewalle C |
Year: |
2011 |
Journal: |
Nat Med |
Title: |
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease. |
Volume: |
17 |
Issue: |
8 |
Pages: |
968-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenjack J |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
HDAC6 depletion improves cystic fibrosis mouse airway responses to bacterial challenge. |
Volume: |
9 |
Issue: |
1 |
Pages: |
10282 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HJ |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. |
Volume: |
464 |
Issue: |
4 |
Pages: |
1235-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boyault C |
Year: |
2007 |
Journal: |
Genes Dev |
Title: |
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. |
Volume: |
21 |
Issue: |
17 |
Pages: |
2172-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukuda T |
Year: |
2016 |
Journal: |
EMBO Rep |
Title: |
Rescue of CAMDI deletion-induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor. |
Volume: |
17 |
Issue: |
12 |
Pages: |
1785-1798 |
|
•
•
•
•
•
|
Publication |
First Author: |
Demos-Davies KM |
Year: |
2014 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling. |
Volume: |
307 |
Issue: |
2 |
Pages: |
H252-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung S |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression. |
Volume: |
503 |
Issue: |
1 |
Pages: |
285-290 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalinski AL |
Year: |
2019 |
Journal: |
J Cell Biol |
Title: |
Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. |
Volume: |
218 |
Issue: |
6 |
Pages: |
1871-1890 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gal J |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation. |
Volume: |
288 |
Issue: |
21 |
Pages: |
15035-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2022 |
Journal: |
J Neurosci |
Title: |
HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling. |
Volume: |
42 |
Issue: |
42 |
Pages: |
7862-7874 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maharaj K |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
HDAC6 Inhibition Alleviates CLL-Induced T-Cell Dysfunction and Enhances Immune Checkpoint Blockade Efficacy in the Eμ-TCL1 Model. |
Volume: |
11 |
|
Pages: |
590072 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park SY |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation. |
Volume: |
494 |
Issue: |
1-2 |
Pages: |
51-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee SI |
Year: |
2024 |
Journal: |
Biochem Biophys Res Commun |
Title: |
HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320. |
Volume: |
691 |
|
Pages: |
149320 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalveram B |
Year: |
2008 |
Journal: |
J Cell Sci |
Title: |
The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition. |
Volume: |
121 |
Issue: |
Pt 24 |
Pages: |
4079-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wickström SA |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. |
Volume: |
29 |
Issue: |
1 |
Pages: |
131-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guan D |
Year: |
2024 |
Journal: |
Cell Metab |
Title: |
Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss. |
Volume: |
36 |
Issue: |
4 |
Pages: |
857-876.e10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tadenev ALD |
Year: |
2024 |
Journal: |
J Peripher Nerv Syst |
Title: |
Lack of effect from genetic deletion of Hdac6 in a humanized mouse model of CMT2D. |
Volume: |
29 |
Issue: |
2 |
Pages: |
213-220 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corey DA |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Alleviation of depression-like behavior in a cystic fibrosis mouse model by Hdac6 depletion. |
Volume: |
10 |
Issue: |
1 |
Pages: |
16278 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
HDAC6 Mediates Macrophage iNOS Expression and Excessive Nitric Oxide Production in the Blood During Endotoxemia. |
Volume: |
11 |
|
Pages: |
1893 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaluza D |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin. |
Volume: |
30 |
Issue: |
20 |
Pages: |
4142-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taes I |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS. |
Volume: |
22 |
Issue: |
9 |
Pages: |
1783-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lundh M |
Year: |
2019 |
Journal: |
EMBO Rep |
Title: |
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue. |
Volume: |
20 |
Issue: |
8 |
Pages: |
e48216 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishiba R |
Year: |
2019 |
Journal: |
J Mol Histol |
Title: |
Faster regeneration associated to high expression of Fam65b and Hdac6 in dysferlin-deficient mouse. |
Volume: |
50 |
Issue: |
4 |
Pages: |
375-387 |
|
•
•
•
•
•
|
Publication |
First Author: |
Espallergues J |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience. |
Volume: |
32 |
Issue: |
13 |
Pages: |
4400-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ota S |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia. |
Volume: |
25 |
Issue: |
19 |
Pages: |
4227-4243 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu W |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e49418 |
|
•
•
•
•
•
|
Publication |
First Author: |
Onishi T |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
A novel orally active HDAC6 inhibitor T-518 shows a therapeutic potential for Alzheimer's disease and tauopathy in mice. |
Volume: |
11 |
Issue: |
1 |
Pages: |
15423 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bobrowska A |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e20696 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang D |
Year: |
2015 |
Journal: |
Protein Cell |
Title: |
Overexpression of Hdac6 enhances resistance to virus infection in embryonic stem cells and in mice. |
Volume: |
6 |
Issue: |
2 |
Pages: |
152-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deakin NO |
Year: |
2014 |
Journal: |
J Cell Biol |
Title: |
Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration. |
Volume: |
206 |
Issue: |
3 |
Pages: |
395-413 |
|
•
•
•
•
•
|
Publication |
First Author: |
Purev E |
Year: |
2009 |
Journal: |
Mol Biol Cell |
Title: |
c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes. |
Volume: |
20 |
Issue: |
18 |
Pages: |
4021-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fusco C |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. |
Volume: |
7 |
Issue: |
7 |
Pages: |
e40440 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bitler BG |
Year: |
2017 |
Journal: |
Nat Cell Biol |
Title: |
ARID1A-mutated ovarian cancers depend on HDAC6 activity. |
Volume: |
19 |
Issue: |
8 |
Pages: |
962-973 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ran J |
Year: |
2020 |
Journal: |
Dev Cell |
Title: |
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia. |
Volume: |
53 |
Issue: |
3 |
Pages: |
287-299.e5 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1152
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamemura K |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6. |
Volume: |
586 |
Issue: |
9 |
Pages: |
1379-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JY |
Year: |
2014 |
Journal: |
J Cell Sci |
Title: |
MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. |
Volume: |
127 |
Issue: |
Pt 22 |
Pages: |
4954-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2015 |
Journal: |
Neurosci Bull |
Title: |
Histone deacetylase 6 delays motor neuron degeneration by ameliorating the autophagic flux defect in a transgenic mouse model of amyotrophic lateral sclerosis. |
Volume: |
31 |
Issue: |
4 |
Pages: |
459-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. |
Volume: |
28 |
Issue: |
5 |
Pages: |
1688-701 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winkler R |
Year: |
2012 |
Journal: |
Diabetes |
Title: |
Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis. |
Volume: |
61 |
Issue: |
2 |
Pages: |
513-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boucherat O |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension. |
Volume: |
7 |
Issue: |
1 |
Pages: |
4546 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao YS |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. |
Volume: |
27 |
Issue: |
24 |
Pages: |
8637-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zanin M |
Year: |
2020 |
Journal: |
Viruses |
Title: |
Histone Deacetylase 6 Knockout Mice Exhibit Higher Susceptibility to Influenza A Virus Infection. |
Volume: |
12 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Getsy PM |
Year: |
2023 |
Journal: |
Front Physiol |
Title: |
Male histone deacetylase 6 (HDAC6) knockout mice have enhanced ventilatory responses to hypoxic challenge. |
Volume: |
14 |
|
Pages: |
1332810 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2014 |
Journal: |
Circulation |
Title: |
Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation. |
Volume: |
129 |
Issue: |
3 |
Pages: |
346-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li A |
Year: |
2018 |
Journal: |
Oncogene |
Title: |
Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3-COX2-dependent pathway. |
Volume: |
37 |
Issue: |
45 |
Pages: |
5952-5966 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan B |
Year: |
2018 |
Journal: |
Theranostics |
Title: |
Histone deacetylase 6 modulates macrophage infiltration during inflammation. |
Volume: |
8 |
Issue: |
11 |
Pages: |
2927-2938 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dhanyamraju PK |
Year: |
2015 |
Journal: |
Mol Cancer Ther |
Title: |
Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway. |
Volume: |
14 |
Issue: |
3 |
Pages: |
727-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Southwood CM |
Year: |
2007 |
Journal: |
Neurochem Res |
Title: |
Microtubule deacetylases, SirT2 and HDAC6, in the nervous system. |
Volume: |
32 |
Issue: |
2 |
Pages: |
187-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rymut SM |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6. |
Volume: |
7 |
Issue: |
1 |
Pages: |
3676 |
|
•
•
•
•
•
|