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Search results 1 to 100 out of 1888 for Hes1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
3280 | HES1
Type: gene
Organism: human
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Gene
496617 | hes1
Type: gene
Organism: frog, western clawed
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Gene
119865321 | HES1
Type: gene
Organism: dog, domestic
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Gene
29577 | Hes1
Type: gene
Organism: rat
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Gene
460942 | HES1
Type: gene
Organism: chimpanzee
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Gene
539547 | HES1
Type: gene
Organism: cattle
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Gene
769039 | HES1
Type: gene
Organism: chicken
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Gene
707140 | HES1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:104853 | Hes1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cc Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cc Hes1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cd Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cd Hes1
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cd Hes1
Specimen Label: 4Cd Hes1
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 3A Hes1
Note: Authors report expression overlapping with distribution of transgene expression.
Specimen Label: 3A Hes1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cd Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cd Hes1
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607313
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Ca Hes1
Note: Expression in neuroepithelium.
Specimen Label: 4Ca Hes1
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cc Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cc Hes1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cb Hes1
Specimen Label: 4Cb Hes1
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3275715
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Note: Expression in segmental intersomitic region.
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Note: Authors report regionalized expression overlapping with distribution of transgene expession.
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cb Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cb Hes1
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Note: Expression in nasal ectoderm.
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Note: Expression in ventral neural tube.
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7623194
Age: embryonic day 9.5
Image: 2A Hes1
Note: Expression in ventral pharyngeal region.
Specimen Label: 2A Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cb Hes1
Note: Expression in endoderm and mesoderm lateral and ventral to pharynx, including second heart field.
Specimen Label: 4Cb Hes1
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Ce Hes1
Note: Expression in endoderm lateral and ventral to pharynx.
Specimen Label: 4Ce Hes1
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4Cc Hes1
Specimen Label: 4Cc Hes1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1613317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 4A Hes1 (right)
Note: Low level expression in pericardial region.
Specimen Label: 4A Hes1 (right)
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1613313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4B Hes1 (left)
Note: Expression in dorsal pericardial wall.
Specimen Label: 4B Hes1 (left)
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6377700
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6378177
Age: embryonic day 10.5
Image: 9A Hes1 WT
Specimen Label: 9A Hes1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6377700
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6378177
Age: embryonic day 10.5
Image: 9A Hes1 Six1-/-
Note: Authors report increased expression and expansion of expressing regions.
Specimen Label: 9A Hes1 Six1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6377716
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6378196
Age: embryonic day 10.5
Image: 9C Hes1 E10.5
Specimen Label: 9C Hes1 E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6377716
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6378196
Age: embryonic day 11.5
Image: 9C Hes1 E11.5
Specimen Label: 9C Hes1 E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7423875
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757624
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7425004
Age: embryonic day 16.5
Image: 7 - Hes1
Note: A few Schwann cells show expression.
Specimen Label: 7 - Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 3A Hes1 Level a
Specimen Label: 3A Hes1 Level a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7623194
Age: embryonic day 8.5
Image: 4B Hes1 (right)
Note: Expression in mesoderm lateral to pharynx.
Specimen Label: 4B Hes1 (right)
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1670817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 3A Hes1 Level b
Note: Expression in pharyngeal region, including ectoderm.
Specimen Label: 3A Hes1 Level b
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7623194
Age: embryonic day 12.5
Image: 3B Hes1 (right)
Specimen Label: 3B Hes1 (right)
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 3A Hes1 Level a
Note: Expression in neural tube, including specific population of neurons in ventral neural tube.
Specimen Label: 3A Hes1 Level a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1634617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 4A Hes1 (left)
Note: Low level expression in distal outflow tract, superior outflow tract wall and mesenchymal cells in outflow tract.
Specimen Label: 4A Hes1 (left)
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7423875
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3561424
Stage: TS24
Assay Id: MGI:7425004
Age: embryonic day 16.5
Image: 7 - Hes1
Note: The ONL-OECs lack expression.
Specimen Label: 7 - Hes1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3265120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7623194
Age: embryonic day 12.5
Image: 3B Hes1 (left)
Specimen Label: 3B Hes1 (left)
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7423875
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425004
Age: embryonic day 16.5
Image: 7 - Hes1
Note: At least some mucosal OECs show expression.
Specimen Label: 7 - Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7423875
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7425004
Age: embryonic day 16.5
Image: 7 - Hes1
Note: Expression is seen in mesenchyme surrounding the ONL as well as by mesenchyme near both olfactory and trigeminal nerve fascicles.
Specimen Label: 7 - Hes1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7623186
Assay Type: RNA in situ
Annotation Date: 2024-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7623194
Age: embryonic day 10.5
Image: 3A Hes1 Level b
Note: Expression in neural tube, including specific population of neurons in ventral neural tube.
Specimen Label: 3A Hes1 Level b
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3038909
Assay Type: RNA in situ
Annotation Date: 2004-05-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:3039252
Age: embryonic day 11.5
Specimen Label: E11.5 Hes1
Detected: true
Specimen Num: 1
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Publication
32129527 | J:303105
First Author: Ma Z
Year: 2020
Journal: Stem Cells
Title: Hes1 deficiency causes hematopoietic stem cell exhaustion.
Volume: 38
Issue: 6
Pages: 756-768
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Publication
25784680 | J:222282
First Author: Schnell SA
Year: 2015
Journal: Blood
Title: Therapeutic targeting of HES1 transcriptional programs in T-ALL.
Volume: 125
Issue: 18
Pages: 2806-14
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Publication
27322654 | J:260238
First Author: Shang Y
Year: 2016
Journal: Nat Immunol
Title: The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation.
Volume: 17
Issue: 8
Pages: 930-7
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Publication
24300895 | J:248759
First Author: Revollo JR
Year: 2013
Journal: Sci Signal
Title: HES1 is a master regulator of glucocorticoid receptor-dependent gene expression.
Volume: 6
Issue: 304
Pages: ra103
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Publication
20545770 | J:169635
First Author: Kobayashi T
Year: 2010
Journal: Genes Cells
Title: Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling.
Volume: 15
Issue: 7
Pages: 689-98
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Publication
25234168 | J:219685
First Author: Kato T
Year: 2015
Journal: Leukemia
Title: Hes1 suppresses acute myeloid leukemia development through FLT3 repression.
Volume: 29
Issue: 3
Pages: 576-85
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Publication
30705405 | J:278756
First Author: Nishikawa Y
Year: 2019
Journal: Oncogene
Title: Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Volume: 38
Issue: 22
Pages: 4283-4296
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Publication
31015298 | J:279076
First Author: Ning F
Year: 2019
Journal: J Exp Med
Title: Hes1 attenuates type I IFN responses via VEGF-C and WDFY1.
Volume: 216
Issue: 6
Pages: 1396-1410
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Publication
16651378 | J:111228
First Author: Moriyama M
Year: 2006
Journal: J Cell Biol
Title: Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells.
Volume: 173
Issue: 3
Pages: 333-9
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Publication
10205173 | J:54662
First Author: Ohtsuka T
Year: 1999
Journal: EMBO J
Title: Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.
Volume: 18
Issue: 8
Pages: 2196-207
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Publication
17367776 | J:122509
First Author: Raetzman LT
Year: 2007
Journal: Dev Biol
Title: Hes1 is required for pituitary growth and melanotrope specification.
Volume: 304
Issue: 2
Pages: 455-66
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Publication
12399594 | J:278996
First Author: Hirata H
Year: 2002
Journal: Science
Title: Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop.
Volume: 298
Issue: 5594
Pages: 840-3
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GXD Expression
GXD Expression
   
Probe: MGI:7764048
Assay Type: RNA in situ
Annotation Date: 2024-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7764426
Age: embryonic day 13.5
Specimen Label: S6A Hes1 Pax6-aCre
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7764048
Assay Type: RNA in situ
Annotation Date: 2024-10-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7764426
Age: embryonic day 13.5
Note: Remarkable reduction of expression compared to control.
Specimen Label: S6A Hes1 Pten-cko
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7764070
Assay Type: Immunohistochemistry
Annotation Date: 2024-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7764463
Age: embryonic day 14.5
Note: Expression in retinal progenitor cells. Expression mutually exclusive with that of activated Akt1.
Specimen Label: 5A/B Hes1 Pax6-aCre
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7764070
Assay Type: Immunohistochemistry
Annotation Date: 2024-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7764463
Age: embryonic day 14.5
Note: Expression in retinal progenitor cells significantly reduced compared to control.
Specimen Label: 5A/B Hes1 Pten-cko
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
22840391 | J:317901
First Author: Bonev B
Year: 2012
Journal: Cell Rep
Title: MicroRNA-9 Modulates Hes1 ultradian oscillations by forming a double-negative feedback loop.
Volume: 2
Issue: 1
Pages: 10-8
•
•
•
•
•
Publication
37193067 | J:359959
First Author: Shao X
Year: 2023
Journal: Cell Insight
Title: A role for Hes1 in constraining germinal center B cell formation.
Volume: 2
Issue: 2
Pages: 100078
•
•
•
•
•
Publication
15870295 | J:98892
First Author: Murata K
Year: 2005
Journal: Mol Cell Biol
Title: Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1.
Volume: 25
Issue: 10
Pages: 4262-71
•
•
•
•
•
Publication
21481105 | J:186950
First Author: Noda N
Year: 2011
Journal: Genes Cells
Title: Hes1 is required for contact inhibition of cell proliferation in 3T3-L1 preadipocytes.
Volume: 16
Issue: 6
Pages: 704-13
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•
•
•
•
Publication
24486648 | J:215703
First Author: Uchida T
Year: 2014
Journal: Exp Hematol
Title: Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis.
Volume: 42
Issue: 5
Pages: 369-379.e3
•
•
•
•
•
Publication
19684110 | J:151924
First Author: Kobayashi T
Year: 2009
Journal: Genes Dev
Title: The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells.
Volume: 23
Issue: 16
Pages: 1870-5
•
•
•
•
•
Publication
20134146 | J:278911
First Author: Karlsson C
Year: 2010
Journal: Cells Tissues Organs
Title: HES1 and HES5 are dispensable for cartilage and endochondral bone formation.
Volume: 192
Issue: 1
Pages: 17-27
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•
•
•
•
Publication
21169561 | J:182889
First Author: Ichi S
Year: 2011
Journal: Mol Biol Cell
Title: Role of Pax3 acetylation in the regulation of Hes1 and Neurog2.
Volume: 22
Issue: 4
Pages: 503-12
•
•
•
•
•
Publication
23277114 | J:194992
First Author: Zhu MY
Year: 2013
Journal: Gene Expr Patterns
Title: The expression of NOTCH2, HES1 and SOX9 during mouse retinal development.
Volume: 13
Issue: 3-4
Pages: 78-83
•
•
•
•
•
Publication
37200191 | J:336180
First Author: Maeda Y
Year: 2023
Journal: Cell Rep
Title: Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21.
Volume: 42
Issue: 5
Pages: 112520
•
•
•
•
•
Publication
37172728 | J:336862
First Author: Matsushita Y
Year: 2023
Journal: J Biol Chem
Title: Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development.
Volume: 299
Issue: 6
Pages: 104805
•
•
•
•
•
Publication
18292208 | J:220954
First Author: Nakamura T
Year: 2008
Journal: Stem Cells
Title: Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells.
Volume: 26
Issue: 5
Pages: 1265-74
•
•
•
•
•
Publication
11023859 | J:64679
First Author: Zheng JL
Year: 2000
Journal: Development
Title: Hes1 is a negative regulator of inner ear hair cell differentiation.
Volume: 127
Issue: 21
Pages: 4551-60
•
•
•
•
•
Publication
20431921 | J:165061
First Author: Akimoto M
Year: 2010
Journal: Cell Tissue Res
Title: Hes1 regulates formations of the hypophyseal pars tuberalis and the hypothalamus.
Volume: 340
Issue: 3
Pages: 509-21
•
•
•
•
•
Publication
19688092 | J:152461
First Author: Dudley DD
Year: 2009
Journal: PLoS One
Title: Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.
Volume: 4
Issue: 8
Pages: e6678
•
•
•
•
•
Publication
21167918 | J:170391
 
First Author: Ogata T
Year: 2011
Journal: Neuroscience
Title: Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage.
Volume: 176
Pages: 132-41
•
•
•
•
•
Publication
23134481 | J:214049
First Author: Tan SL
Year: 2012
Journal: Genes Cells
Title: MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain.
Volume: 17
Issue: 12
Pages: 952-61
•
•
•
•
•
Publication
31721388 | J:313802
First Author: Suen WJ
Year: 2020
Journal: Stem Cells
Title: Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling.
Volume: 38
Issue: 2
Pages: 301-314
•
•
•
•
•
Publication
21093323 | J:167000
First Author: Wendorff AA
Year: 2010
Journal: Immunity
Title: Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation.
Volume: 33
Issue: 5
Pages: 671-84
•
•
•
•
•
Publication
16899237 | J:119274
First Author: Georgia S
Year: 2006
Journal: Dev Biol
Title: p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors.
Volume: 298
Issue: 1
Pages: 22-31
•
•
•
•
•
Publication
10323870 | J:55107
First Author: Tomita K
Year: 1999
Journal: Genes Dev
Title: The bHLH gene Hes1 is essential for expansion of early T cell precursors.
Volume: 13
Issue: 9
Pages: 1203-10
•
•
•
•
•
Publication
31160641 | J:278476
First Author: Matsuzaki T
Year: 2019
Journal: Sci Rep
Title: Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors.
Volume: 9
Issue: 1
Pages: 8251
•
•
•
•
•
Publication
18499474 | J:137064
First Author: Jacobsen KX
Year: 2008
Journal: Mol Cell Neurosci
Title: HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: essential role in developmental expression.
Volume: 38
Issue: 3
Pages: 349-58
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•
•
•
•
Publication
12972610 | J:85757
First Author: Gratton MO
Year: 2003
Journal: Mol Cell Biol
Title: Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms.
Volume: 23
Issue: 19
Pages: 6922-35
•
•
•
•
•
Publication
15536134 | J:94731
First Author: Aguilera C
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.
Volume: 101
Issue: 47
Pages: 16537-42
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•
•
•
•
Publication
30862660 | J:279206
First Author: Lahmann I
Year: 2019
Journal: Genes Dev
Title: Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Volume: 33
Issue: 9-10
Pages: 524-535
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•
•
•
•
Publication
17681138 | J:163127
First Author: Bai G
Year: 2007
Journal: Dev Cell
Title: Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1.
Volume: 13
Issue: 2
Pages: 283-97
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6377700
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6378177
Age: embryonic day 11.5
Specimen Label: E11.5 Hes1 WT not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6377700
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6378177
Age: embryonic day 11.5
Note: Authors report increased expression and expansion of expressing regions.
Specimen Label: E11.5 Hes1 Six1-/- not shown
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
10704388 | J:60836
First Author: Jouve C
Year: 2000
Journal: Development
Title: Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm.
Volume: 127
Issue: 7
Pages: 1421-9
•
•
•
•
•
Publication
28675662 | J:252115
First Author: Riesenberg AN
Year: 2018
Journal: Dev Dyn
Title: Separate and coincident expression of Hes1 and Hes5 in the developing mouse eye.
Volume: 247
Issue: 1
Pages: 212-221
•
•
•
•
•
Publication
21084301 | J:168497
First Author: Zanotti S
Year: 2011
Journal: J Biol Chem
Title: HES1 (hairy and enhancer of split 1) is a determinant of bone mass.
Volume: 286
Issue: 4
Pages: 2648-57
•
•
•
•
•
Publication
22649105 | J:189112
First Author: Wong GW
Year: 2012
Journal: Blood
Title: HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.
Volume: 120
Issue: 7
Pages: 1439-48
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•
•
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•
Publication
12666205 | J:82774
First Author: Wu Y
Year: 2003
Journal: Dev Dyn
Title: Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors.
Volume: 226
Issue: 4
Pages: 675-89
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•
•
•
•
Publication
16508307 | J:278751
First Author: Hatakeyama J
Year: 2006
Journal: Dev Neurosci
Title: Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems.
Volume: 28
Issue: 1-2
Pages: 92-101
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•
•
•
•
Publication
39315665 | J:355651
 
First Author: El Azhar Y
Year: 2024
Journal: Development
Title: Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.
Volume: 151
Issue: 18
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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