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Search results 1 to 100 out of 933 for Hey2

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0.053s
Type Details Score
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:7423830
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757624
Stage: TS24
Assay Id: MGI:7425000
Age: embryonic day 16.5
Image: 7 - Hey2
Note: The Schwann cells lack expression.
Specimen Label: 7 - Hey2
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:7423830
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561424
Pattern: Widespread
Stage: TS24
Assay Id: MGI:7425000
Age: embryonic day 16.5
Image: 7 - Hey2
Note: The ONL-OECs show expression.
Specimen Label: 7 - Hey2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7423830
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425000
Age: embryonic day 16.5
Image: 7 - Hey2
Note: The mucosal OECs show expression.
Specimen Label: 7 - Hey2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6438123
Assay Type: RT-PCR
Annotation Date: 2020-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6438198
Age: embryonic day 9.5
Image: 4
Specimen Label: Hey2 -211k
Detected: true
Specimen Num: 2
Publication  
First Author: Kibe K
Year: 2018
Journal: Gene Expr Patterns
Title: Hey1 and Hey2 are differently expressed during mouse tooth development.
Volume: 27
Pages: 99-105
Publication
First Author: Fischer A
Year: 2004
Journal: Mamm Genome
Title: Phenotypic variability in Hey2 -/- mice and absence of HEY2 mutations in patients with congenital heart defects or Alagille syndrome.
Volume: 15
Issue: 9
Pages: 711-6
Publication
First Author: Miao L
Year: 2018
Journal: Sci Rep
Title: Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification.
Volume: 8
Issue: 1
Pages: 2678
Publication
First Author: Donovan J
Year: 2002
Journal: Curr Biol
Title: Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice.
Volume: 12
Issue: 18
Pages: 1605-10
Publication
First Author: Mintet E
Year: 2017
Journal: Sci Rep
Title: Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice.
Volume: 7
Issue: 1
Pages: 4933
Publication
First Author: Kimura S
Year: 2022
Journal: J Dent Res
Title: HIF-2α Inhibits Ameloblast Differentiation via Hey2 in Tooth Development.
Volume: 101
Issue: 13
Pages: 1637-1644
Publication
First Author: Gessler M
Year: 2002
Journal: Curr Biol
Title: Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice.
Volume: 12
Issue: 18
Pages: 1601-4
Publication  
First Author: Li S
Year: 2008
Journal: BMC Dev Biol
Title: Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development.
Volume: 8
Pages: 20
Publication
First Author: Fischer A
Year: 2004
Journal: Genes Dev
Title: The Notch target genes Hey1 and Hey2 are required for embryonic vascular development.
Volume: 18
Issue: 8
Pages: 901-11
Publication
First Author: Doetzlhofer A
Year: 2009
Journal: Dev Cell
Title: Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti.
Volume: 16
Issue: 1
Pages: 58-69
Publication
First Author: Hayashi H
Year: 2008
Journal: PLoS One
Title: Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells.
Volume: 3
Issue: 6
Pages: e2401
Publication
First Author: Seya D
Year: 2021
Journal: Dev Growth Differ
Title: A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis.
Volume: 63
Issue: 1
Pages: 82-92
Publication
First Author: Benito-Gonzalez A
Year: 2014
Journal: J Neurosci
Title: Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling.
Volume: 34
Issue: 38
Pages: 12865-76
Publication
First Author: Watanabe Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Hey2 enhancer activity defines unipotent progenitors for left ventricular cardiomyocytes in juxta-cardiac field of early mouse embryo.
Volume: 120
Issue: 37
Pages: e2307658120
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190500
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hey2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190500
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hey2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190500
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hey2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190500
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hey2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190500
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hey2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190500
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hey2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6174817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190500
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hey2
Detected: true
Specimen Num: 7
Publication
First Author: Bezzina CR
Year: 2013
Journal: Nat Genet
Title: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Volume: 45
Issue: 9
Pages: 1044-9
Publication
First Author: Ihara D
Year: 2020
Journal: Dev Biol
Title: Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors.
Volume: 461
Issue: 2
Pages: 124-131
Publication
First Author: Veerman CC
Year: 2017
Journal: Circ Res
Title: The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity.
Volume: 121
Issue: 5
Pages: 537-548
GXD Expression    
Probe: MGI:6438125
Assay Type: RT-PCR
Annotation Date: 2020-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6438200
Age: embryonic day 9.5
Image: 4
Specimen Label: Hey2 -211k
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6438124
Assay Type: RT-PCR
Annotation Date: 2020-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6438199
Age: embryonic day 9.5
Image: 4
Specimen Label: Hey2 -211k
Detected: true
Specimen Num: 2
Publication
First Author: Zanotti S
Year: 2013
Journal: J Biol Chem
Title: Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice.
Volume: 288
Issue: 30
Pages: 21547-57
Publication
First Author: Leimeister C
Year: 1999
Journal: Mech Dev
Title: Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis.
Volume: 85
Issue: 1-2
Pages: 173-7
Publication
First Author: Hartman ME
Year: 2014
Journal: FASEB J
Title: Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.
Volume: 28
Issue: 7
Pages: 3007-15
Publication
First Author: Fischer A
Year: 2005
Journal: Mol Cell Biol
Title: Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts.
Volume: 25
Issue: 20
Pages: 8960-70
Publication
First Author: Maier MM
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes.
Volume: 275
Issue: 2
Pages: 652-60
Publication
First Author: Warren SA
Year: 2011
Journal: Mol Cell Biol
Title: Differential role of Nkx2-5 in activation of the atrial natriuretic factor gene in the developing versus failing heart.
Volume: 31
Issue: 22
Pages: 4633-45
Publication  
First Author: Guo M
Year: 2012
Journal: Front Biosci (Elite Ed)
Title: P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.
Volume: 4
Pages: 2631-44
Publication
First Author: Chen L
Year: 2012
Journal: PLoS One
Title: Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival.
Volume: 7
Issue: 2
Pages: e31005
Publication
First Author: Huang X
Year: 2022
Journal: J Biol Chem
Title: The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.
Volume: 298
Issue: 1
Pages: 101449
Publication
First Author: Fischer A
Year: 2007
Journal: Circ Res
Title: Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.
Volume: 100
Issue: 6
Pages: 856-63
Publication
First Author: Bolte C
Year: 2011
Journal: PLoS One
Title: Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development.
Volume: 6
Issue: 7
Pages: e22217
Publication
First Author: Koo BK
Year: 2005
Journal: Development
Title: Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.
Volume: 132
Issue: 15
Pages: 3459-70
Publication
First Author: Boucherat O
Year: 2012
Journal: Biol Open
Title: The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways.
Volume: 1
Issue: 7
Pages: 677-91
Publication
First Author: Heisig J
Year: 2012
Journal: PLoS Genet
Title: Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.
Volume: 8
Issue: 5
Pages: e1002728
Publication
First Author: Tian X
Year: 2017
Journal: Nat Commun
Title: Identification of a hybrid myocardial zone in the mammalian heart after birth.
Volume: 8
Issue: 1
Pages: 87
Allele
Name: hairy/enhancer-of-split related with YRPW motif 2; targeted mutation 1, Manfred Gessler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sakata Y
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2.
Volume: 99
Issue: 25
Pages: 16197-202
Publication
First Author: Sakata Y
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro.
Volume: 24
Issue: 11
Pages: 2069-74
Publication
First Author: Kokubo H
Year: 2004
Journal: Circ Res
Title: Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction.
Volume: 95
Issue: 5
Pages: 540-7
Publication
First Author: Kathiriya IS
Year: 2004
Journal: J Biol Chem
Title: Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism.
Volume: 279
Issue: 52
Pages: 54937-43
Publication
First Author: Sakata Y
Year: 2006
Journal: J Mol Cell Cardiol
Title: The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation.
Volume: 40
Issue: 2
Pages: 267-73
Publication
First Author: Kokubo H
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Hesr2 knockout mice develop aortic valve disease with advancing age.
Volume: 33
Issue: 3
Pages: e84-92
Publication
First Author: Hassan AO
Year: 2021
Journal: Cell Rep
Title: An intranasal vaccine durably protects against SARS-CoV-2 variants in mice.
Volume: 36
Issue: 4
Pages: 109452
Publication
First Author: Tang Y
Year: 2008
Journal: Circ Res
Title: Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.
Volume: 102
Issue: 6
Pages: 661-8
Publication
First Author: Black BL
Year: 2006
Journal: J Mol Cell Cardiol
Title: A single mutation causes a spectrum of cardiovascular defects: the potential role of genetic modifiers, epigenetic influences, and stochastic events in phenotypic variability.
Volume: 40
Issue: 2
Pages: 201-4
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: ovary
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1861687
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1861213
Assay Type: Northern blot
Annotation Date: 2000-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1861687
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3652942
Assay Type: RT-PCR
Annotation Date: 2006-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3653008
Age: embryonic day 9.5
Image: 4
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3652942
Assay Type: RT-PCR
Annotation Date: 2006-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3653008
Age: embryonic day 9.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5294555
Assay Type: Northern blot
Annotation Date: 2011-11-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5294584
Age: postnatal adult
Image: 3
Specimen Label: Liver
Specimen Num: 1
GXD Expression      
Probe: MGI:5294555
Assay Type: Northern blot
Annotation Date: 2011-11-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5294584
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Specimen Num: 2
GXD Expression    
Probe: MGI:5294555
Assay Type: Northern blot
Annotation Date: 2011-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5294584
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5294555
Assay Type: Northern blot
Annotation Date: 2011-11-02
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:5294584
Age: postnatal adult
Image: 3
Specimen Label: Colon
Specimen Num: 4