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Search results 1 to 100 out of 365 for Hfe

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
3077 | HFE
Type: gene
Organism: human
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Gene
29199 | Hfe
Type: gene
Organism: rat
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Gene
462489 | HFE
Type: gene
Organism: chimpanzee
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Gene
497622 | HFE
Type: gene
Organism: cattle
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Gene
100688951 | HFE
Type: gene
Organism: dog, domestic
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Gene
696129 | HFE
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:109191 | Hfe
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR031092 | HFE
Type: Family
Description: Protein HFE is a member of the major histocompatibility complex class I-like family and a negative regulator of iron absorption. Mutations in the gene encoding HFE cause hereditary hemochromatosis (HH), a hereditary disease characterised by excessive intestinal absorption of dietary iron resulting in a pathological increase in total body iron stores []. HFE interacts with transferrin receptor (TFR), a key protein involved in iron transport. An alteration in this regulatory mechanism could play a role in the pathogenesis of hereditary hemochromatosis [].HFE, while structurally homologous to MHC I, is unable to bind peptides []. However, several lines of evidence indicate that the role of HFE may extend toward a role inimmunity. HFE may influence antigen presentation [, ]. Furthermore, HFE appears to inhibit antigen-specific CD8(+) T-lymphocyte activation, probably due to altered intracellular processing of MHC I antigens [].HFE gene variants correlate with body iron levels and have shown association with cancer risk, including childhood acute lymphoblastic leukemia [, ].
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Protein
Q8R557
Organism: Mus musculus/domesticus
Length: 34  
Fragment?: true
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Gene
108783645 | HFE-AS1
Type: gene
Organism: human
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Publication
15840699 | -
First Author: de Almeida SF
Year: 2005
Journal: Blood
Title: HFE cross-talks with the MHC class I antigen presentation pathway.
Volume: 106
Issue: 3
Pages: 971-7
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Publication
24643698 | -
First Author: Reuben A
Year: 2014
Journal: Eur J Immunol
Title: The WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activation.
Volume: 44
Issue: 6
Pages: 1604-14
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Publication
9546397 | -
First Author: Lebrón JA
Year: 1998
Journal: Cell
Title: Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor.
Volume: 93
Issue: 1
Pages: 111-23
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Publication
25085015 | -
First Author: Kennedy AE
Year: 2014
Journal: Leuk Res
Title: Examination of HFE associations with childhood leukemia risk and extension to other iron regulatory genes.
Volume: 38
Issue: 9
Pages: 1055-60
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Publication
25700349 | -
First Author: Reuben A
Year: 2015
Journal: Mol Immunol
Title: T lymphocyte-derived TNF and IFN-γ repress HFE expression in cancer cells.
Volume: 65
Issue: 2
Pages: 259-66
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Publication
9396865 | J:45328
First Author: Riegert P
Year: 1998
Journal: Immunogenetics
Title: The mouse HFE gene.
Volume: 47
Issue: 2
Pages: 174-7
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Publication
18249176 | J:132134
First Author: Vujić Spasić M
Year: 2008
Journal: Cell Metab
Title: Hfe acts in hepatocytes to prevent hemochromatosis.
Volume: 7
Issue: 2
Pages: 173-8
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Publication
16491649 | J:114351
First Author: Golub MS
Year: 2005
Journal: Nutr Neurosci
Title: Movement disorders in the Hfe knockout mouse.
Volume: 8
Issue: 4
Pages: 239-44
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Publication
20837779 | J:167407
First Author: Schmidt PJ
Year: 2010
Journal: Blood
Title: Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.
Volume: 116
Issue: 25
Pages: 5679-87
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Publication
12149232 | J:78346
First Author: Ajioka RS
Year: 2002
Journal: Blood
Title: Regulation of iron absorption in Hfe mutant mice.
Volume: 100
Issue: 4
Pages: 1465-9
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Publication
9465039 | -
First Author: Feder JN
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding.
Volume: 95
Issue: 4
Pages: 1472-7
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Publication
17339458 | -
First Author: de Almeida SF
Year: 2007
Journal: J Immunol
Title: Stimulation of an unfolded protein response impairs MHC class I expression.
Volume: 178
Issue: 6
Pages: 3612-9
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Publication
8696333 | -
First Author: Feder JN
Year: 1996
Journal: Nat Genet
Title: A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis.
Volume: 13
Issue: 4
Pages: 399-408
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Publication
20177050 | J:160786
First Author: Gao J
Year: 2010
Journal: Blood
Title: Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
Volume: 115
Issue: 16
Pages: 3374-81
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Publication
12547226 | J:108597
First Author: Ahmad KA
Year: 2002
Journal: Blood Cells Mol Dis
Title: Decreased liver hepcidin expression in the Hfe knockout mouse.
Volume: 29
Issue: 3
Pages: 361-6
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Publication
22745741 | J:187935
First Author: Benesova K
Year: 2012
Journal: PLoS One
Title: Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation.
Volume: 7
Issue: 6
Pages: e39363
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Publication
9482913 | J:46169
First Author: Zhou XY
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: HFE gene knockout produces mouse model of hereditary hemochromatosis.
Volume: 95
Issue: 5
Pages: 2492-7
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Publication
15131800 | J:90494
First Author: Bensaid M
Year: 2004
Journal: Gastroenterology
Title: Multigenic control of hepatic iron loading in a murine model of hemochromatosis.
Volume: 126
Issue: 5
Pages: 1400-8
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Publication
14510961 | J:86003
First Author: Laftah AH
Year: 2003
Journal: Br J Haematol
Title: Hypoxic response of iron absorption is not affected by the Hfe gene knock-out in mice.
Volume: 123
Issue: 1
Pages: 170-2
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Publication
19348938 | J:153488
First Author: Gutiérrez L
Year: 2009
Journal: Biochim Biophys Acta
Title: Iron speciation study in Hfe knockout mice tissues: magnetic and ultrastructural characterisation.
Volume: 1792
Issue: 6
Pages: 541-7
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Publication
16688533 | J:108715
First Author: Abgueguen E
Year: 2006
Journal: Mamm Genome
Title: Differential expression of genes related to HFE and iron status in mouse duodenal epithelium.
Volume: 17
Issue: 5
Pages: 430-50
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Publication
24904118 | J:214454
First Author: Wu XG
Year: 2014
Journal: Blood
Title: HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression.
Volume: 124
Issue: 8
Pages: 1335-43
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GXD Expression
GXD Expression
     
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190502
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hfe
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190502
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hfe
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190502
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hfe
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190502
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hfe
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190502
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hfe
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190502
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hfe
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6174821
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190502
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hfe
Detected: true
Specimen Num: 7
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Publication
10557317 | J:68025
First Author: Bahram S
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism.
Volume: 96
Issue: 23
Pages: 13312-7
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Publication
12190960 | J:103290
First Author: Lebeau A
Year: 2002
Journal: Eur J Clin Invest
Title: Long-term sequelae of HFE deletion in C57BL/6 x 129/O1a mice, an animal model for hereditary haemochromatosis.
Volume: 32
Issue: 8
Pages: 603-12
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Publication
15155457 | J:92700
First Author: Chua AC
Year: 2004
Journal: Blood
Title: Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis.
Volume: 104
Issue: 5
Pages: 1519-25
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Publication
19787063 | J:153589
First Author: Rodriguez A
Year: 2009
Journal: PLoS One
Title: Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum.
Volume: 4
Issue: 9
Pages: e7212
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Publication
25283820 | J:230467
First Author: Nandar W
Year: 2014
Journal: Biochim Biophys Acta
Title: H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis.
Volume: 1842
Issue: 12 Pt A
Pages: 2413-26
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Publication
12805055 | J:115714
First Author: Miranda CJ
Year: 2003
Journal: Blood
Title: Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin.
Volume: 102
Issue: 7
Pages: 2574-80
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Publication
14673107 | J:88143
First Author: Tomatsu S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.
Volume: 100
Issue: 26
Pages: 15788-93
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Publication
12750309 | J:115716
First Author: Turoczi T
Year: 2003
Journal: Circ Res
Title: HFE mutation and dietary iron content interact to increase ischemia/reperfusion injury of the heart in mice.
Volume: 92
Issue: 11
Pages: 1240-6
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Publication
16565419 | J:112905
First Author: Constante M
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.
Volume: 291
Issue: 2
Pages: G229-37
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Publication
21349849 | J:171128
First Author: Liu Y
Year: 2011
Journal: J Biol Chem
Title: Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability.
Volume: 286
Issue: 15
Pages: 13161-70
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Publication
11226304 | J:67866
First Author: Fleming RE
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis.
Volume: 98
Issue: 5
Pages: 2707-11
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Publication
11943867 | J:76070
First Author: Trinder D
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.
Volume: 99
Issue: 8
Pages: 5622-6
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Publication
29315562 | J:263224
First Author: Nixon AM
Year: 2018
Journal: J Neurochem
Title: HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity.
Volume: 145
Issue: 4
Pages: 299-311
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Publication
12468424 | J:82942
First Author: Simpson RJ
Year: 2003
Journal: Blood
Title: Duodenal nonheme iron content correlates with iron stores in mice, but the relationship is altered by Hfe gene knock-out.
Volume: 101
Issue: 8
Pages: 3316-8
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Publication
21245482 | J:170514
First Author: Wallace DF
Year: 2011
Journal: Blood
Title: Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.
Volume: 117
Issue: 10
Pages: 2960-6
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Publication
23169885 | J:214358
First Author: Gnana-Prakasam JP
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.
Volume: 54
Issue: 1
Pages: 63-71
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Publication
22244935 | J:233280
First Author: Lee P
Year: 2012
Journal: Blood Cells Mol Dis
Title: Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6.
Volume: 48
Issue: 3
Pages: 173-8
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Publication
19715555 | J:157811
First Author: Gnana-Prakasam JP
Year: 2009
Journal: Biochem J
Title: Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger.
Volume: 424
Issue: 2
Pages: 243-52
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Publication
25609138 | J:286322
First Author: Kent P
Year: 2015
Journal: J Mol Med (Berl)
Title: Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.
Volume: 93
Issue: 5
Pages: 489-98
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Publication
12367579 | J:127833
First Author: Fergelot P
Year: 2002
Journal: Blood Cells Mol Dis
Title: Iron overload in mice expressing HFE exclusively in the intestinal villi provides evidence that HFE regulates a functional cross-talk between crypt and villi enterocytes.
Volume: 28
Issue: 3
Pages: 348-60
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QTL
MGI:3692625 | Hfem1
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:3692626 | Hfem2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:3692627 | Hfem3
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:3692628 | Hfem4
Type: QTL
Organism: mouse, laboratory
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Publication
11340100 | J:69310
First Author: Knutson MD
Year: 2001
Journal: J Nutr
Title: Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice.
Volume: 131
Issue: 5
Pages: 1459-64
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Publication
32227235 | J:317668
First Author: Demetz E
Year: 2020
Journal: Eur Heart J
Title: The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development.
Volume: 41
Issue: 40
Pages: 3949-3959
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Publication
36322932 | J:340932
First Author: Xiao X
Year: 2023
Journal: Blood
Title: Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in β-thalassemia.
Volume: 141
Issue: 4
Pages: 422-432
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Publication
15914561 | J:118862
First Author: Makui H
Year: 2005
Journal: Blood
Title: Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading.
Volume: 106
Issue: 6
Pages: 2189-95
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Publication
22531912 | J:187780
First Author: Boucherma R
Year: 2012
Journal: Eur J Immunol
Title: Loss of central and peripheral CD8+ T-cell tolerance to HFE in mouse models of human familial hemochromatosis.
Volume: 42
Issue: 4
Pages: 851-62
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Publication
12631660 | J:103071
First Author: Simpson RJ
Year: 2003
Journal: Gut
Title: Duodenal mucosal reductase in wild-type and Hfe knockout mice on iron adequate, iron deficient, and iron rich feeding.
Volume: 52
Issue: 4
Pages: 510-3
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Publication
23429074 | J:201948
First Author: Nandar W
Year: 2013
Journal: Biochim Biophys Acta
Title: A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice.
Volume: 1832
Issue: 6
Pages: 729-41
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Publication
9931446 | J:52033
First Author: Sánchez M
Year: 1998
Journal: Gene
Title: Cloning, sequencing and characterization of the rat hereditary hemochromatosis promoter: comparison of the human, mouse and rat HFE promoter regions.
Volume: 225
Issue: 1-2
Pages: 77-87
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Publication
19254567 | J:147098
First Author: Gao J
Year: 2009
Journal: Cell Metab
Title: Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
Volume: 9
Issue: 3
Pages: 217-27
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Publication
19700664 | J:153840
First Author: Nairz M
Year: 2009
Journal: Blood
Title: Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
Volume: 114
Issue: 17
Pages: 3642-51
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Protein
Q5SZ91
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Publication
9548560 | J:47098
First Author: Albig W
Year: 1998
Journal: J Cell Biochem
Title: The haemochromatosis candidate gene HFE (HLA-H) of man and mouse is located in syntenic regions within the histone gene cluster.
Volume: 69
Issue: 2
Pages: 117-26
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Publication
21059897 | J:168510
First Author: Ramos P
Year: 2011
Journal: Blood
Title: Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis.
Volume: 117
Issue: 4
Pages: 1379-89
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Protein
P70387
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
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Protein
Q8C2A6
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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Protein
Q5SZ87
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
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Publication
19824072 | J:171804
First Author: Wallace DF
Year: 2009
Journal: Hepatology
Title: Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
Volume: 50
Issue: 6
Pages: 1992-2000
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Publication
20060900 | J:165085
First Author: Hall EC 2nd
Year: 2010
Journal: Biochim Biophys Acta
Title: Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.
Volume: 1802
Issue: 4
Pages: 389-95
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Publication
31188032 | J:281986
     
First Author: Chaudhary K
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Renal Iron Accelerates the Progression of Diabetic Nephropathy in HFE (High Fe-iron) Gene Knockout Mouse Model of Iron Overload.
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Publication
17945001 | J:355765
First Author: Coppin H
Year: 2007
Journal: Genome Biol
Title: Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers.
Volume: 8
Issue: 10
Pages: R221
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Publication
17255318 | J:117889
First Author: Constante M
Year: 2007
Journal: Am J Pathol
Title: Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha.
Volume: 170
Issue: 2
Pages: 497-504
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Publication
25880808 | J:233487
First Author: Costa M
Year: 2015
Journal: PLoS One
Title: Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo.
Volume: 10
Issue: 4
Pages: e0124246
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Publication
34995689 | J:319661
First Author: Alves FM
Year: 2022
Journal: Biochim Biophys Acta Gen Subj
Title: Disruption of Hfe leads to skeletal muscle iron loading and reduction of hemoproteins involved in oxidative metabolism in a mouse model of hereditary hemochromatosis.
Volume: 1866
Issue: 3
Pages: 130082
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Publication
32726410 | J:304373
First Author: Gleitz HFE
Year: 2020
Journal: Blood
Title: Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Volume: 136
Issue: 18
Pages: 2051-2064
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Publication
31717526 | J:292910
 
First Author: Guldiken N
Year: 2019
Journal: Cells
Title: Mild Iron Overload as Seen in Individuals Homozygous for the Alpha-1 Antitrypsin Pi*Z Variant Does Not Promote Liver Fibrogenesis in HFE Knockout Mice.
Volume: 8
Issue: 11
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Publication
21355094 | J:172826
First Author: Finberg KE
Year: 2011
Journal: Blood
Title: Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
Volume: 117
Issue: 17
Pages: 4590-9
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Publication
18316026 | J:133221
First Author: Schmidt PJ
Year: 2008
Journal: Cell Metab
Title: The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.
Volume: 7
Issue: 3
Pages: 205-14
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Publication
16893896 | J:117182
First Author: Goswami T
Year: 2006
Journal: J Biol Chem
Title: Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing.
Volume: 281
Issue: 39
Pages: 28494-8
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Publication
12706501 | J:119438
First Author: Stevens RG
Year: 2003
Journal: Free Radic Biol Med
Title: Oxidative damage in colon and mammary tissue of the HFE-knockout mouse.
Volume: 34
Issue: 9
Pages: 1212-6
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Publication
26799243 | J:357704
First Author: Su XW
Year: 2016
Journal: Muscle Nerve
Title: Statins accelerate disease progression and shorten survival in SOD1(G93A) mice.
Volume: 54
Issue: 2
Pages: 284-91
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Publication
10381492 | J:78536
First Author: Levy JE
Year: 1999
Journal: Blood
Title: The C282Y mutation causing hereditary hemochromatosis does not produce a null allele.
Volume: 94
Issue: 1
Pages: 9-11
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Publication
36064805 | J:328343
First Author: Rovai A
Year: 2022
Journal: Nat Commun
Title: In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice.
Volume: 13
Issue: 1
Pages: 5215
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Publication
15098034 | J:90506
First Author: Roy CN
Year: 2004
Journal: Nat Genet
Title: An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
Volume: 36
Issue: 5
Pages: 481-5
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Publication
15257718 | J:91972
First Author: Frazer DM
Year: 2004
Journal: Br J Haematol
Title: Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE.
Volume: 126
Issue: 3
Pages: 434-6
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Publication
11875007 | J:75018
First Author: Dupic F
Year: 2002
Journal: Gastroenterology
Title: Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains.
Volume: 122
Issue: 3
Pages: 745-51
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Publication
15866286 | J:101872
First Author: Magens B
Year: 2005
Journal: Acta Histochem
Title: Nuclear iron deposits in hepatocytes of iron-loaded HFE-knock-out mice: a morphometric and immunocytochemical analysis.
Volume: 107
Issue: 1
Pages: 57-65
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Publication
17376729 | J:124470
First Author: Petrak J
Year: 2007
Journal: Int J Biochem Cell Biol
Title: Iron-independent specific protein expression pattern in the liver of HFE-deficient mice.
Volume: 39
Issue: 5
Pages: 1006-15
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