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Search results 1 to 100 out of 1660 for Hif1a

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Type Details Score
Gene
3091 | HIF1A
Type: gene
Organism: human
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Gene
746195 | HIF1A
Type: gene
Organism: chimpanzee
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Gene
374177 | HIF1A
Type: gene
Organism: chicken
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Gene
704678 | HIF1A
Type: gene
Organism: macaque, rhesus
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Gene
496583 | hif1a
Type: gene
Organism: frog, western clawed
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Gene
281814 | HIF1A
Type: gene
Organism: cattle
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Gene
29560 | Hif1a
Type: gene
Organism: rat
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Gene
480348 | HIF1A
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:106918 | Hif1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100750246 | HIF1A-AS1
Type: gene
Organism: human
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Gene
100750247 | HIF1A-AS2
Type: gene
Organism: human
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Gene
105370526 | HIF1A-AS3
Type: gene
Organism: human
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Gene
283587 | HISLA
Type: gene
Organism: human
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GXD Expression
GXD Expression
   
Probe: MGI:7328459
Assay Type: RT-PCR
Annotation Date: 2022-08-09
Strength: Present
Sex: Female
Emaps: EMAPS:3803228
Stage: TS28
Assay Id: MGI:7328467
Age: postnatal
Image: S1
Specimen Label: Hif1a control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7328459
Assay Type: RT-PCR
Annotation Date: 2022-08-09
Strength: Present
Sex: Female
Emaps: EMAPS:3803228
Stage: TS28
Assay Id: MGI:7328467
Age: postnatal
Image: S1
Specimen Label: Hif1a uKO
Detected: true
Specimen Num: 2
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Publication
28860338 | J:272785
First Author: Huang R
Year: 2017
Journal: Haematologica
Title: HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis.
Volume: 102
Issue: 11
Pages: 1956-1968
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Publication
31695081 | J:287297
First Author: Samardzija M
Year: 2019
Journal: Sci Rep
Title: Hif1a and Hif2a can be safely inactivated in cone photoreceptors.
Volume: 9
Issue: 1
Pages: 16121
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Publication
29753320 | J:334281
First Author: Cerychova R
Year: 2018
Journal: Cardiovasc Diabetol
Title: Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart.
Volume: 17
Issue: 1
Pages: 68
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Publication
24608041 | J:210247
First Author: Wang H
Year: 2014
Journal: Nat Immunol
Title: Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210.
Volume: 15
Issue: 4
Pages: 393-401
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Publication
35867798 | J:327230
First Author: Abu El Maaty MA
Year: 2022
Journal: Sci Adv
Title: Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.
Volume: 8
Issue: 29
Pages: eabo2295
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Publication
24086109 | J:201805
First Author: Eckle T
Year: 2013
Journal: PLoS Biol
Title: HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium.
Volume: 11
Issue: 9
Pages: e1001665
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Publication
21212189 | J:171540
First Author: Caprara C
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: HIF1A is essential for the development of the intermediate plexus of the retinal vasculature.
Volume: 52
Issue: 5
Pages: 2109-17
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Publication
28701304 | J:253320
First Author: Philip K
Year: 2017
Journal: FASEB J
Title: HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.
Volume: 31
Issue: 11
Pages: 4745-4758
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Publication
36247475 | J:335313
 
First Author: Heck-Swain KL
Year: 2022
Journal: Front Cardiovasc Med
Title: Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1.
Volume: 9
Pages: 970415
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Publication
29514656 | J:280346
First Author: Barben M
Year: 2018
Journal: Mol Neurodegener
Title: Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia.
Volume: 13
Issue: 1
Pages: 12
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Publication
29666476 | J:269311
First Author: Barben M
Year: 2018
Journal: Cell Death Differ
Title: Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress.
Volume: 25
Issue: 12
Pages: 2071-2085
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Publication
32768595 | J:305371
First Author: Tiwari A
Year: 2020
Journal: Gastroenterology
Title: Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
Volume: 159
Issue: 5
Pages: 1882-1897.e5
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Publication
22164238 | J:188398
First Author: Hundahl CA
Year: 2011
Journal: PLoS One
Title: Neuroglobin-deficiency exacerbates Hif1A and c-FOS response, but does not affect neuronal survival during severe hypoxia in vivo.
Volume: 6
Issue: 12
Pages: e28160
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190506
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hif1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190506
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hif1a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190506
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hif1a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190506
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hif1a
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190506
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hif1a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190506
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hif1a
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6174842
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190506
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hif1a
Detected: true
Specimen Num: 6
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Publication
19293180 | J:147359
First Author: Bertout JA
Year: 2009
Journal: Cancer Res
Title: Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model.
Volume: 69
Issue: 7
Pages: 3213-20
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Publication
15781641 | J:97164
First Author: Covello KL
Year: 2005
Journal: Cancer Res
Title: Targeted replacement of hypoxia-inducible factor-1alpha by a hypoxia-inducible factor-2alpha knock-in allele promotes tumor growth.
Volume: 65
Issue: 6
Pages: 2277-86
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Publication
16510872 | J:105812
First Author: Covello KL
Year: 2006
Journal: Genes Dev
Title: HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.
Volume: 20
Issue: 5
Pages: 557-70
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Publication
25578474 | J:221975
First Author: Forristal CE
Year: 2015
Journal: Leukemia
Title: HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.
Volume: 29
Issue: 6
Pages: 1366-78
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Publication
10074486 | J:53389
First Author: Yu AY
Year: 1999
Journal: J Clin Invest
Title: Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha.
Volume: 103
Issue: 5
Pages: 691-6
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Publication
32209468 | J:288319
First Author: Mesquita I
Year: 2020
Journal: Cell Rep
Title: The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis.
Volume: 30
Issue: 12
Pages: 4052-4064.e7
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Publication
31264974 | J:280909
First Author: Masterson JC
Year: 2019
Journal: J Clin Invest
Title: Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis.
Volume: 129
Issue: 8
Pages: 3224-3235
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Publication
8786149 | J:33863
First Author: Semenza GL
Year: 1996
Journal: Genomics
Title: Assignment of the hypoxia-inducible factor 1alpha gene to a region of conserved synteny on mouse chromosome 12 and human chromosome 14q.
Volume: 34
Issue: 3
Pages: 437-9
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Publication
29343683 | J:259999
First Author: Meng X
Year: 2018
Journal: Nat Commun
Title: Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.
Volume: 9
Issue: 1
Pages: 251
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Publication
24966332 | J:216619
First Author: Paatero I
Year: 2014
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.
Volume: 289
Issue: 32
Pages: 22459-69
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Publication
32445619 | J:317448
First Author: Ni J
Year: 2020
Journal: Immunity
Title: Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity.
Volume: 52
Issue: 6
Pages: 1075-1087.e8
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Publication
30172741 | J:267740
 
First Author: Loots GG
Year: 2018
Journal: Bone
Title: Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects.
Volume: 116
Pages: 307-314
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Publication
29483579 | J:336384
First Author: Koeppen M
Year: 2018
Journal: Nat Commun
Title: Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.
Volume: 9
Issue: 1
Pages: 816
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Publication
21685248 | J:175714
First Author: Jantsch J
Year: 2011
Journal: J Leukoc Biol
Title: Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression.
Volume: 90
Issue: 3
Pages: 551-62
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Publication
9210478 | J:41006
First Author: Wenger RH
Year: 1997
Journal: Eur J Biochem
Title: The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence.
Volume: 246
Issue: 1
Pages: 155-65
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Publication
18586877 | J:141905
First Author: Shui YB
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: HIF-1: an age-dependent regulator of lens cell proliferation.
Volume: 49
Issue: 11
Pages: 4961-70
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Publication
21606594 | J:174019
First Author: Jiang X
Year: 2011
Journal: J Clin Invest
Title: Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection.
Volume: 121
Issue: 6
Pages: 2336-49
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Publication
23494472 | J:197930
First Author: Fujisaka S
Year: 2013
Journal: Diabetologia
Title: Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice.
Volume: 56
Issue: 6
Pages: 1403-12
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Publication
35626708 | J:325159
 
First Author: Hamidi A
Year: 2022
Journal: Cells
Title: Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
Volume: 11
Issue: 10
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Publication
23095889 | J:189214
First Author: Bentovim L
Year: 2012
Journal: Development
Title: HIF1α is a central regulator of collagen hydroxylation and secretion under hypoxia during bone development.
Volume: 139
Issue: 23
Pages: 4473-83
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Publication
25505323 | J:218841
First Author: Li L
Year: 2014
Journal: J Neurosci
Title: Hypoxia inducible factor-1α (HIF-1α) is required for neural stem cell maintenance and vascular stability in the adult mouse SVZ.
Volume: 34
Issue: 50
Pages: 16713-9
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Publication
23410250 | J:225064
First Author: Candelario KM
Year: 2013
Journal: J Neurochem
Title: Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1alpha expression.
Volume: 125
Issue: 3
Pages: 420-9
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Publication
11404263 | J:107836
First Author: Shimoda LA
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Partial HIF-1alpha deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia.
Volume: 281
Issue: 1
Pages: L202-8
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Publication
11792862 | J:73981
First Author: Kline DD
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha.
Volume: 99
Issue: 2
Pages: 821-6
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Publication
32493757 | J:302525
 
First Author: Arias-Cavieres A
Year: 2020
Journal: eNeuro
Title: A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia.
Volume: 7
Issue: 3
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Publication
11818497 | J:74296
First Author: Marti HH
Year: 2002
Journal: Mol Endocrinol
Title: Isoform-specific expression of hypoxia-inducible factor-1alpha during the late stages of mouse spermiogenesis.
Volume: 16
Issue: 2
Pages: 234-43
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Publication
19144962 | J:149634
First Author: Paul C
Year: 2009
Journal: Biol Reprod
Title: A single, mild, transient scrotal heat stress causes hypoxia and oxidative stress in mouse testes, which induces germ cell death.
Volume: 80
Issue: 5
Pages: 913-9
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Publication
23593116 | J:200040
First Author: Sueoka E
Year: 2013
Journal: PLoS One
Title: Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival.
Volume: 8
Issue: 4
Pages: e57833
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Publication
31009107 | J:295889
First Author: Han J
Year: 2019
Journal: J Cell Biochem
Title: Hypoxia inducible factor-1 promotes liver fibrosis in nonalcoholic fatty liver disease by activating PTEN/p65 signaling pathway.
Volume: 120
Issue: 9
Pages: 14735-14744
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Publication
31996026 | J:304886
First Author: Karshovska E
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383.
Volume: 40
Issue: 3
Pages: 583-596
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Publication
32214220 | J:286980
First Author: Okada K
Year: 2020
Journal: Sci Rep
Title: Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling.
Volume: 10
Issue: 1
Pages: 5425
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Publication
32208814 | J:290384
First Author: Zhao C
Year: 2020
Journal: Emerg Microbes Infect
Title: Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells.
Volume: 9
Issue: 1
Pages: 691-706
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Publication
30100261 | J:270527
First Author: Li C
Year: 2018
Journal: Dev Cell
Title: PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.
Volume: 46
Issue: 4
Pages: 441-455.e8
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Publication
37044112 | J:338126
First Author: Schwarz J
Year: 2023
Journal: Eur J Immunol
Title: HIF-1α targeted deletion in myeloid cells decreases MDSC accumulation and alters microbiome in neonatal mice.
Volume: 53
Issue: 7
Pages: e2250144
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Publication
26053625 | J:224763
First Author: Fan D
Year: 2015
Journal: Nat Med
Title: Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization.
Volume: 21
Issue: 7
Pages: 808-14
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Publication
20440072 | J:161456
First Author: Cheng K
Year: 2010
Journal: J Clin Invest
Title: Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets.
Volume: 120
Issue: 6
Pages: 2171-83
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Publication
17215402 | J:117302
First Author: Milosevic J
Year: 2007
Journal: J Neurosci
Title: Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling.
Volume: 27
Issue: 2
Pages: 412-21
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Publication
37531413 | J:343618
First Author: Dery KJ
Year: 2023
Journal: Sci Transl Med
Title: Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans.
Volume: 15
Issue: 707
Pages: eadf2059
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Publication
27329220 | J:240073
 
First Author: Mirzamohammadi F
Year: 2016
Journal: Nat Commun
Title: Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling.
Volume: 7
Pages: 12047
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Publication
31105007 | J:281275
First Author: Yao Q
Year: 2019
Journal: Dev Cell
Title: Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate.
Volume: 49
Issue: 5
Pages: 748-763.e7
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Publication
20634361 | J:185918
First Author: Bohuslavová R
Year: 2010
Journal: J Appl Physiol (1985)
Title: Gene expression profiling of sex differences in HIF1-dependent adaptive cardiac responses to chronic hypoxia.
Volume: 109
Issue: 4
Pages: 1195-202
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Publication
31196952 | J:277168
First Author: Bohuslavova R
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: HIF-1α is required for development of the sympathetic nervous system.
Volume: 116
Issue: 27
Pages: 13414-13423
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Publication
30250643 | J:298190
First Author: De la Garza MM
Year: 2018
Journal: Oncotarget
Title: COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.
Volume: 9
Issue: 68
Pages: 32972-32983
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Publication
15489957 | J:93476
First Author: Karhausen J
Year: 2004
Journal: J Clin Invest
Title: Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.
Volume: 114
Issue: 8
Pages: 1098-106
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Publication
19065050 | J:144713
First Author: Cantley J
Year: 2009
Journal: J Clin Invest
Title: Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.
Volume: 119
Issue: 1
Pages: 125-35
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Publication
15128677 | J:91056
First Author: Pfander D
Year: 2004
Journal: Development
Title: Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.
Volume: 131
Issue: 10
Pages: 2497-508
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Publication
26483345 | J:298194
First Author: Akhtar S
Year: 2015
Journal: Hypertension
Title: Endothelial Hypoxia-Inducible Factor-1α Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a.
Volume: 66
Issue: 6
Pages: 1220-6
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Publication
19352007 | J:149590
First Author: Mastrogiannaki M
Year: 2009
Journal: J Clin Invest
Title: HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
Volume: 119
Issue: 5
Pages: 1159-66
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Publication
17549257 | J:122021
First Author: Wang Y
Year: 2007
Journal: J Clin Invest
Title: The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Volume: 117
Issue: 6
Pages: 1616-26
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Publication
27143681 | J:243976
First Author: Dai Z
Year: 2016
Journal: Circulation
Title: Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α.
Volume: 133
Issue: 24
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