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Search results 1 to 100 out of 360 for Hipk2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Zhou Q
Year: 2022
Journal: EBioMedicine
Title: Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling.
Volume: 85
Pages: 104274
Publication
First Author: Torrente L
Year: 2017
Journal: Oncogene
Title: Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses.
Volume: 36
Issue: 44
Pages: 6204-6212
Publication  
First Author: Xiao W
Year: 2020
Journal: JCI Insight
Title: Tubular HIPK2 is a key contributor to renal fibrosis.
Volume: 5
Issue: 17
Publication  
First Author: Cao L
Year: 2019
Journal: Sci Signal
Title: HIPK2 is necessary for type I interferon-mediated antiviral immunity.
Volume: 12
Issue: 573
Publication
First Author: Shang Y
Year: 2013
Journal: PLoS Biol
Title: Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.
Volume: 11
Issue: 4
Pages: e1001527
Publication
First Author: Jin Y
Year: 2012
Journal: Nat Med
Title: A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.
Volume: 18
Issue: 4
Pages: 580-8
Publication
First Author: Lee S
Year: 2016
Journal: Neuron
Title: Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.
Volume: 91
Issue: 1
Pages: 41-55
Publication
First Author: Valente D
Year: 2015
Journal: Oncotarget
Title: HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity.
Volume: 6
Issue: 12
Pages: 10320-34
Publication
First Author: Giraud S
Year: 2004
Journal: J Virol
Title: US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrest.
Volume: 78
Issue: 6
Pages: 2984-93
Publication
First Author: Rinaldo C
Year: 2012
Journal: Mol Cell
Title: HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.
Volume: 47
Issue: 1
Pages: 87-98
Publication
First Author: Huang R
Year: 2017
Journal: Autophagy
Title: Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Volume: 13
Issue: 10
Pages: 1722-1741
Publication
First Author: Aikawa Y
Year: 2006
Journal: EMBO J
Title: Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.
Volume: 25
Issue: 17
Pages: 3955-65
Publication
First Author: Sjölund J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Identification of Hipk2 as an essential regulator of white fat development.
Volume: 111
Issue: 20
Pages: 7373-8
Publication
First Author: Ritterhoff S
Year: 2010
Journal: EMBO J
Title: The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions.
Volume: 29
Issue: 22
Pages: 3750-61
Publication
First Author: Bitomsky N
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death.
Volume: 110
Issue: 45
Pages: E4203-12
Publication
First Author: Xu L
Year: 2019
Journal: Theranostics
Title: EGFR drives the progression of AKI to CKD through HIPK2 overexpression.
Volume: 9
Issue: 9
Pages: 2712-2726
Publication
First Author: Zhang J
Year: 2007
Journal: Nat Neurosci
Title: Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons.
Volume: 10
Issue: 1
Pages: 77-86
Publication
First Author: Choi DW
Year: 2013
Journal: Mol Cell
Title: WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation.
Volume: 51
Issue: 3
Pages: 374-85
Publication
First Author: Wiggins AK
Year: 2004
Journal: J Cell Biol
Title: Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival.
Volume: 167
Issue: 2
Pages: 257-67
Publication
First Author: Wei G
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis.
Volume: 104
Issue: 32
Pages: 13040-5
Publication
First Author: Li H
Year: 2009
Journal: Neurobiol Aging
Title: Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R.
Volume: 30
Issue: 12
Pages: 2010-20
Publication
First Author: Rui Y
Year: 2004
Journal: EMBO J
Title: Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.
Volume: 23
Issue: 23
Pages: 4583-94
Publication  
First Author: Zhang F
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: HIPK2 phosphorylates HDAC3 for NF-κB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis.
Volume: 118
Issue: 28
Publication  
First Author: Ke CY
Year: 2019
Journal: Sci Signal
Title: IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion.
Volume: 12
Issue: 593
Publication
First Author: Zhang J
Year: 2020
Journal: J Neurosci
Title: Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover.
Volume: 40
Issue: 3
Pages: 557-568
Publication
First Author: Ciarapica R
Year: 2014
Journal: Cell Death Differ
Title: Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.
Volume: 21
Issue: 2
Pages: 321-32
Publication
First Author: Gerlini R
Year: 2019
Journal: Cell Death Dis
Title: Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
Volume: 10
Issue: 10
Pages: 747
Publication
First Author: Cecchinelli B
Year: 2006
Journal: Cell Death Differ
Title: Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis.
Volume: 13
Issue: 11
Pages: 1994-7
Publication
First Author: Tsuruyama T
Year: 2010
Journal: J Leukoc Biol
Title: Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas.
Volume: 88
Issue: 1
Pages: 107-16
Publication
First Author: Isono K
Year: 2006
Journal: Mol Cell Biol
Title: Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.
Volume: 26
Issue: 7
Pages: 2758-71
Protein
Organism: Mus musculus/domesticus
Length: 1169  
Fragment?: false
Publication
First Author: Wang Y
Year: 2001
Journal: Biochim Biophys Acta
Title: Isolation and characterization of cDNAs for the protein kinase HIPK2.
Volume: 1518
Issue: 1-2
Pages: 168-72
Publication
First Author: Hofmann TG
Year: 2000
Journal: Biochimie
Title: Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.
Volume: 82
Issue: 12
Pages: 1123-7
Publication
First Author: Trapasso F
Year: 2009
Journal: DNA Cell Biol
Title: Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro.
Volume: 28
Issue: 4
Pages: 161-7
Publication
First Author: Pierantoni GM
Year: 2002
Journal: Biochem Biophys Res Commun
Title: The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues.
Volume: 290
Issue: 3
Pages: 942-7
Publication
First Author: Zhang Q
Year: 2003
Journal: Cell
Title: Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.
Volume: 115
Issue: 2
Pages: 177-86
Publication
First Author: Rattay K
Year: 2015
Journal: J Immunol
Title: Homeodomain-interacting protein kinase 2, a novel autoimmune regulator interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells.
Volume: 194
Issue: 3
Pages: 921-8
Publication  
First Author: Anzilotti S
Year: 2015
Journal: Cell Death Dis
Title: Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.
Volume: 6
Pages: e2004
Publication
First Author: Sakamoto K
Year: 2010
Journal: Mol Biol Cell
Title: Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.
Volume: 21
Issue: 16
Pages: 2966-74
Publication
First Author: Bracaglia G
Year: 2009
Journal: EMBO Rep
Title: Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis.
Volume: 10
Issue: 12
Pages: 1327-33
Publication
First Author: Kim EA
Year: 2006
Journal: J Biol Chem
Title: Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.
Volume: 281
Issue: 11
Pages: 7489-97
Publication
First Author: Inoue T
Year: 2010
Journal: FEBS Lett
Title: Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.
Volume: 584
Issue: 14
Pages: 3233-8
Publication
First Author: Kanei-Ishii C
Year: 2004
Journal: Genes Dev
Title: Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.
Volume: 18
Issue: 7
Pages: 816-29
Publication
First Author: Choi DW
Year: 2008
Journal: J Biol Chem
Title: Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1.
Volume: 283
Issue: 8
Pages: 4682-9
Publication
First Author: Cecchinelli B
Year: 2006
Journal: Mol Cell Biol
Title: Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.
Volume: 26
Issue: 12
Pages: 4746-57
Publication
First Author: Shang Y
Year: 2018
Journal: J Neurosci
Title: HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death.
Volume: 38
Issue: 16
Pages: 4006-4019
Publication
First Author: Boucher MJ
Year: 2009
Journal: Endocrinology
Title: The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.
Volume: 150
Issue: 1
Pages: 87-97
Publication
First Author: Chalazonitis A
Year: 2011
Journal: J Neurosci
Title: Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.
Volume: 31
Issue: 39
Pages: 13746-57
Publication  
First Author: Ogaki S
Year: 2011
Journal: BMC Dev Biol
Title: An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.
Volume: 11
Pages: 13
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3624092
Assay Type: RT-PCR
Annotation Date: 2006-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3629637
Age: embryonic day 12.5
Specimen Label: wt
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:3624092
Assay Type: RT-PCR
Annotation Date: 2006-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3629637
Age: embryonic day 12.5
Specimen Label: +/-
Specimen Num: 3
GXD Expression        
Probe: MGI:3624092
Assay Type: RT-PCR
Annotation Date: 2006-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3629637
Age: embryonic day 12.5
Specimen Label: -/-
Specimen Num: 4
GXD Expression      
Probe: MGI:3624095
Assay Type: Western blot
Annotation Date: 2006-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3629641
Age: embryonic day 11.5
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:3624095
Assay Type: Western blot
Annotation Date: 2006-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3629641
Age: embryonic day 11.5
Specimen Label: -/-
Specimen Num: 2
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: B
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: S
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: Lu
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: Li
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: SM
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: K
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3802539
Assay Type: Northern blot
Annotation Date: 2008-08-15
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3802540
Age: postnatal
Specimen Label: T
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:7518362
Age: embryonic day 7.0
Specimen Label: 7-day
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:7518362
Age: embryonic day 11.0
Specimen Label: 11-day
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:7518362
Age: embryonic day 15.0
Specimen Label: 15-day
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:7518362
Age: embryonic day 17.0
Specimen Label: 17-day
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:7518365
Age: embryonic day 11.5
Specimen Label: 11.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7518365
Age: embryonic day 15.5
Specimen Label: 15.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7518365
Age: embryonic day 16.5
Specimen Label: 16.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7518365
Age: embryonic day 17.5
Specimen Label: 17.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7518364
Assay Type: Northern blot
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757724
Stage: TS24
Assay Id: MGI:7518365
Age: embryonic day 16.5
Specimen Label: 16.5
Detected: true
Specimen Num: 5