Type |
Details |
Score |
Gene |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
126
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, E Southard-Smith |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
platelet derived growth factor receptor, alpha polypeptide; targeted mutation 11, Philippe Soriano |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
Southard-Smith EM |
Year: |
2011 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct Data Submission 2011/07/07 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
May-Zhang AA |
Year: |
2021 |
Journal: |
Gastroenterology |
Title: |
Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ. |
Volume: |
160 |
Issue: |
3 |
Pages: |
755-770.e26 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2020 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Platelet-derived Growth Factor-α and Neuropilin-1 Mediate Lung Fibroblast Response to Rigid Collagen Fibers. |
Volume: |
62 |
Issue: |
4 |
Pages: |
454-465 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo M |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. |
Volume: |
10 |
Issue: |
1 |
Pages: |
37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Farbehi N |
Year: |
2019 |
Journal: |
Elife |
Title: |
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ha SE |
Year: |
2022 |
Journal: |
PLoS One |
Title: |
Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers. |
Volume: |
17 |
Issue: |
5 |
Pages: |
e0261743 |
|
•
•
•
•
•
|
Publication |
First Author: |
Durnin L |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Uridine adenosine tetraphosphate is a novel neurogenic P2Y1 receptor activator in the gut. |
Volume: |
111 |
Issue: |
44 |
Pages: |
15821-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gallini R |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart. |
Volume: |
11 |
Issue: |
8 |
Pages: |
e0160930 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okada A |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Transcriptionally distinct mesenchymal stem/stromal cells circulate in fetus. |
Volume: |
512 |
Issue: |
2 |
Pages: |
326-330 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurahashi M |
Year: |
2013 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
A novel population of subepithelial platelet-derived growth factor receptor α-positive cells in the mouse and human colon. |
Volume: |
304 |
Issue: |
9 |
Pages: |
G823-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayes BJ |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e92925 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moyon S |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. |
Volume: |
35 |
Issue: |
1 |
Pages: |
4-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Endale M |
Year: |
2017 |
Journal: |
Dev Biol |
Title: |
Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development. |
Volume: |
425 |
Issue: |
2 |
Pages: |
161-175 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bloomekatz J |
Year: |
2017 |
Journal: |
Elife |
Title: |
Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2017 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Glucocorticoids Retain Bipotent Fibroblast Progenitors during Alveolar Septation in Mice. |
Volume: |
57 |
Issue: |
1 |
Pages: |
111-120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hughes AJ |
Year: |
2018 |
Journal: |
Dev Cell |
Title: |
Engineered Tissue Folding by Mechanical Compaction of the Mesenchyme. |
Volume: |
44 |
Issue: |
2 |
Pages: |
165-178.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chojnacki A |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
PDGFRα expression distinguishes GFAP-expressing neural stem cells from PDGF-responsive neural precursors in the adult periventricular area. |
Volume: |
31 |
Issue: |
26 |
Pages: |
9503-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boroviak T |
Year: |
2014 |
Journal: |
Nat Cell Biol |
Title: |
The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. |
Volume: |
16 |
Issue: |
6 |
Pages: |
516-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plusa B |
Year: |
2008 |
Journal: |
Development |
Title: |
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. |
Volume: |
135 |
Issue: |
18 |
Pages: |
3081-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makino K |
Year: |
2017 |
Journal: |
J Invest Dermatol |
Title: |
Blockade of PDGF Receptors by Crenolanib Has Therapeutic Effect in Patient Fibroblasts and in Preclinical Models of Systemic Sclerosis. |
Volume: |
137 |
Issue: |
8 |
Pages: |
1671-1681 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lo BC |
Year: |
2017 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury. |
Volume: |
57 |
Issue: |
6 |
Pages: |
651-661 |
|
•
•
•
•
•
|
Publication |
First Author: |
Collins CA |
Year: |
2011 |
Journal: |
Development |
Title: |
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. |
Volume: |
138 |
Issue: |
23 |
Pages: |
5189-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng H |
Year: |
2023 |
Journal: |
FASEB J |
Title: |
Cardiac PDGFRα(+) interstitial cells generate spontaneous inward currents that contribute to excitability in the heart. |
Volume: |
37 |
Issue: |
5 |
Pages: |
e22929 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugg KB |
Year: |
2017 |
Journal: |
FEBS Lett |
Title: |
Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy. |
Volume: |
591 |
Issue: |
5 |
Pages: |
801-809 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mueller AA |
Year: |
2016 |
Journal: |
Nature |
Title: |
Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis. |
Volume: |
540 |
Issue: |
7632 |
Pages: |
276-279 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gallini R |
Year: |
2016 |
Journal: |
Exp Cell Res |
Title: |
PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice. |
Volume: |
349 |
Issue: |
2 |
Pages: |
282-290 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurahashi M |
Year: |
2014 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles. |
Volume: |
307 |
Issue: |
6 |
Pages: |
C561-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oak P |
Year: |
2017 |
Journal: |
EMBO Mol Med |
Title: |
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease. |
Volume: |
9 |
Issue: |
11 |
Pages: |
1504-1520 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bax NA |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Cardiac malformations in Pdgfralpha mutant embryos are associated with increased expression of WT1 and Nkx2.5 in the second heart field. |
Volume: |
239 |
Issue: |
8 |
Pages: |
2307-17 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
involves: 129S4/SvJaeSor |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
involves: 129 * 129S4/SvJae * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
involves: 129S4/SvJaeSor * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/? |
Background: |
involves: 129S4/SvJaeSor * ICR |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
involves: 129S4/SvJaeSor * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
B6.129S4-Pdgfra |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
Not Specified |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/? |
Background: |
involves: 129S4/SvJaeSor |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
involves: 129S4/SvJaeSor |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra<+> |
Background: |
B6.129S4-Pdgfra/J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Baker SA |
Year: |
2013 |
Journal: |
J Physiol |
Title: |
Distribution and Ca(2+) signalling of fibroblast-like (PDGFR(+)) cells in the murine gastric fundus. |
Volume: |
591 |
Issue: |
24 |
Pages: |
6193-208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee H |
Year: |
2015 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
UTP activates small-conductance Ca2+-activated K+ channels in murine detrusor PDGFRα+ cells. |
Volume: |
309 |
Issue: |
6 |
Pages: |
F569-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Santoro SW |
Year: |
2012 |
Journal: |
Elife |
Title: |
The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. |
Volume: |
1 |
|
Pages: |
e00070 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corpening JC |
Year: |
2008 |
Journal: |
Dev Dyn |
Title: |
A Histone2BCerulean BAC transgene identifies differential expression of Phox2b in migrating enteric neural crest derivatives and enteric glia. |
Volume: |
237 |
Issue: |
4 |
Pages: |
1119-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fazilaty H |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. |
Volume: |
36 |
Issue: |
5 |
Pages: |
109484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fredriksson L |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities. |
Volume: |
180 |
Issue: |
3 |
Pages: |
1136-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gillnäs S |
Year: |
2022 |
Journal: |
Biol Open |
Title: |
Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development. |
Volume: |
11 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Florio F |
Year: |
2023 |
Journal: |
EMBO Mol Med |
Title: |
Combinatorial activation of the WNT-dependent fibrogenic program by distinct complement subunits in dystrophic muscle. |
Volume: |
15 |
Issue: |
12 |
Pages: |
e17405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rebolledo DL |
Year: |
2019 |
Journal: |
Matrix Biol |
Title: |
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β. |
Volume: |
82 |
|
Pages: |
20-37 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gata6/Gata6 Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfc/Pdgfc<+> Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfc/Pdgfc<+> Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2017 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. |
Volume: |
313 |
Issue: |
6 |
Pages: |
L1174-L1187 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Neuropilin-1 and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation. |
Volume: |
315 |
Issue: |
1 |
Pages: |
L102-L115 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2015 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice. |
Volume: |
309 |
Issue: |
5 |
Pages: |
L463-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGowan SE |
Year: |
2013 |
Journal: |
Respir Res |
Title: |
Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a. |
Volume: |
14 |
|
Pages: |
68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi Y |
Year: |
2015 |
Journal: |
Gastroenterology |
Title: |
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. |
Volume: |
149 |
Issue: |
2 |
Pages: |
420-32.e16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Artus J |
Year: |
2013 |
Journal: |
Stem Cells |
Title: |
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst. |
Volume: |
31 |
Issue: |
9 |
Pages: |
1932-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Filimonow K |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts. |
Volume: |
14 |
Issue: |
2 |
Pages: |
e0212109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perl AK |
Year: |
2009 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
FGF signaling is required for myofibroblast differentiation during alveolar regeneration. |
Volume: |
297 |
Issue: |
2 |
Pages: |
L299-308 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2012 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization. |
Volume: |
47 |
Issue: |
4 |
Pages: |
517-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Córdova-Casanova A |
Year: |
2022 |
Journal: |
Matrix Biol |
Title: |
Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle. |
Volume: |
109 |
|
Pages: |
121-139 |
|
•
•
•
•
•
|
Publication |
First Author: |
Contreras O |
Year: |
2020 |
Journal: |
J Cell Sci |
Title: |
TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts. |
Volume: |
133 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fujita R |
Year: |
2015 |
Journal: |
Stem Cells |
Title: |
Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice. |
Volume: |
33 |
Issue: |
3 |
Pages: |
962-75 |
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•
•
•
•
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Publication |
First Author: |
Mandeville I |
Year: |
2006 |
Journal: |
Am J Pathol |
Title: |
Impact of the loss of Hoxa5 function on lung alveogenesis. |
Volume: |
169 |
Issue: |
4 |
Pages: |
1312-27 |
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•
•
•
•
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Publication |
First Author: |
Wei Z |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4468 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfra/Pdgfra |
Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa5/Hoxa5 Pdgfra/Pdgfra<+> |
Background: |
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * MF1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dnmt1/Dnmt1 Pdgfra/Pdgfra<+> |
Background: |
involves: 129S4/SvJae * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee H |
Year: |
2014 |
Journal: |
J Physiol |
Title: |
Purinergic inhibitory regulation of murine detrusor muscles mediated by PDGFRα+ interstitial cells. |
Volume: |
592 |
Issue: |
6 |
Pages: |
1283-93 |
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•
•
•
•
•
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Publication |
First Author: |
Wright JH |
Year: |
2014 |
Journal: |
Int J Cancer |
Title: |
Paracrine activation of hepatic stellate cells in platelet-derived growth factor C transgenic mice: evidence for stromal induction of hepatocellular carcinoma. |
Volume: |
134 |
Issue: |
4 |
Pages: |
778-88 |
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•
•
•
•
•
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Publication |
First Author: |
Brütsch SM |
Year: |
2023 |
Journal: |
Cell Mol Life Sci |
Title: |
Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome. |
Volume: |
80 |
Issue: |
4 |
Pages: |
89 |
|
•
•
•
•
•
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Publication |
First Author: |
Kim EE |
Year: |
2023 |
Journal: |
Development |
Title: |
The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation. |
Volume: |
150 |
Issue: |
21 |
|
|
•
•
•
•
•
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Publication |
First Author: |
Van Hove L |
Year: |
2021 |
Journal: |
EMBO Rep |
Title: |
Fibrotic enzymes modulate wound-induced skin tumorigenesis. |
Volume: |
22 |
Issue: |
5 |
Pages: |
e51573 |
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•
•
•
•
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Publication |
First Author: |
Lee H |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Role of detrusor PDGFRα+ cells in mouse model of cyclophosphamide-induced detrusor overactivity. |
Volume: |
12 |
Issue: |
1 |
Pages: |
5071 |
|
•
•
•
•
•
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Publication |
First Author: |
Lee H |
Year: |
2013 |
Journal: |
J Physiol |
Title: |
Functional expression of SK channels in murine detrusor PDGFR+ cells. |
Volume: |
591 |
Issue: |
2 |
Pages: |
503-13 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pdgfa/Pdgfa Pdgfra/Pdgfra<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fgfr2/Fgfr2<+> Pdgfra/Pdgfra<+> |
Background: |
involves: 129S4/SvJaeSor |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bessonnard S |
Year: |
2019 |
Journal: |
Stem Cells |
Title: |
PDGF Signaling in Primitive Endoderm Cell Survival Is Mediated by PI3K-mTOR Through p53-Independent Mechanism. |
Volume: |
37 |
Issue: |
7 |
Pages: |
888-898 |
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•
•
•
•
•
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Publication |
First Author: |
Schrode N |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. |
Volume: |
29 |
Issue: |
4 |
Pages: |
454-67 |
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•
•
•
•
•
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Publication |
First Author: |
Farinello D |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression. |
Volume: |
9 |
Issue: |
1 |
Pages: |
1787 |
|
•
•
•
•
•
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Publication |
First Author: |
Lin J |
Year: |
2017 |
Journal: |
Stem Cell Reports |
Title: |
PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines. |
Volume: |
9 |
Issue: |
4 |
Pages: |
1062-1070 |
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•
•
•
•
•
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Publication |
First Author: |
Lee H |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα+ cells. |
Volume: |
7 |
Issue: |
1 |
Pages: |
12245 |
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•
•
•
•
•
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Publication |
First Author: |
Remaud S |
Year: |
2017 |
Journal: |
Elife |
Title: |
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain. |
Volume: |
6 |
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|
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•
•
•
•
•
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Publication |
First Author: |
Kang M |
Year: |
2013 |
Journal: |
Development |
Title: |
FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. |
Volume: |
140 |
Issue: |
2 |
Pages: |
267-79 |
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