| Type |
Details |
Score |
| Gene |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
126
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Allele |
| Name: |
platelet derived growth factor receptor, alpha polypeptide; targeted mutation 11, Philippe Soriano |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, E Southard-Smith |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2017 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Glucocorticoids Retain Bipotent Fibroblast Progenitors during Alveolar Septation in Mice. |
| Volume: |
57 |
| Issue: |
1 |
| Pages: |
111-120 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hughes AJ |
| Year: |
2018 |
| Journal: |
Dev Cell |
| Title: |
Engineered Tissue Folding by Mechanical Compaction of the Mesenchyme. |
| Volume: |
44 |
| Issue: |
2 |
| Pages: |
165-178.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ha SE |
| Year: |
2022 |
| Journal: |
PLoS One |
| Title: |
Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers. |
| Volume: |
17 |
| Issue: |
5 |
| Pages: |
e0261743 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boroviak T |
| Year: |
2014 |
| Journal: |
Nat Cell Biol |
| Title: |
The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
516-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng H |
| Year: |
2023 |
| Journal: |
FASEB J |
| Title: |
Cardiac PDGFRα(+) interstitial cells generate spontaneous inward currents that contribute to excitability in the heart. |
| Volume: |
37 |
| Issue: |
5 |
| Pages: |
e22929 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Makino K |
| Year: |
2017 |
| Journal: |
J Invest Dermatol |
| Title: |
Blockade of PDGF Receptors by Crenolanib Has Therapeutic Effect in Patient Fibroblasts and in Preclinical Models of Systemic Sclerosis. |
| Volume: |
137 |
| Issue: |
8 |
| Pages: |
1671-1681 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Endale M |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development. |
| Volume: |
425 |
| Issue: |
2 |
| Pages: |
161-175 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bloomekatz J |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lo BC |
| Year: |
2017 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury. |
| Volume: |
57 |
| Issue: |
6 |
| Pages: |
651-661 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Özsoy Ş |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
108942 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hossain MN |
| Year: |
2024 |
| Journal: |
EBioMedicine |
| Title: |
Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity. |
| Volume: |
109 |
|
| Pages: |
105421 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mueller AA |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis. |
| Volume: |
540 |
| Issue: |
7632 |
| Pages: |
276-279 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Collins CA |
| Year: |
2011 |
| Journal: |
Development |
| Title: |
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. |
| Volume: |
138 |
| Issue: |
23 |
| Pages: |
5189-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurahashi M |
| Year: |
2014 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles. |
| Volume: |
307 |
| Issue: |
6 |
| Pages: |
C561-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gallini R |
| Year: |
2016 |
| Journal: |
Exp Cell Res |
| Title: |
PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice. |
| Volume: |
349 |
| Issue: |
2 |
| Pages: |
282-290 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oak P |
| Year: |
2017 |
| Journal: |
EMBO Mol Med |
| Title: |
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease. |
| Volume: |
9 |
| Issue: |
11 |
| Pages: |
1504-1520 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sugg KB |
| Year: |
2017 |
| Journal: |
FEBS Lett |
| Title: |
Inhibition of platelet-derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy. |
| Volume: |
591 |
| Issue: |
5 |
| Pages: |
801-809 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song NN |
| Year: |
2023 |
| Journal: |
J Neurogastroenterol Motil |
| Title: |
Protein Kinase CK2 Modulates the Calcium Sensitivity of Type 3 Small-conductance Calcium-activated Potassium Channels in Colonic Platelet-derived Growth Factor Receptor Alpha-positive Cells From Streptozotocin-induced Diabetic Mice. |
| Volume: |
29 |
| Issue: |
2 |
| Pages: |
250-261 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boroviak T |
| Year: |
2015 |
| Journal: |
Dev Cell |
| Title: |
Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis. |
| Volume: |
35 |
| Issue: |
3 |
| Pages: |
366-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farbehi N |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Durnin L |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Uridine adenosine tetraphosphate is a novel neurogenic P2Y1 receptor activator in the gut. |
| Volume: |
111 |
| Issue: |
44 |
| Pages: |
15821-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo M |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ishida N |
| Year: |
2024 |
| Journal: |
Int J Med Sci |
| Title: |
Dasatinib promotes muscle differentiation and disrupts normal muscle regeneration. |
| Volume: |
21 |
| Issue: |
8 |
| Pages: |
1461-1471 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurahashi M |
| Year: |
2013 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
A novel population of subepithelial platelet-derived growth factor receptor α-positive cells in the mouse and human colon. |
| Volume: |
304 |
| Issue: |
9 |
| Pages: |
G823-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu M |
| Year: |
2023 |
| Journal: |
Stem Cell Res Ther |
| Title: |
Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
321 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gallini R |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e0160930 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Plusa B |
| Year: |
2008 |
| Journal: |
Development |
| Title: |
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. |
| Volume: |
135 |
| Issue: |
18 |
| Pages: |
3081-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2020 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Platelet-derived Growth Factor-α and Neuropilin-1 Mediate Lung Fibroblast Response to Rigid Collagen Fibers. |
| Volume: |
62 |
| Issue: |
4 |
| Pages: |
454-465 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hayes BJ |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis. |
| Volume: |
9 |
| Issue: |
3 |
| Pages: |
e92925 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bax NA |
| Year: |
2010 |
| Journal: |
Dev Dyn |
| Title: |
Cardiac malformations in Pdgfralpha mutant embryos are associated with increased expression of WT1 and Nkx2.5 in the second heart field. |
| Volume: |
239 |
| Issue: |
8 |
| Pages: |
2307-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chojnacki A |
| Year: |
2011 |
| Journal: |
J Neurosci |
| Title: |
PDGFRα expression distinguishes GFAP-expressing neural stem cells from PDGF-responsive neural precursors in the adult periventricular area. |
| Volume: |
31 |
| Issue: |
26 |
| Pages: |
9503-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moyon S |
| Year: |
2015 |
| Journal: |
J Neurosci |
| Title: |
Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
4-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okada A |
| Year: |
2019 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Transcriptionally distinct mesenchymal stem/stromal cells circulate in fetus. |
| Volume: |
512 |
| Issue: |
2 |
| Pages: |
326-330 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Southard-Smith EM |
| Year: |
2011 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Direct Data Submission 2011/07/07 |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
May-Zhang AA |
| Year: |
2021 |
| Journal: |
Gastroenterology |
| Title: |
Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ. |
| Volume: |
160 |
| Issue: |
3 |
| Pages: |
755-770.e26 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
involves: 129 * 129S4/SvJae * C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/? |
| Background: |
involves: 129S4/SvJaeSor * ICR |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
B6.129S4-Pdgfra |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/? |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra<+> |
| Background: |
B6.129S4-Pdgfra/J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Phox2b-HIST2H2BE/Cerulean)1Sout/? |
| Background: |
involves: C57BL/6 * SJL |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Santoro SW |
| Year: |
2012 |
| Journal: |
Elife |
| Title: |
The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. |
| Volume: |
1 |
|
| Pages: |
e00070 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee H |
| Year: |
2015 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
UTP activates small-conductance Ca2+-activated K+ channels in murine detrusor PDGFRα+ cells. |
| Volume: |
309 |
| Issue: |
6 |
| Pages: |
F569-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baker SA |
| Year: |
2013 |
| Journal: |
J Physiol |
| Title: |
Distribution and Ca(2+) signalling of fibroblast-like (PDGFR(+)) cells in the murine gastric fundus. |
| Volume: |
591 |
| Issue: |
24 |
| Pages: |
6193-208 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Florio F |
| Year: |
2023 |
| Journal: |
EMBO Mol Med |
| Title: |
Combinatorial activation of the WNT-dependent fibrogenic program by distinct complement subunits in dystrophic muscle. |
| Volume: |
15 |
| Issue: |
12 |
| Pages: |
e17405 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Corpening JC |
| Year: |
2008 |
| Journal: |
Dev Dyn |
| Title: |
A Histone2BCerulean BAC transgene identifies differential expression of Phox2b in migrating enteric neural crest derivatives and enteric glia. |
| Volume: |
237 |
| Issue: |
4 |
| Pages: |
1119-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rebolledo DL |
| Year: |
2019 |
| Journal: |
Matrix Biol |
| Title: |
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β. |
| Volume: |
82 |
|
| Pages: |
20-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fredriksson L |
| Year: |
2012 |
| Journal: |
Am J Pathol |
| Title: |
Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities. |
| Volume: |
180 |
| Issue: |
3 |
| Pages: |
1136-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fazilaty H |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. |
| Volume: |
36 |
| Issue: |
5 |
| Pages: |
109484 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gillnäs S |
| Year: |
2022 |
| Journal: |
Biol Open |
| Title: |
Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development. |
| Volume: |
11 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gata6/Gata6 Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfc/Pdgfc<+> Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfc/Pdgfc Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfc/Pdgfc<+> Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujita R |
| Year: |
2015 |
| Journal: |
Stem Cells |
| Title: |
Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice. |
| Volume: |
33 |
| Issue: |
3 |
| Pages: |
962-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Contreras O |
| Year: |
2020 |
| Journal: |
J Cell Sci |
| Title: |
TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts. |
| Volume: |
133 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Artus J |
| Year: |
2013 |
| Journal: |
Stem Cells |
| Title: |
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst. |
| Volume: |
31 |
| Issue: |
9 |
| Pages: |
1932-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Córdova-Casanova A |
| Year: |
2022 |
| Journal: |
Matrix Biol |
| Title: |
Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle. |
| Volume: |
109 |
|
| Pages: |
121-139 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mandeville I |
| Year: |
2006 |
| Journal: |
Am J Pathol |
| Title: |
Impact of the loss of Hoxa5 function on lung alveogenesis. |
| Volume: |
169 |
| Issue: |
4 |
| Pages: |
1312-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perl AK |
| Year: |
2009 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
FGF signaling is required for myofibroblast differentiation during alveolar regeneration. |
| Volume: |
297 |
| Issue: |
2 |
| Pages: |
L299-308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen L |
| Year: |
2012 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization. |
| Volume: |
47 |
| Issue: |
4 |
| Pages: |
517-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2015 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice. |
| Volume: |
309 |
| Issue: |
5 |
| Pages: |
L463-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2013 |
| Journal: |
Respir Res |
| Title: |
Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a. |
| Volume: |
14 |
|
| Pages: |
68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2017 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. |
| Volume: |
313 |
| Issue: |
6 |
| Pages: |
L1174-L1187 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei Z |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
4468 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McGowan SE |
| Year: |
2018 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
Neuropilin-1 and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation. |
| Volume: |
315 |
| Issue: |
1 |
| Pages: |
L102-L115 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Filimonow K |
| Year: |
2019 |
| Journal: |
PLoS One |
| Title: |
No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts. |
| Volume: |
14 |
| Issue: |
2 |
| Pages: |
e0212109 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hayashi Y |
| Year: |
2015 |
| Journal: |
Gastroenterology |
| Title: |
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. |
| Volume: |
149 |
| Issue: |
2 |
| Pages: |
420-32.e16 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfra/Pdgfra |
| Background: |
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa5/Hoxa5 Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * MF1 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dnmt1/Dnmt1 Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S4/SvJae * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim EE |
| Year: |
2023 |
| Journal: |
Development |
| Title: |
The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation. |
| Volume: |
150 |
| Issue: |
21 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee H |
| Year: |
2013 |
| Journal: |
J Physiol |
| Title: |
Functional expression of SK channels in murine detrusor PDGFR+ cells. |
| Volume: |
591 |
| Issue: |
2 |
| Pages: |
503-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee H |
| Year: |
2014 |
| Journal: |
J Physiol |
| Title: |
Purinergic inhibitory regulation of murine detrusor muscles mediated by PDGFRα+ interstitial cells. |
| Volume: |
592 |
| Issue: |
6 |
| Pages: |
1283-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee H |
| Year: |
2022 |
| Journal: |
Sci Rep |
| Title: |
Role of detrusor PDGFRα+ cells in mouse model of cyclophosphamide-induced detrusor overactivity. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
5071 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brütsch SM |
| Year: |
2023 |
| Journal: |
Cell Mol Life Sci |
| Title: |
Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome. |
| Volume: |
80 |
| Issue: |
4 |
| Pages: |
89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Herriges MJ |
| Year: |
2023 |
| Journal: |
Cell Stem Cell |
| Title: |
Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice. |
| Volume: |
30 |
| Issue: |
9 |
| Pages: |
1217-1234.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wright JH |
| Year: |
2014 |
| Journal: |
Int J Cancer |
| Title: |
Paracrine activation of hepatic stellate cells in platelet-derived growth factor C transgenic mice: evidence for stromal induction of hepatocellular carcinoma. |
| Volume: |
134 |
| Issue: |
4 |
| Pages: |
778-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Hove L |
| Year: |
2021 |
| Journal: |
EMBO Rep |
| Title: |
Fibrotic enzymes modulate wound-induced skin tumorigenesis. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
e51573 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pdgfa/Pdgfa Pdgfra/Pdgfra<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|