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Search results 1 to 100 out of 813 for Hoxa13

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0.038s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Roux M
Year: 2019
Journal: Hum Mol Genet
Title: Multifaceted Hoxa13 function in urogenital development underlies the Hand-Foot-Genital Syndrome.
Volume: 28
Issue: 10
Pages: 1671-1681
Publication
First Author: Scotti M
Year: 2012
Journal: Development
Title: Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals.
Volume: 139
Issue: 4
Pages: 731-9
Publication
First Author: Kherdjemil Y
Year: 2016
Journal: Nature
Title: Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state.
Volume: 539
Issue: 7627
Pages: 89-92
Publication  
First Author: Desanlis I
Year: 2020
Journal: J Dev Biol
Title: Transcriptional Trajectories in Mouse Limb Buds Reveal the Transition from Anterior-Posterior to Proximal-Distal Patterning at Early Limb Bud Stage.
Volume: 8
Issue: 4
Publication
First Author: Scotti M
Year: 2015
Journal: Genesis
Title: A Hoxa13:Cre mouse strain for conditional gene manipulation in developing limb, hindgut, and urogenital system.
Volume: 53
Issue: 6
Pages: 366-76
Publication
First Author: Carlson HL
Year: 2020
Journal: Genesis
Title: Development and functional characterization of a lncRNA-HIT conditional loss of function allele.
Volume: 58
Issue: 3-4
Pages: e23351
Publication
First Author: Larkins CE
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Spatiotemporal dynamics of androgen signaling underlie sexual differentiation and congenital malformations of the urethra and vagina.
Volume: 113
Issue: 47
Pages: E7510-E7517
Publication
First Author: Zheng Z
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Timing of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies.
Volume: 112
Issue: 52
Pages: E7194-203
Publication
First Author: BĂ©nazet JD
Year: 2012
Journal: Development
Title: Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds.
Volume: 139
Issue: 22
Pages: 4250-60
Publication
First Author: Delgado I
Year: 2020
Journal: Sci Adv
Title: Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb.
Volume: 6
Issue: 23
Pages: eaaz0742
Publication
First Author: Lopez-Rios J
Year: 2012
Journal: Dev Cell
Title: GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.
Volume: 22
Issue: 4
Pages: 837-48
Publication
First Author: Zhao Y
Year: 2001
Journal: Development
Title: Functional specificity of the Hoxa13 homeobox.
Volume: 128
Issue: 16
Pages: 3197-207
GXD Expression
Probe: MGI:5904285
Assay Type: RNA in situ
Annotation Date: 2017-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5904292
Age: embryonic day 12.5
Image: 2A Hoxa13
Note: Expression only in distal presumptive digit domain and in the future wrist.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6492176
Assay Type: RNA in situ
Annotation Date: 2021-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3594417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6492179
Age: embryonic day 10.5
Image: 3A HoxA13
Note: Authors report co-expression with Wnt5a in distal limb bud.
Detected: true
Specimen Num: 1
Publication
First Author: Shaut CA
Year: 2008
Journal: PLoS Genet
Title: HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification.
Volume: 4
Issue: 5
Pages: e1000073
Publication
First Author: Perez WD
Year: 2010
Journal: Dev Dyn
Title: Survival of Hoxa13 homozygous mutants reveals a novel role in digit patterning and appendicular skeletal development.
Volume: 239
Issue: 2
Pages: 446-57
Publication
First Author: Post LC
Year: 1999
Journal: Int J Dev Biol
Title: Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice.
Volume: 43
Issue: 4
Pages: 287-94
Publication
First Author: Shaut CA
Year: 2007
Journal: Dev Dyn
Title: HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.
Volume: 236
Issue: 4
Pages: 951-60
Publication
First Author: Knosp WM
Year: 2004
Journal: Development
Title: HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis.
Volume: 131
Issue: 18
Pages: 4581-92
Publication
First Author: Shou S
Year: 2013
Journal: Dev Dyn
Title: HOXA13 regulates Aldh1a2 expression in the autopod to facilitate interdigital programmed cell death.
Volume: 242
Issue: 6
Pages: 687-98
Publication
First Author: Stadler HS
Year: 2001
Journal: Development
Title: Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs.
Volume: 128
Issue: 21
Pages: 4177-88
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446488
Age: embryonic day 14.5
Image: 3 Hoxa13 14.5 wt
Note: Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3264522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446488
Age: embryonic day 14.5
Image: 3 Hoxa13 14.5 spdh/spdh
Note: Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes. Authors state that expression was stronger in mutant compared with wildtype.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5446453
Age: embryonic day 12.5
Image: 2 Hoxa13 12.5 wt
Note: Expression more restricted to perichondrial region of cartilaginous anlagen.
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5446453
Age: embryonic day 12.5
Image: 2 Hoxa13 12.5 spdh/spdh
Note: Reduced expression domain with normal anterior and posterior borders.
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3265822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446488
Age: embryonic day 14.5
Image: 3 Hoxa13 14.5 wt
Note: Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3265822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446488
Age: embryonic day 14.5
Image: 3 Hoxa13 14.5 spdh/spdh
Note: Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes. Authors state that expression was stronger in mutant compared with wildtype.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5446453
Age: embryonic day 11.5
Image: 2 Hoxa13 11.5 wt
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5446453
Age: embryonic day 11.5
Image: 2 Hoxa13 11.5 spdh/spdh
Note: Reduced expression domain with normal anterior and posterior borders.
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5446222
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1742922
Stage: TS22
Assay Id: MGI:5446488
Age: embryonic day 14.5
Image: 3 Hoxa13 14.5 wt
Detected: false
Specimen Num: 1
Allele
Name: homeobox A13; targeted mutation 1.1, Marie Kmita
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase, Reporter
Publication categories: ProxyCollection
Publication
First Author: Post LC
Year: 2000
Journal: Dev Biol
Title: Severe limb defects in Hypodactyly mice result from the expression of a novel, mutant HOXA13 protein.
Volume: 217
Issue: 2
Pages: 290-300
Allele
Name: homeobox A13; targeted mutation 1.1, Miguel Torres
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Hoxa13/Hoxa13<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Hoxa13/Hoxa13<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3 Hoxa13/Hoxa13<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3<+> Hoxa13/Hoxa13<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Salsi V
Year: 2006
Journal: J Biol Chem
Title: Hoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbs.
Volume: 281
Issue: 4
Pages: 1992-9
Genotype
Symbol: Gli3/Gli3 Hoxa13/Hoxa13<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxa13/Hoxa13<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Publication      
First Author: Karst SY
Year: 2009
Journal: MGI Direct Data Submission
Title: Hypodactyly like: a mutation causing fused and missing digits is likely an allele of the Hoxa13 gene
Protein
Organism: Mus musculus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus
Length: 219  
Fragment?: false
Protein
Organism: Mus musculus
Length: 218  
Fragment?: false
Publication
First Author: Williams TM
Year: 2005
Journal: Dev Biol
Title: Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.
Volume: 279
Issue: 2
Pages: 462-80
Publication
First Author: Rinn JL
Year: 2008
Journal: Genes Dev
Title: A dermal HOX transcriptional program regulates site-specific epidermal fate.
Volume: 22
Issue: 3
Pages: 303-7
Publication
First Author: Cobb J
Year: 2005
Journal: Development
Title: Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia.
Volume: 132
Issue: 13
Pages: 3055-67
Publication
First Author: Morgan EA
Year: 2003
Journal: Development
Title: Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia.
Volume: 130
Issue: 14
Pages: 3095-109
Publication
First Author: Warot X
Year: 1997
Journal: Development
Title: Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts.
Volume: 124
Issue: 23
Pages: 4781-91
Publication
First Author: Sheth R
Year: 2016
Journal: Cell Rep
Title: Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.
Volume: 17
Issue: 11
Pages: 2913-2926
Publication
First Author: Desanlis I
Year: 2020
Journal: Nat Commun
Title: HOX13-dependent chromatin accessibility underlies the transition towards the digit development program.
Volume: 11
Issue: 1
Pages: 2491
Publication
First Author: Fromental-Ramain C
Year: 1996
Journal: Development
Title: Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod.
Volume: 122
Issue: 10
Pages: 2997-3011
Publication
First Author: Bastida MF
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13.
Volume: 117
Issue: 2
Pages: 1090-1096
Publication
First Author: Mortlock DP
Year: 1996
Journal: Nat Genet
Title: The molecular basis of hypodactyly (Hd): a deletion in Hoxa 13 leads to arrest of digital arch formation.
Volume: 13
Issue: 3
Pages: 284-9
Publication
First Author: Zhang Y
Year: 2011
Journal: PLoS One
Title: Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Volume: 6
Issue: 8
Pages: e23069
Publication
First Author: Post LC
Year: 1999
Journal: Biol Reprod
Title: Infertility in adult hypodactyly mice is associated with hypoplasia of distal reproductive structures.
Volume: 61
Issue: 6
Pages: 1402-8
Publication
First Author: Robertson KE
Year: 1997
Journal: Int J Dev Biol
Title: Shh, Fgf4 and Hoxd gene expression in the mouse limb mutant hypodactyly.
Volume: 41
Issue: 5
Pages: 733-6
Publication
First Author: Innis JW
Year: 2004
Journal: Hum Mol Genet
Title: Polyalanine expansion in HOXA13: three new affected families and the molecular consequences in a mouse model.
Volume: 13
Issue: 22
Pages: 2841-51
Publication
First Author: Hamasaki Y
Year: 2012
Journal: Lab Invest
Title: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin ameliorates renal fibrosis through HOXA13-USAG-1 pathway.
Volume: 92
Issue: 8
Pages: 1161-70
Publication
First Author: Sheth R
Year: 2012
Journal: Science
Title: Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism.
Volume: 338
Issue: 6113
Pages: 1476-80
Publication
First Author: Migone FF
Year: 2012
Journal: Genesis
Title: Dominant activation of the hedgehog signaling pathway alters development of the female reproductive tract.
Volume: 50
Issue: 1
Pages: 28-40
Publication
First Author: Kmita M
Year: 2005
Journal: Nature
Title: Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.
Volume: 435
Issue: 7045
Pages: 1113-6
Publication
First Author: Bruneau S
Year: 2001
Journal: Dev Biol
Title: The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes.
Volume: 237
Issue: 2
Pages: 345-53
Publication
First Author: Lehoczky JA
Year: 2004
Journal: Evol Dev
Title: Conserved expression domains for genes upstream and within the HoxA and HoxD clusters suggests a long-range enhancer existed before cluster duplication.
Volume: 6
Issue: 6
Pages: 423-30
Publication
First Author: Lin C
Year: 2009
Journal: Development
Title: Temporal and spatial dissection of Shh signaling in genital tubercle development.
Volume: 136
Issue: 23
Pages: 3959-67
Publication
First Author: Williams TM
Year: 2005
Journal: Nucleic Acids Res
Title: Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.
Volume: 33
Issue: 14
Pages: 4475-84
Publication
First Author: Kawakami Y
Year: 2009
Journal: Development
Title: Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.
Volume: 136
Issue: 4
Pages: 585-94
Publication
First Author: Lu P
Year: 2008
Journal: Development
Title: The apical ectodermal ridge is a timer for generating distal limb progenitors.
Volume: 135
Issue: 8
Pages: 1395-405
Publication
First Author: Sheth R
Year: 2013
Journal: Development
Title: Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth.
Volume: 140
Issue: 10
Pages: 2130-8
Publication
First Author: Williams TM
Year: 2005
Journal: Dev Biol
Title: Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
Volume: 277
Issue: 2
Pages: 457-71
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hummel KP
Year: 1970
Journal: J Hered
Title: Hypodactyly, a semidominant lethal mutation in mice.
Volume: 61
Issue: 5
Pages: 219-20
Publication
First Author: Robertson KE
Year: 1996
Journal: Dev Genet
Title: Cellular analysis of limb development in the mouse mutant hypodactyly.
Volume: 19
Issue: 1
Pages: 9-25
Publication  
First Author: Hummel KP
Year: 1966
Journal: Mouse News Lett
Title: Hd - hypodactyly
Volume: 34
Pages: 31
Publication      
First Author: Moutier R
Year: 1976
Title: New mutations causing sterility restricted to the male in rats and mice
Pages: 115-7
Publication
First Author: Gibson DM
Year: 1979
Journal: J Exp Med
Title: Ef2: a new LY-3-linked light-chain marker expressed in normal mouse serum immunoglobulin.
Volume: 149
Issue: 6
Pages: 1477-86
Publication
First Author: D'Hoostelaere LA
Year: 1985
Journal: Immunogenetics
Title: Localization of CT beta and C kappa on mouse chromosome 6.
Volume: 22
Issue: 3
Pages: 277-83
Publication
First Author: Newman SA
Year: 1996
Journal: Bioessays
Title: Sticky fingers: Hox genes and cell adhesion in vertebrate limb development.
Volume: 18
Issue: 3
Pages: 171-4
GXD Expression    
Probe: MGI:1205614
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205616
Age: postnatal week 6-8
Image: st97_599
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1205614
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1205616
Age: postnatal week 6-8
Image: st97_599
Detected: false
Specimen Num: 14