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Search results 1 to 100 out of 3903 for Hprt

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Type Details Score
Strain
Attribute String: mutant stock
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Nesbitt MN
Year: 1979
Journal: Biochem Genet
Title: Isoenzyme pattern of HPRT in murine erythrocytes: control by an autosomal locus.
Volume: 17
Issue: 9-10
Pages: 957-64
Publication      
First Author: Korecki AJ
Year: 2019
Journal: Genetics
Title: Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele.
Publication
First Author: Portales-Casamar E
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A regulatory toolbox of MiniPromoters to drive selective expression in the brain.
Volume: 107
Issue: 38
Pages: 16589-94
Publication      
First Author: The Pleiades Promoter and CanEuCre Project
Year: 2014
Journal: MGI Direct Data Submission
Title: Generation of reporter and cre-expressing targeted transgenic mice in the Hprt1 gene using human MiniPromoters that drive region- and cell-specific gene expression in the mouse brain
Publication  
First Author: Day C
Year: 1977
Journal: Mouse News Lett
Title: HPRT mobility alteration, Hma.
Volume: 57
Pages: 10
Heritable Phenotypic Marker
Type: heritable_phenotypic_marker
Organism: Mus musculus
Publication    
First Author: Melton DW
Year: 1987
Title: HPRT gene organization and expression
Volume: 4
Pages: 34-76
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 320, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 345a, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 314, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 5, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 313, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Genotype
Symbol: Hprt/?
Background: B6.Cg-Hprt
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Moore TF
Year: 1992
Journal: Mouse Genome
Title: Failure to detect age-related reactivation at the Hprt locus
Volume: 90
Issue: 4
Pages: 687-89
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 318, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 328, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Allele
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 322, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Recombinase, Reporter
Publication categories: ProxyCollection
Publication
First Author: Kuehn MR
Year: 1987
Journal: Nature
Title: A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice.
Volume: 326
Issue: 6110
Pages: 295-8
Publication
First Author: Vogel M
Year: 2019
Journal: Stem Cells
Title: HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function.
Volume: 37
Issue: 12
Pages: 1606-1614
Publication
First Author: Thompson S
Year: 1989
Journal: Cell
Title: Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells.
Volume: 56
Issue: 2
Pages: 313-21
Publication
First Author: Bol SA
Year: 1998
Journal: Cancer Res
Title: Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.
Volume: 58
Issue: 13
Pages: 2850-6
Publication
First Author: Guillot PV
Year: 2000
Journal: Physiol Genomics
Title: Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression.
Volume: 2
Issue: 2
Pages: 77-83
Publication
First Author: Isamat M
Year: 1988
Journal: Somat Cell Mol Genet
Title: Characterization, evolutionary relationships, and chromosome location of processed mouse HPRT pseudogene.
Volume: 14
Issue: 4
Pages: 359-69
Publication
First Author: Heaney JD
Year: 2004
Journal: Genomics
Title: Tissue-specific expression of a BAC transgene targeted to the Hprt locus in mouse embryonic stem cells.
Volume: 83
Issue: 6
Pages: 1072-82
Publication
First Author: Evans V
Year: 2000
Journal: Physiol Genomics
Title: Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium.
Volume: 2
Issue: 2
Pages: 67-75
Publication
First Author: Palais G
Year: 2009
Journal: Physiol Genomics
Title: Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system.
Volume: 37
Issue: 2
Pages: 140-6
Publication
First Author: Lock LF
Year: 1986
Journal: Mol Cell Biol
Title: Methylation of the mouse hprt gene differs on the active and inactive X chromosomes.
Volume: 6
Issue: 3
Pages: 914-24
Publication
First Author: Pravtcheva DD
Year: 1994
Journal: J Exp Zool
Title: Mosaic expression of an Hprt transgene integrated in a region of Y heterochromatin.
Volume: 268
Issue: 6
Pages: 452-68
Publication
First Author: Tsuda H
Year: 1997
Journal: Genomics
Title: Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
Volume: 42
Issue: 3
Pages: 413-21
Publication
First Author: Masson W
Year: 1996
Journal: Mamm Genome
Title: The use of compound heterozygotes and Hprt selection to analyze X-linked mottled alleles associated with prenatal lethality.
Volume: 7
Issue: 7
Pages: 486-9
Publication
First Author: Guibinga GH
Year: 2013
Journal: Hum Mol Genet
Title: Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome.
Volume: 22
Issue: 22
Pages: 4502-15
Publication
First Author: Walker VE
Year: 1993
Journal: Mutat Res
Title: A mouse model for the study of in vivo mutational spectra: sequence specificity of ethylene oxide at the hprt locus.
Volume: 288
Issue: 1
Pages: 151-62
Publication
First Author: Cvetkovic B
Year: 2000
Journal: J Biol Chem
Title: Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination.
Volume: 275
Issue: 2
Pages: 1073-8
Publication
First Author: Sturm K
Year: 1999
Journal: Int J Dev Biol
Title: Pgk1 and Hprt gene activity in the peri-implantation mouse embryo is influenced by the parental origin of the X-chromosome.
Volume: 43
Issue: 1
Pages: 69-73
Publication
First Author: Vivian JL
Year: 1999
Journal: Biotechniques
Title: Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice.
Volume: 27
Issue: 1
Pages: 154-62
Publication
First Author: Kushi A
Year: 1998
Journal: Mamm Genome
Title: Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells--analysis of large deletion around hprt locus of ES cell.
Volume: 9
Issue: 4
Pages: 269-73
Publication
First Author: Magin TM
Year: 1992
Journal: Gene
Title: A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells.
Volume: 122
Issue: 2
Pages: 289-96
Publication
First Author: Lyon MF
Year: 1987
Journal: Cytogenet Cell Genet
Title: Localization of the Hprt locus by in situ hybridization and distribution of loci on the mouse X-chromosome.
Volume: 44
Issue: 2-3
Pages: 163-6
Publication
First Author: Dobrovolsky VN
Year: 1999
Journal: Environ Mol Mutagen
Title: Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes.
Volume: 34
Issue: 1
Pages: 30-8
Publication
First Author: Francke U
Year: 1979
Journal: Proc Natl Acad Sci U S A
Title: Assignment of the gene for cytoplasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse.
Volume: 76
Issue: 10
Pages: 5230-3
Publication
First Author: Ben-Zur T
Year: 1999
Journal: Genomics
Title: Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.
Volume: 58
Issue: 1
Pages: 102-3
Allele      
Name: HPRT mobility alteration; wild type
ProxyCollection
Publication
First Author: Wu CL
Year: 1993
Journal: Nat Genet
Title: Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.
Volume: 3
Issue: 3
Pages: 235-40
Publication
First Author: Jinnah HA
Year: 1992
Journal: Mol Cell Neurosci
Title: Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization.
Volume: 3
Issue: 1
Pages: 64-78
Publication
First Author: Cadieux C
Year: 2006
Journal: Cancer Res
Title: Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia.
Volume: 66
Issue: 19
Pages: 9492-501
Publication
First Author: Cadieux C
Year: 2009
Journal: Cancer Res
Title: Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types.
Volume: 69
Issue: 18
Pages: 7188-97
Publication
First Author: Okada Y
Year: 2008
Journal: Blood
Title: A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.
Volume: 112
Issue: 6
Pages: 2336-9
Publication
First Author: Minami T
Year: 2002
Journal: Blood
Title: Differential regulation of the von Willebrand factor and Flt-1 promoters in the endothelium of hypoxanthine phosphoribosyltransferase-targeted mice.
Volume: 100
Issue: 12
Pages: 4019-25
Publication
First Author: Liu J
Year: 2011
Journal: Blood
Title: Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.
Volume: 117
Issue: 1
Pages: 342-51
Publication
First Author: Ordway JM
Year: 1997
Journal: Cell
Title: Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
Volume: 91
Issue: 6
Pages: 753-63
Publication
First Author: Jinnah HA
Year: 1993
Journal: J Neurochem
Title: Brain purines in a genetic mouse model of Lesch-Nyhan disease.
Volume: 60
Issue: 6
Pages: 2036-45
Publication
First Author: Egami K
Year: 2007
Journal: Neurobiol Dis
Title: Basal ganglia dopamine loss due to defect in purine recycling.
Volume: 26
Issue: 2
Pages: 396-407
Publication  
First Author: Tschirner SK
Year: 2015
Journal: Neurosci Lett
Title: Altered histamine neurotransmission in HPRT-deficient mice.
Volume: 609
Pages: 74-80
Publication
First Author: Okada Y
Year: 2007
Journal: Circ Res
Title: A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.
Volume: 100
Issue: 12
Pages: 1712-22
Publication
First Author: Luchman HA
Year: 2008
Journal: Genesis
Title: Temporally controlled prostate epithelium-specific gene alterations.
Volume: 46
Issue: 4
Pages: 229-34
Publication
First Author: Ryu KY
Year: 2007
Journal: EMBO J
Title: The mouse polyubiquitin gene UbC is essential for fetal liver development, cell-cycle progression and stress tolerance.
Volume: 26
Issue: 11
Pages: 2693-706
Publication
First Author: Gu JJ
Year: 2000
Journal: J Clin Invest
Title: Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene.
Volume: 106
Issue: 4
Pages: 599-606
Publication
First Author: Gu JJ
Year: 2003
Journal: Mol Cell Biol
Title: Targeted disruption of the inosine 5'-monophosphate dehydrogenase type I gene in mice.
Volume: 23
Issue: 18
Pages: 6702-12
Publication
First Author: Jinnah HA
Year: 1999
Journal: J Neurochem
Title: Influence of age and strain on striatal dopamine loss in a genetic mouse model of Lesch-Nyhan disease.
Volume: 72
Issue: 1
Pages: 225-9
Publication
First Author: Hooper M
Year: 1987
Journal: Nature
Title: HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells.
Volume: 326
Issue: 6110
Pages: 292-5
Publication
First Author: Keebaugh AC
Year: 2011
Journal: PLoS One
Title: PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse.
Volume: 6
Issue: 7
Pages: e22381
Publication
First Author: Mikolaenko I
Year: 2005
Journal: Neurobiol Dis
Title: A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease.
Volume: 20
Issue: 2
Pages: 479-90
Publication
First Author: Guibinga GH
Year: 2014
Journal: PLoS One
Title: Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome.
Volume: 9
Issue: 5
Pages: e96575
Publication
First Author: Hacke K
Year: 2012
Journal: Exp Hematol
Title: Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow.
Volume: 40
Issue: 1
Pages: 3-13.e3
Publication
First Author: Moore TF
Year: 1992
Journal: Development
Title: Imprinting of phosphoribosyltransferases during preimplantation development of the mouse mutant, Hprtb-m3.
Volume: 115
Issue: 4
Pages: 1011-6
Publication  
First Author: de Leeuw CN
Year: 2014
Journal: Mol Ther Methods Clin Dev
Title: Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.
Volume: 1
Pages: 5
Publication
First Author: Birch J
Year: 2016
Journal: Biol Open
Title: The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma.
Volume: 5
Issue: 10
Pages: 1371-1379
Publication
First Author: Clarke CJ
Year: 2016
Journal: Curr Biol
Title: The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis.
Volume: 26
Issue: 6
Pages: 755-65
Publication
First Author: Yang C
Year: 2012
Journal: Genetics
Title: Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing.
Volume: 192
Issue: 4
Pages: 1281-93
Publication
First Author: Jinnah HA
Year: 1994
Journal: J Neurosci
Title: Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 14
Issue: 3 Pt 1
Pages: 1164-75
Publication
First Author: Zennaro C
Year: 2017
Journal: PLoS One
Title: The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Volume: 12
Issue: 3
Pages: e0173512
Publication
First Author: Jinnah HA
Year: 1992
Journal: J Pharmacol Exp Ther
Title: Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome.
Volume: 263
Issue: 2
Pages: 596-607
Publication
First Author: Asahi M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
Volume: 101
Issue: 25
Pages: 9199-204
Publication  
First Author: Schmouth JF
Year: 2013
Journal: BMC Biol
Title: Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.
Volume: 11
Pages: 106
Publication
First Author: Gramolini AO
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation.
Volume: 103
Issue: 7
Pages: 2446-51
Publication
First Author: Zaslavsky A
Year: 2013
Journal: Blood
Title: The calcineurin-NFAT pathway negatively regulates megakaryopoiesis.
Volume: 121
Issue: 16
Pages: 3205-15
Publication
First Author: Zhang SY
Year: 2010
Journal: Sci Signal
Title: c-mip impairs podocyte proximal signaling and induces heavy proteinuria.
Volume: 3
Issue: 122
Pages: ra39
Publication
First Author: Dart DA
Year: 2013
Journal: PLoS One
Title: Visualising androgen receptor activity in male and female mice.
Volume: 8
Issue: 8
Pages: e71694
Publication
First Author: Chapman VM
Year: 1983
Journal: Genetics
Title: Electrophoretic variation for X chromosome-linked hypoxanthine phosphoribosyl transferase (HPRT) in wild-derived mice.
Volume: 103
Issue: 4
Pages: 785-95
Publication
First Author: Bronson SK
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Single-copy transgenic mice with chosen-site integration.
Volume: 93
Issue: 17
Pages: 9067-72
Publication
First Author: Ramdzan ZM
Year: 2014
Journal: PLoS Biol
Title: RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
Volume: 12
Issue: 3
Pages: e1001807
Publication
First Author: Magness ST
Year: 2004
Journal: J Immunol
Title: In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse.
Volume: 173
Issue: 3
Pages: 1561-70
Publication
First Author: Pratt MA
Year: 2009
Journal: Oncogene
Title: The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population.
Volume: 28
Issue: 30
Pages: 2710-22
Publication
First Author: Miller JA
Year: 2011
Journal: J Neurosci Res
Title: Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons.
Volume: 89
Issue: 3
Pages: 406-17
Publication
First Author: Ding S
Year: 2010
Journal: PLoS One
Title: High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse.
Volume: 5
Issue: 8
Pages: e12191
Publication
First Author: De Miranda BR
Year: 2015
Journal: Toxicol Sci
Title: Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.
Volume: 143
Issue: 2
Pages: 360-73
Publication
First Author: Belkina AC
Year: 2013
Journal: J Immunol
Title: BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.
Volume: 190
Issue: 7
Pages: 3670-8
Publication
First Author: Tang SH
Year: 2002
Journal: Genesis
Title: A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.
Volume: 32
Issue: 3
Pages: 199-202
Publication
First Author: Plumb TJ
Year: 1996
Journal: Neurosci Lett
Title: Hypoxanthine-guanine phosphoribosyltransferase (HPRT) expression in the central nervous system of HPRT-deficient mice following adenoviral-mediated gene transfer.
Volume: 214
Issue: 2-3
Pages: 159-62
Publication
First Author: Brennand J
Year: 1982
Journal: Proc Natl Acad Sci U S A
Title: Cloned cDNA sequences of the hypoxanthine/guanine phosphoribosyltransferase gene from a mouse neuroblastoma cell line found to have amplified genomic sequences.
Volume: 79
Issue: 6
Pages: 1950-4
Publication
First Author: Gautier EL
Year: 2009
Journal: Circulation
Title: Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage.
Volume: 119
Issue: 13
Pages: 1795-804
Publication
First Author: Cogliati S
Year: 2013
Journal: Cell
Title: Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency.
Volume: 155
Issue: 1
Pages: 160-71
Publication
First Author: Quintana-Cabrera R
Year: 2018
Journal: Nat Commun
Title: The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function.
Volume: 9
Issue: 1
Pages: 3399
Publication
First Author: Yang GS
Year: 2009
Journal: Genomics
Title: Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.
Volume: 93
Issue: 3
Pages: 196-204
Publication
First Author: Selmi-Ruby S
Year: 2014
Journal: Endocrinology
Title: The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.
Volume: 155
Issue: 2
Pages: 635-46
Publication
First Author: Luchman HA
Year: 2008
Journal: PLoS One
Title: The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.
Volume: 3
Issue: 12
Pages: e3940