Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Strain |
Attribute String: |
strain family |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Russell LB |
Year: |
1957 |
Journal: |
Mouse News Lett |
Title: |
HR - tw legs |
Volume: |
17 |
|
Pages: |
84 |
|
•
•
•
•
•
|
Publication |
First Author: |
DERINGER MK |
Year: |
1956 |
Journal: |
J Natl Cancer Inst |
Title: |
The effect of subcutaneous inoculation of 4-o-tolylazo-o-toluidine in strain HR mice. |
Volume: |
17 |
Issue: |
4 |
Pages: |
533-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Green MC |
Year: |
1971 |
Journal: |
Mouse News Lett |
Title: |
Linkage: Rn, hr and s in Chr 14 |
Volume: |
44 |
|
Pages: |
30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
A novel nonsense mutation in mouse hr locus |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu K |
Year: |
2017 |
Journal: |
Exp Anim |
Title: |
Transgenic mice display hair loss and regrowth overexpressing mutant Hr gene. |
Volume: |
66 |
Issue: |
4 |
Pages: |
379-386 |
|
•
•
•
•
•
|
Ontology Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Connor MJ |
Year: |
1994 |
Journal: |
Arch Toxicol |
Title: |
The hr locus and the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in newborn mice. |
Volume: |
69 |
Issue: |
2 |
Pages: |
87-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JK |
Year: |
2010 |
Journal: |
Hum Mol Genet |
Title: |
Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis. |
Volume: |
19 |
Issue: |
3 |
Pages: |
445-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
DERINGER MK |
Year: |
1951 |
Journal: |
J Natl Cancer Inst |
Title: |
Spontaneous and induced tumors in haired and hairless strain HR mice. |
Volume: |
12 |
Issue: |
2 |
Pages: |
437-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi JH |
Year: |
2011 |
Journal: |
BMB Rep |
Title: |
Downregulation of Foxe1 by HR suppresses Msx1 expression in the hair follicles of Hr(Hp) mice. |
Volume: |
44 |
Issue: |
7 |
Pages: |
478-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nam Y |
Year: |
2006 |
Journal: |
Genomics |
Title: |
A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu. |
Volume: |
87 |
Issue: |
4 |
Pages: |
520-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brancaz-Bouvier MV |
Year: |
2008 |
Journal: |
J Invest Dermatol |
Title: |
The "bald Mill Hill" mutation in the mouse is associated with an abnormal, mislocalized HR bmh protein. |
Volume: |
128 |
Issue: |
2 |
Pages: |
311-21 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1181
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Herschman HR |
Year: |
1996 |
Journal: |
Biochim Biophys Acta |
Title: |
Prostaglandin synthase 2. |
Volume: |
1299 |
Issue: |
1 |
Pages: |
125-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baek IC |
Year: |
2009 |
Journal: |
Mamm Genome |
Title: |
A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis. |
Volume: |
20 |
Issue: |
6 |
Pages: |
350-8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6190564 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Hr |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6190564 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Hr |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190564 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Hr |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190564 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Hr |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190564 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Hr |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190564 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Hr |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6175057 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190564 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Hr |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones JM |
Year: |
1993 |
Journal: |
Mamm Genome |
Title: |
Insertional mutation of the hairless locus on mouse chromosome 14. |
Volume: |
4 |
Issue: |
11 |
Pages: |
639-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim H |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling. |
Volume: |
7 |
Issue: |
6 |
Pages: |
e39691 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panteleyev AA |
Year: |
1998 |
Journal: |
J Invest Dermatol |
Title: |
Towards defining the pathogenesis of the hairless phenotype. |
Volume: |
110 |
Issue: |
6 |
Pages: |
902-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cachón-González MB |
Year: |
1999 |
Journal: |
Dev Dyn |
Title: |
The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype. |
Volume: |
216 |
Issue: |
2 |
Pages: |
113-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panteleyev AA |
Year: |
1999 |
Journal: |
Am J Pathol |
Title: |
The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation. |
Volume: |
155 |
Issue: |
1 |
Pages: |
159-71 |
|
•
•
•
•
•
|
Allele |
Name: |
lysine demethylase and nuclear receptor corepressor; hairless |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stelzner KF |
Year: |
1983 |
Journal: |
J Hered |
Title: |
Four dominant autosomal mutations affecting skin and hair development in the mouse. |
Volume: |
74 |
Issue: |
3 |
Pages: |
193-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cachon-Gonzalez MB |
Year: |
1994 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structure and expression of the hairless gene of mice. |
Volume: |
91 |
Issue: |
16 |
Pages: |
7717-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brooke HC |
Year: |
1926 |
Journal: |
J Hered |
Title: |
Hairless mice. |
Volume: |
17 |
Issue: |
5 |
Pages: |
173-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jain AK |
Year: |
2015 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin. |
Volume: |
285 |
Issue: |
1 |
Pages: |
71-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura Y |
Year: |
2009 |
Journal: |
J Nutr |
Title: |
Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. |
Volume: |
139 |
Issue: |
11 |
Pages: |
2079-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hiai H |
Year: |
1977 |
Journal: |
Nature |
Title: |
Selective expression of xenotropic virus in congenic HRS/J (hairless) mice. |
Volume: |
270 |
Issue: |
5634 |
Pages: |
247-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meier H |
Year: |
1969 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Genetic control by the hr-locus of susceptibility and resistance to leukemia. |
Volume: |
63 |
Issue: |
3 |
Pages: |
759-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vollmar B |
Year: |
2000 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Skin microvascular adaptations during maturation and aging of hairless mice. |
Volume: |
279 |
Issue: |
4 |
Pages: |
H1591-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalin JH |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model. |
Volume: |
14 |
Issue: |
3 |
Pages: |
e0213095 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gallagher CH |
Year: |
1984 |
Journal: |
J Invest Dermatol |
Title: |
Characterization and histogenesis of tumors in the hairless mouse produced by low-dosage incremental ultraviolet radiation. |
Volume: |
83 |
Issue: |
3 |
Pages: |
169-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Astner S |
Year: |
2007 |
Journal: |
Skin Pharmacol Physiol |
Title: |
Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice. |
Volume: |
20 |
Issue: |
6 |
Pages: |
283-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
MONTAGNA W |
Year: |
1952 |
Journal: |
J Invest Dermatol |
Title: |
The skin of hairless mice. I. The formation of cysts and the distribution of lipids. |
Volume: |
19 |
Issue: |
1 |
Pages: |
83-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson DA |
Year: |
1981 |
Journal: |
J Immunol |
Title: |
Immune responsiveness of HRS/J mice to syngeneic lymphoma cells. |
Volume: |
127 |
Issue: |
2 |
Pages: |
461-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang YC |
Year: |
2014 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. |
Volume: |
280 |
Issue: |
2 |
Pages: |
236-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heiniger HJ |
Year: |
1976 |
Journal: |
J Natl Cancer Inst |
Title: |
Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis. |
Volume: |
56 |
Issue: |
5 |
Pages: |
1073-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dunn TB |
Year: |
1968 |
Journal: |
J Natl Cancer Inst |
Title: |
Reticulum cell neoplasm, type B, or the "Hodgkin's-like lesion" of the mouse. |
Volume: |
40 |
Issue: |
4 |
Pages: |
771-821 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mucenski ML |
Year: |
1988 |
Journal: |
J Virol |
Title: |
Comparative molecular genetic analysis of lymphomas from six inbred mouse strains. |
Volume: |
62 |
Issue: |
3 |
Pages: |
839-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato J |
Year: |
2000 |
Journal: |
Arch Dermatol Res |
Title: |
Water content and thickness of the stratum corneum contribute to skin surface morphology. |
Volume: |
292 |
Issue: |
8 |
Pages: |
412-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pratheeshkumar P |
Year: |
2014 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin. |
Volume: |
280 |
Issue: |
1 |
Pages: |
127-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tober KL |
Year: |
2007 |
Journal: |
J Invest Dermatol |
Title: |
Effects of UVB on E prostanoid receptor expression in murine skin. |
Volume: |
127 |
Issue: |
1 |
Pages: |
214-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Batal M |
Year: |
2014 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
DNA damage in internal organs after cutaneous exposure to sulphur mustard. |
Volume: |
278 |
Issue: |
1 |
Pages: |
39-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodriguez-Martin M |
Year: |
2011 |
Journal: |
J Invest Dermatol |
Title: |
Expression of epidermal CAMP changes in parallel with permeability barrier status. |
Volume: |
131 |
Issue: |
11 |
Pages: |
2263-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heston WE |
Year: |
1963 |
|
Title: |
Genetics of Neoplasia |
|
|
Pages: |
247-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Konger RL |
Year: |
2016 |
Journal: |
Exp Dermatol |
Title: |
Comparison of the acute ultraviolet photoresponse in congenic albino hairless C57BL/6J mice relative to outbred SKH1 hairless mice. |
Volume: |
25 |
Issue: |
9 |
Pages: |
688-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Schanke A |
Year: |
2005 |
Journal: |
J Invest Dermatol |
Title: |
Single UVB overexposure stimulates melanocyte proliferation in murine skin, in contrast to fractionated or UVA-1 exposure. |
Volume: |
124 |
Issue: |
1 |
Pages: |
241-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong SK |
Year: |
2008 |
Journal: |
J Invest Dermatol |
Title: |
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery. |
Volume: |
128 |
Issue: |
8 |
Pages: |
1930-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilgus TA |
Year: |
2003 |
Journal: |
Mol Carcinog |
Title: |
Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer. |
Volume: |
38 |
Issue: |
1 |
Pages: |
33-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heiniger HJ |
Year: |
1974 |
Journal: |
Cancer Res |
Title: |
Hereditary immunodeficiency and leukemogenesis in HRS-J mice. |
Volume: |
34 |
Issue: |
1 |
Pages: |
201-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pottathil R |
Year: |
1978 |
Journal: |
Naturwissenschaften |
Title: |
Suppression of leukemogenesis in hairless mice by anti-type C viral immune gamma globulins. |
Volume: |
65 |
Issue: |
8 |
Pages: |
443-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Batal M |
Year: |
2013 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Temporal and spatial features of the formation of DNA adducts in sulfur mustard-exposed skin. |
Volume: |
273 |
Issue: |
3 |
Pages: |
644-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
D'Agostini F |
Year: |
2001 |
Journal: |
Int J Oncol |
Title: |
Pilot studies evaluating the lung tumor yield in cigarette smoke-exposed mice. |
Volume: |
18 |
Issue: |
3 |
Pages: |
607-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu YP |
Year: |
1999 |
Journal: |
Cancer Res |
Title: |
Time course for early adaptive responses to ultraviolet B light in the epidermis of SKH-1 mice. |
Volume: |
59 |
Issue: |
18 |
Pages: |
4591-602 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reske-Kunz AB |
Year: |
1979 |
Journal: |
J Exp Med |
Title: |
Disproportion in T-cell subpopulations in immunodeficient mutant hr/hr mice. |
Volume: |
149 |
Issue: |
1 |
Pages: |
228-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin Y |
Year: |
2013 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Quercitrin protects skin from UVB-induced oxidative damage. |
Volume: |
269 |
Issue: |
2 |
Pages: |
89-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morrissey PJ |
Year: |
1980 |
Journal: |
J Immunol |
Title: |
Immunologic abnormalities in HRS/J mice. I. Specific deficit in T lymphocyte helper function in a mutant mouse. |
Volume: |
125 |
Issue: |
4 |
Pages: |
1558-62 |
|
•
•
•
•
•
|
Publication |
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