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Search results 1 to 100 out of 851 for Hras

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
key_1584440 | Hras
Type: gene
Organism: Not Specified
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Gene
127486605 | Hras
Type: gene
Organism: rabbit, European
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Gene
3265 | HRAS
Type: gene
Organism: human
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Gene
293621 | Hras
Type: gene
Organism: rat
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Gene
403735 | HRAS
Type: gene
Organism: dog, domestic
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Gene
466302 | HRAS
Type: gene
Organism: chimpanzee
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Gene
100298939 | HRAS
Type: gene
Organism: cattle
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Gene
396229 | HRAS
Type: gene
Organism: chicken
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Gene
698830 | HRAS
Type: gene
Organism: macaque, rhesus
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Gene
549757 | hras
Type: gene
Organism: frog, western clawed
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Gene
key_36139 | HRAS
Type: gene
Organism: cat, domestic
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Protein Coding Gene
MGI:96224 | Hras
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36330334 | J:331069
 
First Author: Nandi S
Year: 2022
Journal: Front Cell Dev Biol
Title: Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.
Volume: 10
Pages: 1000575
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Publication
31873167 | J:297818
First Author: Park JC
Year: 2019
Journal: Sci Rep
Title: WDR76 mediates obesity and hepatic steatosis via HRas destabilization.
Volume: 9
Issue: 1
Pages: 19676
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Publication
12589428 | J:83205
First Author: Goldberg M
Year: 2003
Journal: Hum Genet
Title: Biallelic expression of HRAS and MUCDHL in human and mouse.
Volume: 112
Issue: 4
Pages: 334-42
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Publication
8922043 | J:36374
First Author: Przybojewska B
Year: 1996
Journal: Acta Biochim Pol
Title: Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.
Volume: 43
Issue: 3
Pages: 575-8
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Publication
7526162 | J:29989
First Author: Moulds BA
Year: 1994
Journal: Mutat Res
Title: Spontaneous mutation at codon 61 of the Ha-ras gene in the nascent liver of B6C3F1, C3H/He and C57BL/6 mice.
Volume: 311
Issue: 1
Pages: 1-7
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Publication
26203562 | J:226044
   
First Author: Riemondy K
Year: 2015
Journal: Elife
Title: MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Volume: 4
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Publication
25795707 | J:221118
First Author: He F
Year: 2015
Journal: Cancer Res
Title: Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas.
Volume: 75
Issue: 10
Pages: 2017-28
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Publication
35230976 | J:325021
 
First Author: Dard L
Year: 2022
Journal: J Clin Invest
Title: HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models.
Volume: 132
Issue: 8
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Publication
27185863 | J:246653
First Author: Park JC
Year: 2016
Journal: J Cell Sci
Title: Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development.
Volume: 129
Issue: 15
Pages: 2997-3007
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Publication
29254681 | J:259739
 
First Author: Oba D
Year: 2018
Journal: EBioMedicine
Title: Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Volume: 27
Pages: 138-150
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Publication
34553752 | J:314851
 
First Author: Tidyman WE
Year: 2022
Journal: Dis Model Mech
Title: MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model.
Volume: 15
Issue: 2
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Publication
12941805 | J:85134
First Author: Nagase H
Year: 2003
Journal: Cancer Res
Title: Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.
Volume: 63
Issue: 16
Pages: 4849-53
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Publication
26452271 | J:243686
First Author: Weyandt JD
Year: 2015
Journal: PLoS One
Title: Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.
Volume: 10
Issue: 10
Pages: e0140253
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Publication
31685810 | J:293435
First Author: Fuentes-Mateos R
Year: 2019
Journal: Cell Death Dis
Title: Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice.
Volume: 10
Issue: 11
Pages: 838
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Publication
28455524 | J:274550
First Author: Schreiber J
Year: 2017
Journal: Sci Rep
Title: Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models.
Volume: 7
Issue: 1
Pages: 1256
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UniProt Feature
UniProt Feature
Begin: 1
Description: GTPase HRas
Type: chain
End: 186
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Publication
10869344 | J:64313
First Author: Shao H
Year: 2000
Journal: J Biol Chem
Title: A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras.
Volume: 275
Issue: 35
Pages: 26914-24
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Publication
27872088 | J:239406
First Author: Drosten M
Year: 2017
Journal: Cancer Res
Title: H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences.
Volume: 77
Issue: 3
Pages: 707-718
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HT Experiment
E-GEOD-60769 | Normal mouse skin lacking Hras
Series Id: GSE60769
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
18823404 | J:151146
First Author: Viosca J
Year: 2009
Journal: Genes Brain Behav
Title: Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome.
Volume: 8
Issue: 1
Pages: 60-71
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Publication
20926682 | J:182933
First Author: Sauzeau V
Year: 2010
Journal: Mol Biol Cell
Title: Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters.
Volume: 21
Issue: 23
Pages: 4251-63
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Publication
26190969 | J:323486
 
First Author: Wang T
Year: 2015
Journal: Front Cell Neurosci
Title: In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.
Volume: 9
Pages: 234
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Gene
424903 | HRASLS
Type: gene
Organism: chicken
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Gene
550286 | hrasa
Type: gene
Organism: zebrafish
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Gene
553656 | hrasb
Type: gene
Organism: zebrafish
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Publication
18483625 | J:137729
First Author: Schuhmacher AJ
Year: 2008
Journal: J Clin Invest
Title: A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Volume: 118
Issue: 6
Pages: 2169-79
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Publication
2543942 | J:68423
First Author: Sandgren EP
Year: 1989
Journal: Oncogene
Title: Oncogene-induced liver neoplasia in transgenic mice.
Volume: 4
Issue: 6
Pages: 715-24
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Publication
36943390 | J:348888
 
First Author: Ovejero D
Year: 2023
Journal: J Clin Invest
Title: Murine models of HRAS-mediated cutaneous skeletal hypophosphatemia syndrome suggest bone as the FGF23 excess source.
Volume: 133
Issue: 9
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Publication
22576369 | J:241280
 
First Author: Sala V
Year: 2012
Journal: Mol Med
Title: Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.
Volume: 18
Pages: 938-47
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Publication
11695564 | J:73016
 
First Author: Tamaoki N
Year: 2001
Journal: Toxicol Pathol
Title: The rasH2 transgenic mouse: nature of the model and mechanistic studies on tumorigenesis.
Volume: 29 Suppl
Pages: 81-9
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Publication
11326421 | J:68047
First Author: Ohnishi Y
Year: 2001
Journal: Exp Anim
Title: Induction of drug metabolism-related enzymes by methylcholanthrene and phenobarbital in transgenic mice carrying human prototype c-Ha-ras gene and their wild type littermates.
Volume: 50
Issue: 1
Pages: 33-9
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Publication
10814892 | J:62430
First Author: Katsutani N
Year: 2000
Journal: Toxicol Lett
Title: Hepatic drug metabolizing enzymes induced by clofibrate in rasH2 mice.
Volume: 115
Issue: 3
Pages: 223-9
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Publication
11370830 | J:69742
First Author: Ohno K
Year: 2001
Journal: J Exp Clin Cancer Res
Title: Effect of bacterial metabolism in the intestine on colorectal tumors induced by 1,2-dimethylhydrazine in transgenic mice harboring human prototype c-Ha-ras genes.
Volume: 20
Issue: 1
Pages: 51-6
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Publication
19416908 | J:148393
First Author: Chen X
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.
Volume: 106
Issue: 19
Pages: 7979-84
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Publication
32516567 | J:306078
First Author: Cai EY
Year: 2020
Journal: Cell Stem Cell
Title: Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Volume: 27
Issue: 2
Pages: 270-283.e7
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Publication
30655611 | J:270596
First Author: Jeong WJ
Year: 2019
Journal: Nat Commun
Title: WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.
Volume: 10
Issue: 1
Pages: 295
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Publication
3022995 | J:8473
First Author: Stallings RL
Year: 1986
Journal: Cytogenet Cell Genet
Title: Assignment of RAS proto-oncogenes in Chinese hamsters: implications for mammalian gene linkage conservation and neoplasia.
Volume: 43
Issue: 1-2
Pages: 2-5
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Publication
15902970 | J:98988
First Author: Ozaki M
Year: 2005
Journal: Toxicol Pathol
Title: Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains.
Volume: 33
Issue: 2
Pages: 267-71
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Publication
17256055 | J:118042
First Author: Mo L
Year: 2007
Journal: J Clin Invest
Title: Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis.
Volume: 117
Issue: 2
Pages: 314-25
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Publication
24057668 | J:204891
First Author: Goodwin AF
Year: 2014
Journal: Hum Mol Genet
Title: Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation.
Volume: 23
Issue: 3
Pages: 682-92
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Publication
36287323 | J:350527
First Author: Qu W
Year: 2023
Journal: Mol Neurobiol
Title: Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer's Mice.
Volume: 60
Issue: 2
Pages: 495-511
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Publication
32792500 | J:308382
First Author: Katata Y
Year: 2020
Journal: Cell Death Dis
Title: Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-induced atopic dermatitis.
Volume: 11
Issue: 8
Pages: 617
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Publication
25947161 | J:234077
First Author: Krencik R
Year: 2015
Journal: Sci Transl Med
Title: Dysregulation of astrocyte extracellular signaling in Costello syndrome.
Volume: 7
Issue: 286
Pages: 286ra66
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Publication
24240680 | J:216269
First Author: Chen X
Year: 2014
Journal: Oncogene
Title: Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
Volume: 33
Issue: 47
Pages: 5442-9
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Publication
37075955 | J:345102
 
First Author: Zhu J
Year: 2023
Journal: Behav Brain Res
Title: The 2210408F21Rik/miR-1968-5p/Hras axis regulates synapse-related proteins in a mouse model of depressive-like behaviors through a ceRNA mechanism.
Volume: 447
Pages: 114440
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Publication
28117393 | J:320537
 
First Author: Newlaczyl AU
Year: 2017
Journal: Sci Rep
Title: Quantification of spatiotemporal patterns of Ras isoform expression during development.
Volume: 7
Pages: 41297
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Publication
15870287 | J:99136
First Author: Bardeesy N
Year: 2005
Journal: Mol Cell Biol
Title: Role of epidermal growth factor receptor signaling in RAS-driven melanoma.
Volume: 25
Issue: 10
Pages: 4176-88
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Publication
28856719 | J:253098
First Author: Titus HE
Year: 2017
Journal: Glia
Title: Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling.
Volume: 65
Issue: 12
Pages: 1990-2002
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Publication
31050682 | J:353640
First Author: Yamada M
Year: 2019
Journal: PLoS Genet
Title: Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras.
Volume: 15
Issue: 5
Pages: e1008139
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Publication
24213576 | J:216271
First Author: Zhu B
Year: 2014
Journal: Oncogene
Title: PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling.
Volume: 33
Issue: 46
Pages: 5348-59
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Protein
Q61411
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q61411-2
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
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Protein
A0A1B0GRN0
Organism: Mus musculus/domesticus
Length: 19  
Fragment?: true
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Gene
367858 | Hrasl1
Type: gene
Organism: rat
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Publication
18059342 | J:135610
First Author: Nakamura K
Year: 2008
Journal: Oncogene
Title: Partial functional overlap of the three ras genes in mouse embryonic development.
Volume: 27
Issue: 21
Pages: 2961-8
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Publication
29760048 | J:264284
First Author: Untch BR
Year: 2018
Journal: Cancer Res
Title: Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.
Volume: 78
Issue: 16
Pages: 4642-4657
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Publication
27911940 | J:250854
First Author: Weyandt JD
Year: 2016
Journal: PLoS One
Title: Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Volume: 11
Issue: 12
Pages: e0167205
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Publication
27207659 | J:233956
First Author: Keller RR
Year: 2016
Journal: Carcinogenesis
Title: Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.
Volume: 37
Issue: 8
Pages: 810-816
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Publication
15314658 | J:93298
First Author: Kelly-Spratt KS
Year: 2004
Journal: PLoS Biol
Title: p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
Volume: 2
Issue: 8
Pages: E242
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Publication
23918800 | J:205014
First Author: Elangovan S
Year: 2013
Journal: Mol Cell Biol
Title: Molecular mechanism of SLC5A8 inactivation in breast cancer.
Volume: 33
Issue: 19
Pages: 3920-35
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Publication
26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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Publication
22945650 | J:203248
First Author: To MD
Year: 2013
Journal: Oncogene
Title: Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Volume: 32
Issue: 34
Pages: 4028-33
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Publication
28481866 | J:247825
First Author: Xin B
Year: 2017
Journal: Oncogene
Title: Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways.
Volume: 36
Issue: 36
Pages: 5087-5097
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Publication
30670749 | J:275239
First Author: Yee CH
Year: 2019
Journal: Sci Rep
Title: Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS.
Volume: 9
Issue: 1
Pages: 270
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Publication
20179099 | J:159024
First Author: Ichise T
Year: 2010
Journal: Development
Title: H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice.
Volume: 137
Issue: 6
Pages: 1003-13
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Protein Coding Gene
MGP_CAROLIEiJ_G0030681 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033214 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032241 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032988 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033130 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031945 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013880 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031792 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8417808 | J:3657
First Author: Gariboldi M
Year: 1993
Journal: Cancer Res
Title: Chromosome mapping of murine susceptibility loci to liver carcinogenesis.
Volume: 53
Issue: 2
Pages: 209-11
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Publication
20032959 | J:184278
First Author: Grande MT
Year: 2010
Journal: Kidney Int
Title: Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice.
Volume: 77
Issue: 6
Pages: 509-18
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Publication
22094331 | J:180602
First Author: Fuentes-Calvo I
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: H-Ras isoform modulates extracellular matrix synthesis, proliferation, and migration in fibroblasts.
Volume: 302
Issue: 4
Pages: C686-97
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Publication
10729330 | J:120544
First Author: Manabe T
Year: 2000
Journal: J Neurosci
Title: Regulation of long-term potentiation by H-Ras through NMDA receptor phosphorylation.
Volume: 20
Issue: 7
Pages: 2504-11
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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