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Search results 1 to 100 out of 307 for Hsd11b1

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Type Details Score
Gene
3290 | HSD11B1
Type: gene
Organism: human
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Gene
457698 | HSD11B1
Type: gene
Organism: chimpanzee
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Gene
282589 | HSD11B1
Type: gene
Organism: cattle
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Gene
574322 | HSD11B1
Type: gene
Organism: macaque, rhesus
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Gene
100489345 | hsd11b1
Type: gene
Organism: frog, western clawed
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Gene
25116 | Hsd11b1
Type: gene
Organism: rat
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Gene
449023 | HSD11B1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:103562 | Hsd11b1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
101930114 | HSD11B1-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
   
Probe: MGI:5296873
Assay Type: RT-PCR
Annotation Date: 2011-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5296892
Age: embryonic day 7.5
Image: 1
Specimen Label: Hsd11b1 +
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5296873
Assay Type: RT-PCR
Annotation Date: 2011-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5296892
Age: embryonic day 7.5
Image: 1
Specimen Label: Hsd11b1 -
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190567
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Hsd11b1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190567
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Hsd11b1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190567
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Hsd11b1
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190567
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Hsd11b1
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190567
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Hsd11b1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190567
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Hsd11b1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6175080
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190567
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Hsd11b1
Detected: true
Specimen Num: 7
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Publication
11739957 | J:107046
First Author: Masuzaki H
Year: 2001
Journal: Science
Title: A transgenic model of visceral obesity and the metabolic syndrome.
Volume: 294
Issue: 5549
Pages: 2166-70
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Publication
27566776 | J:235661
First Author: Zeng X
Year: 2016
Journal: Genes Dev
Title: Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.
Volume: 30
Issue: 16
Pages: 1822-36
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Publication
28676523 | J:271961
First Author: Zhang Z
Year: 2017
Journal: J Endocrinol
Title: Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis.
Volume: 234
Issue: 3
Pages: 291-299
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Publication
20045394 | J:157082
First Author: Huang Y
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Regulation of 11beta-hydroxysteroid dehydrogenase 1 and 2 by IGF-1 in mice.
Volume: 391
Issue: 4
Pages: 1752-6
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Publication
26465199 | J:232825
First Author: White CI
Year: 2016
Journal: Endocrinology
Title: Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice.
Volume: 157
Issue: 1
Pages: 346-57
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Publication
36246869 | J:330886
 
First Author: Akalestou E
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice.
Volume: 13
Pages: 1020576
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Publication
28749080 | J:265005
First Author: Zielinska AE
Year: 2017
Journal: Cell Biochem Funct
Title: Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle.
Volume: 35
Issue: 5
Pages: 269-277
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Protein Coding Gene
MGP_CAROLIEiJ_G0015069 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016899 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_103562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016878 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016831 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028301 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015869 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7873449 | J:23591
First Author: Rajan V
Year: 1995
Journal: J Steroid Biochem Mol Biol
Title: Cloning, sequencing and tissue-distribution of mouse 11 beta-hydroxysteroid dehydrogenase-1 cDNA.
Volume: 52
Issue: 2
Pages: 141-7
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Publication
7851387 | J:23036
First Author: Oppermann UC
Year: 1995
Journal: Eur J Biochem
Title: Cloning and primary structure of murine 11 beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase.
Volume: 227
Issue: 1-2
Pages: 202-8
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Publication
8973338 | J:37988
First Author: Voice MW
Year: 1996
Journal: Gene
Title: The sequence of 5' flanking DNA from the mouse 11 beta-hydroxysteroid dehydrogenase type 1 gene and analysis of putative transcription factor binding sites.
Volume: 181
Issue: 1-2
Pages: 233-5
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Publication
9405715 | J:45085
First Author: Kotelevtsev Y
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress.
Volume: 94
Issue: 26
Pages: 14924-9
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Publication
24169553 | J:207713
First Author: Harno E
Year: 2013
Journal: Endocrinology
Title: 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms.
Volume: 154
Issue: 12
Pages: 4580-93
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Publication
27384305 | J:240133
First Author: Larner DP
Year: 2016
Journal: Endocrinology
Title: Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.
Volume: 157
Issue: 9
Pages: 3493-504
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Publication
22555437 | J:189059
First Author: Lavery GG
Year: 2012
Journal: Endocrinology
Title: Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
Volume: 153
Issue: 7
Pages: 3236-48
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Publication
24889609 | J:211636
First Author: Morgan SA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: 11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess.
Volume: 111
Issue: 24
Pages: E2482-91
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Publication
27195053 | J:236052
First Author: Itoi-Ochi S
Year: 2016
Journal: Dermatoendocrinol
Title: Local corticosterone activation by 11β-hydroxysteroid dehydrogenase 1 in keratinocytes: the role in narrow-band UVB-induced dermatitis.
Volume: 8
Issue: 1
Pages: e1119958
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Publication
27070821 | J:233701
First Author: Terao M
Year: 2016
Journal: Am J Pathol
Title: Local Glucocorticoid Activation by 11β-Hydroxysteroid Dehydrogenase 1 in Keratinocytes: The Role in Hapten-Induced Dermatitis.
Volume: 186
Issue: 6
Pages: 1499-510
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Publication
24667799 | J:214146
First Author: Terao M
Year: 2014
Journal: PLoS One
Title: 11β-hydroxysteroid dehydrogenase 1 specific inhibitor increased dermal collagen content and promotes fibroblast proliferation.
Volume: 9
Issue: 3
Pages: e93051
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Publication
29062028 | J:255556
First Author: Vandermosten L
Year: 2017
Journal: Sci Rep
Title: 11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner.
Volume: 7
Issue: 1
Pages: 13835
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Publication
35097015 | J:319642
 
First Author: Wu J
Year: 2021
Journal: Front Cardiovasc Med
Title: Enhanced Angiogenesis by 11βHSD1 Blockage Is Insufficient to Improve Reperfusion Following Hindlimb Ischaemia.
Volume: 8
Pages: 795823
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Publication
29474943 | J:264080
First Author: Matsumoto A
Year: 2018
Journal: J Invest Dermatol
Title: Attenuated Activation of Homeostatic Glucocorticoid in Keratinocytes Induces Alloknesis via Aberrant Artemin Production.
Volume: 138
Issue: 7
Pages: 1491-1500
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Publication
23832962 | J:203302
First Author: Harno E
Year: 2013
Journal: Endocrinology
Title: 11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.
Volume: 154
Issue: 10
Pages: 3599-609
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Publication
- | J:37960
First Author: Kotelevtsev YV
Year: 1996
Journal: Endocr Res
Title: Inactivation of 11 beta-hydroxysteroid dehydrogenase type 1 by gene targeting in mice.
Volume: 22
Issue: 4
Pages: 791-792
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Publication
25614240 | J:253314
First Author: Yau JL
Year: 2015
Journal: Eur J Neurosci
Title: Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11β-HSD1-deficient mice: a microdialysis study in young and aged mice.
Volume: 41
Issue: 6
Pages: 787-92
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Publication
20943927 | J:165488
First Author: Sooy K
Year: 2010
Journal: J Neurosci
Title: Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice.
Volume: 30
Issue: 41
Pages: 13867-72
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Publication
15047607 | J:89080
First Author: Morton NM
Year: 2004
Journal: Diabetes
Title: Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.
Volume: 53
Issue: 4
Pages: 931-8
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Publication
16093320 | J:101151
First Author: Small GR
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis.
Volume: 102
Issue: 34
Pages: 12165-70
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Publication
20495186 | J:182116
First Author: McSweeney SJ
Year: 2010
Journal: Cardiovasc Res
Title: Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11betaHSD1-deficient mice post-MI.
Volume: 88
Issue: 1
Pages: 159-67
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Publication
14715714 | J:105643
First Author: Justesen J
Year: 2004
Journal: Endocrinology
Title: Mice deficient in 11beta-hydroxysteroid dehydrogenase type 1 lack bone marrow adipocytes, but maintain normal bone formation.
Volume: 145
Issue: 4
Pages: 1916-25
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Publication
16763061 | J:129642
First Author: Densmore VS
Year: 2006
Journal: Endocrinology
Title: 11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia?
Volume: 147
Issue: 9
Pages: 4486-95
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Publication
17170103 | J:119245
First Author: Paterson JM
Year: 2007
Journal: Endocrinology
Title: Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice.
Volume: 148
Issue: 3
Pages: 961-6
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Publication
19602102 | J:274412
First Author: Carter RN
Year: 2009
Journal: J Neuroendocrinol
Title: Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11beta-HSD1 is strain-dependent.
Volume: 21
Issue: 11
Pages: 879-87
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Publication
11546766 | J:72402
First Author: Morton NM
Year: 2001
Journal: J Biol Chem
Title: Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice.
Volume: 276
Issue: 44
Pages: 41293-300
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Publication
11145573 | J:110703
First Author: Harris HJ
Year: 2001
Journal: Endocrinology
Title: Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice.
Volume: 142
Issue: 1
Pages: 114-20
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Publication
21350084 | J:171754
First Author: Wamil M
Year: 2011
Journal: Diabetes
Title: Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice.
Volume: 60
Issue: 4
Pages: 1158-67
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Publication
23349944 | J:195838
First Author: Coutinho AE
Year: 2013
Journal: PLoS One
Title: Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation.
Volume: 8
Issue: 1
Pages: e54640
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Publication
29203512 | J:257840
First Author: Fine NHF
Year: 2018
Journal: Diabetes
Title: Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.
Volume: 67
Issue: 2
Pages: 278-290
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Publication
22158867 | J:181515
First Author: Michailidou Z
Year: 2012
Journal: J Biol Chem
Title: Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice.
Volume: 287
Issue: 6
Pages: 4188-97
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Publication
16751407 | J:132352
First Author: Gilmour JS
Year: 2006
Journal: J Immunol
Title: Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes.
Volume: 176
Issue: 12
Pages: 7605-11
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Publication
17008390 | J:129562
First Author: Dover AR
Year: 2007
Journal: Endocrinology
Title: Intravascular glucocorticoid metabolism during inflammation and injury in mice.
Volume: 148
Issue: 1
Pages: 166-72
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Publication
21411659 | J:170452
First Author: Yau JL
Year: 2011
Journal: J Neurosci
Title: 11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control.
Volume: 31
Issue: 11
Pages: 4188-93
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Publication
25109766 | J:218322
First Author: Yau JL
Year: 2015
Journal: Neurobiol Aging
Title: Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice.
Volume: 36
Issue: 1
Pages: 334-43
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Publication
17898220 | J:125287
First Author: Yau JL
Year: 2007
Journal: J Neurosci
Title: Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice.
Volume: 27
Issue: 39
Pages: 10487-96
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Publication
11274359 | J:68825
First Author: Yau JL
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments.
Volume: 98
Issue: 8
Pages: 4716-21
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Publication
28368470 | J:245940
First Author: Doig CL
Year: 2017
Journal: Endocrinology
Title: 11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice.
Volume: 158
Issue: 6
Pages: 1964-1976
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Publication
34072239 | J:331217
 
First Author: Kim BJ
Year: 2021
Journal: Int J Mol Sci
Title: Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin.
Volume: 22
Issue: 11
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Publication
37936704 | J:342418
 
First Author: Merk VM
Year: 2023
Journal: Front Immunol
Title: Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice.
Volume: 14
Pages: 1252874
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Publication
20739946 | J:270993
First Author: Tiganescu A
Year: 2011
Journal: J Invest Dermatol
Title: Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin.
Volume: 131
Issue: 1
Pages: 30-6
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Publication
23633532 | J:198945
First Author: Morgan SA
Year: 2013
Journal: Endocrinology
Title: Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle.
Volume: 154
Issue: 7
Pages: 2374-84
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Publication
37180160 | J:345999
 
First Author: Mahida RY
Year: 2023
Journal: Front Immunol
Title: Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS.
Volume: 14
Pages: 1159831
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Publication
23722901 | J:201433
First Author: Tiganescu A
Year: 2013
Journal: J Clin Invest
Title: 11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects.
Volume: 123
Issue: 7
Pages: 3051-60
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Publication
33214595 | J:299999
First Author: Lee NR
Year: 2020
Journal: Sci Rep
Title: Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis.
Volume: 10
Issue: 1
Pages: 20237
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Publication
10411326 | J:55967
First Author: Krozowski Z
Year: 1999
Journal: Mol Cell Endocrinol
Title: The 11beta-hydroxysteroid dehydrogenases: functions and physiological effects.
Volume: 151
Issue: 1-2
Pages: 121-7
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Publication
12765951 | J:83537
First Author: Liu Y
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Title: The expression of 11 beta-hydroxysteroid dehydrogenase type I by lymphocytes provides a novel means for intracrine regulation of glucocorticoid activities.
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Title: Skeletal muscle 11beta-HSD1 controls glucocorticoid-induced proteolysis and expression of E3 ubiquitin ligases atrogin-1 and MuRF-1.
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