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Search results 1 to 100 out of 137 for Hsd17b3

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
3293 | HSD17B3
Type: gene
Organism: human
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Gene
101730254 | hsd17b3
Type: gene
Organism: frog, western clawed
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Gene
117182 | Hsd17b3
Type: gene
Organism: rat
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Gene
742116 | HSD17B3
Type: gene
Organism: chimpanzee
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Gene
616934 | HSD17B3
Type: gene
Organism: cattle
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Gene
100856708 | HSD17B3
Type: gene
Organism: dog, domestic
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Gene
427474 | HSD17B3
Type: gene
Organism: chicken
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Gene
393335 | hsd17b3
Type: gene
Organism: zebrafish
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Gene
709843 | HSD17B3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:107177 | Hsd17b3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033281 | HSD17B3
Type: Family
Description: Testosterone 17-beta-dehydrogenase 3 (HSD17B3) is involved in the pathway testosterone biosynthesis. It catalyses the conversion of the androstenedione to testosterone, which is responsible for the normal fetal development of male genitalia. It is predominantly expressed in the testes and utilizes NADPH as a cofactor. Mutations in the HSD17B3 gene cause 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) deficiency cause 46, XY Disorders of Sex Development (46, XY DSD) [].
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Gene
105376162 | HSD17B3-AS1
Type: gene
Organism: human
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Publication
32190925 | J:301756
First Author: Sipilä P
Year: 2020
Journal: FASEB J
Title: The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency.
Volume: 34
Issue: 5
Pages: 6111-6128
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Publication
26545797 | -
First Author: Engeli RT
Year: 2016
Journal: J Steroid Biochem Mol Biol
Title: Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development.
Volume: 155
Issue: Pt A
Pages: 147-54
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Protein
A0A1Y7VJL6
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Protein
A0A1Y7VJ36
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
P70385
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
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Publication
32557858 | J:302854
First Author: Rebourcet D
Year: 2020
Journal: FASEB J
Title: Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production.
Volume: 34
Issue: 8
Pages: 10373-10386
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Publication
24979775 | J:212156
First Author: Howerton CL
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction.
Volume: 111
Issue: 26
Pages: 9639-44
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Protein Coding Gene
MGP_CAROLIEiJ_G0018636 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020672 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020419 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107177 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020379 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019700 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019516 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23183177 | J:354168
First Author: Legeza B
Year: 2013
Journal: Endocrinology
Title: The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase.
Volume: 154
Issue: 1
Pages: 205-13
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029844
Age: postnatal day 30
Specimen Label: Type 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:3029847
Age: embryonic day 15.5
Specimen Label: fetal 15.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797225
Stage: TS25
Assay Id: MGI:3029847
Age: embryonic day 17.0
Specimen Label: fetal 17.0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:3029847
Age: postnatal day 1
Specimen Label: postnatal 1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 5
Specimen Label: postnatal day 5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 10
Specimen Label: postnatal day 10
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 20
Specimen Label: postnatal day 20
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 25
Specimen Label: postnatal day 25
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 30
Specimen Label: postnatal day 30
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3029491
Assay Type: RT-PCR
Annotation Date: 2004-03-10
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3029847
Age: postnatal day 90
Specimen Label: postnatal day 90
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Ovary
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Uterus
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Placenta
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Mammary glands
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Adrenals
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6162031
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Adrenals
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1928728
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Prostate
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6162042
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6162106
Age: embryonic day 7.0
Specimen Label: 7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6162106
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6162106
Age: embryonic day 15.0
Specimen Label: 15
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6161680
Assay Type: Northern blot
Annotation Date: 2018-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6162106
Age: embryonic day 17.0
Specimen Label: 17
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7486092
Assay Type: RT-PCR
Annotation Date: 2023-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:7486177
Age: postnatal week 4
Image: 3
Specimen Label: XX wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7486092
Assay Type: RT-PCR
Annotation Date: 2023-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7486177
Age: postnatal week 4
Image: 3
Specimen Label: XY wt
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7641308
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:7641506
Age: embryonic day 15.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7641308
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:7641506
Age: embryonic day 15.5
Specimen Label: HET
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7641308
Assay Type: RT-PCR
Annotation Date: 2024-05-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:7641506
Age: embryonic day 15.5
Specimen Label: HOM
Detected: true
Specimen Num: 3
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Publication
30793514 | J:308912
First Author: Bergeron F
Year: 2019
Journal: Andrology
Title: Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse.
Volume: 7
Issue: 3
Pages: 357-372
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Publication
25668066 | J:222045
First Author: Padua MB
Year: 2015
Journal: Endocrinology
Title: Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes.
Volume: 156
Issue: 5
Pages: 1873-86
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Publication
9182854 | J:40790
First Author: Sha JA
Year: 1997
Journal: J Steroid Biochem Mol Biol
Title: Sequence of mouse 17beta-hydroxysteroid dehydrogenase type 3 cDNA and tissue distribution of the type 1 and type 3 isoform mRNAs.
Volume: 60
Issue: 1-2
Pages: 19-24
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Publication
23125070 | J:277704
First Author: Shima Y
Year: 2013
Journal: Mol Endocrinol
Title: Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes.
Volume: 27
Issue: 1
Pages: 63-73
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Publication
8630080 | J:33772
First Author: Sha J
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Both reductive forms of 17 beta-hydroxysteroid dehydrogenase (types 1 and 3) are expressed during development in the mouse testis.
Volume: 222
Issue: 1
Pages: 90-4
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Publication
9406858 | J:44106
First Author: Baker PJ
Year: 1997
Journal: Mol Cell Endocrinol
Title: Localisation and regulation of 17beta-hydroxysteroid dehydrogenase type 3 mRNA during development in the mouse testis.
Volume: 133
Issue: 2
Pages: 127-33
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Publication
9224647 | J:41672
 
First Author: Mustonen MV
Year: 1997
Journal: Biochem J
Title: Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.
Volume: 325 ( Pt 1)
Pages: 199-205
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Publication
12537567 | J:82019
First Author: Marshall KE
Year: 2002
Journal: Genome Biol
Title: In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases.
Volume: 3
Issue: 12
Pages: RESEARCH0078
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Publication
27732090 | J:240774
First Author: Umehara T
Year: 2016
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