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Search results 1 to 69 out of 69 for Hsh2d

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Hits by Category

Hits by Strain

Type Details Score
Gene
84941 | HSH2D
Type: gene
Organism: human
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Gene
105945618 | hsh2d
Type: gene
Organism: frog, western clawed
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Gene
484852 | HSH2D
Type: gene
Organism: dog, domestic
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Gene
100360518 | Hsh2d
Type: gene
Organism: rat
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Gene
100613207 | HSH2D
Type: gene
Organism: chimpanzee
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Gene
100848273 | HSH2D
Type: gene
Organism: cattle
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Gene
548337 | hsh2d
Type: gene
Organism: zebrafish
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Gene
719440 | HSH2D
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR035047 | HSH2D
Type: Family
Description: HSH2D (hematopoietic SH2 domain-containing protein, also known as ALX) is an adapter protein involved in tyrosine kinase and CD28 signaling []. It is expressed exclusively in hematopoietic cells. It contains an Src homology 2 (SH2) domain, four PXXP polyproline sequences, and two likely sites of tyrosine phosphorylation. The SH2 domain plays a critical role in ALX function downstream of CD28 [].
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Protein Coding Gene
MGI:2676364 | Hsh2d
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12960172 | J:85736
First Author: Greene TA
Year: 2003
Journal: J Biol Chem
Title: Cloning and characterization of ALX, an adaptor downstream of CD28.
Volume: 278
Issue: 46
Pages: 45128-34
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Publication
15284240 | -
First Author: Shapiro MJ
Year: 2004
Journal: J Biol Chem
Title: The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP.
Volume: 279
Issue: 39
Pages: 40647-52
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Protein
Q6VYH9
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0031212 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033683 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2676364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033538 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033682 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033582 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034288 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021677 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032332 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15569688 | J:96984
First Author: Herrin BR
Year: 2005
Journal: J Biol Chem
Title: The adaptor protein HSH2 attenuates apoptosis in response to ligation of the B cell antigen receptor complex on the B lymphoma cell line, WEHI-231.
Volume: 280
Issue: 5
Pages: 3507-15
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Publication
16547253 | J:129911
First Author: Herrin BR
Year: 2006
Journal: J Immunol
Title: Expression of the adaptor protein hematopoietic Src homology 2 is up-regulated in response to stimuli that promote survival and differentiation of B cells.
Volume: 176
Issue: 7
Pages: 4163-72
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Publication
21873522 | J:179338
First Author: King RG
Year: 2011
Journal: J Immunol
Title: Differential expression of the adaptor protein HSH2 controls the quantitative and qualitative nature of the humoral response.
Volume: 187
Issue: 7
Pages: 3565-77
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: heart
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: liver
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: spleen
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: kidney
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: lung
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: thymus
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: testis
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4418653
Age: postnatal
Image: 2
Specimen Label: ovary
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:4418652
Assay Type: Northern blot
Annotation Date: 2010-01-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:4418653
Age: embryonic day 10.0-11.0
Image: 2
Specimen Label: embryo
Detected: false
Specimen Num: 6
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Publication
17641043 | J:149941
First Author: Perchonock CE
Year: 2007
Journal: J Immunol
Title: The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes.
Volume: 179
Issue: 3
Pages: 1768-75
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Publication
16880512 | J:111408
First Author: Perchonock CE
Year: 2006
Journal: Mol Cell Biol
Title: Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX.
Volume: 26
Issue: 16
Pages: 6005-15
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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