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Search results 1 to 100 out of 561 for Htra1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Tsuchiya A
Year: 2005
Journal: Bone
Title: Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis.
Volume: 37
Issue: 3
Pages: 323-36
Publication
First Author: Oka C
Year: 2004
Journal: Development
Title: HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins.
Volume: 131
Issue: 5
Pages: 1041-53
Publication
First Author: Launay S
Year: 2008
Journal: Cell Death Differ
Title: HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival.
Volume: 15
Issue: 9
Pages: 1408-16
Publication
First Author: Zhang L
Year: 2012
Journal: J Biol Chem
Title: High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6.
Volume: 287
Issue: 2
Pages: 1520-6
Publication
First Author: Campbell RA
Year: 2021
Journal: Blood
Title: Placental HTRA1 cleaves α1-antitrypsin to generate a NET-inhibitory peptide.
Volume: 138
Issue: 11
Pages: 977-988
Publication
First Author: De Luca A
Year: 2004
Journal: J Histochem Cytochem
Title: Pattern of expression of HtrA1 during mouse development.
Volume: 52
Issue: 12
Pages: 1609-17
Publication
First Author: Ferrer-Vaquer A
Year: 2008
Journal: Dev Dyn
Title: Expression and regulation of HTRA1 during chick and early mouse development.
Volume: 237
Issue: 7
Pages: 1893-900
Publication  
First Author: Nigro A
Year: 2012
Journal: Cell Death Dis
Title: MiR-30e and miR-181d control radial glia cell proliferation via HtrA1 modulation.
Volume: 3
Pages: e360
Publication
First Author: Klose R
Year: 2018
Journal: Oncogene
Title: Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesis.
Volume: 37
Issue: 31
Pages: 4260-4272
Publication
First Author: Klose R
Year: 2019
Journal: Sci Rep
Title: Loss of the serine protease HTRA1 impairs smooth muscle cells maturation.
Volume: 9
Issue: 1
Pages: 18224
Publication
First Author: Filliat G
Year: 2017
Journal: PLoS One
Title: Role of HTRA1 in bone formation and regeneration: In vitro and in vivo evaluation.
Volume: 12
Issue: 7
Pages: e0181600
Publication
First Author: Ikawati M
Year: 2018
Journal: PLoS One
Title: Loss of HtrA1 serine protease induces synthetic modulation of aortic vascular smooth muscle cells.
Volume: 13
Issue: 5
Pages: e0196628
Publication  
First Author: Supanji
Year: 2013
Journal: Exp Eye Res
Title: HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway.
Volume: 112
Pages: 79-92
Publication
First Author: Ciferri C
Year: 2015
Journal: Biochem J
Title: The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.
Volume: 472
Issue: 2
Pages: 169-81
Publication
First Author: Wu X
Year: 2014
Journal: FEBS Lett
Title: HtrA1 is upregulated during RANKL-induced osteoclastogenesis, and negatively regulates osteoblast differentiation and BMP2-induced Smad1/5/8, ERK and p38 phosphorylation.
Volume: 588
Issue: 1
Pages: 143-50
Publication
First Author: Nie G
Year: 2005
Journal: Dev Dyn
Title: Serine protease HtrA1 is developmentally regulated in trophoblast and uterine decidual cells during placental formation in the mouse.
Volume: 233
Issue: 3
Pages: 1102-9
Publication
First Author: Graham JR
Year: 2013
Journal: PLoS One
Title: Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation.
Volume: 8
Issue: 9
Pages: e74094
Publication
First Author: Chen J
Year: 2018
Journal: J Neurosci
Title: BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response.
Volume: 38
Issue: 15
Pages: 3840-3857
Publication
First Author: Beaufort N
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling.
Volume: 111
Issue: 46
Pages: 16496-501
Publication
First Author: Nakayama M
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Overexpression of HtrA1 and exposure to mainstream cigarette smoke leads to choroidal neovascularization and subretinal deposits in aged mice.
Volume: 55
Issue: 10
Pages: 6514-23
Publication  
First Author: Wright AA
Year: 2020
Journal: Mol Cell Neurosci
Title: Macrophage migration inhibitory factor and its binding partner HTRA1 are expressed by olfactory ensheathing cells.
Volume: 102
Pages: 103450
Publication
First Author: Jones A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice.
Volume: 108
Issue: 35
Pages: 14578-83
Publication
First Author: Murwantoko
Year: 2004
Journal: Biochem J
Title: Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease.
Volume: 381
Issue: Pt 3
Pages: 895-904
Publication    
First Author: Patterson VL
Year: 2016
Journal: J Vis Exp
Title: A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging.
Issue: 113
Publication
First Author: Kumar S
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epithelium.
Volume: 55
Issue: 6
Pages: 3842-50
Publication
First Author: Chen PH
Year: 2019
Journal: Am J Pathol
Title: High-Temperature Requirement A1 Protease as a Rate-Limiting Factor in the Development of Osteoarthritis.
Volume: 189
Issue: 7
Pages: 1423-1434
Publication
First Author: Friedrich U
Year: 2011
Journal: Hum Mol Genet
Title: Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency.
Volume: 20
Issue: 7
Pages: 1387-99
UniProt Feature
Begin: 23
Description: Serine protease HTRA1
Type: chain
End: 480
Publication
First Author: Hasan MZ
Year: 2015
Journal: Dev Biol
Title: Abnormal development of placenta in HtrA1-deficient mice.
Volume: 397
Issue: 1
Pages: 89-102
Publication
First Author: Muratoglu SC
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1.
Volume: 33
Issue: 9
Pages: 2137-46
Publication
First Author: Tocharus J
Year: 2004
Journal: Dev Growth Differ
Title: Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling.
Volume: 46
Issue: 3
Pages: 257-74
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Liu J
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Postnatal overexpression of the human ARMS2 gene does not induce abnormalities in retina and choroid in transgenic mouse models.
Volume: 56
Issue: 2
Pages: 1387-8
GXD Expression    
Probe: MGI:3703342
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Stage: TS04
Assay Id: MGI:3703536
Age: embryonic day 3.5
Image: 5
Specimen Label: -/-, 3.5dpc
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3703342
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3703536
Age: embryonic day 4.5
Image: 5
Specimen Label: -/-, 4.5dpc
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5292005
Assay Type: RT-PCR
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293690
Age: embryonic day 16.5
Specimen Label: M
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5292005
Assay Type: RT-PCR
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293690
Age: embryonic day 16.5
Specimen Label: D
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5292005
Assay Type: RT-PCR
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293690
Age: embryonic day 16.5
Specimen Label: L
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5292005
Assay Type: RT-PCR
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293690
Age: embryonic day 16.5
Specimen Label: R
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5292005
Assay Type: RT-PCR
Annotation Date: 2011-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293690
Age: embryonic day 16.5
Specimen Label: O
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5751281
Assay Type: Western blot
Annotation Date: 2016-03-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5751526
Age: embryonic day 10.5
Image: S1
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5751281
Assay Type: Western blot
Annotation Date: 2016-03-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5751526
Age: embryonic day 10.5
Image: S1
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5751281
Assay Type: Western blot
Annotation Date: 2016-03-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5751526
Age: embryonic day 10.5
Image: S1
Specimen Label: -/-
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:5751281
Assay Type: Western blot
Annotation Date: 2016-03-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5751526
Age: embryonic day 10.5
Image: S1
Specimen Label: -/-
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:3703342
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Stage: TS04
Assay Id: MGI:3703536
Age: embryonic day 3.5
Image: 5
Specimen Label: +/?, 3.5dpc
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3703342
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3703536
Age: embryonic day 4.5
Image: 5
Specimen Label: +/?, 4.5dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6444316
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445559
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6444316
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445559
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6456718
Assay Type: Northern blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:6457112
Age: embryonic day 8.0
Specimen Label: 8 dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6456718
Assay Type: Northern blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:6457112
Age: embryonic day 12.0
Specimen Label: 12 dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6456718
Assay Type: Northern blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:6457112
Age: embryonic day 16.0
Specimen Label: 16 dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6456718
Assay Type: Northern blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6457112
Age: embryonic day 19.0
Specimen Label: 19 dpc
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:6457114
Age: embryonic day 13.0
Specimen Label: None
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:6457114
Age: embryonic day 13.0
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:6457114
Age: embryonic day 13.0
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:6457114
Age: embryonic day 13.0
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691023
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689623
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756323
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755023
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:6457115
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535726
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3531326
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280926
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754926
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754026
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753626
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697426
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756326
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755026
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:6456721
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:6457116
Age: embryonic day 18.0
Specimen Label: None
Detected: true
Specimen Num: 12