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Search results 1 to 68 out of 68 for Hypk

0.031s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
25764 | HYPK
Type: gene
Organism: human
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Gene
100145587 | hypk
Type: gene
Organism: frog, western clawed
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Gene
104002286 | HYPK
Type: gene
Organism: chimpanzee
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Gene
311359 | Hypk
Type: gene
Organism: rat
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Gene
487528 | HYPK
Type: gene
Organism: dog, domestic
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Gene
100138230 | HYPK
Type: gene
Organism: cattle
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Gene
770307 | HYPK
Type: gene
Organism: chicken
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Gene
100151755 | hypk
Type: gene
Organism: zebrafish
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Gene
713266 | HYPK
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914943 | Hypk
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27017930 | J:230852
First Author: Das S
Year: 2016
Journal: Exp Cell Res
Title: Huntingtin interacting protein HYPK is a negative regulator of heat shock response and is downregulated in models of Huntington's Disease.
Volume: 343
Issue: 2
Pages: 107-117
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Publication
25446099 | J:220288
First Author: Choudhury KR
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.
Volume: 456
Issue: 1
Pages: 66-73
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Protein Coding Gene
MGP_CAROLIEiJ_G0024196 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026356 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026871 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025646 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025638 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025112 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:1699814
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825833
Age: embryonic day 14.5
Image: Additional file 4 2310003F16Rik
Specimen Label: Additional file 4 2310003F16Rik
Detected: true
Specimen Num: 1
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
18076027 | -
First Author: Raychaudhuri S
Year: 2008
Journal: Proteins
Title: Huntingtin interacting protein HYPK is intrinsically unstructured.
Volume: 71
Issue: 4
Pages: 1686-98
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Publication
20154145 | -
First Author: Arnesen T
Year: 2010
Journal: Mol Cell Biol
Title: The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.
Volume: 30
Issue: 8
Pages: 1898-909
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Publication
23272104 | -
First Author: Choudhury KR
Year: 2012
Journal: PLoS One
Title: Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death.
Volume: 7
Issue: 12
Pages: e51415
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Publication
29754825 | -
First Author: Gottlieb L
Year: 2018
Journal: Structure
Title: Structure of Human NatA and Its Regulation by the Huntingtin Interacting Protein HYPK.
Volume: 26
Issue: 7
Pages: 925-935.e8
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Protein Domain
IPR044034 | NAC-like_UBA
Type: Domain
Description: In eukaryotes, the Nascent polypeptide-Associated Complex (NAC) is a heterodimeric cytosolic protein complex composed of alpha and beta subunits. NAC binds reversibly to the ribosome where it is in contact with nascent chains as they emerge from the ribosome and protects them against inappropriate interaction with cytosolic factors. However, the cellular function of NAC seems to be much more diverse as it is also involved in transcription regulation and mitochondrial translocation []. Alpha and beta NACs share homology with each other, both contain a NAC A/B domain, responsible for the complex dimerisation. In archaea no beta NAC proteins are found; the complex is an homodimer of NAC alpha [, ]. These proteins have an additional ubiquitin-associated (UBA) domain which suggests the involvement of NAC in the cellular protein quality control system via the ubiquitination pathway [].This entry represents the UBA domain found at the C-terminal of the Nascent polypeptide-Associated Complex (NAC) subunit alpha. This domain is also found in HYPK (Huntingtin-interacting protein K) in which mediates a constitutively protein interaction with Naa15 auxiliary subunit from N-terminal acetyltransferase NatA. NatA associates with the ribosome and nascent polypeptides, suggesting that HYPK also interacts with these polypeptides possibly to facilitate Nt-acetylation fidelity [].
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Protein
Q9CR41
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: false
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Publication
21887328 | J:176149
First Author: Ghose J
Year: 2011
Journal: PLoS One
Title: Regulation of miR-146a by RelA/NFkB and p53 in STHdh(Q111)/Hdh(Q111) cells, a cell model of Huntington's disease.
Volume: 6
Issue: 8
Pages: e23837
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Protein
P70670
Organism: Mus musculus/domesticus
Length: 2187  
Fragment?: false
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Protein
Q60817
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q3UK68
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein
Q5SWP3
Organism: Mus musculus/domesticus
Length: 1504  
Fragment?: false
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Publication
10413400 | -
First Author: Makarova KS
Year: 1999
Journal: Genome Res
Title: Comparative genomics of the Archaea (Euryarchaeota): evolution of conserved protein families, the stable core, and the variable shell.
Volume: 9
Issue: 7
Pages: 608-28
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Publication
15665334 | -
First Author: Spreter T
Year: 2005
Journal: J Biol Chem
Title: The crystal structure of archaeal nascent polypeptide-associated complex (NAC) reveals a unique fold and the presence of a ubiquitin-associated domain.
Volume: 280
Issue: 16
Pages: 15849-54
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Publication
12475173 | -
First Author: Rospert S
Year: 2002
Journal: Cell Mol Life Sci
Title: Nascent-polypeptide-associated complex.
Volume: 59
Issue: 10
Pages: 1632-9
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