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Search results 1 to 100 out of 262 for Iapp

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
3375 | IAPP
Type: gene
Organism: human
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Gene
114670806 | IAPP
Type: gene
Organism: macaque, rhesus
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Gene
116409452 | iapp
Type: gene
Organism: frog, western clawed
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Gene
key_18915 | IAPP
Type: gene
Organism: sheep
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Gene
24476 | Iapp
Type: gene
Organism: rat
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Gene
403909 | IAPP
Type: gene
Organism: dog, domestic
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Gene
741937 | IAPP
Type: gene
Organism: chimpanzee
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Gene
100138011 | IAPP
Type: gene
Organism: cattle
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Gene
396362 | IAPP
Type: gene
Organism: chicken
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Gene
100334757 | iapp
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:96382 | Iapp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR000443 | IAPP
Type: Family
Description: Islet amyloid polypeptide (IAPP) (also known as diabetes-associated peptideor amylin) is a pancreatic islet hormone that is stored with insulin in betacell granules []. IAPP has a propensity to form islet cell-disrupting amyloid deposits, and opposes the action of insulin in peripheral tissues; the peptide may therefore have a significant role in the development of Type2 diabetes mellitus []. It is thought that an intrinsic structural motif ofIAPP, which only occurs in species that develop age-associated or Type 2 diabetes (e.g., Homo sapiens (Human) and Felis silvestris catus (Cat)), is linked to its amyloidogenicity [].IAPP is a short, 37-residue peptide. The hormone selectively inhibits insulin-stimulated glucose utilisation and glycogen deposition in muscle,but does not affect adipocyte glucose metabolism. The sequences of amylinand the calcitonin gene-related peptides (CGRPs) show strong similarity:both peptides have a conserved N-terminal intramolecular disulphide bridge,and both have a C-terminal glycine, which suggests that the C-terminalresidue of amylin, like that of CGRP, is amidated [].Near- and far-UV CD spectra of human alpha CGRP, analogues and fragments ofCGRP, and amylin have been recorded in aqueous solution and in trifluoro-ethanol/water mixtures []. The peptides were shown to contain significantamounts of α-helix in aqueous solution, this amount increasing upon addition of TFE. Amylin appears to contain less helix than CGRP [].
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6441722
Age: embryonic day 18.5
Image: 3 e18.5 IAPP
Note: Proportion of Gcg-expressing cells expressing Iapp falls to approximately 20%.
Specimen Label: 3 e18.5 IAPP
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6441723
Age: embryonic day 10.5
Image: 4 IAPP
Note: Most Iapp-expressing cells do not express Pdx1.
Specimen Label: 4 IAPP
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6441722
Age: embryonic day 12.5
Image: 3 e12.5 (upper) IAPP
Note: Co-expression with proglucagon continues throughout fetal development of pancreas. At E12.5, co-expression in majority of Gcg-expressing cells.
Specimen Label: 3 e12.5 (upper) IAPP
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6441722
Age: embryonic day 12.5
Image: 3 e12.5 (lower) IAPP
Note: Expression in all insulin-expressing cells.
Specimen Label: 3 e12.5 (lower) IAPP
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6441722
Age: embryonic day 15.5
Image: 3 e15.5 IAPP
Note: Expression in about 60% of Gcg-expressing cells.
Specimen Label: 3 e15.5 IAPP
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825756
Age: embryonic day 14.5
Image: Additional file 4 Iapp
Specimen Label: Additional file 4 Iapp
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6441722
Age: embryonic day 10.5
Image: 3 e10.5 IAPP
Note: Expression in pancreatic bud first appears at E10.5. Co-expression with proglucagon.
Specimen Label: 3 e10.5 IAPP
Detected: true
Specimen Num: 1
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Publication
2192709 | -
First Author: Jordan K
Year: 1990
Journal: Biochem Biophys Res Commun
Title: Canine IAPP cDNA sequence provides important clues regarding diabetogenesis and amyloidogenesis in type 2 diabetes.
Volume: 169
Issue: 2
Pages: 502-8
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Publication
28765400 | J:244694
First Author: Mukherjee A
Year: 2017
Journal: J Exp Med
Title: Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism.
Volume: 214
Issue: 9
Pages: 2591-2610
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Publication
- | J:23849
 
First Author: Prochazka M
Year: 1991
Journal: Mouse Genome
Title: Mapping of Iapp and Kap genes to Chr. 6
Volume: 89
Pages: 553
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Publication
- | J:20644
     
First Author: Prochazka M
Year: 1991
Journal: Personal Communication
Title: Linkage of mouse NKR P1 gene to Ly-49 and Iapp on Chromosome 6
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Protein
P12968
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
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Publication
2039456 | -
 
First Author: Hubbard JA
Year: 1991
Journal: Biochem J
Title: Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin.
Volume: 275 ( Pt 3)
Pages: 785-8
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Publication
2690069 | -
First Author: Roberts AN
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Molecular and functional characterization of amylin, a peptide associated with type 2 diabetes mellitus.
Volume: 86
Issue: 24
Pages: 9662-6
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Publication
12049785 | J:77320
First Author: Wilson ME
Year: 2002
Journal: Mech Dev
Title: Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas.
Volume: 115
Issue: 1-2
Pages: 171-6
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Publication
26209627 | J:319572
First Author: Viret C
Year: 2015
Journal: J Immunol
Title: The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens.
Volume: 195
Issue: 5
Pages: 1964-73
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Publication
8692984 | J:47215
First Author: Janson J
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.
Volume: 93
Issue: 14
Pages: 7283-8
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Publication
32728889 | J:298717
First Author: Templin AT
Year: 2020
Journal: Diabetologia
Title: Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
Volume: 63
Issue: 11
Pages: 2385-2395
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Publication
23229548 | J:335478
First Author: Aston-Mourney K
Year: 2013
Journal: J Biol Chem
Title: Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide.
Volume: 288
Issue: 5
Pages: 3553-9
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Publication
8690157 | J:73886
First Author: Couce M
Year: 1996
Journal: Diabetes
Title: Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction.
Volume: 45
Issue: 8
Pages: 1094-101
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Publication
12086946 | J:132801
First Author: Geisler JG
Year: 2002
Journal: Diabetes
Title: Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.
Volume: 51
Issue: 7
Pages: 2158-69
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Publication
27393137 | J:237059
First Author: Meier DT
Year: 2016
Journal: Diabetologia
Title: The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
Volume: 59
Issue: 10
Pages: 2166-71
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Publication
24843557 | J:241122
First Author: Hiddinga HJ
Year: 2012
Journal: J Diabetes Investig
Title: Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance.
Volume: 3
Issue: 2
Pages: 138-47
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Publication
12637985 | J:82403
First Author: Vidal J
Year: 2003
Journal: Diabetologia
Title: The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
Volume: 46
Issue: 1
Pages: 71-9
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Publication
15899941 | J:101262
First Author: Hull RL
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice.
Volume: 289
Issue: 4
Pages: E703-9
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Publication
11679429 | J:72413
First Author: Wang F
Year: 2001
Journal: Diabetes
Title: Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.
Volume: 50
Issue: 11
Pages: 2514-20
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Publication
11118007 | J:66008
First Author: Andrikopoulos S
Year: 2000
Journal: Diabetes
Title: beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
Volume: 49
Issue: 12
Pages: 2056-62
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Publication
8495745 | J:83219
First Author: Fox N
Year: 1993
Journal: FEBS Lett
Title: Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).
Volume: 323
Issue: 1-2
Pages: 40-4
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Publication
35136064 | J:333177
First Author: Fukumitsu K
Year: 2022
Journal: Nat Commun
Title: Amylin-Calcitonin receptor signaling in the medial preoptic area mediates affiliative social behaviors in female mice.
Volume: 13
Issue: 1
Pages: 709
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Publication
9838101 | J:51556
First Author: Gebre-Medhin S
Year: 1998
Journal: Brain Res Mol Brain Res
Title: Reduced nociceptive behavior in islet amyloid polypeptide (amylin) knockout mice.
Volume: 63
Issue: 1
Pages: 180-3
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Publication
9278863 | J:42671
First Author: Ekawa K
Year: 1997
Journal: J Mol Endocrinol
Title: Cloning of mouse islet amyloid polypeptide gene and characterization of its promoter.
Volume: 19
Issue: 1
Pages: 79-86
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Publication
9753619 | J:50042
First Author: Gebre-Medhin S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin).
Volume: 250
Issue: 2
Pages: 271-7
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Publication
11474116 | J:134181
First Author: Westermark GT
Year: 2000
Journal: Mol Med
Title: Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP.
Volume: 6
Issue: 12
Pages: 998-1007
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Publication
21734016 | J:186801
First Author: Delong T
Year: 2011
Journal: Diabetes
Title: Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.
Volume: 60
Issue: 9
Pages: 2325-30
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Publication
25700985 | J:220250
First Author: Oskarsson ME
Year: 2015
Journal: Am J Pathol
Title: In vivo seeding and cross-seeding of localized amyloidosis: a molecular link between type 2 diabetes and Alzheimer disease.
Volume: 185
Issue: 3
Pages: 834-46
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Publication
10751203 | J:62402
First Author: Mulder H
Year: 2000
Journal: Am J Physiol Endocrinol Metab
Title: Islet amyloid polypeptide (amylin)-deficient mice develop a more severe form of alloxan-induced diabetes.
Volume: 278
Issue: 4
Pages: E684-91
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Publication
11751075 | J:73918
First Author: Carlsson PO
Year: 2002
Journal: Eur J Endocrinol
Title: Unaltered pancreatic islet blood perfusion in islet amyloid polypeptide-deficient mice.
Volume: 146
Issue: 1
Pages: 107-12
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Publication
11731221 | J:73308
First Author: Jaikaran ET
Year: 2001
Journal: Biochim Biophys Acta
Title: Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
Volume: 1537
Issue: 3
Pages: 179-203
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Publication
8076756 | J:20486
First Author: Mulder H
Year: 1994
Journal: Gastroenterology
Title: Islet amyloid polypeptide is expressed in endocrine cells of the gastric mucosa in the rat and mouse.
Volume: 107
Issue: 3
Pages: 712-9
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Publication
10230646 | J:54393
First Author: Höppener JW
Year: 1999
Journal: Diabetologia
Title: Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
Volume: 42
Issue: 4
Pages: 427-34
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Publication
26786104 | J:233729
First Author: Westwell-Roper C
Year: 2016
Journal: J Biol Chem
Title: Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
Volume: 291
Issue: 17
Pages: 8908-17
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Publication
24043895 | J:206266
First Author: Baker RL
Year: 2013
Journal: J Immunol
Title: Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.
Volume: 191
Issue: 8
Pages: 3990-4
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Publication
2668946 | J:9937
First Author: Nishi M
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.
Volume: 86
Issue: 15
Pages: 5738-42
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Publication
1423499 | J:2137
First Author: Ahrén B
Year: 1992
Journal: Cell Tissue Res
Title: Localization of calcitonin gene-related peptide and islet amyloid polypeptide in the rat and mouse pancreas.
Volume: 269
Issue: 2
Pages: 315-22
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Publication
11246872 | J:78535
First Author: Wang J
Year: 2001
Journal: Diabetes
Title: The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Volume: 50
Issue: 3
Pages: 534-9
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Publication
14693708 | J:87252
First Author: Marzban L
Year: 2004
Journal: Diabetes
Title: Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
Volume: 53
Issue: 1
Pages: 141-8
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Publication
24627476 | J:212421
First Author: Jing G
Year: 2014
Journal: J Biol Chem
Title: Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.
Volume: 289
Issue: 17
Pages: 11807-15
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Publication
25409149 | J:218385
First Author: Venkatanarayan A
Year: 2015
Journal: Nature
Title: IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.
Volume: 517
Issue: 7536
Pages: 626-30
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Publication
36621763 | J:333476
 
First Author: Taylor AJ
Year: 2023
Journal: Mol Metab
Title: Islet amyloid polypeptide does not suppress pancreatic cancer.
Volume: 68
Pages: 101667
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Publication
16002530 | J:101574
First Author: Friis-Hansen L
Year: 2005
Journal: Endocrinology
Title: Reduced ghrelin, islet amyloid polypeptide, and peptide YY expression in the stomach of gastrin-cholecystokinin knockout mice.
Volume: 146
Issue: 10
Pages: 4464-71
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Protein Coding Gene
MGP_CAROLIEiJ_G0029028 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030532 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031124 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030259 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022789 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030083 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29250032 | J:299549
 
First Author: Abegg K
Year: 2017
Journal: Front Endocrinol (Lausanne)
Title: Involvement of Amylin and Leptin in the Development of Projections from the Area Postrema to the Nucleus of the Solitary Tract.
Volume: 8
Pages: 324
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Publication
38455055 | J:345893
 
First Author: Wenzlau JM
Year: 2024
Journal: Front Immunol
Title: Mapping of a hybrid insulin peptide in the inflamed islet β-cells from NOD mice.
Volume: 15
Pages: 1348131
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Publication
29066284 | J:271932
First Author: Liu M
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Amylin and diabetic cardiomyopathy - amylin-induced sarcolemmal Ca2+ leak is independent of diabetic remodeling of myocardium.
Volume: 1864
Issue: 5 Pt B
Pages: 1923-1930
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Publication
30943041 | J:276844
First Author: Lutz TA
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Endogenous amylin contributes to birth of microglial cells in arcuate nucleus of hypothalamus and area postrema during fetal development.
Volume: 316
Issue: 6
Pages: R791-R801
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Publication
11145110 | J:66276
First Author: Mulder H
Year: 2000
Journal: Metabolism
Title: Differential changes in islet amyloid polypeptide (amylin) and insulin mRNA expression after high-fat diet-induced insulin resistance in C57BL/6J mice.
Volume: 49
Issue: 12
Pages: 1518-22
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GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2654723
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2654723
Age: embryonic day 12.0
Specimen Label: 12
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2654723
Age: embryonic day 13.0
Specimen Label: 13
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2654723
Age: embryonic day 14.0
Specimen Label: 14
Detected: true
Specimen Num: 4
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•
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2654723
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:2654723
Age: embryonic day 16.0
Specimen Label: 16
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_07
Specimen Label: euxassay_005705_07
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_08
Specimen Label: euxassay_005705_08
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_09
Specimen Label: euxassay_005705_09
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_12
Specimen Label: euxassay_005705_12
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_13
Specimen Label: euxassay_005705_13
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_14
Specimen Label: euxassay_005705_14
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6323656
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6324020
Age: embryonic day 18.5
Image: 7I
Specimen Label: 7I
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6441722
Age: postnatal adult
Note: Expression in beta and delta cells, but rarely in alpha cells.
Specimen Label: adult pancreas not shown
Detected: true
Specimen Num: 6
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