|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 254 for Iapp

<< First    < Previous  |  Next >    Last >>
0.04s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3375 | IAPP
Type: gene
Organism: human
•
•
•
•
•
Gene
100138011 | IAPP
Type: gene
Organism: cattle
•
•
•
•
•
Gene
396362 | IAPP
Type: gene
Organism: chicken
•
•
•
•
•
Gene
100334757 | iapp
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
114670806 | IAPP
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
116409452 | iapp
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
key_18915 | IAPP
Type: gene
Organism: sheep
•
•
•
•
•
Gene
24476 | Iapp
Type: gene
Organism: rat
•
•
•
•
•
Gene
403909 | IAPP
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
741937 | IAPP
Type: gene
Organism: chimpanzee
•
•
•
•
•
Protein Coding Gene
MGI:96382 | Iapp
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Domain
IPR000443 | IAPP
Type: Family
Description: Islet amyloid polypeptide (IAPP) (also known as diabetes-associated peptideor amylin) is a pancreatic islet hormone that is stored with insulin in betacell granules []. IAPP has a propensity to form islet cell-disrupting amyloid deposits, and opposes the action of insulin in peripheral tissues; the peptide may therefore have a significant role in the development of Type2 diabetes mellitus []. It is thought that an intrinsic structural motif ofIAPP, which only occurs in species that develop age-associated or Type 2 diabetes (e.g., Homo sapiens (Human) and Felis silvestris catus (Cat)), is linked to its amyloidogenicity [].IAPP is a short, 37-residue peptide. The hormone selectively inhibits insulin-stimulated glucose utilisation and glycogen deposition in muscle,but does not affect adipocyte glucose metabolism. The sequences of amylinand the calcitonin gene-related peptides (CGRPs) show strong similarity:both peptides have a conserved N-terminal intramolecular disulphide bridge,and both have a C-terminal glycine, which suggests that the C-terminalresidue of amylin, like that of CGRP, is amidated [].Near- and far-UV CD spectra of human alpha CGRP, analogues and fragments ofCGRP, and amylin have been recorded in aqueous solution and in trifluoro-ethanol/water mixtures []. The peptides were shown to contain significantamounts of α-helix in aqueous solution, this amount increasing upon addition of TFE. Amylin appears to contain less helix than CGRP [].
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6441722
Age: embryonic day 18.5
Image: 3 e18.5 IAPP
Note: Proportion of Gcg-expressing cells expressing Iapp falls to approximately 20%.
Specimen Label: 3 e18.5 IAPP
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6441723
Age: embryonic day 10.5
Image: 4 IAPP
Note: Most Iapp-expressing cells do not express Pdx1.
Specimen Label: 4 IAPP
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6441722
Age: embryonic day 12.5
Image: 3 e12.5 (upper) IAPP
Note: Co-expression with proglucagon continues throughout fetal development of pancreas. At E12.5, co-expression in majority of Gcg-expressing cells.
Specimen Label: 3 e12.5 (upper) IAPP
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6441722
Age: embryonic day 12.5
Image: 3 e12.5 (lower) IAPP
Note: Expression in all insulin-expressing cells.
Specimen Label: 3 e12.5 (lower) IAPP
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6441722
Age: embryonic day 15.5
Image: 3 e15.5 IAPP
Note: Expression in about 60% of Gcg-expressing cells.
Specimen Label: 3 e15.5 IAPP
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825756
Age: embryonic day 14.5
Image: Additional file 4 Iapp
Specimen Label: Additional file 4 Iapp
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6441722
Age: embryonic day 10.5
Image: 3 e10.5 IAPP
Note: Expression in pancreatic bud first appears at E10.5. Co-expression with proglucagon.
Specimen Label: 3 e10.5 IAPP
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
2192709 | -
First Author: Jordan K
Year: 1990
Journal: Biochem Biophys Res Commun
Title: Canine IAPP cDNA sequence provides important clues regarding diabetogenesis and amyloidogenesis in type 2 diabetes.
Volume: 169
Issue: 2
Pages: 502-8
•
•
•
•
•
Publication
28765400 | J:244694
First Author: Mukherjee A
Year: 2017
Journal: J Exp Med
Title: Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism.
Volume: 214
Issue: 9
Pages: 2591-2610
•
•
•
•
•
Publication
- | J:23849
 
First Author: Prochazka M
Year: 1991
Journal: Mouse Genome
Title: Mapping of Iapp and Kap genes to Chr. 6
Volume: 89
Pages: 553
•
•
•
•
•
Publication
- | J:20644
     
First Author: Prochazka M
Year: 1991
Journal: Personal Communication
Title: Linkage of mouse NKR P1 gene to Ly-49 and Iapp on Chromosome 6
•
•
•
•
•
Protein
P12968
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
•
•
•
•
•
Publication
2039456 | -
 
First Author: Hubbard JA
Year: 1991
Journal: Biochem J
Title: Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin.
Volume: 275 ( Pt 3)
Pages: 785-8
•
•
•
•
•
Publication
2690069 | -
First Author: Roberts AN
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Molecular and functional characterization of amylin, a peptide associated with type 2 diabetes mellitus.
Volume: 86
Issue: 24
Pages: 9662-6
•
•
•
•
•
Publication
12049785 | J:77320
First Author: Wilson ME
Year: 2002
Journal: Mech Dev
Title: Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas.
Volume: 115
Issue: 1-2
Pages: 171-6
•
•
•
•
•
Publication
26209627 | J:319572
First Author: Viret C
Year: 2015
Journal: J Immunol
Title: The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens.
Volume: 195
Issue: 5
Pages: 1964-73
•
•
•
•
•
Publication
8692984 | J:47215
First Author: Janson J
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.
Volume: 93
Issue: 14
Pages: 7283-8
•
•
•
•
•
Publication
32728889 | J:298717
First Author: Templin AT
Year: 2020
Journal: Diabetologia
Title: Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
Volume: 63
Issue: 11
Pages: 2385-2395
•
•
•
•
•
Publication
8690157 | J:73886
First Author: Couce M
Year: 1996
Journal: Diabetes
Title: Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction.
Volume: 45
Issue: 8
Pages: 1094-101
•
•
•
•
•
Publication
23229548 | J:335478
First Author: Aston-Mourney K
Year: 2013
Journal: J Biol Chem
Title: Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide.
Volume: 288
Issue: 5
Pages: 3553-9
•
•
•
•
•
Publication
27393137 | J:237059
First Author: Meier DT
Year: 2016
Journal: Diabetologia
Title: The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
Volume: 59
Issue: 10
Pages: 2166-71
•
•
•
•
•
Publication
12086946 | J:132801
First Author: Geisler JG
Year: 2002
Journal: Diabetes
Title: Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.
Volume: 51
Issue: 7
Pages: 2158-69
•
•
•
•
•
Publication
24843557 | J:241122
First Author: Hiddinga HJ
Year: 2012
Journal: J Diabetes Investig
Title: Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance.
Volume: 3
Issue: 2
Pages: 138-47
•
•
•
•
•
Publication
15899941 | J:101262
First Author: Hull RL
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice.
Volume: 289
Issue: 4
Pages: E703-9
•
•
•
•
•
Publication
11679429 | J:72413
First Author: Wang F
Year: 2001
Journal: Diabetes
Title: Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.
Volume: 50
Issue: 11
Pages: 2514-20
•
•
•
•
•
Publication
12637985 | J:82403
First Author: Vidal J
Year: 2003
Journal: Diabetologia
Title: The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
Volume: 46
Issue: 1
Pages: 71-9
•
•
•
•
•
Publication
11118007 | J:66008
First Author: Andrikopoulos S
Year: 2000
Journal: Diabetes
Title: beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
Volume: 49
Issue: 12
Pages: 2056-62
•
•
•
•
•
Publication
8495745 | J:83219
First Author: Fox N
Year: 1993
Journal: FEBS Lett
Title: Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).
Volume: 323
Issue: 1-2
Pages: 40-4
•
•
•
•
•
Publication
35136064 | J:333177
First Author: Fukumitsu K
Year: 2022
Journal: Nat Commun
Title: Amylin-Calcitonin receptor signaling in the medial preoptic area mediates affiliative social behaviors in female mice.
Volume: 13
Issue: 1
Pages: 709
•
•
•
•
•
Publication
9278863 | J:42671
First Author: Ekawa K
Year: 1997
Journal: J Mol Endocrinol
Title: Cloning of mouse islet amyloid polypeptide gene and characterization of its promoter.
Volume: 19
Issue: 1
Pages: 79-86
•
•
•
•
•
Publication
9753619 | J:50042
First Author: Gebre-Medhin S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin).
Volume: 250
Issue: 2
Pages: 271-7
•
•
•
•
•
Publication
11474116 | J:134181
First Author: Westermark GT
Year: 2000
Journal: Mol Med
Title: Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP.
Volume: 6
Issue: 12
Pages: 998-1007
•
•
•
•
•
Publication
11751075 | J:73918
First Author: Carlsson PO
Year: 2002
Journal: Eur J Endocrinol
Title: Unaltered pancreatic islet blood perfusion in islet amyloid polypeptide-deficient mice.
Volume: 146
Issue: 1
Pages: 107-12
•
•
•
•
•
Publication
21734016 | J:186801
First Author: Delong T
Year: 2011
Journal: Diabetes
Title: Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.
Volume: 60
Issue: 9
Pages: 2325-30
•
•
•
•
•
Publication
25700985 | J:220250
First Author: Oskarsson ME
Year: 2015
Journal: Am J Pathol
Title: In vivo seeding and cross-seeding of localized amyloidosis: a molecular link between type 2 diabetes and Alzheimer disease.
Volume: 185
Issue: 3
Pages: 834-46
•
•
•
•
•
Publication
10751203 | J:62402
First Author: Mulder H
Year: 2000
Journal: Am J Physiol Endocrinol Metab
Title: Islet amyloid polypeptide (amylin)-deficient mice develop a more severe form of alloxan-induced diabetes.
Volume: 278
Issue: 4
Pages: E684-91
•
•
•
•
•
Publication
11731221 | J:73308
First Author: Jaikaran ET
Year: 2001
Journal: Biochim Biophys Acta
Title: Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
Volume: 1537
Issue: 3
Pages: 179-203
•
•
•
•
•
Publication
8076756 | J:20486
First Author: Mulder H
Year: 1994
Journal: Gastroenterology
Title: Islet amyloid polypeptide is expressed in endocrine cells of the gastric mucosa in the rat and mouse.
Volume: 107
Issue: 3
Pages: 712-9
•
•
•
•
•
Publication
10230646 | J:54393
First Author: Höppener JW
Year: 1999
Journal: Diabetologia
Title: Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
Volume: 42
Issue: 4
Pages: 427-34
•
•
•
•
•
Publication
26786104 | J:233729
First Author: Westwell-Roper C
Year: 2016
Journal: J Biol Chem
Title: Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
Volume: 291
Issue: 17
Pages: 8908-17
•
•
•
•
•
Publication
2668946 | J:9937
First Author: Nishi M
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.
Volume: 86
Issue: 15
Pages: 5738-42
•
•
•
•
•
Publication
9838101 | J:51556
First Author: Gebre-Medhin S
Year: 1998
Journal: Brain Res Mol Brain Res
Title: Reduced nociceptive behavior in islet amyloid polypeptide (amylin) knockout mice.
Volume: 63
Issue: 1
Pages: 180-3
•
•
•
•
•
Publication
24043895 | J:206266
First Author: Baker RL
Year: 2013
Journal: J Immunol
Title: Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.
Volume: 191
Issue: 8
Pages: 3990-4
•
•
•
•
•
Publication
1423499 | J:2137
First Author: Ahrén B
Year: 1992
Journal: Cell Tissue Res
Title: Localization of calcitonin gene-related peptide and islet amyloid polypeptide in the rat and mouse pancreas.
Volume: 269
Issue: 2
Pages: 315-22
•
•
•
•
•
Publication
11246872 | J:78535
First Author: Wang J
Year: 2001
Journal: Diabetes
Title: The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Volume: 50
Issue: 3
Pages: 534-9
•
•
•
•
•
Publication
14693708 | J:87252
First Author: Marzban L
Year: 2004
Journal: Diabetes
Title: Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
Volume: 53
Issue: 1
Pages: 141-8
•
•
•
•
•
Publication
24627476 | J:212421
First Author: Jing G
Year: 2014
Journal: J Biol Chem
Title: Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.
Volume: 289
Issue: 17
Pages: 11807-15
•
•
•
•
•
Publication
16002530 | J:101574
First Author: Friis-Hansen L
Year: 2005
Journal: Endocrinology
Title: Reduced ghrelin, islet amyloid polypeptide, and peptide YY expression in the stomach of gastrin-cholecystokinin knockout mice.
Volume: 146
Issue: 10
Pages: 4464-71
•
•
•
•
•
Publication
36621763 | J:333476
 
First Author: Taylor AJ
Year: 2023
Journal: Mol Metab
Title: Islet amyloid polypeptide does not suppress pancreatic cancer.
Volume: 68
Pages: 101667
•
•
•
•
•
Publication
25409149 | J:218385
First Author: Venkatanarayan A
Year: 2015
Journal: Nature
Title: IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.
Volume: 517
Issue: 7536
Pages: 626-30
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0029028 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0031460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0031435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0031363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0031442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0031164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_96382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0031904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0030532 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0031124 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0031281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0031232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0031365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0031272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0031936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0030259 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0030625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0022789 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0030083 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
30943041 | J:276844
First Author: Lutz TA
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Endogenous amylin contributes to birth of microglial cells in arcuate nucleus of hypothalamus and area postrema during fetal development.
Volume: 316
Issue: 6
Pages: R791-R801
•
•
•
•
•
Publication
38455055 | J:345893
 
First Author: Wenzlau JM
Year: 2024
Journal: Front Immunol
Title: Mapping of a hybrid insulin peptide in the inflamed islet β-cells from NOD mice.
Volume: 15
Pages: 1348131
•
•
•
•
•
Publication
29066284 | J:271932
First Author: Liu M
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Amylin and diabetic cardiomyopathy - amylin-induced sarcolemmal Ca2+ leak is independent of diabetic remodeling of myocardium.
Volume: 1864
Issue: 5 Pt B
Pages: 1923-1930
•
•
•
•
•
Publication
29250032 | J:299549
 
First Author: Abegg K
Year: 2017
Journal: Front Endocrinol (Lausanne)
Title: Involvement of Amylin and Leptin in the Development of Projections from the Area Postrema to the Nucleus of the Solitary Tract.
Volume: 8
Pages: 324
•
•
•
•
•
Publication
11145110 | J:66276
First Author: Mulder H
Year: 2000
Journal: Metabolism
Title: Differential changes in islet amyloid polypeptide (amylin) and insulin mRNA expression after high-fat diet-induced insulin resistance in C57BL/6J mice.
Volume: 49
Issue: 12
Pages: 1518-22
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2654723
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2654723
Age: embryonic day 12.0
Specimen Label: 12
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2654723
Age: embryonic day 13.0
Specimen Label: 13
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2654723
Age: embryonic day 14.0
Specimen Label: 14
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2654723
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2654647
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:2654723
Age: embryonic day 16.0
Specimen Label: 16
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_07
Specimen Label: euxassay_005705_07
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_08
Specimen Label: euxassay_005705_08
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_09
Specimen Label: euxassay_005705_09
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_12
Specimen Label: euxassay_005705_12
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_13
Specimen Label: euxassay_005705_13
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:901517
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825493
Age: embryonic day 14.5
Image: euxassay_005705_14
Specimen Label: euxassay_005705_14
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6323656
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6324020
Age: embryonic day 18.5
Image: 7I
Specimen Label: 7I
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6441708
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6441722
Age: postnatal adult
Note: Expression in beta and delta cells, but rarely in alpha cells.
Specimen Label: adult pancreas not shown
Detected: true
Specimen Num: 6
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom