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Search results 1 to 100 out of 401 for Ica1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Islet cell autoantigen 69kDa (ICA69) or islet cell autoantigen 1 was identified with a group of type 1 diabetes-related islet autoantigens []. ICA69 is enriched in the Golgi complex, and its N-terminal half contains a BAR-domain []. ICA69 forms heteromeric BAR-domain complexes with another cytosolic lipid-binding protein, PICK1. Together they are key regulators of the formation and maturation of insulin granules [].
Gene
Type: gene
Organism: human
Publication
First Author: Pietropaolo M
Year: 1993
Journal: J Clin Invest
Title: Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen.
Volume: 92
Issue: 1
Pages: 359-71
Publication
First Author: Cao M
Year: 2013
Journal: PLoS Biol
Title: PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance.
Volume: 11
Issue: 4
Pages: e1001541
Publication
First Author: Bonner SM
Year: 2012
Journal: J Biol Chem
Title: Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.
Volume: 287
Issue: 21
Pages: 17882-17893
Protein
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 465  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
Publication
First Author: Buffa L
Year: 2008
Journal: Eur J Cell Biol
Title: ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells.
Volume: 87
Issue: 4
Pages: 197-209
Publication
First Author: Pilon M
Year: 2000
Journal: Mol Biol Cell
Title: The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion.
Volume: 11
Issue: 10
Pages: 3277-88
Publication
First Author: Gaedigk R
Year: 1996
Journal: Genomics
Title: Genomic organization and transcript analysis of ICAp69, a target antigen in diabetic autoimmunity.
Volume: 38
Issue: 3
Pages: 382-91
Publication  
First Author: Chiu SL
Year: 2023
Journal: Front Mol Neurosci
Title: ICA69 regulates activity-dependent synaptic strengthening and learning and memory.
Volume: 16
Pages: 1171432
Publication
First Author: Han K
Year: 2019
Journal: Pain
Title: Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice.
Volume: 160
Issue: 3
Pages: 712-723
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Karges W
Year: 1997
Journal: Biochim Biophys Acta
Title: Molecular cloning of murine ICA69: diabetes-prone mice recognize the human autoimmune-epitope, Tep69, conserved in splice variants from both species.
Volume: 1360
Issue: 2
Pages: 97-101
Publication
First Author: Winer S
Year: 2002
Journal: J Immunol
Title: ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.
Volume: 168
Issue: 1
Pages: 475-82
Publication
First Author: Konno A
Year: 2007
Journal: Immunogenetics
Title: Identification of a quantitative trait locus regulating B cell-dominant infiltration into autoimmune sialitis lesions of the IQI mouse model of primary Sjögren's syndrome.
Volume: 59
Issue: 11
Pages: 853-9
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: thyroid
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: ovary
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: adrenal
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: muscle
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: pancreas
Detected: true
Specimen Num: 10
GXD Expression        
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4460954
Age: postnatal adult
Specimen Label: liver
Specimen Num: 11
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:4460955
Age: embryonic day 18.0
Specimen Label: fetal brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4460955
Age: postnatal adult
Specimen Label: adult brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:4460955
Age: embryonic day 18.0
Specimen Label: fetal heart
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4460955
Age: postnatal adult
Specimen Label: adult heart
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:4460955
Age: embryonic day 18.0
Specimen Label: fetal liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4460955
Age: postnatal adult
Specimen Label: adult liver
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:4460955
Age: embryonic day 18.0
Specimen Label: fetal pancreas
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4460927
Assay Type: RT-PCR
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:4460955
Age: postnatal adult
Specimen Label: adult pancreas
Detected: true
Specimen Num: 8
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: heart
Specimen Num: 1
GXD Expression      
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: spleen
Specimen Num: 3
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: lung
Specimen Num: 4
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: liver
Specimen Num: 5
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: muscle
Specimen Num: 6
GXD Expression        
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: kidney
Specimen Num: 7
GXD Expression      
Probe: MGI:4460934
Assay Type: Northern blot
Annotation Date: 2010-07-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4460956
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: heart
Specimen Num: 2
GXD Expression        
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: kidney
Specimen Num: 3
GXD Expression        
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: liver
Specimen Num: 4
GXD Expression        
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: muscle
Specimen Num: 5
GXD Expression      
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: pancreas
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4460949
Assay Type: Western blot
Annotation Date: 2010-07-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4460958
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6719283
Age: embryonic day 14.5
Specimen Label: E 14.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:6719283
Age: embryonic day 18.0
Specimen Label: E 18
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:6719283
Age: postnatal day 2
Specimen Label: P 2
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719283
Age: postnatal day 10
Specimen Label: P 10
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719283
Age: postnatal day 30
Specimen Label: P 30
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6719275
Assay Type: RT-PCR
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719283
Age: postnatal day 60
Specimen Label: P 60
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:6719285
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:6719285
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:6719285
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:6719285
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:6719285
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:6719285
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719285
Age: postnatal day 60
Specimen Label: P60
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719285
Age: postnatal day 60
Specimen Label: P60
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6719280
Assay Type: Western blot
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6719285
Age: postnatal day 60
Specimen Label: P60
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6831101
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6831196
Age: embryonic day 15.0
Image: 3
Specimen Label: E15
Detected: true
Specimen Num: 1