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Search results 1 to 100 out of 169 for Icam2

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Type Details Score
Gene
3384 | ICAM2
Type: gene
Organism: human
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Gene
574158 | ICAM2
Type: gene
Organism: macaque, rhesus
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Gene
119873251 | ICAM2
Type: gene
Organism: dog, domestic
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Gene
360647 | Icam2
Type: gene
Organism: rat
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Gene
494137 | ICAM2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:96394 | Icam2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR015653 | ICAM2
Type: Family
Description: Intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation, immune responses and in intracellular signalling events []. The ICAM family consists of five members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 during inflammation and in immune responses. In addition, ICAMs may exist in soluble forms in human plasma, due to activation and proteolysis mechanisms at cell surfaces.ICAM-1 (CD54) contains five Ig-like domains. It is expressed on leucocytes, endothelial and epithelial cells, and is upregulated in response to bacterial invasion. The protein is a ligand for lymphocyte-function associated (LFA) antigens and also a receptor for CD11a,b/CD18, fibrinogen, human rhinovirus and Plasmodium falciparum-infected erythrocytes. ICAM-1 binding sites for CD11a/CD18 and its other binding partners are located in the first domain and are overlapping. ICAM-1 domain 2 seems to play an important role in maintaining the conformation of domain 1 and particularly the structural integrity of the LFA-1 ligand-binding site [].The 3-dimensional atomic structure of the tandem N-terminal Ig-like domains (D1 and D2) of ICAM-1 has been determined to 2.2A resolution and fitted into a cryoelectron microscopy reconstruction of a rhinovirus-ICAM-1 complex []. Extensive charge interactions between ICAM-1 and human rhinovirusesare largely conserved in major and minor receptor groups of rhinoviruses. The interaction of ICAMs with LFA-1 is mediated by a divalent cation bound to the insertion (I)-domain on the alpha chain of LFA-1 and the carboxyl group of a conserved glutamic acid residue on ICAMs.ICAM-2 (CD102) has two Ig-like domains. It is expressed on endothelial cells, leucocytes and platelets, and binds to CD11a'b/CD18. The protein is refractory to proinflammatory cytokines, and plays an important role in the adhesion of leucocytes to the uninduced endothelium [].ICAM-3 (CD50) contains five Ig-like domains and binds to leucocyte integrins CD11a'd/CD18. The protein plays an important role in the immune response and perhaps in signal transduction [].ICAM-4 (LW blood group Ag) is red blood cell (RBC) specific and binds to CD11a'b/CD18. It is associated with the RBC Rh antigens and could be important in retaining immature red cells in the bone marrow, or in the uptake of senescent cells into the spleen [].ICAM-5 (telencephalin) has nine Ig-like domains and is confined to the telencephalon of the brain. The role of this CD11a/CD18 binding molecule is not yet known [].VCAM-1 was first described as a cytokine-inducible endothelial adhesion molecule. It can bind to leucocyte integrin VL-4 (very late antigen-4) to recruit leucocytes to sites of inflammation []. The predominant form of VCAM-1 in vivo has an N-terminal extracellular region comprising seven Ig-like domains []. A conserved integrin-binding motif has been identified in domains 1 and 4, variants of which are present in the N-terminal domain of all members of the integrin-binding subgroup of the immunoglobulin superfamily. The structure of a VLA-4-binding fragment comprising the first two domains of VCAM-1 has been determined to 1.8A resolution. The integrin-binding motif is exposed and forms the N-terminal region of the loop between β-strands C and D of domain 1 []. VCAM-1 domains 1 and 2 are structurally similar to ICAM-1 and ICAM-2 [].Regulation of binding between integrins and their ICAM partners influences the ability of leukocytes interact with neurons [], to cross the blood-brain barrier [], to migrate through the vasculature [], and to interact with antigen-presenting cells []. This entry represents ICAM-2, a close relative of ICAM-1, which shares shares LFA-1, a leukocyte-expressed integrin, as its binding partner []. The two proteins have substantially overlapping functions.
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Protein
P35330
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: false
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Protein
B1ARJ2
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
G3UWJ5
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
G5E8M9
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: true
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Publication
10352278 | -
First Author: Kotovuori A
Year: 1999
Journal: J Immunol
Title: ICAM-2 and a peptide from its binding domain are efficient activators of leukocyte adhesion and integrin affinity.
Volume: 162
Issue: 11
Pages: 6613-20
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Publication
10725740 | -
First Author: Neelamegham S
Year: 2000
Journal: J Immunol
Title: Shear and time-dependent changes in Mac-1, LFA-1, and ICAM-3 binding regulate neutrophil homotypic adhesion.
Volume: 164
Issue: 7
Pages: 3798-805
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Publication
10846180 | -
First Author: Hermand P
Year: 2000
Journal: J Biol Chem
Title: Binding sites of leukocyte beta 2 integrins (LFA-1, Mac-1) on the human ICAM-4/LW blood group protein.
Volume: 275
Issue: 34
Pages: 26002-10
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Publication
10741396 | -
First Author: Tian L
Year: 2000
Journal: Eur J Immunol
Title: Binding of T lymphocytes to hippocampal neurons through ICAM-5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18.
Volume: 30
Issue: 3
Pages: 810-8
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Publication
11133225 | -
First Author: Lee YW
Year: 2001
Journal: J Mol Cell Cardiol
Title: IL-4-induced oxidative stress upregulates VCAM-1 gene expression in human endothelial cells.
Volume: 33
Issue: 1
Pages: 83-94
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Publication
7531291 | -
First Author: Jones EY
Year: 1995
Journal: Nature
Title: Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Volume: 373
Issue: 6514
Pages: 539-44
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Publication
9151947 | -
First Author: Gahmberg CG
Year: 1997
Journal: Eur J Biochem
Title: Leukocyte adhesion--structure and function of human leukocyte beta2-integrins and their cellular ligands.
Volume: 245
Issue: 2
Pages: 215-32
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Publication
10998349 | -
First Author: Stanley P
Year: 2000
Journal: Biochem J
Title: The second domain of intercellular adhesion molecule-1 (ICAM-1) maintains the structural integrity of the leucocyte function-associated antigen-1 (LFA-1) ligand-binding site in the first domain.
Volume: 351
Issue: Pt 1
Pages: 79-86
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Publication
9539703 | -
First Author: Bella J
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand.
Volume: 95
Issue: 8
Pages: 4140-5
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Publication
10893271 | -
First Author: Tian L
Year: 2000
Journal: J Cell Biol
Title: Intercellular adhesion molecule-5 induces dendritic outgrowth by homophilic adhesion.
Volume: 150
Issue: 1
Pages: 243-52
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Publication
12098511 | -
First Author: Dietrich JB
Year: 2002
Journal: J Neuroimmunol
Title: The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier.
Volume: 128
Issue: 1-2
Pages: 58-68
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Publication
1716919 | -
 
First Author: Dustin ML
Year: 1991
Journal: Annu Rev Immunol
Title: Role of lymphocyte adhesion receptors in transient interactions and cell locomotion.
Volume: 9
Pages: 27-66
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Publication
10398592 | -
First Author: Grakoui A
Year: 1999
Journal: Science
Title: The immunological synapse: a molecular machine controlling T cell activation.
Volume: 285
Issue: 5425
Pages: 221-7
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Publication
2497351 | -
First Author: Staunton DE
Year: 1989
Journal: Nature
Title: Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.
Volume: 339
Issue: 6219
Pages: 61-4
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Publication
25740934 | J:257336
First Author: Simecek P
Year: 2015
Journal: G3 (Bethesda)
Title: Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice.
Volume: 5
Issue: 5
Pages: 771-5
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Protein Coding Gene
MGP_CAROLIEiJ_G0017323 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019058 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018611 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019130 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018453 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018167 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1401904 | J:2867
First Author: Xu H
Year: 1992
Journal: J Immunol
Title: Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA.
Volume: 149
Issue: 8
Pages: 2650-5
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Publication
10023766 | J:54748
First Author: Gerwin N
Year: 1999
Journal: Immunity
Title: Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness.
Volume: 10
Issue: 1
Pages: 9-19
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Publication
15920013 | J:118504
First Author: Huang MT
Year: 2005
Journal: Blood
Title: Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis.
Volume: 106
Issue: 5
Pages: 1636-43
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Publication
8648141 | J:34009
First Author: Xu H
Year: 1996
Journal: J Immunol
Title: Characterization of murine intercellular adhesion molecule-2.
Volume: 156
Issue: 12
Pages: 4909-14
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GXD Expression
GXD Expression
     
Probe: MGI:3036857
Assay Type: RT-PCR
Annotation Date: 2004-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608513
Stage: TS13
Assay Id: MGI:3036858
Age: embryonic day 8.25-8.5
Specimen Label: Mut
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3036857
Assay Type: RT-PCR
Annotation Date: 2004-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608513
Stage: TS13
Assay Id: MGI:3036858
Age: embryonic day 8.25-8.5
Specimen Label: WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945033
Age: embryonic day 11.5
Image: g00479 E11.5
Specimen Label: g00479 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3056139
Assay Type: Immunohistochemistry
Annotation Date: 2004-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1637013
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3056162
Age: embryonic day 8.5
Image: 1D
Note: Expression is in endothelial cells.
Specimen Label: 1D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945033
Age: embryonic day 11.5
Image: g00479 E11.5
Specimen Label: g00479 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3056139
Assay Type: Immunohistochemistry
Annotation Date: 2006-03-02
Strength: Present
Sex: Female
Emaps: EMAPS:1795928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3614401
Age: postnatal adult
Image: 7B
Note: Expression is in the endothelial cells of the mesometrium.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3056139
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6504911
Age: embryonic day 12.5
Specimen Label: 5A insert
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945033
Age: embryonic day 11.5
Image: g00479 E11.5
Specimen Label: g00479 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945033
Age: embryonic day 11.5
Image: g00479 E11.5
Specimen Label: g00479 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3056139
Assay Type: Immunohistochemistry
Annotation Date: 2006-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3614401
Age: embryonic day 10.5
Image: 6C
Note: Expression is in endothelial cells.
Specimen Label: 6C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945033
Age: embryonic day 11.5
Image: g00479 E11.5
Specimen Label: g00479 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945033
Age: embryonic day 15.5
Image: g00479 E15.5
Specimen Label: g00479 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4886299
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945033
Age: postnatal day 7
Image: g00479 P7
Specimen Label: g00479 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
12554651 | J:116255
First Author: Hamada K
Year: 2003
Journal: EMBO J
Title: Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.
Volume: 22
Issue: 3
Pages: 502-14
•
•
•
•
•
Publication
27578049 | J:241903
 
First Author: Fan Z
Year: 2016
Journal: Nat Commun
Title: Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.
Volume: 7
Pages: 12658
•
•
•
•
•
Publication
27338806 | J:249701
First Author: Rudolph H
Year: 2016
Journal: Eur J Immunol
Title: Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro.
Volume: 46
Issue: 9
Pages: 2187-203
•
•
•
•
•
Publication
12893765 | J:86457
First Author: Lyck R
Year: 2003
Journal: Blood
Title: T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells.
Volume: 102
Issue: 10
Pages: 3675-83
•
•
•
•
•
Publication
29420172 | J:270810
First Author: Feigelson SW
Year: 2018
Journal: Cell Rep
Title: ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs.
Volume: 22
Issue: 4
Pages: 849-859
•
•
•
•
•
Publication
11937524 | J:88254
First Author: Savage ND
Year: 2002
Journal: J Immunol
Title: Polar redistribution of the sialoglycoprotein CD43: implications for T cell function.
Volume: 168
Issue: 8
Pages: 3740-6
•
•
•
•
•
Publication
16469869 | J:124850
First Author: Huang MT
Year: 2006
Journal: Blood
Title: ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration.
Volume: 107
Issue: 12
Pages: 4721-7
•
•
•
•
•
Publication
29501382 | J:265090
 
First Author: Zhao F
Year: 2018
Journal: Exp Eye Res
Title: Expression, regulation and function of miR-126 in the mouse choroid vasculature.
Volume: 170
Pages: 169-176
•
•
•
•
•
Publication
7919377 | J:20853
First Author: Ohh M
Year: 1994
Journal: Blood
Title: Regulation of intercellular adhesion molecule-1 gene expression involves multiple mRNA stabilization mechanisms: effects of interferon-gamma and phorbol myristate acetate.
Volume: 84
Issue: 8
Pages: 2632-9
•
•
•
•
•
Publication
25634957 | J:220993
First Author: Stoler-Barak L
Year: 2015
Journal: FASEB J
Title: Heparanase of murine effector lymphocytes and neutrophils is not required for their diapedesis into sites of inflammation.
Volume: 29
Issue: 5
Pages: 2010-21
•
•
•
•
•
Publication
28939548 | J:250274
First Author: Zaretsky I
Year: 2017
Journal: J Exp Med
Title: ICAMs support B cell interactions with T follicular helper cells and promote clonal selection.
Volume: 214
Issue: 11
Pages: 3435-3448
•
•
•
•
•
Publication
16981228 | J:118093
First Author: Wethmar K
Year: 2006
Journal: Eur J Immunol
Title: Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues.
Volume: 36
Issue: 10
Pages: 2781-94
•
•
•
•
•
Publication
18614175 | J:168874
First Author: Takai Y
Year: 2008
Journal: J Mol Biol
Title: Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.
Volume: 381
Issue: 3
Pages: 634-44
•
•
•
•
•
Publication
7947467 | J:19832
First Author: Kuramoto T
Year: 1994
Journal: Int Immunol
Title: The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11.
Volume: 6
Issue: 7
Pages: 991-4
•
•
•
•
•
Publication
25545837 | J:228982
First Author: Abadier M
Year: 2015
Journal: Eur J Immunol
Title: Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier.
Volume: 45
Issue: 4
Pages: 1043-58
•
•
•
•
•
Publication
20395417 | J:298175
First Author: Boscacci RT
Year: 2010
Journal: Blood
Title: Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing.
Volume: 116
Issue: 6
Pages: 915-25
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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